Escape of classical swine fever C-strain vaccine virus from detection by C-strain specific real-time RT-PCR caused by a point mutation in the primer-binding site

Journal of Virological Methods

Volumn 166, Issue 1-2, 2010, Pages 98-100

  Leifer, Immanuel ^a   Everett, Helen ^b   Hoffmann, Bernd ^a   Sosan, Olubukola ^b   Crooke, Helen ^b   Beer, Martin ^a   Blome, Sandra ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

Author keywords

C strain vaccine; Classical swine fever; Genetic differentiation of infected from vaccinated animals; Real time RT PCR

Indexed keywords

VIRUS VACCINE;

ARTICLE; BINDING SITE; CLASSICAL SWINE FEVER; EPIDEMIC; GENE LOCATION; GENE SEQUENCE; GERMANY; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PESTIVIRUS; POINT MUTATION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SPECIES DIFFERENTIATION; STRAIN DIFFERENCE; VIRUS DETECTION; VIRUS STRAIN; WILD BOAR;

ANIMALS; BINDING SITES; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; DISEASE OUTBREAKS; DNA PRIMERS; GERMANY; POINT MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SENSITIVITY AND SPECIFICITY; SUS SCROFA; VIROLOGY;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 77952672868     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2010.03.004     Document Type: Article

References (6)

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