A DNA vaccine expressing the E2 protein of classical swine fever virus elicits T cell responses that can prime for rapid antibody production and confer total protection upon viral challenge

Vaccine

Volumn 23, Issue 28, 2005, Pages 3741-3752

  Ganges, Llilianne ^a,b   Barrera, Maritza ^c   Núñez, José Ignacio ^a,b   Blanco, Isabel ^a   Frias, María Teresa ^c   Rodríguez, Fernando ^d   Sobrino, Francisco ^a,b  

^a Ctro de Invest en Sanidad Animal   (Spain)

^b CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^c CENSA   (Cuba)

^d CENTRE DE RECERCA EN SANITAT ANIMAL CRESA   (Spain)

Author keywords

CSFV; DNA immunization; Marker vaccine; T cell response

Indexed keywords

ANTIBODY; COMPLEMENTARY DNA; DNA VACCINE; E2 PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NEUTRALIZING ANTIBODY; PLASMID DNA; UNCLASSIFIED DRUG; VIRUS ANTIBODY; VIRUS VACCINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CELL STRAIN BHK; CONTROLLED STUDY; CORRELATION ANALYSIS; FEVER; HYPERTHERMIA; IMMUNIZATION; LEUKOPENIA; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PESTIVIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SWINE; SWINE DISEASE; SYMPTOM; T CELL DEPLETION; T LYMPHOCYTE; VIREMIA; VIRUS DETECTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, VIRAL; CELL PROLIFERATION; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; KIDNEY; LYMPH NODES; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; SPLEEN; SWINE; T-LYMPHOCYTES; VACCINES, DNA; VACCINES, MARKER; VIRAL ENVELOPE PROTEINS; VIRAL VACCINES; VIREMIA;

EID: 18844379112     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.01.153     Document Type: Article

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