메뉴 건너뛰기




Volumn 31, Issue 7, 2011, Pages 843-847

Metastatic lymph node 51 and fibroblast-like synoviocyte hyperproliferation in rheumatoid arthritis pathogenesis

Author keywords

Fibroblast like synoviocyte; GM CSF; MLN51; Rheumatoid arthritis

Indexed keywords

FLICE INHIBITORY PROTEIN; METASTATIC LYMPH NODE 51 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

EID: 79960028726     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-011-1818-x     Document Type: Review
Times cited : (8)

References (50)
  • 1
    • 0035932519 scopus 로고    scopus 로고
    • Cytokine pathways and joint inflamation in rheumatoid arthritis
    • DOI 10.1056/NEJM200103223441207
    • EH Choy GS Panayi 2001 Cytokine pathways and joint inflammation in rheumatoid arthritis N Engl J Med 344 907 916 11259725 10.1056/ NEJM200103223441207 1:CAS:528:DC%2BD3MXisFyrur8%3D (Pubitemid 32224400)
    • (2001) New England Journal of Medicine , vol.344 , Issue.12 , pp. 907-916
    • Choy, E.H.S.1    Panayi, G.S.2
  • 2
    • 0029085746 scopus 로고
    • Cytokines in rheumatoid arthritis
    • 8846647 10.1007/BF02215851
    • FA Houssiau 1995 Cytokines in rheumatoid arthritis Clin Rheumatol 14 Suppl 2 10 13 8846647 10.1007/BF02215851
    • (1995) Clin Rheumatol , vol.14 , Issue.SUPPL. 2 , pp. 10-13
    • Houssiau, F.A.1
  • 3
    • 0023712236 scopus 로고
    • Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum
    • 3136775 10.1002/art.1780310816 1:STN:280:DyaL1czgvFWrsw%3D%3D
    • T Saxne MA Palladino Jr D Heinegard N Talal FA Wollheim 1988 Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum Arthritis Rheum 31 1041 1045 3136775 10.1002/art.1780310816 1:STN:280:DyaL1czgvFWrsw%3D%3D
    • (1988) Arthritis Rheum , vol.31 , pp. 1041-1045
    • Saxne, T.1    Palladino Jr., M.A.2    Heinegard, D.3    Talal, N.4    Wollheim, F.A.5
  • 4
    • 0028957263 scopus 로고
    • Peripheral blood and synovial fluid monocyte expression of interleukin 1 alpha and 1 beta during active rheumatoid arthritis
    • 7540690 1:STN:280:DyaK2MzhtFansQ%3D%3D
    • IC Chikanza G Kingsley GS Panayi 1995 Peripheral blood and synovial fluid monocyte expression of interleukin 1 alpha and 1 beta during active rheumatoid arthritis J Rheumatol 22 600 606 7540690 1:STN:280:DyaK2MzhtFansQ%3D%3D
    • (1995) J Rheumatol , vol.22 , pp. 600-606
    • Chikanza, I.C.1    Kingsley, G.2    Panayi, G.S.3
  • 5
    • 0024504366 scopus 로고
    • Characteristics of human synovial fibroblast activation by IL-1β and TNFα
    • BD Gitter JM Labus SL Lees ME Scheetz 1989 Characteristics of human synovial fibroblast activation by IL-1 beta and TNF alpha Immunology 66 196 200 2784408 1:CAS:528:DyaL1MXhslWntb0%3D (Pubitemid 19065793)
    • (1989) Immunology , vol.66 , Issue.2 , pp. 196-200
    • Gitter, B.D.1    Labus, J.M.2    Lees, S.L.3    Scheetz, M.E.4
  • 6
    • 0027375872 scopus 로고
    • The effects of cytokines on metalloproteinase inhibitors (TIMP) and collagenase production by human chondrocytes and TIMP production by synovial cells and endothelial cells
    • M Shingu Y Nagai T Isayama T Naono M Nobunaga 1993 The effects of cytokines on metalloproteinase inhibitors (TIMP) and collagenase production by human chondrocytes and TIMP production by synovial cells and endothelial cells Clin Exp Immunol 94 145 149 8403497 10.1111/j.1365-2249.1993.tb05992.x 1:CAS:528:DyaK3sXms1yltb8%3D (Pubitemid 23308380)
    • (1993) Clinical and Experimental Immunology , vol.94 , Issue.1 , pp. 145-149
    • Shingu, M.1    Nagai, Y.2    Isayama, T.3    Naono, T.4    Nobunaga, M.5    Nagai, Y.6
  • 8
    • 0035555275 scopus 로고    scopus 로고
    • Pathogenesis of arthritis: Recent research progress
    • 11526382 10.1038/ni0901-771 1:STN:280:DC%2BD3MvotlWjsA%3D%3D
    • M Feldmann 2001 Pathogenesis of arthritis: recent research progress Nat Immunol 2 771 773 11526382 10.1038/ni0901-771 1:STN:280:DC%2BD3MvotlWjsA%3D%3D
    • (2001) Nat Immunol , vol.2 , pp. 771-773
    • Feldmann, M.1
  • 10
    • 0029925484 scopus 로고    scopus 로고
    • Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4
    • DOI 10.1002/art.1780390516
    • JA van Roon JL van Roy FH Gmelig-Meyling FP Lafeber JW Bijlsma 1996 Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4 Arthritis Rheum 39 829 835 8639180 10.1002/art.1780390516 (Pubitemid 26140429)
    • (1996) Arthritis and Rheumatism , vol.39 , Issue.5 , pp. 829-835
    • Van Roon, J.A.G.1    Van Roy, J.L.A.M.2    Gmelig-Meyling, F.H.J.3    Lafeber, F.P.J.G.4    Bijlsma, J.W.J.5
  • 11
    • 0028827513 scopus 로고
    • Interleukin 10 cooperates with interleukin 4 to suppress inflammatory cytokine production by freshly prepared adherent rheumatoid synovial cells
    • 8596138 1:CAS:528:DyaK28XotVSj
    • E Sugiyama A Kuroda H Taki M Ikemoto T Hori N Yamashita M Maruyama M Kobayashi 1995 Interleukin 10 cooperates with interleukin 4 to suppress inflammatory cytokine production by freshly prepared adherent rheumatoid synovial cells J Rheumatol 22 2020 2026 8596138 1:CAS:528:DyaK28XotVSj
    • (1995) J Rheumatol , vol.22 , pp. 2020-2026
    • Sugiyama, E.1    Kuroda, A.2    Taki, H.3    Ikemoto, M.4    Hori, T.5    Yamashita, N.6    Maruyama, M.7    Kobayashi, M.8
  • 12
    • 0031201054 scopus 로고    scopus 로고
    • Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation
    • 9250144 1:CAS:528:DyaK2sXls1Wnu7Y%3D
    • RS Smith TJ Smith TM Blieden RP Phipps 1997 Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation Am J Pathol 151 317 322 9250144 1:CAS:528:DyaK2sXls1Wnu7Y%3D
    • (1997) Am J Pathol , vol.151 , pp. 317-322
    • Smith, R.S.1    Smith, T.J.2    Blieden, T.M.3    Phipps, R.P.4
  • 13
    • 0034469496 scopus 로고    scopus 로고
    • Fibroblast biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis
    • DOI 10.1186/ar113
    • T Pap U Muller-Ladner RE Gay S Gay 2000 Fibroblast biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis Arthritis Res 2 361 367 11094449 10.1186/ar113 1:CAS:528:DC%2BD3cXmtVejsrg%3D (Pubitemid 32223765)
    • (2000) Arthritis Research , vol.2 , Issue.5 , pp. 361-367
    • Pap, T.1    Muller-Ladner, U.2    Gay, R.E.3    Gay, S.4
  • 14
    • 0000923770 scopus 로고    scopus 로고
    • Angiogenesis in arthritis: Role in disease pathogenesis and as a potential therapeutic target
    • EM Paleolog JM Miotla 1998 Angiogenesis in arthritis: role in disease pathogenesis and as a potential therapeutic target Angiogenesis 2 295 307 14517450 10.1023/A:1009229508096 1:STN:280:DC%2BD3svlsFajsg%3D%3D (Pubitemid 128514257)
    • (1998) Angiogenesis , vol.2 , Issue.4 , pp. 295-307
    • Paleolog, E.M.1    Miotla, J.M.2
  • 15
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • DOI 10.1038/nature01661
    • GS Firestein 2003 Evolving concepts of rheumatoid arthritis Nature 423 356 361 12748655 10.1038/nature01661 1:CAS:528:DC%2BD3sXjs1ynu7c%3D (Pubitemid 40852711)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 356-361
    • Firestein, G.S.1
  • 16
    • 34250182412 scopus 로고    scopus 로고
    • Matrix metalloproteinases and cartilage matrix degradation in rheumatoid arthritis
    • 17404478 1:CAS:528:DC%2BD2sXlvFKgsr0%3D
    • Y Yoshihara H Yamada 2007 Matrix metalloproteinases and cartilage matrix degradation in rheumatoid arthritis Clin Calcium 17 500 508 17404478 1:CAS:528:DC%2BD2sXlvFKgsr0%3D
    • (2007) Clin Calcium , vol.17 , pp. 500-508
    • Yoshihara, Y.1    Yamada, H.2
  • 17
    • 48549096292 scopus 로고    scopus 로고
    • Role of cysteine cathepsins in matrix degradation and cell signalling
    • 18661341 10.1080/03008200802143158 1:CAS:528:DC%2BD1cXptVKlsbs%3D
    • N Obermajer Z Jevnikar B Doljak J Kos 2008 Role of cysteine cathepsins in matrix degradation and cell signalling Connect Tissue Res 49 193 196 18661341 10.1080/03008200802143158 1:CAS:528:DC%2BD1cXptVKlsbs%3D
    • (2008) Connect Tissue Res , vol.49 , pp. 193-196
    • Obermajer, N.1    Jevnikar, Z.2    Doljak, B.3    Kos, J.4
  • 18
    • 0642286559 scopus 로고    scopus 로고
    • Rheumatoid arthritis: Targeting the proliferative fibroblasts
    • 14593701
    • I Kramer A Wibulswas D Croft E Genot 2003 Rheumatoid arthritis: targeting the proliferative fibroblasts Prog Cell Cycle Res 5 59 70 14593701
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 59-70
    • Kramer, I.1    Wibulswas, A.2    Croft, D.3    Genot, E.4
  • 19
    • 0037182754 scopus 로고    scopus 로고
    • Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer
    • DOI 10.1038/sj.onc.1205611
    • S Degot CH Regnier C Wendling MP Chenard MC Rio C Tomasetto 2002 Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer Oncogene 21 4422 4434 12080473 10.1038/sj.onc.1205611 1:CAS:528:DC%2BD38XkslKntLY%3D (Pubitemid 34774845)
    • (2002) Oncogene , vol.21 , Issue.28 , pp. 4422-4434
    • Degot, S.1    Regnier, C.H.2    Wendling, C.3    Chenard, M.-P.4    Rio, M.-C.5    Tomasetto, C.6
  • 20
    • 34648866440 scopus 로고    scopus 로고
    • MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis
    • 17101062 10.1186/ar2079
    • J Jang DS Lim YE Choi Y Jeong SA Yoo WU Kim YS Bae 2006 MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis Arthritis Res Ther 8 R170 17101062 10.1186/ar2079
    • (2006) Arthritis Res Ther , vol.8 , pp. 170
    • Jang, J.1    Lim, D.S.2    Choi, Y.E.3    Jeong, Y.4    Yoo, S.A.5    Kim, W.U.6    Bae, Y.S.7
  • 22
    • 4043118349 scopus 로고    scopus 로고
    • Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module
    • DOI 10.1074/jbc.M402754200
    • S Degot H Le Hir F Alpy V Kedinger I Stoll C Wendling B Seraphin MC Rio C Tomasetto 2004 Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module J Biol Chem 279 33702 33715 15166247 10.1074/jbc.M402754200 1:CAS:528:DC%2BD2cXmtFOiurY%3D (Pubitemid 39063020)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.32 , pp. 33702-33715
    • Degot, S.1    Le Hir, H.2    Alpy, F.3    Kedinger, V.4    Stoll, I.5    Wendling, C.6    Seraphin, B.7    Rio, M.-C.8    Tomasetto, C.9
  • 23
    • 28344456363 scopus 로고    scopus 로고
    • Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core
    • DOI 10.1261/rna.2155905
    • TO Tange T Shibuya MS Jurica MJ Moore 2005 Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core RNA 11 1869 1883 16314458 10.1261/rna.2155905 1:CAS:528:DC%2BD2MXhtlWnu7rO (Pubitemid 41720036)
    • (2005) RNA , vol.11 , Issue.12 , pp. 1869-1883
    • Tange, T.O.1    Shibuya, T.2    Jurica, M.S.3    Moore, M.J.4
  • 24
    • 0036512117 scopus 로고    scopus 로고
    • Messenger-RNA-binding proteins and the messages they carry
    • 11994740 10.1038/nrm760 1:CAS:528:DC%2BD38XitFShsLo%3D
    • G Dreyfuss VN Kim N Kataoka 2002 Messenger-RNA-binding proteins and the messages they carry Nat Rev Mol Cell Biol 3 195 205 11994740 10.1038/nrm760 1:CAS:528:DC%2BD38XitFShsLo%3D
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 195-205
    • Dreyfuss, G.1    Kim, V.N.2    Kataoka, N.3
  • 26
    • 0029149178 scopus 로고
    • Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17
    • 7490069 10.1006/geno.1995.1163 1:CAS:528:DyaK2MXnslahsrg%3D
    • C Tomasetto C Regnier C Moog-Lutz MG Mattei MP Chenard R Lidereau P Basset MC Rio 1995 Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17 Genomics 28 367 376 7490069 10.1006/geno.1995.1163 1:CAS:528:DyaK2MXnslahsrg%3D
    • (1995) Genomics , vol.28 , pp. 367-376
    • Tomasetto, C.1    Regnier, C.2    Moog-Lutz, C.3    Mattei, M.G.4    Chenard, M.P.5    Lidereau, R.6    Basset, P.7    Rio, M.C.8
  • 27
    • 50549086534 scopus 로고    scopus 로고
    • FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis
    • 18513326 10.1111/j.1742-4658.2008.06500.x 1:CAS:528:DC%2BD1cXovVSmtLc%3D
    • JE Ha YE Choi J Jang CH Yoon HY Kim YS Bae 2008 FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis FEBS J 275 3546 3555 18513326 10.1111/j.1742-4658.2008.06500.x 1:CAS:528:DC%2BD1cXovVSmtLc%3D
    • (2008) FEBS J , vol.275 , pp. 3546-3555
    • Ha, J.E.1    Choi, Y.E.2    Jang, J.3    Yoon, C.H.4    Kim, H.Y.5    Bae, Y.S.6
  • 28
    • 0035018695 scopus 로고    scopus 로고
    • Pathogenesis of rheumatoid arthritis: The role of synoviocytes
    • Y Yamanishi GS Firestein 2001 Pathogenesis of rheumatoid arthritis: the role of synoviocytes Rheum Dis Clin North Am 27 355 371 11396097 10.1016/S0889-857X(05)70206-4 1:STN:280:DC%2BD3MzivVKntg%3D%3D (Pubitemid 32488710)
    • (2001) Rheumatic Disease Clinics of North America , vol.27 , Issue.2 , pp. 355-371
    • Yamanishi, Y.1    Firestein, G.S.2
  • 29
    • 0036720825 scopus 로고    scopus 로고
    • Identification of the genes differentially expressed in human dendritic cell subsets by cDNA subtraction and microarray analysis
    • JH Ahn Y Lee C Jeon SJ Lee BH Lee KD Choi YS Bae 2002 Identification of the genes differentially expressed in human dendritic cell subsets by cDNA subtraction and microarray analysis Blood 100 1742 1754 12176896 1:CAS:528:DC%2BD38Xmslyht7Y%3D (Pubitemid 34925153)
    • (2002) Blood , vol.100 , Issue.5 , pp. 1742-1754
    • Ahn, J.H.1    Lee, Y.2    Jeon, C.3    Lee, S.-J.4    Lee, B.-H.5    Choi, K.D.6    Bae, Y.-S.7
  • 30
    • 0027401966 scopus 로고
    • A model for the interaction of the GM-CSF, IL-3 and IL-5 receptors with their ligands
    • GJ Goodall CJ Bagley MA Vadas AF Lopez 1993 A model for the interaction of the GM-CSF, IL-3 and IL-5 receptors with their ligands Growth Factors 8 87 97 8466757 10.3109/08977199309046929 1:STN:280:DyaK3s3itFymtQ%3D%3D (Pubitemid 23082904)
    • (1993) Growth Factors , vol.8 , Issue.2 , pp. 87-97
    • Goodall, G.J.1    Bagley, C.J.2    Vadas, M.A.3    Lopez, A.F.4
  • 31
    • 0036201268 scopus 로고    scopus 로고
    • GM-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense
    • DOI 10.1146/annurev.physiol.64.090601.113847
    • BC Trapnell JA Whitsett 2002 Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense Annu Rev Physiol 64 775 802 11826288 10.1146/annurev.physiol.64.090601.113847 1:CAS:528:DC%2BD38XisFGmtrw%3D (Pubitemid 34259249)
    • (2002) Annual Review of Physiology , vol.64 , pp. 775-802
    • Trapnell, B.C.1    Whitsett, J.A.2
  • 32
    • 0024846310 scopus 로고
    • Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor
    • DP Gearing JA King NM Gough NA Nicola 1989 Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor EMBO J 8 3667 3676 2555171 1:CAS:528:DyaK3cXhvFaqsLk%3D (Pubitemid 20016045)
    • (1989) EMBO Journal , vol.8 , Issue.12 , pp. 3667-3676
    • Gearing, D.P.1    King, J.A.2    Gough, N.M.3    Nicola, N.A.4
  • 34
    • 0028180569 scopus 로고
    • JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region
    • 8007942 1:CAS:528:DyaK2cXksFSkt78%3D
    • FW Quelle N Sato BA Witthuhn RC Inhorn M Eder A Miyajima JD Griffin JN Ihle 1994 JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region Mol Cell Biol 14 4335 4341 8007942 1:CAS:528:DyaK2cXksFSkt78%3D
    • (1994) Mol Cell Biol , vol.14 , pp. 4335-4341
    • Quelle, F.W.1    Sato, N.2    Witthuhn, B.A.3    Inhorn, R.C.4    Eder, M.5    Miyajima, A.6    Griffin, J.D.7    Ihle, J.N.8
  • 35
    • 0030794017 scopus 로고    scopus 로고
    • The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor α subunit is essential for both GM-CSF-mediated growth and differentiation
    • DOI 10.1074/jbc.272.28.17450
    • T Matsuguchi Y Zhao MB Lilly AS Kraft 1997 The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation J Biol Chem 272 17450 17459 9211889 10.1074/jbc.272.28.17450 1:CAS:528:DyaK2sXksFOru7Y%3D (Pubitemid 27311176)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.28 , pp. 17450-17459
    • Matsuguchi, T.1    Zhao, Y.2    Lilly, M.B.3    Kraft, A.S.4
  • 36
    • 0026808525 scopus 로고
    • Tyrosine phosphorylation of receptor beta subunits and common substrates in response to interleukin-3 and granulocyte-macrophage colony-stimulating factor
    • 1400495 1:CAS:528:DyaK38Xls12hsbo%3D
    • V Duronio I Clark-Lewis B Federsppiel JS Wieler JW Schrader 1992 Tyrosine phosphorylation of receptor beta subunits and common substrates in response to interleukin-3 and granulocyte-macrophage colony-stimulating factor J Biol Chem 267 21856 21863 1400495 1:CAS:528:DyaK38Xls12hsbo%3D
    • (1992) J Biol Chem , vol.267 , pp. 21856-21863
    • Duronio, V.1    Clark-Lewis, I.2    Federsppiel, B.3    Wieler, J.S.4    Schrader, J.W.5
  • 37
    • 0026733625 scopus 로고
    • Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation
    • 1396555 1:CAS:528:DyaK3sXltlOn
    • K Sakamaki I Miyajima T Kitamura A Miyajima 1992 Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation EMBO J 11 3541 3549 1396555 1:CAS:528:DyaK3sXltlOn
    • (1992) EMBO J , vol.11 , pp. 3541-3549
    • Sakamaki, K.1    Miyajima, I.2    Kitamura, T.3    Miyajima, A.4
  • 38
    • 0030446865 scopus 로고    scopus 로고
    • Roles of JAK kinases in human GM-CSF receptor signal transduction
    • DOI 10.1016/S0091-6749(96)70065-9
    • S Watanabe T Itoh K Arai 1996 Roles of JAK kinases in human GM-CSF receptor signal transduction J Allergy Clin Immunol 98 S183 S191 8977526 10.1016/S0091-6749(96)70065-9 1:CAS:528:DyaK2sXkslWruw%3D%3D (Pubitemid 27016472)
    • (1996) Journal of Allergy and Clinical Immunology , vol.98 , Issue.6
    • Watababe, S.1    Itoh, T.2    Arai, K.-I.3
  • 39
    • 0033672653 scopus 로고    scopus 로고
    • Abnormal stat activation, hematopoietic homeostasis, and innate immunity in c-fes-/- mice
    • 11021537 10.1016/S1074-7613(00)00039-X 1:CAS:528:DC%2BD3cXntlCmt78%3D
    • R Hackenmiller J Kim RA Feldman MC Simon 2000 Abnormal stat activation, hematopoietic homeostasis, and innate immunity in c-fes-/- mice Immunity 13 397 407 11021537 10.1016/S1074-7613(00)00039-X 1:CAS:528:DC%2BD3cXntlCmt78%3D
    • (2000) Immunity , vol.13 , pp. 397-407
    • Hackenmiller, R.1    Kim, J.2    Feldman, R.A.3    Simon, M.C.4
  • 40
    • 15444370901 scopus 로고    scopus 로고
    • Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes
    • T Inoue D Hammaker DL Boyle GS Firestein 2005 Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes J Immunol 174 4301 4306 15778394 1:CAS:528:DC%2BD2MXisVChtrc%3D (Pubitemid 40396012)
    • (2005) Journal of Immunology , vol.174 , Issue.7 , pp. 4301-4306
    • Inoue, T.1    Hammaker, D.2    Boyle, D.L.3    Firestein, G.S.4
  • 41
    • 0033758633 scopus 로고    scopus 로고
    • Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis
    • 11083274 10.1002/1529-0131(200011)43:11<2501::AID-ANR18>3.0.CO;2-K 1:CAS:528:DC%2BD3cXosFyntbk%3D
    • G Schett M Tohidast-Akrad JS Smolen BJ Schmid CW Steiner P Bitzan P Zenz K Redlich Q Xu G Steiner 2000 Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis Arthritis Rheum 43 2501 2512 11083274 10.1002/1529-0131(200011)43:11<2501::AID- ANR18>3.0.CO;2-K 1:CAS:528:DC%2BD3cXosFyntbk%3D
    • (2000) Arthritis Rheum , vol.43 , pp. 2501-2512
    • Schett, G.1    Tohidast-Akrad, M.2    Smolen, J.S.3    Schmid, B.J.4    Steiner, C.W.5    Bitzan, P.6    Zenz, P.7    Redlich, K.8    Xu, Q.9    Steiner, G.10
  • 43
    • 0142072322 scopus 로고    scopus 로고
    • Bone Morphogenetic Proteins 2 and 6, Expressed in Arthritic Synovium, are Regulated by Proinflammatory Cytokines and Differentially Modulate Fibroblast-Like Synoviocyte Apoptosis
    • DOI 10.1002/art.11389
    • RJ Lories I Derese JL Ceuppens FP Luyten 2003 Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis Arthritis Rheum 48 2807 2818 14558086 10.1002/art.11389 1:CAS:528: DC%2BD3sXpt1Srsrw%3D (Pubitemid 37280609)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.10 , pp. 2807-2818
    • Lories, R.J.U.1    Derese, I.2    Ceuppens, J.L.3    Luyten, F.P.4
  • 44
    • 4444292431 scopus 로고    scopus 로고
    • Down-regulation of FLIP sensitizes rheumatoid synovial fibroblasts to Fas-mediated apoptosis
    • DOI 10.1002/art.20453
    • G Palao B Santiago M Galindo M Paya JC Ramirez JL Pablos 2004 Down-regulation of FLIP sensitizes rheumatoid synovial fibroblasts to Fas-mediated apoptosis Arthritis Rheum 50 2803 2810 15457448 10.1002/art.20453 1:CAS:528:DC%2BD2cXoslGgsL4%3D (Pubitemid 39209517)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.9 , pp. 2803-2810
    • Palao, G.1    Santiago, B.2    Galindo, M.3    Paya, M.4    Ramirez, J.C.5    Pablos, J.L.6
  • 45
    • 39049148397 scopus 로고    scopus 로고
    • Cellular FLICE-like inhibitory protein (C-FLIP): A novel target for cancer therapy
    • DOI 10.2174/156800908783497087
    • AR Safa TW Day CH Wu 2008 Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy Curr Cancer Drug Targets 8 37 46 18288942 10.2174/156800908783497087 1:CAS:528:DC%2BD1cXitF2ku7Y%3D (Pubitemid 351237908)
    • (2008) Current Cancer Drug Targets , vol.8 , Issue.1 , pp. 37-46
    • Safa, A.R.1    Day, T.W.2    Wu, C.-H.3
  • 46
    • 19544382901 scopus 로고    scopus 로고
    • The caspase-8 modulator c-FLIP
    • DOI 10.1615/CritRevImmunol.v25.i1.30
    • T Kataoka 2005 The caspase-8 modulator c-FLIP Crit Rev Immunol 25 31 58 15833082 10.1615/CritRevImmunol.v25.i1.30 1:CAS:528:DC%2BD2MXktlajs7c%3D (Pubitemid 40733355)
    • (2005) Critical Reviews in Immunology , vol.25 , Issue.1 , pp. 31-58
    • Kataoka, T.1
  • 48
    • 0034648529 scopus 로고    scopus 로고
    • Activation of the NF-kappaB pathway by caspase 8 and its homologs
    • 11002417 10.1038/sj.onc.1203812 1:CAS:528:DC%2BD3cXntlGntbY%3D
    • PM Chaudhary MT Eby A Jasmin A Kumar L Liu L Hood 2000 Activation of the NF-kappaB pathway by caspase 8 and its homologs Oncogene 19 4451 4460 11002417 10.1038/sj.onc.1203812 1:CAS:528:DC%2BD3cXntlGntbY%3D
    • (2000) Oncogene , vol.19 , pp. 4451-4460
    • Chaudhary, P.M.1    Eby, M.T.2    Jasmin, A.3    Kumar, A.4    Liu, L.5    Hood, L.6
  • 49
    • 8744297444 scopus 로고    scopus 로고
    • Fas ligand induces cell-autonomous NF-κB activation and interleukin-8 production by a mechanism distinct from that of tumor necrosis factor-α
    • DOI 10.1074/jbc.M403226200
    • R Imamura K Konaka N Matsumoto M Hasegawa M Fukui N Mukaida T Kinoshita T Suda 2004 Fas ligand induces cell-autonomous NF-kappaB activation and interleukin-8 production by a mechanism distinct from that of tumor necrosis factor-alpha J Biol Chem 279 46415 46423 15337758 10.1074/jbc.M403226200 1:CAS:528:DC%2BD2cXptFaqtrY%3D (Pubitemid 39518283)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.45 , pp. 46415-46423
    • Imamura, R.1    Konaka, K.2    Matsumoto, N.3    Hasegawa, M.4    Fukui, M.5    Mukaida, N.6    Kinoshita, T.7    Suda, T.8
  • 50
    • 0032431998 scopus 로고    scopus 로고
    • Establishment and characterization of a novel human rheumatoid fibroblast-like synoviocyte line, MH7A, immortalized with SV40 T antigen
    • K Miyazawa A Mori H Okudaira 1998 Establishment and characterization of a novel human rheumatoid fibroblast-like synoviocyte line, MH7A, immortalized with SV40 T antigen J Biochem 124 1153 1162 9832620 1:CAS:528: DyaK1MXnsVSisQ%3D%3D (Pubitemid 29017304)
    • (1998) Journal of Biochemistry , vol.124 , Issue.6 , pp. 1153-1162
    • Miyazawa, K.1    Mori, A.2    Okudaira, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.