-
1
-
-
33847125757
-
Pharmacokinetics of oral doses of telmisartan and nisoldipine, given alone and in combination, in patients with essential hypertension
-
Bajcetic M, Benndorf RA, Appel D, Schwedhelm E, Schulze F, Riekhof D, Maas R and Boger R (2007) Pharmacokinetics of oral doses of telmisartan and nisoldipine, given alone and in combination, in patients with essential hypertension. J Clin Pharmacol 47:295-304.
-
(2007)
J Clin Pharmacol
, vol.47
, pp. 295-304
-
-
Bajcetic, M.1
Benndorf, R.A.2
Appel, D.3
Schwedhelm, E.4
Schulze, F.5
Riekhof, D.6
Maas, R.7
Boger, R.8
-
2
-
-
16244408295
-
Levofloxacin and ciprofloxacin decrease procainamide and N-acetylprocainamide renal clearances
-
Bauer LA, Black DJ, Lill JS, Garrison J, Raisys VA and Hooton TM (2005) Levofloxacin and ciprofloxacin decrease procainamide and N-acetylprocainamide renal clearances. Antimicrob Agents Chemother 49:1649-1651.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 1649-1651
-
-
Bauer, L.A.1
Black, D.J.2
Lill, J.S.3
Garrison, J.4
Raisys, V.A.5
Hooton, T.M.6
-
3
-
-
0032529428
-
Effect of multidrug resistance modulators on the hepatobiliary disposition of doxorubicin in the isolated perfused rat liver
-
Booth CL, Brouwer KR and Brouwer KL (1998) Effect of multidrug resistance modulators on the hepatobiliary disposition of doxorubicin in the isolated perfused rat liver. Cancer Res 58:3641-3648.
-
(1998)
Cancer Res
, vol.58
, pp. 3641-3648
-
-
Booth, C.L.1
Brouwer, K.R.2
Brouwer, K.L.3
-
4
-
-
0035987894
-
Tissue distribution and chemical induction of multiple drug resistance genes in rats
-
Brady JM, Cherrington NJ, Hartley DP, Buist SC, Li N and Klaassen CD (2002) Tissue distribution and chemical induction of multiple drug resistance genes in rats. Drug Metab Dispos 30:838-844.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 838-844
-
-
Brady, J.M.1
Cherrington, N.J.2
Hartley, D.P.3
Buist, S.C.4
Li, N.5
Klaassen, C.D.6
-
5
-
-
4143142207
-
Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: Potential role for breast cancer resistance protein in clinical drug-drug interactions
-
Breedveld P, Zelcer N, Pluim D, Sonmezer O, Tibben MM, Beijnen JH, Schinkel AH, Van Tellingen O, Borst P and Schellens JH (2004) Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. Cancer Res 64:5804-5811.
-
(2004)
Cancer Res
, vol.64
, pp. 5804-5811
-
-
Breedveld, P.1
Zelcer, N.2
Pluim, D.3
Sonmezer, O.4
Tibben, M.M.5
Beijnen, J.H.6
Schinkel, A.H.7
Van Tellingen, O.8
Borst, P.9
Schellens, J.H.10
-
6
-
-
0027171710
-
Effect of probenecid on cefazolin serum concentrations
-
Brown G, Zemcov SJ and Clarke AM (1993) Effect of probenecid on cefazolin serum concentrations. J Antimicrob Chemother 31:1009-1011.
-
(1993)
J Antimicrob Chemother
, vol.31
, pp. 1009-1011
-
-
Brown, G.1
Zemcov, S.J.2
Clarke, A.M.3
-
7
-
-
0030069988
-
Influence of cimetidine coadministration on the pharmacokinetics of sotalol enantiomers in an anaesthetized rat model: Evidence supporting active renal excretion of sotalol
-
Carr RA, Pasutto FM and Foster RT (1996) Influence of cimetidine coadministration on the pharmacokinetics of sotalol enantiomers in an anaesthetized rat model: evidence supporting active renal excretion of sotalol. Biopharm Drug Dispos 17:55-69.
-
(1996)
Biopharm Drug Dispos
, vol.17
, pp. 55-69
-
-
Carr, R.A.1
Pasutto, F.M.2
Foster, R.T.3
-
8
-
-
0000518648
-
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta
-
Cha SH, Sekine T, Kusuhara H, Yu E, Kim JY, Kim DK, Sugiyama Y, Kanai Y and Endou H (2000) Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J Biol Chem 275:4507-4512.
-
(2000)
J Biol Chem
, vol.275
, pp. 4507-4512
-
-
Cha, S.H.1
Sekine, T.2
Kusuhara, H.3
Yu, E.4
Kim, J.Y.5
Kim, D.K.6
Sugiyama, Y.7
Kanai, Y.8
Endou, H.9
-
9
-
-
0036137072
-
Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats
-
Cherrington NJ, Hartley DP, Li N, Johnson DR and Klaassen CD (2002) Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats. J Pharmacol Exp Ther 300:97-104.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 97-104
-
-
Cherrington, N.J.1
Hartley, D.P.2
Li, N.3
Johnson, D.R.4
Klaassen, C.D.5
-
10
-
-
25844530136
-
Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers
-
Chung JY, Cho JY, Yu KS, Kim JR, Oh DS, Jung HR, Lim KS, Moon KH, Shin SG and Jang IJ (2005) Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers. Clin Pharmacol Ther 78:342-350.
-
(2005)
Clin Pharmacol Ther
, vol.78
, pp. 342-350
-
-
Chung, J.Y.1
Cho, J.Y.2
Yu, K.S.3
Kim, J.R.4
Oh, D.S.5
Jung, H.R.6
Lim, K.S.7
Moon, K.H.8
Shin, S.G.9
Jang, I.J.10
-
11
-
-
0024544045
-
The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues
-
Croop JM, Raymond M, Haber D, Devault A, Arceci RJ, Gros P and Housman DE (1989) The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues. Mol Cell Biol 9:1346-1350.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1346-1350
-
-
Croop, J.M.1
Raymond, M.2
Haber, D.3
Devault, A.4
Arceci, R.J.5
Gros, P.6
Housman, D.E.7
-
12
-
-
0030918044
-
Effect of the P-glycoprotein inhibitor, SDZ PSC 833, on the blood and brain pharmacokinetics of colchicine
-
Desrayaud S, Guntz P, Scherrmann JM and Lemaire M (1997) Effect of the P-glycoprotein inhibitor, SDZ PSC 833, on the blood and brain pharmacokinetics of colchicine. Life Sci 61:153-163.
-
(1997)
Life Sci
, vol.61
, pp. 153-163
-
-
Desrayaud, S.1
Guntz, P.2
Scherrmann, J.M.3
Lemaire, M.4
-
13
-
-
3042568988
-
Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers
-
Ding R, Tayrouz Y, Riedel KD, Burhenne J, Weiss J, Mikus G and Haefeli WE (2004) Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers. Clin Pharmacol Ther 76:73-84.
-
(2004)
Clin Pharmacol Ther
, vol.76
, pp. 73-84
-
-
Ding, R.1
Tayrouz, Y.2
Riedel, K.D.3
Burhenne, J.4
Weiss, J.5
Mikus, G.6
Haefeli, W.E.7
-
14
-
-
0035066252
-
Transporters involved in the elimination of drugs in the kidney: Organic anion transporters and organic cation transporters
-
Dresser MJ, Leabman MK and Giacomini KM (2001) Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters. J Pharm Sci 90:397-421.
-
(2001)
J Pharm Sci
, vol.90
, pp. 397-421
-
-
Dresser, M.J.1
Leabman, M.K.2
Giacomini, K.M.3
-
15
-
-
68149151186
-
Effects of drug transporters on volume of distribution
-
Grover A and Benet LZ (2009) Effects of drug transporters on volume of distribution. AAPS J 11:250-261.
-
(2009)
AAPS J
, vol.11
, pp. 250-261
-
-
Grover, A.1
Benet, L.Z.2
-
17
-
-
1242272736
-
Organic anion transporting polypeptides of the OATP/SLC21 family: Phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties
-
Hagenbuch B and Meier PJ (2004) Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch 447:653-665.
-
(2004)
Pflugers Arch
, vol.447
, pp. 653-665
-
-
Hagenbuch, B.1
Meier, P.J.2
-
18
-
-
23944475903
-
Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin
-
Hirano M, Maeda K, Matsushima S, Nozaki Y, Kusuhara H and Sugiyama Y (2005) Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin. Mol Pharmacol 68:800-807.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 800-807
-
-
Hirano, M.1
Maeda, K.2
Matsushima, S.3
Nozaki, Y.4
Kusuhara, H.5
Sugiyama, Y.6
-
19
-
-
0025055624
-
The inhibitory effect of probenecid on renal excretion of famotidine in young, healthy volunteers
-
Inotsume N, Nishimura M, Nakano M, Fujiyama S and Sato T (1990) The inhibitory effect of probenecid on renal excretion of famotidine in young, healthy volunteers. J Clin Pharmacol 30:50-56.
-
(1990)
J Clin Pharmacol
, vol.30
, pp. 50-56
-
-
Inotsume, N.1
Nishimura, M.2
Nakano, M.3
Fujiyama, S.4
Sato, T.5
-
20
-
-
0028822282
-
Effect of probenecid on the distribution and elimination of ciprofloxacin in humans
-
Jaehde U, Sorgel F, Reiter A, Sigl G, Naber KG and Schunack W (1995) Effect of probenecid on the distribution and elimination of ciprofloxacin in humans. Clin Pharmacol Ther 58:532-541.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 532-541
-
-
Jaehde, U.1
Sorgel, F.2
Reiter, A.3
Sigl, G.4
Naber, K.G.5
Schunack, W.6
-
21
-
-
0029938602
-
Cyclosporin A treatment induces overexpression of P-glycoprotein in the kidney and other tissues
-
Jette L, Beaulieu E, Leclerc JM and Beliveau R (1996) Cyclosporin A treatment induces overexpression of P-glycoprotein in the kidney and other tissues. Am J Physiol 270:F756-765.
-
(1996)
Am J Physiol
, vol.270
-
-
Jette, L.1
Beaulieu, E.2
Leclerc, J.M.3
Beliveau, R.4
-
22
-
-
25844438751
-
Cyclosporine markedly raises the plasma concentrations of repaglinide
-
Kajosaari LI, Niemi M, Neuvonen M, Laitila J, Neuvonen PJ and Backman JT (2005) Cyclosporine markedly raises the plasma concentrations of repaglinide. Clin Pharmacol Ther 78:388-399.
-
(2005)
Clin Pharmacol Ther
, vol.78
, pp. 388-399
-
-
Kajosaari, L.I.1
Niemi, M.2
Neuvonen, M.3
Laitila, J.4
Neuvonen, P.J.5
Backman, J.T.6
-
23
-
-
0022885525
-
The effect of verapamil on the pharmacokinetics of adriamycin
-
Kerr DJ, Graham J, Cummings J, Morrison JG, Thompson GG, Brodie MJ and Kaye SB (1986) The effect of verapamil on the pharmacokinetics of adriamycin. Cancer Chemother Pharmacol 18:239-242.
-
(1986)
Cancer Chemother Pharmacol
, vol.18
, pp. 239-242
-
-
Kerr, D.J.1
Graham, J.2
Cummings, J.3
Morrison, J.G.4
Thompson, G.G.5
Brodie, M.J.6
Kaye, S.B.7
-
24
-
-
10744219672
-
Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics
-
Khamdang S, Takeda M, Babu E, Noshiro R, Onozato ML, Tojo A, Enomoto A, Huang XL, Narikawa S, Anzai N, Piyachaturawat P and Endou H (2003) Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. Eur J Pharmacol 465:1-7.
-
(2003)
Eur J Pharmacol
, vol.465
, pp. 1-7
-
-
Khamdang, S.1
Takeda, M.2
Babu, E.3
Noshiro, R.4
Onozato, M.L.5
Tojo, A.6
Enomoto, A.7
Huang, X.L.8
Narikawa, S.9
Anzai, N.10
Piyachaturawat, P.11
Endou, H.12
-
25
-
-
0036084956
-
Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice
-
Kobayashi Y, Ohshiro N, Shibusawa A, Sasaki T, Tokuyama S, Sekine T, Endou H and Yamamoto T (2002) Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice. Mol Pharmacol 62:7-14.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 7-14
-
-
Kobayashi, Y.1
Ohshiro, N.2
Shibusawa, A.3
Sasaki, T.4
Tokuyama, S.5
Sekine, T.6
Endou, H.7
Yamamoto, T.8
-
26
-
-
0030513880
-
Tubular transport mechanisms of quinapril and quinaprilat in the isolated perfused rat kidney: Effect of organic anions and cations
-
Kugler AR, Olson SC and Smith DE (1996) Tubular transport mechanisms of quinapril and quinaprilat in the isolated perfused rat kidney: effect of organic anions and cations. J Pharmacokinet Biopharm 24:349-368.
-
(1996)
J Pharmacokinet Biopharm
, vol.24
, pp. 349-368
-
-
Kugler, A.R.1
Olson, S.C.2
Smith, D.E.3
-
27
-
-
0031793118
-
Renal excretion of rhodamine 123, a P-glycoprotein substrate, in rats with glycerol-induced acute renal failure
-
Kunihara M, Nagai J, Murakami T and Takano M (1998) Renal excretion of rhodamine 123, a P-glycoprotein substrate, in rats with glycerol-induced acute renal failure. J Pharm Pharmacol 50:1161-1165.
-
(1998)
J Pharm Pharmacol
, vol.50
, pp. 1161-1165
-
-
Kunihara, M.1
Nagai, J.2
Murakami, T.3
Takano, M.4
-
28
-
-
33751160865
-
Elucidating the effect of final-day dosing of rifampin in induction studies on hepatic drug disposition and metabolism
-
Lam JL, Shugarts SB, Okochi H and Benet LZ (2006) Elucidating the effect of final-day dosing of rifampin in induction studies on hepatic drug disposition and metabolism. J Pharmacol Exp Ther 319:864-870.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 864-870
-
-
Lam, J.L.1
Shugarts, S.B.2
Okochi, H.3
Benet, L.Z.4
-
29
-
-
68249151942
-
-
dissertation, University of California, San Francisco
-
Lau YY (2006) Examining the Regulation of Hepatic Drug Disposition and Metabolism by Organic Anion Transporting Peptide, P-Glycoprotein, and Multidrug Resistance-Associated Protein 2 [dissertation], University of California, San Francisco.
-
(2006)
Examining the Regulation of Hepatic Drug Disposition and Metabolism by Organic Anion Transporting Peptide, P-glycoprotein, and Multidrug Resistance-associated Protein
, pp. 2
-
-
Lau, Y.Y.1
-
30
-
-
33846571368
-
Effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers
-
Lau YY, Huang Y, Frassetto L and Benet LZ (2007) Effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers. Clin Pharmacol Ther 81:194-204.
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 194-204
-
-
Lau, Y.Y.1
Huang, Y.2
Frassetto, L.3
Benet, L.Z.4
-
31
-
-
0023838424
-
Kinetic studies on the competition between famotidine and cimetidine in rats. evidence of multiple renal secretory systems for organic cations
-
Lin JH, Los LE, Ulm EH and Duggan DE (1988) Kinetic studies on the competition between famotidine and cimetidine in rats. evidence of multiple renal secretory systems for organic cations. Drug Metab Dispos 16:52-56.
-
(1988)
Drug Metab Dispos
, vol.16
, pp. 52-56
-
-
Lin, J.H.1
Los, L.E.2
Ulm, E.H.3
Duggan, D.E.4
-
32
-
-
0033064071
-
Increase in cerivastatin systemic exposure after single and multiple dosing in cyclosporine-treated kidney transplant recipients
-
Muck W, Mai I, Fritsche L, Ochmann K, Rohde G, Unger S, Johne A, Bauer S, Budde K, Roots I, Neumayer HH and Kuhlmann J (1999) Increase in cerivastatin systemic exposure after single and multiple dosing in cyclosporine-treated kidney transplant recipients. Clin Pharmacol Ther 65:251-261.
-
(1999)
Clin Pharmacol Ther
, vol.65
, pp. 251-261
-
-
Muck, W.1
Mai, I.2
Fritsche, L.3
Ochmann, K.4
Rohde, G.5
Unger, S.6
Johne, A.7
Bauer, S.8
Budde, K.9
Roots, I.10
Neumayer, H.H.11
Kuhlmann, J.12
-
33
-
-
0024244938
-
General treatment of mean residence time, clearance, and volume parameters in linear mammillary models with elimination from any compartment
-
Nakashima E and Benet LZ (1988) General treatment of mean residence time, clearance, and volume parameters in linear mammillary models with elimination from any compartment. J Pharmacokinet Biopharm 16:475-492.
-
(1988)
J Pharmacokinet Biopharm
, vol.16
, pp. 475-492
-
-
Nakashima, E.1
Benet, L.Z.2
-
34
-
-
0027949321
-
Pharmacokinetics and safety of NM441, a new quinolone, in healthy male volunteers
-
Nakashima M, Uematsu T, Kosuge K, Okuyama Y, Morino A, Ozaki M and Takebe Y (1994) Pharmacokinetics and safety of NM441, a new quinolone, in healthy male volunteers. J Clin Pharmacol 34:930-937.
-
(1994)
J Clin Pharmacol
, vol.34
, pp. 930-937
-
-
Nakashima, M.1
Uematsu, T.2
Kosuge, K.3
Okuyama, Y.4
Morino, A.5
Ozaki, M.6
Takebe, Y.7
-
35
-
-
0023203010
-
Effects of verapamil on the pharmacokinetics of daunomycin in the rat
-
Nooter K, Oostrum R and Deurloo J (1987) Effects of verapamil on the pharmacokinetics of daunomycin in the rat. Cancer Chemother Pharmacol 20:176-178.
-
(1987)
Cancer Chemother Pharmacol
, vol.20
, pp. 176-178
-
-
Nooter, K.1
Oostrum, R.2
Deurloo, J.3
-
36
-
-
27744438584
-
Pharmacokinetic interaction of tetracycline with non-steroidal antiinflammatory drugs via organic anion transporters in rats
-
Oh YH and Han H (2006) Pharmacokinetic interaction of tetracycline with non-steroidal antiinflammatory drugs via organic anion transporters in rats. Pharmacol Res 53:75-79.
-
(2006)
Pharmacol Res
, vol.53
, pp. 75-79
-
-
Oh, Y.H.1
Han, H.2
-
37
-
-
0023024309
-
Drug distribution and binding
-
Øie S (1986) Drug distribution and binding. J Clin Pharmacol 26:583-586.
-
(1986)
J Clin Pharmacol
, vol.26
, pp. 583-586
-
-
Øie, S.1
-
38
-
-
36148953896
-
Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin
-
Pasanen MK, Fredrikson H, Neuvonen PJ and Niemi M (2007) Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin. Clin Pharmacol Ther 82:726-733.
-
(2007)
Clin Pharmacol Ther
, vol.82
, pp. 726-733
-
-
Pasanen, M.K.1
Fredrikson, H.2
Neuvonen, P.J.3
Niemi, M.4
-
39
-
-
0034004157
-
Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and roct
-
Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS and Nigam SK (2000) Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and roct. Am J Physiol Renal Physiol 278:F635-643.
-
(2000)
Am J Physiol Renal Physiol
, vol.278
-
-
Pavlova, A.1
Sakurai, H.2
Leclercq, B.3
Beier, D.R.4
Yu, A.S.5
Nigam, S.K.6
-
40
-
-
57149145435
-
The operational multiple dosing half-life: A key to defining drug accumulation in patients and to designing extended release dosage forms
-
Sahin S and Benet LZ (2008) The operational multiple dosing half-life: a key to defining drug accumulation in patients and to designing extended release dosage forms. Pharm Res 25:2869-2877.
-
(2008)
Pharm Res
, vol.25
, pp. 2869-2877
-
-
Sahin, S.1
Benet, L.Z.2
-
41
-
-
29244454212
-
Pharmacokinetic significance of renal OAT3 (SLC22A8) for anionic drug elimination in patients with mesangial proliferative glomerulonephritis
-
Sakurai Y, Motohashi H, Ogasawara K, Terada T, Masuda S, Katsura T, Mori N, Matsuura M, Doi T, Fukatsu A and Inui K (2005) Pharmacokinetic significance of renal OAT3 (SLC22A8) for anionic drug elimination in patients with mesangial proliferative glomerulonephritis. Pharm Res 22:2016-2022.
-
(2005)
Pharm Res
, vol.22
, pp. 2016-2022
-
-
Sakurai, Y.1
Motohashi, H.2
Ogasawara, K.3
Terada, T.4
Masuda, S.5
Katsura, T.6
Mori, N.7
Matsuura, M.8
Doi, T.9
Fukatsu, A.10
Inui, K.11
-
42
-
-
11144354934
-
The effect of gemfibrozil on the pharmacokinetics of rosuvastatin
-
Schneck DW, Birmingham BK, Zalikowski JA, Mitchell PD, Wang Y, Martin PD, Lasseter KC, Brown CD, Windass AS and Raza A (2004) The effect of gemfibrozil on the pharmacokinetics of rosuvastatin. Clin Pharmacol Ther 75:455-463.
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 455-463
-
-
Schneck, D.W.1
Birmingham, B.K.2
Zalikowski, J.A.3
Mitchell, P.D.4
Wang, Y.5
Martin, P.D.6
Lasseter, K.C.7
Brown, C.D.8
Windass, A.S.9
Raza, A.10
-
43
-
-
0033938669
-
The multispecific organic anion transporter (OAT) family
-
Sekine T, Cha SH and Endou H (2000) The multispecific organic anion transporter (OAT) family. Pflugers Arch 440:337-350.
-
(2000)
Pflugers Arch
, vol.440
, pp. 337-350
-
-
Sekine, T.1
Cha, S.H.2
Endou, H.3
-
44
-
-
0034025366
-
Effect of cimetidine and probenecid on pilsicainide renal clearance in humans
-
Shiga T, Hashiguchi M, Urae A, Kasanuki H and Rikihisa T (2000) Effect of cimetidine and probenecid on pilsicainide renal clearance in humans. Clin Pharmacol Ther 67:222-228.
-
(2000)
Clin Pharmacol Ther
, vol.67
, pp. 222-228
-
-
Shiga, T.1
Hashiguchi, M.2
Urae, A.3
Kasanuki, H.4
Rikihisa, T.5
-
45
-
-
33644847684
-
Transporters as a determinant of drug clearance and tissue distribution
-
Shitara Y, Horie T and Sugiyama Y (2006) Transporters as a determinant of drug clearance and tissue distribution. Eur J Pharm Sci 27:425-446.
-
(2006)
Eur J Pharm Sci
, vol.27
, pp. 425-446
-
-
Shitara, Y.1
Horie, T.2
Sugiyama, Y.3
-
46
-
-
13844314148
-
Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs
-
Shitara Y, Sato H and Sugiyama Y (2005) Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs. Annu Rev Pharmacol Toxicol 45:689-723.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 689-723
-
-
Shitara, Y.1
Sato, H.2
Sugiyama, Y.3
-
47
-
-
38349085099
-
Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics
-
Shu Y, Brown C, Castro RA, Shi RJ, Lin ET, Owen RP, Sheardown SA, Yue L, Burchard EG, Brett CM and Giacomini KM (2008) Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics. Clin Pharmacol Ther 83:273-280.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 273-280
-
-
Shu, Y.1
Brown, C.2
Castro, R.A.3
Shi, R.J.4
Lin, E.T.5
Owen, R.P.6
Sheardown, S.A.7
Yue, L.8
Burchard, E.G.9
Brett, C.M.10
Giacomini, K.M.11
-
48
-
-
3542992126
-
Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine
-
Simonson SG, Raza A, Martin PD, Mitchell PD, Jarcho JA, Brown CD, Windass AS and Schneck DW (2004) Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine. Clin Pharmacol Ther 76:167-177.
-
(2004)
Clin Pharmacol Ther
, vol.76
, pp. 167-177
-
-
Simonson, S.G.1
Raza, A.2
Martin, P.D.3
Mitchell, P.D.4
Jarcho, J.A.5
Brown, C.D.6
Windass, A.S.7
Schneck, D.W.8
-
49
-
-
0020635466
-
Cimetidine-procainamide pharmacokinetic interaction in man: Evidence of competition for tubular secretion of basic drugs
-
Somogyi A, McLean A and Heinzow B (1983) Cimetidine-procainamide pharmacokinetic interaction in man: evidence of competition for tubular secretion of basic drugs. Eur J Clin Pharmacol 25:339-345.
-
(1983)
Eur J Clin Pharmacol
, vol.25
, pp. 339-345
-
-
Somogyi, A.1
McLean, A.2
Heinzow, B.3
-
50
-
-
0026603791
-
Effect of cyclosporine on colchicine secretion by a liver canalicular transporter studied in vivo
-
Speeg KV, Maldonado AL, Liaci J and Muirhead D (1992) Effect of cyclosporine on colchicine secretion by a liver canalicular transporter studied in vivo. Hepatology 15:899-903.
-
(1992)
Hepatology
, vol.15
, pp. 899-903
-
-
Speeg, K.V.1
Maldonado, A.L.2
Liaci, J.3
Muirhead, D.4
-
51
-
-
44849122024
-
Using novobiocin as a specific inhibitor of breast cancer resistant protein to assess the role of transporter in the absorption and disposition of topotecan
-
Su Y, Hu P, Lee SH and Sinko PJ (2007) Using novobiocin as a specific inhibitor of breast cancer resistant protein to assess the role of transporter in the absorption and disposition of topotecan. J Pharm Pharmaceut Sci 10:519-536.
-
(2007)
J Pharm Pharmaceut Sci
, vol.10
, pp. 519-536
-
-
Su, Y.1
Hu, P.2
Lee, S.H.3
Sinko, P.J.4
-
52
-
-
0037178852
-
Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice
-
Sweet DH, Miller DS, Pritchard JB, Fujiwara Y, Beier DR and Nigam SK (2002) Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. J Biol Chem 277:26934-26943.
-
(2002)
J Biol Chem
, vol.277
, pp. 26934-26943
-
-
Sweet, D.H.1
Miller, D.S.2
Pritchard, J.B.3
Fujiwara, Y.4
Beier, D.R.5
Nigam, S.K.6
-
53
-
-
16644386102
-
Effect of genetic polymorphism of OATP-C (SLCO1B1) on lipid-lowering response to HMG-CoA reductase inhibitors
-
Tachibana-Iimori R, Tabara Y, Kusuhara H, Kohara K, Kawamoto R, Nakura J, Tokunaga K, Kondo I, Sugiyama Y and Miki T (2004) Effect of genetic polymorphism of OATP-C (SLCO1B1) on lipid-lowering response to HMG-CoA reductase inhibitors. Drug Metab Pharmacokinet 19:375-380.
-
(2004)
Drug Metab Pharmacokinet
, vol.19
, pp. 375-380
-
-
Tachibana-Iimori, R.1
Tabara, Y.2
Kusuhara, H.3
Kohara, K.4
Kawamoto, R.5
Nakura, J.6
Tokunaga, K.7
Kondo, I.8
Sugiyama, Y.9
Miki, T.10
-
54
-
-
33644749355
-
Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists
-
Tahara H, Kusuhara H, Chida M, Fuse E and Sugiyama Y (2006) Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists. J Pharmacol Exp Ther 316:1187-1194.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 1187-1194
-
-
Tahara, H.1
Kusuhara, H.2
Chida, M.3
Fuse, E.4
Sugiyama, Y.5
-
55
-
-
9644282955
-
Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice
-
Tanaka Y, Slitt AL, Leazer TM, Maher JM and Klaassen CD (2005) Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice. Biochem Biophys Res Commun 326:181-187.
-
(2005)
Biochem Biophys Res Commun
, vol.326
, pp. 181-187
-
-
Tanaka, Y.1
Slitt, A.L.2
Leazer, T.M.3
Maher, J.M.4
Klaassen, C.D.5
-
56
-
-
0018896015
-
Biliary and urinary excretion of adriamycin in anesthetized rats
-
Tavoloni N and Guarino AM (1980) Biliary and urinary excretion of adriamycin in anesthetized rats. Pharmacology 20:256-267.
-
(1980)
Pharmacology
, vol.20
, pp. 256-267
-
-
Tavoloni, N.1
Guarino, A.M.2
-
57
-
-
33646094207
-
Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: First case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2
-
Tsuruoka S, Ioka T, Wakaumi M, Sakamoto K, Ookami H and Fujimura A (2006) Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: first case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2. Clin Pharmacol Ther 79:389-396.
-
(2006)
Clin Pharmacol Ther
, vol.79
, pp. 389-396
-
-
Tsuruoka, S.1
Ioka, T.2
Wakaumi, M.3
Sakamoto, K.4
Ookami, H.5
Fujimura, A.6
-
58
-
-
0033250793
-
Affinity of drugs to the different renal transporters for organic anions and organic cations
-
Amidon GL and Sadee W eds, Kluwer Academic/Plenum Publishers, New York
-
Ullrich K (1999) Affinity of drugs to the different renal transporters for organic anions and organic cations, in Membrane Transporters as Drug Targets (Amidon GL and Sadee W eds) pp 159-179, Kluwer Academic/Plenum Publishers, New York.
-
(1999)
Membrane Transporters as Drug Targets
, pp. 159-179
-
-
Ullrich, K.1
-
59
-
-
0025105779
-
Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues. Analysis with 3 monoclonal antibodies recognizing different epitopes of the P-glycoprotein molecule
-
Van Der Valk P, Van Kalken CK, Ketelaars H, Broxterman HJ, Scheffer G, Kuiper CM, Tsuruo T, Lankelma J, Meijer CJ and Pinedo HM (1990) Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues. Analysis with 3 monoclonal antibodies recognizing different epitopes of the P-glycoprotein molecule. Ann Oncol 1:56-64.
-
(1990)
Ann Oncol
, vol.1
, pp. 56-64
-
-
Van Der Valk, P.1
Van Kalken, C.K.2
Ketelaars, H.3
Broxterman, H.J.4
Scheffer, G.5
Kuiper, C.M.6
Tsuruo, T.7
Lankelma, J.8
Meijer, C.J.9
Pinedo, H.M.10
-
60
-
-
0036020408
-
Cyclosporin increases the exposure to tezosentan, an intravenous dual endothelin receptor antagonist
-
Van Giersbergen PL, Bodin F and Dingemanse J (2002) Cyclosporin increases the exposure to tezosentan, an intravenous dual endothelin receptor antagonist. Eur J Clin Pharmacol 58:243-245.
-
(2002)
Eur J Clin Pharmacol
, vol.58
, pp. 243-245
-
-
Van Giersbergen, P.L.1
Bodin, F.2
Dingemanse, J.3
-
61
-
-
35348889668
-
Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G
-
Van Wert AL, Bailey RM and Sweet DH (2007) Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G. Am J Physiol 293:F1332-F1341.
-
(2007)
Am J Physiol
, vol.293
-
-
Van Wert, A.L.1
Bailey, R.M.2
Sweet, D.H.3
-
62
-
-
0028998552
-
Effect of the P-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: An in vivo microdialysis study in freely moving rats
-
Wang Q, Yang H, Miller DW and Elmquist WF (1995) Effect of the P-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: an in vivo microdialysis study in freely moving rats. Biochem Biophys Res Commun 211:719-726.
-
(1995)
Biochem Biophys Res Commun
, vol.211
, pp. 719-726
-
-
Wang, Q.1
Yang, H.2
Miller, D.W.3
Elmquist, W.F.4
-
64
-
-
38449092450
-
Transportermediated hepatic uptake of ulifloxacin, an active metabolite of a prodrug-type new quinolone antibiotic prulifloxacin, in rats
-
Yagi Y, Aoki M, Iguchi M, Shibasaki S, Kurosawa T, Kato Y and Tsuji A (2007) Transportermediated hepatic uptake of ulifloxacin, an active metabolite of a prodrug-type new quinolone antibiotic prulifloxacin, in rats. Drug Metab Pharmacokinet 22:350-357.
-
(2007)
Drug Metab Pharmacokinet
, vol.22
, pp. 350-357
-
-
Yagi, Y.1
Aoki, M.2
Iguchi, M.3
Shibasaki, S.4
Kurosawa, T.5
Kato, Y.6
Tsuji, A.7
-
65
-
-
3042812719
-
Involvement of multiple transport systems in the disposition of an active metabolite of a prodrug-type new quinolone antibiotic, prulifloxacin
-
Yagi Y, Shibutani S, Hodoshima N, Ishiwata K, Okudaira N, Li Q, Sai Y, Kato Y and Tsuji A (2003) Involvement of multiple transport systems in the disposition of an active metabolite of a prodrug-type new quinolone antibiotic, prulifloxacin. Drug Metab Pharmacokinet 18:381-389.
-
(2003)
Drug Metab Pharmacokinet
, vol.18
, pp. 381-389
-
-
Yagi, Y.1
Shibutani, S.2
Hodoshima, N.3
Ishiwata, K.4
Okudaira, N.5
Li, Q.6
Sai, Y.7
Kato, Y.8
Tsuji, A.9
-
66
-
-
33745231761
-
Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans
-
Yamashiro W, Maeda K, Hirouchi M, Adachi Y, Hu Z and Sugiyama Y (2006) Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans. Drug Metab Dispos 34:1247-1254.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1247-1254
-
-
Yamashiro, W.1
Maeda, K.2
Hirouchi, M.3
Adachi, Y.4
Hu, Z.5
Sugiyama, Y.6
-
67
-
-
49249130070
-
Oral and IV dosing: A method to determine the compartment of drug elimination for two-compartment models
-
Yates JW and Arundel PA (2008a) Oral and IV dosing: a method to determine the compartment of drug elimination for two-compartment models. J Pharm Sci 97:2036-2040.
-
(2008)
J Pharm Sci
, vol.97
, pp. 2036-2040
-
-
Yates, J.W.1
Arundel, P.A.2
-
68
-
-
38349116925
-
On the volume of distribution at steady state and its relationship with two-compartmental models
-
Yates JW and Arundel PA (2008b) On the volume of distribution at steady state and its relationship with two-compartmental models. J Pharm Sci 97:111-122.
-
(2008)
J Pharm Sci
, vol.97
, pp. 111-122
-
-
Yates, J.W.1
Arundel, P.A.2
-
69
-
-
0015348503
-
Comparative pharmacokinetics of daunomycin and adriamycin in several animal species
-
Yesair DW, Schwartzbach E, Shuck D, Denine EP and Asbell MA (1972) Comparative pharmacokinetics of daunomycin and adriamycin in several animal species. Cancer Res 32:1177-1183.
-
(1972)
Cancer Res
, vol.32
, pp. 1177-1183
-
-
Yesair, D.W.1
Schwartzbach, E.2
Shuck, D.3
Denine, E.P.4
Asbell, M.A.5
-
70
-
-
0032807119
-
P-glycoprotein-dependent disposition kinetics of tacrolimus: Studies in mdr1a knockout mice
-
Yokogawa K, Takahashi M, Tamai I, Konishi H, Nomura M, Moritani S, Miyamoto K and Tsuji A (1999) P-glycoprotein-dependent disposition kinetics of tacrolimus: studies in mdr1a knockout mice. Pharm Res 16:1213-1218.
-
(1999)
Pharm Res
, vol.16
, pp. 1213-1218
-
-
Yokogawa, K.1
Takahashi, M.2
Tamai, I.3
Konishi, H.4
Nomura, M.5
Moritani, S.6
Miyamoto, K.7
Tsuji, A.8
-
71
-
-
15444358162
-
Probenecid alters topotecan systemic and renal disposition by inhibiting renal tubular secretion
-
Zamboni WC, Houghton PJ, Johnson RK, Hulstein JL, Crom WR, Cheshire PJ, Hanna SK, Richmond LB, Luo X and Stewart CF (1998) Probenecid alters topotecan systemic and renal disposition by inhibiting renal tubular secretion. J Pharmacol Exp Ther 284:89-94.
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 89-94
-
-
Zamboni, W.C.1
Houghton, P.J.2
Johnson, R.K.3
Hulstein, J.L.4
Crom, W.R.5
Cheshire, P.J.6
Hanna, S.K.7
Richmond, L.B.8
Luo, X.9
Stewart, C.F.10
-
72
-
-
57749171180
-
Elucidating rifampin's inducing and inhibiting effects on glyburide pharmacokinetics and blood glucose in healthy volunteers: Unmasking the differential effects of enzyme induction and transporter inhibition for a drug and its primary metabolite
-
Zheng HX, Huang Y, Frassetto LA and Benet LZ (2009) Elucidating rifampin's inducing and inhibiting effects on glyburide pharmacokinetics and blood glucose in healthy volunteers: unmasking the differential effects of enzyme induction and transporter inhibition for a drug and its primary metabolite. Clin Pharmacol Ther 85:78-85.
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 78-85
-
-
Zheng, H.X.1
Huang, Y.2
Frassetto, L.A.3
Benet, L.Z.4
|