Immunomodulatory effect of swine CCL20 chemokine in DNA vaccination against CSFV

Veterinary Immunology and Immunopathology

Volumn 142, Issue 3-4, 2011, Pages 243-251

  Tarradas, Joan ^a   Álvarez, Belen ^b   Fraile, Lorenzo ^a,c   Rosell, Rosa ^a,d   Muñoz, Marta ^a   Galindo Cardiel, Iván ^a,e   Domingo, Mariano ^a,e   Dominguez, Javier ^b   Ezquerra, Angel ^b   Sobrino, Francisco ^f   Ganges, Llilianne ^a  

^a CENTRE DE RECERCA EN SANITAT ANIMAL CRESA   (Spain)

^b INIA   (Spain)

^c UNIVERSITY OF LLEIDA   (Spain)

^d GENERALITAT DE CATALUNYA   (Spain)

^e UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^f CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

CCL20 chemokine; Cellular and humoral immune response; Classical swine fever virus; DNA vaccine; Immunomodulatory

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; GLYCOPROTEIN E2; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA IMMUNIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; FLOW CYTOMETRY; HELPER CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOMODULATION; INOCULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PESTIVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; VIRUS DETECTION; VIRUS LOAD; VIRUS REPLICATION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, VIRAL; BASE SEQUENCE; CHEMOKINE CCL20; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNIZATION; IMMUNOLOGIC FACTORS; INTERFERON-GAMMA; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SWINE; VACCINES, DNA; VIRAL VACCINES;

ANIMALIA; CLASSICAL SWINE FEVER VIRUS; SUIDAE;

EID: 79960050972     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2011.05.024     Document Type: Article

References (42)

1. Beer M., Reimann I., Hoffmann B., Depner K. Novel marker vaccines against classical swine fever. Vaccine 2007, 25:5665-5670.
2. Charo I.F., Ransohoff R.M. The many roles of chemokines and chemokine receptors in inflammation. New Engl. J. Med. 2006, 354:610-621.
3. Chavan R., Marfatia K.A., An I.C., Garber D.A., Feinberg M.B. Expression of CCL20 and granulocyte-macrophage colony-stimulating factor, but not Flt3-L, from modified vaccinia virus Ankara enhances antiviral cellular and humoral immune responses. J. Virol. 2006, 80:7676-7687.
4. Comerford I., Bunting M., Fenix K., Haylock-Jacobs S., Litchfield W., Harata-Lee Y., Turvey M., Brazzatti J., Gregor C., Nguyen P., Kara E., McColl S.R. An immune paradox: how can the same chemokine axis regulate both immune tolerance and activation?: CCR6/CCL20: a chemokine axis balancing immunological tolerance and inflammation in autoimmune disease. Bioessays 2010, 32:1067-1076.
5. de Arce H.D., Ganges L., Barrera M., Naranjo D., Sobrino F., Frias M.T., Nunez J.I. Origin and evolution of viruses causing classical swine fever in Cuba. Virus Res. 2005, 112:123-131.
6. Diaz de Arce H., Artursson K., L'Haridon R., Perers A., La Bonnardiere C., Alm G.V. A sensitive immunoassay for porcine interferon-alpha. Vet. Immunol. Immunopathol. 1992, 30:319-327.
7. Diaz I., Mateu E. Use of ELISPOT and ELISA to evaluate IFN-gamma, IL-10 and IL-4 responses in conventional pigs. Vet. Immunol. Immunopathol. 2005, 106:107-112.
8. Dong X.N., Chen Y.H. Candidate peptide-vaccines induced immunity against CSFV and identified sequential neutralizing determinants in antigenic domain A of glycoprotein E2. Vaccine 2006, 24:1906-1913.
9. Ganges L., Barrera M., Nunez J.I., Blanco I., Frias M.T., Rodriguez F., Sobrino F. A DNA vaccine expressing the E2 protein of classical swine fever virus elicits T cell responses that can prime for rapid antibody production and confer total protection upon viral challenge. Vaccine 2005, 23:3741-3752.
10. Ganges L., Nunez J.I., Sobrino F., Borrego B., Fernandez-Borges N., Frias-Lepoureau M.T., Rodriguez F. Recent advances in the development of recombinant vaccines against classical swine fever virus: cellular responses also play a role in protection. Vet. J. 2008, 177:169-177.
11. Guo J.H., Fan M.W., Sun J.H., Jia R. Fusion of antigen to chemokine CCL20 Or CXCL13 strategy to enhance DNA vaccine potency. Int. Immunopharmacol. 2009, 9:925-930.
12. Guzylack-Piriou L., Balmelli C., McCullough K.C., Summerfield A. Type-A CpG oligonucleotides activate exclusively porcine natural interferon-producing cells to secrete interferon-alpha, tumour necrosis factor-alpha and interleukin-12. Immunology 2004, 112:28-37.
13. Hoffmann B., Beer M., Schelp C., Schirrmeier H., Depner K. Validation of a real-time RT-PCR assay for sensitive and specific detection of classical swine fever. J. Virol. Methods 2005, 130:36-44.
14. Hulst M.M., Westra D.F., Wensvoort G., Moormann R.J. Glycoprotein E1 of Hog cholera virus expressed in insect cells protects swine from hog cholera. J. Virol. 1993, 67:5435-5442.
15. Hung L.H., Li H.P., Lien Y.Y., Wu M.L., Chaung H.C. Adjuvant effects of chicken interleukin-18 in Avian Newcastle disease vaccine. Vaccine 2010, 28:1148-1155.
16. Huygen K. Plasmid DNA vaccination. Microbes Infect. 2005, 7:932-938.
17. Kaden V., Heyne H., Kiupel H., Letz W., Kern B., Lemmer U., Gossger K., Rothe A., Bohme H., Tyrpe P. Oral immunisation of wild boar against classical swine fever: concluding analysis of the recent field trials in Germany. Berl. Munch. Tierarztl. Wochenschr. 2002, 115:179-185.
18. Kaufmann I., Eisner C., Richter P., Huge V., Beyer A., Chouker A., Schelling G., Thiel M. Lymphocyte subsets and the role of TH1/TH2 balance in stressed chronic pain patients. Neuroimmunomodulation 2007, 14:272-280.
19. Konig M., Lengsfeld T., Pauly T., Stark R., Thiel H.J. Classical swine fever virus: independent induction of protective immunity by two structural glycoproteins. J. Virol. 1995, 69:6479-6486.
20. Kraynyak K.A., Kutzler M.A., Cisper N.J., Khan A.S., Draghia-Akli R., Sardesal N.Y., Lewis M.G., Yan J., Weiner D.B. Systemic immunization with CCL27/CTACK modulates immune responses at mucosal sites in mice and macaques. Vaccine 2010, 28:1942-1951.
21. Learmonth G.S., Love D.N., Gilkerson J.R., Wellington J.E., Whalley J.M. Inoculation with DNA encoding the glycoprotein gp2 reduces severity of equine herpesvirus 1 infection in a mouse respiratory model. Arch. Virol. 2003, 148:1805-1813.
22. Leifer I., Everett H., Hoffmann B., Sosan O., Crooke H., Beer M., Blome S. Escape of classical swine fever C-strain vaccine virus from detection by C-strain specific real-time RT-PCR caused by a point mutation in the primer-binding site. J. Virol. Methods 2010, 166:98-100.
23. Moennig V., Floegel-Niesmann G., Greiser-Wilke I. Clinical signs and epidemiology of classical swine fever: a review of new knowledge. Vet. J. 2003, 165:11-20.
24. OIE Classical Swine Fever (Hog Cholera). Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2008, Office International des Epizooties, Paris, France, pp. 1092-1106.
25. Reed L.J., Muench H. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 1938, 27:493-497.
26. Rodriguez F., Whitton J.L. Enhancing DNA immunization. Virology 2000, 268:233-238.
27. Rumenapf T., Stark R., Meyers G., Thiel H.J. Structural proteins of hog cholera virus expressed by vaccinia virus: further characterization and induction of protective immunity. J. Virol. 1991, 65:589-597.
28. Sallusto F., Lanzavecchia A. Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression. Immunol. Rev. 2000, 177:134-140.
29. Scheerlinck J.P., Casey G., McWaters P., Kelly J., Woollard D., Lightowlers M.W., Tennent J.M., Chaplin P.J. The immune response to a DNA vaccine can be modulated by co-delivery of cytokine genes using a DNA prime-protein boost strategy. Vaccine 2001, 19:4053-4060.
30. Schutyser E., Struyf S., Van Damme J. The CC chemokine CCL20 and its receptor CCR6. Cytokine Growth Factor Rev. 2003, 14:409-426.
31. Summerfield A., Alves M., Ruggli N., de Bruin M.G., McCullough K.C. High IFN-alpha responses associated with depletion of lymphocytes and natural IFN-producing cells during classical swine fever. J. Interferon Cytokine Res. 2006, 26:248-255.
32. Takashima A., Morita A. Dendritic cells in genetic immunization. J. Leukoc. Biol. 1999, 66:350-356.
33. Tarradas J., Argilaguet J.M., Rosell R., Nofrarias M., Crisci E., Cordoba L., Perez-Martin E., Diaz I., Rodriguez F., Domingo M., Montoya M., Ganges L. Interferon-gamma induction correlates with protection by DNA vaccine expressing E2 glycoprotein against classical swine fever virus infection in domestic pigs. Vet. Microbiol. 2010, 142:51-58.
34. Terpstra C., Bloemraad M., Gielkens A.L. The neutralizing peroxidase-linked assay for detection of antibody against swine fever virus. Vet. Microbiol. 1984, 9:113-120.
35. Torlone V., Titoli F., Gialletti L. Circulating interferon production in pigs infected with hog cholera virus. Life Sci. 1965, 4:1707-1713.
36. Van Regenmortel M.H.V. Virus Taxonomy Classification and Nomenclature of Viruses: Seventh Report of the International Committee on Taxonomy of Viruses 2000, Academic Press, San Diego.
37. van Zijl M., Wensvoort G., de Kluyver E., Hulst M., van der Gulden H., Gielkens A., Berns A., Moormann R. Live attenuated pseudorabies virus expressing envelope glycoprotein E1 of hog cholera virus protects swine against both pseudorabies and hog cholera. J. Virol. 1991, 65:2761-2765.
38. Wensvoort G., Terpstra C., Boonstra J., Bloemraad M., Van Zaane D. Production of monoclonal antibodies against swine fever virus and their use in laboratory diagnosis. Vet. Microbiol. 1986, 12:101-108.
39. Westermann J., Nguyen-Hoai T., Baldenhofer G., Hopken U.E., Lipp M., Dorken B., Pezzutto A. CCL19 (ELC) as an adjuvant for DNA vaccination: induction of a TH1-type T-cell response and enhancement of antitumor immunity. Cancer Gene Ther. 2007, 14:523-532.
40. Wienhold D., Armengol E., Marquardt A., Marquardt C., Voigt H., Buttner M., Saalmuller A., Pfaff E. Immunomodulatory effect of plasmids co-expressing cytokines in classical swine fever virus subunit gp55/E2-DNA vaccination. Vet. Res. 2005, 36:571-587.
41. Xu R., Megati S., Roopchand V., Luckay A., Masood A., Garcia-Hand D., Rosati M., Weiner D.B., Felber B.K., Pavlakis G.N., Sidhu M.K., Eldridge J.H., Egan M.A. Comparative ability of various plasmid-based cytokines and chemokines to adjuvant the activity of HIV plasmid DNA vaccines. Vaccine 2008, 26:4819-4829.
42. Zanetti M., Castiglioni P., Rizzi M., Wheeler M., Gerloni M. B lymphocytes as antigen-presenting cell-based genetic vaccines. Immunol. Rev. 2004, 199:264-278.