Noradrenergic regulation of itch transmission in the spinal cord mediated by α-adrenoceptors

Neuropharmacology

Volumn 61, Issue 4, 2011, Pages 825-831

  Gotoh, Yoshikazu ^a   Andoh, Tsugunobu ^a   Kuraishi, Yasushi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Adrenoceptor; Biting; Descending noradrenergic system; Itch; Spinal cord

Indexed keywords

5 METHYLURAPIDIL; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 2A ADRENERGIC RECEPTOR; ALPHA 2B ADRENERGIC RECEPTOR; ALPHA 2C ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CLONIDINE; CYCLAZOCINE; DOPAMINE; MESSENGER RNA; NORADRENALIN; OXIDOPAMINE; PHENTOLAMINE; PHENYLEPHRINE; PRAZOSIN; SEROTONIN; YOHIMBINE;

ADRENERGIC TRANSMISSION; ALPHA ADRENERGIC RECEPTOR BLOCKING; ALPHA ADRENERGIC STIMULATION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG DOSE COMPARISON; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PRURITUS; SPINAL CORD; SPINAL CORD DORSAL HORN; SPINAL GANGLION;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; INJECTIONS, SPINAL; MALE; MICE; MICE, INBRED ICR; NOREPINEPHRINE; OXIDOPAMINE; PRURITUS; RECEPTORS, ADRENERGIC, ALPHA; SEROTONIN; SPINAL CORD;

EID: 79959997059     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.05.030     Document Type: Article

References (63)

1. T. Akiyama, M.I. Carstens, and E. Carstens Differential itch- and pain-related behavioral responses and μ-opoid modulation in mice Acta Derm. Venereol. 90 2010 575 581
2. T. Akiyama, M.I. Carstens, and E. Carstens Facial injections of pruritogens and algogens excite partly overlapping populations of primary and second-order trigeminal neurons in mice J. Neurophysiol. 104 2010 2442 2450
3. 2, induces itch-associated responses in mice Eur. J. Pharmacol. 353 1998 93 96 (Pubitemid 28352294)
4. T. Andoh, and Y. Kuraishi Nitric oxide enhances substance P-induced itch-associated responses in mice Br. J. Pharmacol. 138 2003 202 208 (Pubitemid 36194221)
5. 1 tachykinin receptors in mice J. Pharmacol. Exp. Ther. 286 1998 1140 1145 (Pubitemid 29135521)
6. 4 mediates sphingosylphosphoryl-choline-induced itch-associated responses in mouse skin J. Invest. Dermatol. 129 2009 2854 2860
7. 4 in mice J. Invest. Dermatol. 123 2004 196 201 (Pubitemid 38833481)
8. H. Baba, K. Shimoji, and M. Yoshimura Norepinephrine facilitates inhibitory transmission in substantia gelatinosa of adult rat spinal cord (part 1): effects on axon terminals of GABAergic and glycinergic neurons Anesthesiology 92 2000 473 484 (Pubitemid 30078346)
9. H. Baba, P.A. Goldstein, M. Okamoto, T. Kohno, T. Ataka, M. Yoshimura, and K. Shimoji Norepinephrine facilitates inhibitory transmission in substantia gelatinosa of adult rat spinal cord (part 2): effects on somatodendritic sites of GABAergic neurons Anesthesiology 92 2000 485 492 (Pubitemid 30078347)
10. N.V. Bergasa, D.W. Alling, T.L. Talbot, M.G. Swain, C. Yurdaydin, M.L. Turner, J.M. Schmitt, E.C. Walker, and E.A. Jones Effects of naloxone infusions in patients with the pruritus of cholestasis. A double-blind, randomized, controlled trial Ann. Intern. Med. 123 1995 161 167
11. J.E. Bernstein, R.M. Swift, K. Soltani, and A.L. Lorincz Antipruritic effect of an opiate antagonist, naloxone hydrochloride J. Invest. Dermatol. 78 1982 82 83 (Pubitemid 12207162)
12. D.B. Bylund, D.C. Eikenberg, J.P. Hieble, S.Z. Langer, R.J. Lefkowitz, K.P. Minneman, P.B. Molinoff, R.R. Ruffolo, and U. Trendelenburg International union of pharmacology nomenclature of adrenoceptors Pharmacol. Rev. 46 1994 121 136
13. E. Carstens Responses of rat spinal dorsal horn neurons to intracutaneous microinjection of histamine, capsaicin, and other irritants J. Neurophysiol. 77 1997 2499 2514 (Pubitemid 27209218)
14. S. Davidson, X. Zhang, C.H. Yoon, S.G. Khasabov, D.A. Simone, and G.J. Giesler Jr. The itch-producing agents histamine and cowhage activate separate populations of primate spinothalamic tract neurons J. Neurosci. 27 2007 10007 10014 (Pubitemid 47404005)
15. M.A. Elkersh, T.T. Simopoulos, A.B. Malik, E.H. Cho, and Z.H. Bajwa Epidural clonidine relieves intractable neuropathic itch associated with herpes zoster-related pain Reg. Anesth. Pain Med. 28 2003 344 346 (Pubitemid 36936260)
16. 1- adrenoceptor classification Br. J. Pharmacol. 121 1997 1127 1135 (Pubitemid 27303581)
17. M. Gassner, R. Ruscheweyh, and J. Sandkühler Direct excitation of spinal GABAergic interneurons by noradrenaline Pain 145 2009 204 210
18. D. Giardina, M. Crucianelli, R. Romanelli, A. Leonardi, E. Poggesi, and C. Melchiorre Synthesis and biological profile of the enantiomers of [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)- cis-octahydroquinoxalin-1-yl]furan-2- ylmethanone (cyclazosin) a potent competitive alpha-1B adrenoceptor antagonist J. Med. Chem. 39 1996 4602 4607 (Pubitemid 26382845)
19. 2-Adrenergic receptor subtypes in rat dorsal root and superior cervical ganglion neurons Pain 69 1997 179 190 (Pubitemid 27081424)
20. 2-adrenoceptors in the spinal cord in mice Eur. J. Pharmacol. 650 2011 215 219
21. Y. Gotoh, Y. Omori, T. Andoh, and Y. Kuraishi Tonic inhibition of allergic itch signaling by the descending noradrenergic system in mice J. Pharmacol. Sci. 115 2011 417 420
22. K. Hagiwara, H. Nojima, and Y. Kuraishi Serotonin-induced biting of the hind paw is itch-related response in mice Pain Res. 14 1999 53 59
23. M.B. Hussain, and I. Marshall Characterization of alpha1-adrenoceptor subtypes mediating contractions to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery Br. J. Pharmacol. 122 1997 849 858 (Pubitemid 27460166)
24. J.L. Hylden, and G.L. Wilcox Intrathecal morphine in mice: a new technique Eur. J. Pharmacol. 67 1980 313 316 (Pubitemid 10007057)
25. 3H]-guanfacine: a radioligand that selectively labels high affinity α2-adrenoceptor sites in homogenates of rat brain Br. J. Pharmacol. 75 1982 401 408 (Pubitemid 12213570)
26. L.M. Johanek, R.A. Meyer, T. Hartke, J.G. Hobelmann, D.N. Maine, R.H. LaMotte, and M. Ringkamp Psychophysical and physiological evidence for parallel afferent pathways mediating the sensation of itch J. Neurosci. 27 2007 7490 7497 (Pubitemid 47066576)
27. Y. Kuraishi, N. Hirota, Y. Sato, S. Kaneko, M. Satoh, and H. Takagi Noradrenergic inhibition of the release of substance P from the primary afferents in the rabbit spinal dorsal horn Brain Res. 359 1985 177 182 (Pubitemid 16185330)
28. Y. Kuraishi, T. Nagasawa, K. Hayashi, and M. Satoh Scratching behavior induced by pruritogenic but algesiogenic agents in mice Eur. J. Pharmacol. 275 1995 229 233
29. Y. Kuraishi, E. Ohtsuka, T. Nakano, S. Kawai, T. Andoh, H. Nojima, and K. Kamimura Possible involvement of 5-lipoxygenase metabolite in itch-associated response of mosquito allergy in mice J. Pharmacol. Sci. 105 2007 41 47 (Pubitemid 47463523)
30. Y. Kuraishi, Y. Yageta, M. Konno, T. Andoh, T. Yamaguchi-Miyamoto, and H. Nojima Intracisternal, but not intrathecal, injection of naloxone inhibits cutaneous itch-related response in mice Biol. Pharm. Bull. 31 2008 2143 2145
31. 2A-Adrenoceptor stimulation reduces capsaicin-induced glutamate release from spinal cord synaptosomes J. Pharmacol. Exp. Ther. 299 2001 939 944 (Pubitemid 33104963)
32. T. Maekawa, H. Nojima, and Y. Kuraishi Itch-associated responses of afferent nerve innervating the murine skin: different effects of histamine and serotonin in ICR and ddY mice Jpn. J. Pharmacol. 84 2000 462 466 (Pubitemid 32043740)
33. T. Maekawa, T. Yamaguchi-Miyamoto, H. Nojima, and Y. Kuraishi Effects of naltrexone on spontaneous itch-associated responses in NC mice with chronic dermatitis Jpn. J. Pharmacol. 90 2002 193 196 (Pubitemid 35291306)
34. M.J. Millan Descending control of pain Prog. Neurobiol. 66 2002 355 474 (Pubitemid 34606906)
35. 2-adrenoceptors. Part I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine J. Pharmacol. Exp. Ther. 295 2000 1192 1205
36. T. Miyamoto, H. Nojima, T. Shinkado, T. Nakahashi, and Y. Kuraishi Itch-associated response induced by experimental dry skin in mice Jpn. J. Pharmacol. 88 2002 285 292 (Pubitemid 34302979)
37. H. Mochizuki, M. Tashiro, M. Kano, Y. Sakurada, M. Itoh, and K. Yanai Imaging of central itch modulation in the human brain using positron emission tomography Pain 105 2003 339 346 (Pubitemid 37162504)
38. E.W. Monroe Efficacy and safety of nalmefene in patients with severe pruritis caused by chronic urticaria and atopic dermatitis J. Am. Acad. Dermatol. 21 1989 135 136 (Pubitemid 19171479)
39. T. Nakano, T. Andoh, J.B. Lee, and Y. Kuraishi Different dorsal horn neurons responding to histamine and allergic itch stimuli Neuroreport 19 2008 723 726 (Pubitemid 351555989)
40. T. Nakano, T. Andoh, M. Tayama, M. Kosaka, J.B. Lee, and Y. Kuraishi Effects of topical application of tacrolimus on acute itch-associated responses in mice Biol. Pharm. Bull. 31 2008 752 754 (Pubitemid 351500498)
41. T. Nakazawa, Y. Yamanishi, and T. Kaneko A comparative study of monoaminergic involvement in the antinociceptive action of E-2078, morphine and U-50,488E J. Pharmacol. Exp. Ther. 257 1991 748 753
42. R. Nicholson, A.K. Dixon, D. Spanswick, and K. Lee Noradrenergic receptor mRNA expression in adult rat superficial dorsal horn and dorsal root ganglion neurons Neurosci. Lett. 380 2005 316 321 (Pubitemid 40616103)
43. H. Nojima, C.T. Simons, J.M. Cuellar, M.I. Carstens, J.A. Moore, and E. Carstens Opioid modulation of scratching and spinal c-fos expression evoked by intradermal serotonin J. Neurosci. 23 2003 10784 10790 (Pubitemid 37499684)
44. E. Ohtsuka, S. Kawai, T. Ichikawa, H. Nojima, K. Kitagawa, Y. Shirai, K. Kamimura, and Y. Kuraishi Roles of mast cells and histamine in mosquito bite-induced allergic itch-associated responses in mice Jpn. J. Pharmacol. 86 2001 97 105
45. A. Parini, I. Coupry, R.M. Graham, I. Uzielli, D. Atlas, and S.M. Lanier Characterization of an imidazoline/guanidinium receptive site distinct from the alpha 2-adrenergic receptor J. Biol. Chem. 264 1989 11874 11878 (Pubitemid 19185356)
46. R. Paus, M. Schmelz, T. Bíró, and M. Steinhoff Frontiers in pruritus research: scratching the brain for more effective itch therapy J. Clin. Invest. 116 2006 1174 1186
47. G. Peer, S. Kivity, O. Agami, E. Fireman, D. Silverberg, M. Blum, and A. laina Randomised crossover trial of naltrexone in uraemic pruritus Lancet 348 1996 1552 1554
48. A. Sasaki, I. Takasaki, T. Andoh, H. Nojima, K. Shiraki, and Y. Kuraishi Roles of α-adrenoceptors and sympathetic nerve in acute herpetic pain induced by herpes simplex virus inoculation in mice J. Pharmacol. Sci. 92 2003 329 336 (Pubitemid 37086714)
49. J. Schwartz, and V. Rosenfeld Clonidine for painful diabetic-uremic leg cramps and pruritus-a case report Angiology 44 1993 985 (Pubitemid 23356615)
50. 2-adrenoceptor mRNAs in the rat lumbar spinal cord in normal and axotomized rats Neuroreport 10 1999 2835 2839 (Pubitemid 30004114)
51. S.G. Shimada, and R.H. LaMotte Behavioral differentiation between itch and pain in mouse Pain 139 2008 681 687
52. 2C adrenergic receptor immunoreactivity in the rat spinal cord J. Neurosci. 18 1998 5928 5937 (Pubitemid 28341368)
53. M. Sugimoto, Y. Kuraishi, M. Satoh, and H. Takagi Involvement of medullary opioid-peptidergic and spinal noradrenergic systems in the regulation of formalin-induced persistent pain Neuropharmacology 25 1986 481 485 (Pubitemid 16036362)
54. Y.G. Sun, Z.Q. Zhao, X.L. Meng, J. Yin, X.Y. Liu, and Z.F. Chen Cellular basis of itch sensation Science 325 2009 1531 1534
55. K. Taguchi, M. Yang, M. Goepel, and M.C. Michel Comparison of human alpha1-adrenoceptor subtype coupling to protein kinase C activation and related signalling pathways Naunyn Schmiedebergs Arch. Pharmacol. 357 1998 100 110 (Pubitemid 28085509)
56. 2 agonists Peptides 14 1993 371 378
57. M. Ueda, T. Oyama, Y. Kuraishi, A. Akaike, and M. Satoh Alphar2-adrenoceptor-mediated inhibition of capsaicin-evoked release of glutamate from rat spinal dorsal horn slices Neurosci. Lett. 188 1995 137 139
58. 3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors J. Pharmacol. Exp. Ther. 271 1994 1558 1565 (Pubitemid 24382671)
59. H. Ui, T. Andoh, J.B. Lee, H. Nojima, and Y. Kuraishi Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice Eur. J. Pharmacol. 530 2006 172 178 (Pubitemid 43037138)
60. C.-F. Wahlgren Itch and atopic dermatitis: clinical and experimental studies Acta Derm. Venereol. 165 Suppl. 1991 1 53
61. T.L. Yaksh Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists Pain 37 1989 111 123 (Pubitemid 19095624)
62. T. Yamaguchi, T. Maekawa, Y. Nishikawa, H. Nojima, M. Kaneko, T. Kawakita, T. Miyamamot, and Y. Kuraishi Characterization of itch-associated responses of NC mice with mite-induced chronic dermatitis J. Dermatol. Sci. 25 2001 20 28 (Pubitemid 32012642)
63. 2 receptors in mice Neurosci. Res. 35 1999 77 83 (Pubitemid 29518398)