Oral administration of the thrombin receptor antagonist E5555 (atopaxar) attenuates intimal thickening following balloon injury in rats

European Journal of Pharmacology

Volumn 666, Issue 1-3, 2011, Pages 158-164

  Kogushi, Motoji ^a   Matsuoka, Toshiyuki ^a   Kuramochi, Hiroko ^a   Murakami, Kimiyo ^a   Kawata, Tsutomu ^a   Kimura, Akifumi ^a   Chiba, Kenichi ^a   Musha, Takashi ^a   Suzuki, Shuichi ^a   Kawahara, Tetsuya ^a   Kajiwara, Akiharu ^a   Hishinuma, Ieharu ^a  

^a EISAI CO LTD   (Japan)

Author keywords

Atopaxar; E5555; PAR 1 antagonist; Proliferation; Restenosis; Smooth muscle cell

Indexed keywords

ATOPAXAR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA MEDIA; ARTERY INTIMA PROLIFERATION; ARTICLE; CAROTID ARTERY INJURY; CELL PROLIFERATION; CONCENTRATION RESPONSE; DRUG EFFECT; DRUG SELECTIVITY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER;

ADMINISTRATION, ORAL; ANGIOPLASTY, BALLOON; ANIMALS; BLEEDING TIME; BLOOD COAGULATION; CELL PROLIFERATION; HUMANS; IMINES; MALE; MYOCYTES, SMOOTH MUSCLE; NEOINTIMA; PLATELET AGGREGATION; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, THROMBIN; THROMBIN; TIME FACTORS; TUNICA INTIMA;

EID: 79959999841     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.05.034     Document Type: Article

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