Synthesis and biological evaluation of novel oxalamido derivatives as caspase-3 inhibitors

Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry

Volumn 50, Issue 7, 2011, Pages 901-905

  Sengupta, Saumitra ^a   Rao, G Venkateshwar ^a   Dubey, P K ^b  

^a Aurigene Discovery Technologies Limited   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

Author keywords

Apoptosis; Caspase inhibitors; Cysteine proteases; IDN 6556; Peptidomimetic

Indexed keywords

EID: 79959977041     PISSN: 03764699     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Ellis R E, Yuan J & Horvitz H R, Annu Rev Cell Biol, 7, 1991, 663.
2. Nicholson D W, Nature, 407, 2000, 810.
3. Denault J B & Salvesen G S, Chem Rev, 102, 2002, 4489.
4. Livingston D J, J Cell Biochem, 64, 1997, 19.
5. Thornberry N A, Chem Biol, 5, 1998, R97.
6. Talanian R V, Brady K D & Cryns V L, J Med Chem, 43, 2000, 3351.
7. Reed J C, Nat Rev Drug Discov, 1, 2002, 111.
8. Rodriguez I, Matsuura K, Ody C, Nagata S & Vassalli P, J Exp Med, 184, 1996, 2067.
9. White E, Gene Dev, 10, 1996, 1.
10. Ashkenazi A & Dixit V M, Science, 281, 1998, 1305.
11. Dive C & Hickman J A, J Cancer, 64, 1991, 192.
12. Nicholson D W, Ali A, Thornberry N A, Vaillancourt J P, Ding C K, Gallant M, Gareau Y, Griffin P R, Labelle M, Lazebnik Y A, Munday N A, Raju S M, Smulson M E, Yamin T, Yu V L & Miller D R, Nature, 376, 1995, 37.
13. (a) Dolle R E, Hoyer D, Prasad C V, Schmidt S J, Helaszek C T, Miller R E & Ator M A, J Med Chem, 37, 1994, 563
14. (b) Han Y, Giroux A, Grimm E L, Aspiotis R, Francoeur S, Bayly C I, Mckay D J, Roy S, Xanthoudakis S, Vaillancourt J P, Rasper D M, Tam J, Tawa P, Thornberry N A, Paterson E P, Garcia-Calvo M, Becker J W, Rotonda J, Nicholson D W & Zamboni R, Bioorg Med Chem Lett, 14, 2004, 805.
15. Linton S D, Karanewsky D S, Ternansky R J, Wu J C, Pham B, Kodandapani L, Smidt R, Diaz J L, Fritz L C & Tomaselli K, Bioorg Med Chem Lett, 12, 2002, 2969.
16. Karanewsky D S, Bai X, Linton S D, Krebs J F, Wu J, Pham B & Tomaselli K, Bioorg Med Chem Lett, 8, 1998, 2757.
17. Lee D, Long S A, Murray J H, Adams J L, Nuttall M E, Nadeau D P, Kikly K, Winkler J D, Sung C M, Ryan M D, Levy M A, Keller P M & DeWolf W E, J Med Chem, 44, 2001, 2015.
18. Siegmund B & Zeitz M I, Drugs, 6, 2003, 154.
19. Hoglen N C, Chen L S, Fisher C D, Hirakawa B P, Groessl T & Contreras P C, J Pharmacol Exp Ther, 309, 2004, 634.
20. Valentino K L, Gutierrez M, Sanchez R, Winship M J & Shapiro D A, Int J Clin Pharmacol Ther, 41, 2003, 441.
21. Park B K, Kitteringham N R & O'Neill P M, Ann Rev Pharmacol Toxicol, 41, 2000, 443.
22. Linton S D, Aja T, Armstrong R A, Bai X, Chen L S, Chen N, Ching B, Contreras P, Diaz J L, Fisher C D, Fritz L C, Gladstone P, Groessl T, Gu X, Herrmann J, Hirakawa B P, Hoglen N C, Jahangiri K G, Kalish V J, Karanewsky D S, Kodandapani L, Krebs J, McQuiston J, Meduna S P, Nalley K, Robinson E D, Sayers R O, Sebring K, Spada A P, Ternansky R J, Tomaselli K J, Ullman B R, Valentino K L, Weeks S, Winn D & Wu J C, J Med Chem, 48, 2005, 6779.
23. Revesz L, Briswalter C, Heng R, Leutwiler A, Mueller R & Wuethrich H J, Tetrahedron Lett, 35(52), 1994, 9693.
24. Linton S D, Aja T, Allegrini P R, Deckwerth T L, Diaz J L, Hengerer B, Herrmann J, Jahangiri K G, Kallen J, Karanewsky D S, Meduna S P, Nalley K, Robinson E D, Roggo S, Rovelli G, Sauter A, Sayers R O, Schmitz A, Smidt R, Ternansky R J, Tomaselli K J, Ullman B R, Wiessnerb C & Wu J C, Bioorg Med Chem Lett, 14(10), 2004, 2685.