-
2
-
-
33845699846
-
An update on pharmacological approaches to neurodegenerative disease
-
DOI 10.1517/13543784.16.1.59
-
Scatena, R.; Martorana, G. E.; Bottoni, P.; Botta, G.; Pastore, P.; Giardina, B. An update on pharmacological approaches to neurodegenerative diseases. Expert Opin. Investig. Drugs, 2007, 16, 59-72 (Pubitemid 44964167)
-
(2007)
Expert Opinion on Investigational Drugs
, vol.16
, Issue.1
, pp. 59-72
-
-
Scatena, R.1
Martorana, G.E.2
Bottoni, P.3
Botta, G.4
Pastore, P.5
Giardina, B.6
-
3
-
-
41149141053
-
Amyotrophic lateral sclerosis from bench to bedside
-
DOI 10.1055/s-2008-1062265
-
Lomen-Hoerth, C. Amyotrophic lateral sclerosis from bench to bedside. Semin. Neurol., 2008, 28, 205-211 (Pubitemid 351438981)
-
(2008)
Seminars in Neurology
, vol.28
, Issue.2
, pp. 205-211
-
-
Lomen-Hoerth, C.1
-
4
-
-
78649816445
-
Amyotrophic lateral sclerosis: Pathophysiology, diagnosis and management
-
Gordon, P. H. Amyotrophic lateral sclerosis: pathophysiology, diagnosis and management. CNS Drugs, 2011, 25, 1-15
-
(2011)
CNS Drugs
, vol.25
, pp. 1-15
-
-
Gordon, P.H.1
-
5
-
-
0020388782
-
Epidemiology of amyotrophic lateral sclerosis
-
Kurtzke, J. F. Epidemiology of amyotrophic lateral sclerosis. Adv. Neurol., 1982, 36, 281-302
-
(1982)
Adv. Neurol.
, vol.36
, pp. 281-302
-
-
Kurtzke, J.F.1
-
6
-
-
37749020600
-
Descriptive epidemiology of amyotrophic lateral sclerosis: New evidence and unsolved issues
-
Logroscino, G.; Traynor, B. J.; Hardiman, O.; Chio'a, A.; Couratier, P.; Mitchell, J. D.; Swingler, R. J.; Beghi, E. Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues. J. Neurol. Neurosurg. Psychiatry, 2008, 79, 6-11
-
(2008)
J. Neurol. Neurosurg. Psychiatry
, vol.79
, pp. 6-11
-
-
Logroscino, G.1
Traynor, B.J.2
Hardiman, O.3
Chio'a, A.4
Couratier, P.5
Mitchell, J.D.6
Swingler, R.J.7
Beghi, E.8
-
8
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
DOI 10.1038/362059a0
-
Rosen, D. R.; Siddique, T.; Patterson, D.; Figlewicz, D. A.; Sapp, P.; Hentati, A.; Donaldson, D.; Goto, J.; O'Regan, J. P.; Deng, H.-X.; Rahmani, Z.; Krizus, A.; McKenna-Yasek, D.; Cayabyab, A.; Gaston, S. M.; Berger, R.; Tanzi, R. E.; Halperin, J. J.; Herzfeldt, B.; Van den Bergh, R.; Hung, W.-Y.; Bird, T.; Deng, G.; Mulder, D. W.; Smyth, C.; Laing, N. G.; Soriano, E.; Pericak-Vance, M. A.; Haines, J.; Rouleau, G. A.; Gusella, J. S.; Horvitz, H. R.; Brown, R. H. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature, 1993, 362, 59-62 (Pubitemid 23087289)
-
(1993)
Nature
, vol.362
, Issue.6415
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.-X.10
Rahmani, Z.11
Krizus, A.12
McKenna-Yasek, D.13
Cayabyab, A.14
Gaston, S.M.15
Berger, R.16
Tanzi, R.E.17
Halperin, J.J.18
Herzfeldt, B.19
-
9
-
-
79959994298
-
ALS pathogenesis: Recent insights from genetics and mouse models
-
doi:10.1016/j.pnpbp. 2010.1008.1006
-
Swarup, V.; Julien, J.-P. ALS pathogenesis: Recent insights from genetics and mouse models. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2010, doi:10.1016/j.pnpbp. 2010.1008.1006
-
(2010)
Prog. Neuropsychopharmacol. Biol. Psychiatry
-
-
Swarup, V.1
Julien, J.-P.2
-
10
-
-
78649277728
-
Genetic determinants of amyotrophic lateral sclerosis as therapeutic targets
-
Bosco, D. A.; Landers, J. E. Genetic determinants of amyotrophic lateral sclerosis as therapeutic targets. CNS Neurol. Disord. Drug Targets, 2010, 9, 779-790
-
(2010)
CNS Neurol. Disord. Drug Targets
, vol.9
, pp. 779-790
-
-
Bosco, D.A.1
Landers, J.E.2
-
11
-
-
79953210757
-
Identification of a FUS splicing mutation in a large family with amyotrophic lateral sclerosis
-
doi:10.1038/jhg.2010.1162
-
Belzil, V. V.; St-Onge, J.; Daoud, H.; Desjarlais, A.; Bouchard, J.-P.; Dupre, N.; Camu, W.; Dion, P. A.; Rouleau, G. A. Identification of a FUS splicing mutation in a large family with amyotrophic lateral sclerosis. J. Hum. Genet., 2010, doi:10.1038/jhg.2010.1162
-
(2010)
J. Hum. Genet.
-
-
Belzil, V.V.1
St-Onge, J.2
Daoud, H.3
Desjarlais, A.4
Bouchard, J.-P.5
Dupre, N.6
Camu, W.7
Dion, P.A.8
Rouleau, G.A.9
-
12
-
-
78349241067
-
Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: Diseaseassociated pathways
-
Barmada, S. J.; Finkbeiner, S. Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: diseaseassociated pathways. Rev. Neurosci., 2010, 21, 251-272
-
(2010)
Rev. Neurosci.
, vol.21
, pp. 251-272
-
-
Barmada, S.J.1
Finkbeiner, S.2
-
14
-
-
77956850818
-
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
-
Mackenzie, I. R.; Rademakers, R.; Neumann, M. TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol., 2010, 9, 995-1007
-
(2010)
Lancet Neurol.
, vol.9
, pp. 995-1007
-
-
Mackenzie, I.R.1
Rademakers, R.2
Neumann, M.3
-
15
-
-
33745223900
-
Amyotrophic lateral sclerosis (motor neuron disease): Proposed mechanisms and pathways to treatment
-
DOI 10.1111/j.1467-9639.2006.00001.x, PII S1462399406010854
-
Goodall, E. F.; Morrison, K. E. Amyotrophic lateral sclerosis (motor neuron disease): proposed mechanisms and pathways to treatment. Expert Rev. Mol. Med., 2006, 8, 1-22 (Pubitemid 43904876)
-
(2006)
Expert Reviews in Molecular Medicine
, vol.8
, Issue.11
, pp. 1-22
-
-
Goodall, E.F.1
Morrison, K.E.2
-
16
-
-
60849093466
-
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
-
Rothstein, J. D. Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann. Neurol., 2009, 65, S3-S9
-
(2009)
Ann. Neurol.
, vol.65
-
-
Rothstein, J.D.1
-
17
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
DOI 10.1146/annurev.neuro.27.070203.144244
-
Bruijn, L. I.; Miller, T. M.; Cleveland, D. W. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Ann. Rev. Neurosci., 2004, 27, 723-749 (Pubitemid 39050419)
-
(2004)
Annual Review of Neuroscience
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
18
-
-
77953503937
-
Riluzole, neuroprotection and amyotrophic lateral sclerosis
-
Cheah, B. C.; Vucic, S.; Krishnan, A. V.; Kiernan, M. C. Riluzole, neuroprotection and amyotrophic lateral sclerosis. Curr. Med. Chem., 2010, 17, 1942-1199
-
(2010)
Curr. Med. Chem.
, vol.17
, pp. 1942-1199
-
-
Cheah, B.C.1
Vucic, S.2
Krishnan, A.V.3
Kiernan, M.C.4
-
19
-
-
70449721890
-
Current and emerging treatments for amyotrophic lateral sclerosis
-
Zoccolella, S.; Santamato, A.; Lamberti, P. Current and emerging treatments for amyotrophic lateral sclerosis. Neuropsychiatr. Dis. Treat., 2009, 5, 577-595
-
(2009)
Neuropsychiatr. Dis. Treat.
, vol.5
, pp. 577-595
-
-
Zoccolella, S.1
Santamato, A.2
Lamberti, P.3
-
20
-
-
79551512488
-
Research advances in amyotrophic lateral sclerosis, 2009 to 2010
-
Traub, R.; Mitsumoto, H.; Rowland, L. P. Research advances in amyotrophic lateral sclerosis, 2009 to 2010. Curr. Neurol. Neurosci. Rep., 2011, 11, 67-77
-
(2011)
Curr. Neurol. Neurosci. Rep.
, vol.11
, pp. 67-77
-
-
Traub, R.1
Mitsumoto, H.2
Rowland, L.P.3
-
21
-
-
77954344953
-
Clinical trials for neuroprotection in ALS
-
Siciliano, G.; Carlesi, C.; Pasquali, L.; Piazza, S.; Pietracupa, S.; Fornai, F.; Ruggieri, S.; Murri, L. Clinical trials for neuroprotection in ALS. CNS Neurol. Disord. Drug Targets, 2010, 9, 305-313
-
(2010)
CNS Neurol. Disord. Drug Targets
, vol.9
, pp. 305-313
-
-
Siciliano, G.1
Carlesi, C.2
Pasquali, L.3
Piazza, S.4
Pietracupa, S.5
Fornai, F.6
Ruggieri, S.7
Murri, L.8
-
22
-
-
0032728304
-
Experimental models of amyotrophic lateral sclerosis
-
DOI 10.1006/nbdi.1999.0266
-
Elliott, J. L. Experimental models of amyotrophic lateral sclerosis. Neurobiol. Dis., 1999, 6, 310-320 (Pubitemid 29496211)
-
(1999)
Neurobiology of Disease
, vol.6
, Issue.5
, pp. 310-320
-
-
Elliott, J.L.1
-
23
-
-
79951674097
-
Transgenic animal models of neurodegeneration based on human genetic studies
-
Harvey, B. K.; Richie, C. T.; Hoffer, B. J.; Airavaara, M. Transgenic animal models of neurodegeneration based on human genetic studies. J. Neural. Transm., 2011, 118, 27-45
-
(2011)
J. Neural. Transm.
, vol.118
, pp. 27-45
-
-
Harvey, B.K.1
Richie, C.T.2
Hoffer, B.J.3
Airavaara, M.4
-
24
-
-
36949019768
-
Amyotrophic lateral sclerosis models and human neuropathology: Similarities and differences
-
DOI 10.1007/s00401-007-0308-4
-
Kato, S. Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences. Acta Neuropathol., 2008, 115, 97-114 (Pubitemid 50003823)
-
(2008)
Acta Neuropathologica
, vol.115
, Issue.1
, pp. 97-114
-
-
Kato, S.1
-
25
-
-
79951754463
-
Effect of genetic background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: A window of opportunity in the search for genetic modifiers
-
doi: 10.3109/17482968.17482010.17550626
-
Heiman-Patterson, T. D.; Sher, R. B.; Blankenhorn, E. A.; Alexander, G.; Deitch, J. S.; Kunst, C. B.; Maragakis, N.; Cox, G. Effect of genetic background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: A window of opportunity in the search for genetic modifiers. Amyotroph. Lateral Scler., 2011, doi: 10.3109/17482968.17482010.17550626
-
(2011)
Amyotroph. Lateral Scler.
-
-
Heiman-Patterson, T.D.1
Sher, R.B.2
Blankenhorn, E.A.3
Alexander, G.4
Deitch, J.S.5
Kunst, C.B.6
Maragakis, N.7
Cox, G.8
-
26
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
-
Gurney, M. E.; Pu, H.; Chiu, A. Y.; Dal Canto, M. C.; Polchow, C. Y.; Alexander, D. D.; Caliendo, J.; Hentati, A.; Kwon, Y. W.; Deng, H. X.; Chen, W. J.; Zhai, P.; Sufit, R. L.; Siddique, T. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science, 1994, 264, 1772-1775 (Pubitemid 24227760)
-
(1994)
Science
, vol.264
, Issue.5166
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.-X.10
Chen, W.11
Zhai, P.12
Sufit, R.L.13
Siddique, T.14
-
27
-
-
33947323759
-
Lost in translation: Treatment trials in the SOD1 mouse and in human ALS
-
DOI 10.1016/j.nbd.2006.12.015, PII S0969996106003287
-
Benatar, M. Lost in translation: treatment trials in the SOD1 mouse and in human ALS. Neurobiol. Dis., 2007, 26, 1-13 (Pubitemid 46437445)
-
(2007)
Neurobiology of Disease
, vol.26
, Issue.1
, pp. 1-13
-
-
Benatar, M.1
-
28
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
DOI 10.1126/science.1134108
-
Neumann, M.; Sampathu, D. M.; Kwong, L. K.; Truax, A. C.; Micsenyi, M. C.; Chou, T. T.; Bruce, J.; Schuck, T.; Grossman, M.; Clark, C. M.; McCluskey, L. F.; Miller, B. L.; Masliah, E.; Mackenzie, I. R.; Feldman, H.; Feiden, W.; Kretzschmar, H. A.; Trojanowski, J. Q.; Lee, V. M. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science, 2006, 314, 130-133 (Pubitemid 44547757)
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.-Y.19
-
29
-
-
79955812764
-
TDP-43-Based Animal Models of Neurodegeneration: New Insights into ALS Pathology and Pathophysiology
-
doi: 10.1159/000321547
-
Wegorzewska, I.; Baloh, R. H. TDP-43-Based Animal Models of Neurodegeneration: New Insights into ALS Pathology and Pathophysiology. Neurodegener. Dis., 2011, doi: 10.1159/000321547
-
(2011)
Neurodegener. Dis.
-
-
Wegorzewska, I.1
Baloh, R.H.2
-
30
-
-
73249152831
-
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
-
Wegorzewska, I.; Bell, S.; Cairns, N. J.; Miller, T. M.; Baloh, R. H. TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proc. Natl. Acad. Sci. USA, 2009, 106, 18809-18814
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 18809-18814
-
-
Wegorzewska, I.1
Bell, S.2
Cairns, N.J.3
Miller, T.M.4
Baloh, R.H.5
-
31
-
-
77649269011
-
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
-
Wils, H.; Kleinberger, G.; Janssens, J.; Pereson, S.; Joris, G.; Cuijt, I.; Smits, V.; Ceuterick-de Groote, C.; Van Broeckhoven, C.; Kumar-Singh, S. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc. Natl. Acad. Sci. USA, 2010, 107, 3858-3863
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 3858-3863
-
-
Wils, H.1
Kleinberger, G.2
Janssens, J.3
Pereson, S.4
Joris, G.5
Cuijt, I.6
Smits, V.7
Groote, C.-D.C.8
Van Broeckhoven, C.9
Kumar-Singh, S.10
-
32
-
-
79251518539
-
Progressive motor weakness in transgenic mice expressing human TDP-43
-
Stallings, N. R.; Puttaparthi, K.; Luther, C. M.; Burns, D. K.; Elliott, J. L. Progressive motor weakness in transgenic mice expressing human TDP-43. Neurobiol. Dis., 2010, 40, 404-414
-
(2010)
Neurobiol. Dis.
, vol.40
, pp. 404-414
-
-
Stallings, N.R.1
Puttaparthi, K.2
Luther, C.M.3
Burns, D.K.4
Elliott, J.L.5
-
33
-
-
77955395385
-
Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U
-
Tsai, K. J.; Yang, C. H.; Fang, Y. H.; Cho, K. H.; Chien, W. L.; Wang, W. T.; Wu, T. W.; Lin, C. P.; Fu, W. M.; Shen, C. K. Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U. J. Exp. Med., 2010, 207, 1661-1673
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1661-1673
-
-
Tsai, K.J.1
Yang, C.H.2
Fang, Y.H.3
Cho, K.H.4
Chien, W.L.5
Wang, W.T.6
Wu, T.W.7
Lin, C.P.8
Fu, W.M.9
Shen, C.K.10
-
34
-
-
77956199371
-
Wildtype human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice
-
Xu, Y. F.; Gendron, T. F.; Zhang, Y. J.; Lin, W. L.; D'Alton, S.; Sheng, H.; Casey, M. C.; Tong, J.; Knight, J.; Yu, X.; Rademakers, R.; Boylan, K.; Hutton, M.; McGowan, E.; Dickson, D. W.; Lewis, J.; Petrucelli, L. Wildtype human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J. Neurosci., 2010, 30, 10851-10859
-
(2010)
J. Neurosci.
, vol.30
, pp. 10851-10859
-
-
Xu, Y.F.1
Gendron, T.F.2
Zhang, Y.J.3
Lin, W.L.4
D'Alton, S.5
Sheng, H.6
Casey, M.C.7
Tong, J.8
Knight, J.9
Yu, X.10
Rademakers, R.11
Boylan, K.12
Hutton, M.13
McGowan, E.14
Dickson, D.W.15
Lewis, J.16
Petrucelli, L.17
-
35
-
-
77958022745
-
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
-
Shan, X.; Chiang, P. M.; Price, D. L.; Wong, P. C. Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc. Natl. Acad. Sci. USA, 2010, 107, 16325-16330
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 16325-16330
-
-
Shan, X.1
Chiang, P.M.2
Price, D.L.3
Wong, P.C.4
-
36
-
-
77954653461
-
Neurotoxic effects of TDP-43 overexpression in C. elegans
-
Ash, P. E.; Zhang, Y. J.; Roberts, C. M.; Saldi, T.; Hutter, H.; Buratti, E.; Petrucelli, L.; Link, C. D. Neurotoxic effects of TDP-43 overexpression in C. elegans. Hum. Mol. Genet., 2010, 19, 3206-3218
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3206-3218
-
-
Ash, P.E.1
Zhang, Y.J.2
Roberts, C.M.3
Saldi, T.4
Hutter, H.5
Buratti, E.6
Petrucelli, L.7
Link, C.D.8
-
37
-
-
77649258646
-
A Drosophila model for TDP-43 proteinopathy
-
Li, Y.; Ray, P.; Rao, E. J.; Shi, C.; Guo, W.; Chen, X.; Woodruff, E. A., 3rd; Fushimi, K.; Wu, J. Y. A Drosophila model for TDP-43 proteinopathy. Proc. Natl. Acad. Sci. USA, 2010, 107, 3169-3174
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 3169-3174
-
-
Li, Y.1
Ray, P.2
Rao, E.J.3
Shi, C.4
Guo, W.5
Chen, X.6
Woodruff III, E.A.7
Fushimi, K.8
Wu, J.Y.9
-
38
-
-
77951236534
-
Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS)
-
Hanson, K. A.; Kim, S. H.; Wassarman, D. A.; Tibbetts, R. S. Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS). J. Biol. Chem., 2010, 285, 11068-11072
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 11068-11072
-
-
Hanson, K.A.1
Kim, S.H.2
Wassarman, D.A.3
Tibbetts, R.S.4
-
39
-
-
77953194507
-
TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97
-
Ritson, G. P.; Custer, S. K.; Freibaum, B. D.; Guinto, J. B.; Geffel, D.; Moore, J.; Tang, W.; Winton, M. J.; Neumann, M.; Trojanowski, J. Q.; Lee, V. M.; Forman, M. S.; Taylor, J. P. TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97. J. Neurosci., 2010, 30, 7729-7739
-
(2010)
J. Neurosci.
, vol.30
, pp. 7729-7739
-
-
Ritson, G.P.1
Custer, S.K.2
Freibaum, B.D.3
Guinto, J.B.4
Geffel, D.5
Moore, J.6
Tang, W.7
Winton, M.J.8
Neumann, M.9
Trojanowski, J.Q.10
Lee, V.M.11
Forman, M.S.12
Taylor, J.P.13
-
40
-
-
4644350389
-
Occurrence of β-methylamino-L-alanine (BMAA) in. ALS/PDC patients from Guam
-
DOI 10.1111/j.1600-0404.2004.00320.x
-
Murch, S. J.; Cox, P. A.; Banack, S. A.; Steele, J. C.; Sacks, O. W. Occurrence of beta-methylamino-l-alanine (BMAA) in ALS/PDC patients from Guam. Acta Neurol. Scand., 2004, 110, 267-269 (Pubitemid 39274063)
-
(2004)
Acta Neurologica Scandinavica
, vol.110
, Issue.4
, pp. 267-269
-
-
Murch, S.J.1
Cox, P.A.2
Banack, S.A.3
Steele, J.C.4
Sacks, O.W.5
-
41
-
-
74549160247
-
Cyanobacteria and BMAA exposure from desert dust: A possible link to sporadic ALS among Gulf War veterans
-
Cox, P. A.; Richer, R.; Metcalf, J. S.; Banack, S. A.; Codd, G. A.; Bradley, W. G. Cyanobacteria and BMAA exposure from desert dust: a possible link to sporadic ALS among Gulf War veterans. Amyotroph. Lateral Scler., 2009, 10 Suppl 2, 109-117
-
(2009)
Amyotroph. Lateral Scler.
, vol.10
, Issue.2 SUPPL.
, pp. 109-117
-
-
Cox, P.A.1
Richer, R.2
Metcalf, J.S.3
Banack, S.A.4
Codd, G.A.5
Bradley, W.G.6
-
42
-
-
38349089902
-
Animal models of BMAA neurotoxicity: A critical review
-
Karamyan, V. T.; Speth, R. C. Animal models of BMAA neurotoxicity: a critical review. Life Sci., 2008, 82, 233-246
-
(2008)
Life Sci.
, vol.82
, pp. 233-246
-
-
Karamyan, V.T.1
Speth, R.C.2
-
43
-
-
74549115178
-
BMAA neurotoxicity in Drosophila
-
Zhou, X.; Escala, W.; Papapetropoulos, S.; Bradley, W. G.; Zhai, R. G. BMAA neurotoxicity in Drosophila. Amyotroph. Lateral Scler., 2009, 10 Suppl 2, 61-66
-
(2009)
Amyotroph. Lateral Scler.
, vol.10
, Issue.2 SUPPL.
, pp. 61-66
-
-
Zhou, X.1
Escala, W.2
Papapetropoulos, S.3
Bradley, W.G.4
Zhai, R.G.5
-
44
-
-
33751560981
-
A nonprotein amino acid and neurodegeneration
-
Cox, P. A.; Banack, S. A. A nonprotein amino acid and neurodegeneration. Science, 2006, 314, 1242
-
(2006)
Science
, vol.314
, pp. 1242
-
-
Cox, P.A.1
Banack, S.A.2
-
45
-
-
0034730573
-
Motor neuron disease in vitro: The use of cultured motor neurons to study amyotrophic lateral sclerosis
-
Bär, P. R. Motor neuron disease in vitro: the use of cultured motor neurons to study amyotrophic lateral sclerosis. Eur. J. Pharmacol., 2000, 405, 285-295
-
(2000)
Eur. J. Pharmacol.
, vol.405
, pp. 285-295
-
-
Bär, P.R.1
-
46
-
-
45549087576
-
Models of amyotrophic lateral sclerosis
-
Unit 9 13
-
Jackson, M.; Ganel, R.; Rothstein, J. D. Models of amyotrophic lateral sclerosis. Curr. Protoc. Neurosci., 2002, Chapter 9, Unit 9 13
-
(2002)
Curr. Protoc. Neurosci.
, pp. 9
-
-
Jackson, M.1
Ganel, R.2
Rothstein, J.D.3
-
47
-
-
1542543458
-
Edaravone, a newly developed radical scavenger, protects against ischemia-reperfusion injury of the small intestine in rats
-
Tomatsuri, N.; Yoshida, N.; Takagi, T.; Katada, K.; Isozaki, Y.; Imamoto, E.; Uchiyama, K.; Kokura, S.; Ichikawa, H.; Naito, Y.; Okanoue, T.; Yoshikawa, T. Edaravone, a newly developed radical scavenger, protects against ischemia-reperfusion injury of the small intestine in rats. Int. J. Mol. Med., 2004, 13, 105-109
-
(2004)
Int. J. Mol. Med.
, vol.13
, pp. 105-109
-
-
Tomatsuri, N.1
Yoshida, N.2
Takagi, T.3
Katada, K.4
Isozaki, Y.5
Imamoto, E.6
Uchiyama, K.7
Kokura, S.8
Ichikawa, H.9
Naito, Y.10
Okanoue, T.11
Yoshikawa, T.12
-
48
-
-
19944428649
-
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
-
DOI 10.1038/nature03180
-
Rothstein, J. D.; Patel, S.; Regan, M. R.; Haenggeli, C.; Huang, Y. H.; Bergles, D. E.; Jin, L.; Dykes Hoberg, M.; Vidensky, S.; Chung, D. S.; Toan, S. V.; Bruijn, L. I.; Su, Z. Z.; Gupta, P.; Fisher, P. B. Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. Nature, 2005, 433, 73-77 (Pubitemid 40101145)
-
(2005)
Nature
, vol.433
, Issue.7021
, pp. 73-77
-
-
Rothstein, J.D.1
Patel, S.2
Regan, M.R.3
Haenggeli, C.4
Huang, Y.H.5
Bergles, D.E.6
Jin, L.7
Hoberg, M.D.8
Vidensky, S.9
Chung, D.S.10
Shuy, V.T.11
Bruijn, L.I.12
Su, Z.-Z.13
Gupta, P.14
Fisher, P.B.15
-
49
-
-
79959951540
-
-
http://www.knoppneurosciences.com
-
-
-
-
50
-
-
77955358107
-
Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis
-
Martin, L. J. Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis. IDrugs, 2010, 13, 568-580
-
(2010)
IDrugs
, vol.13
, pp. 568-580
-
-
Martin, L.J.1
-
51
-
-
77954106884
-
Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis
-
Phukan, J. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis. IDrugs, 2010, 13, 482-496
-
(2010)
IDrugs
, vol.13
, pp. 482-496
-
-
Phukan, J.1
-
52
-
-
79959991547
-
-
Clinical trial NCT00561366
-
www.clinicaltrials.gov (Clinical trial NCT00561366)
-
-
-
-
53
-
-
79959939733
-
-
Clinical trial NCT01083667
-
www.clinicaltrials.gov (Clinical trial NCT01083667)
-
-
-
-
54
-
-
77950941205
-
GSK3beta: Role in therapeutic landscape and development of modulators
-
Phukan, S.; Babu, V. S.; Kannoji, A.; Hariharan, R.; Balaji, V. N. GSK3beta: role in therapeutic landscape and development of modulators. Br. J. Pharmacol., 2010, 160, 1-19
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 1-19
-
-
Phukan, S.1
Babu, V.S.2
Kannoji, A.3
Hariharan, R.4
Balaji, V.N.5
-
55
-
-
39849110726
-
The GSK3 hypothesis of Alzheimer's disease
-
DOI 10.1111/j.1471-4159.2007.05194.x
-
Hooper, C.; Killick, R.; Lovestone, S. The GSK3 hypothesis of Alzheimer's disease. J. Neurochem., 2008, 104, 1433-1439 (Pubitemid 351316776)
-
(2008)
Journal of Neurochemistry
, vol.104
, Issue.6
, pp. 1433-1439
-
-
Hooper, C.1
Killick, R.2
Lovestone, S.3
-
56
-
-
50249112166
-
Preclinical efficacy on GSK-3 inhibitors: Towards a future generation of powerful drugs
-
Martinez, A. Preclinical efficacy on GSK-3 inhibitors: towards a future generation of powerful drugs. Med. Res. Rev., 2008, 28, 773-796
-
(2008)
Med. Res. Rev.
, vol.28
, pp. 773-796
-
-
Martinez, A.1
-
57
-
-
54249140068
-
GSK-3 inhibitors: A ray of hope for the treatment of Alzheimer's disease?
-
Martinez, A.; Perez, D. I. GSK-3 inhibitors: a ray of hope for the treatment of Alzheimer's disease? J. Alzheimers Dis., 2008, 15, 181-191
-
(2008)
J. Alzheimers Dis.
, vol.15
, pp. 181-191
-
-
Martinez, A.1
Perez, D.I.2
-
58
-
-
63849147445
-
GSK-3 inhibitors and insulin receptor signaling in health, disease, and therapeutics
-
Wada, A. GSK-3 inhibitors and insulin receptor signaling in health, disease, and therapeutics. Front. Biosci., 2009, 14, 1558-1570
-
(2009)
Front. Biosci.
, vol.14
, pp. 1558-1570
-
-
Wada, A.1
-
59
-
-
50249188313
-
-
Martinez, A., Castro, A. and Medina, M. Eds., Ed.; John Wiley & Sons: Hoboken, New Jersey
-
Jope, R. S. In: Glycogen synthase kinase 3 (GSK-3) and its inhibitors. Martinez, A., Castro, A. and Medina, M. Eds., Ed.; John Wiley & Sons: Hoboken, New Jersey, 2006, pp. 223-242.
-
(2006)
Glycogen Synthase Kinase 3 (GSK-3) and its Inhibitors
, pp. 223-242
-
-
Jope, R.S.1
-
60
-
-
1642286981
-
GSK-3 inhibitors: Discoveries and developments
-
DOI 10.2174/0929867043455738
-
Alonso, M.; Martinez, A. GSK-3 inhibitors: discoveries and developments. Curr. Med. Chem., 2004, 11, 755-763 (Pubitemid 38380049)
-
(2004)
Current Medicinal Chemistry
, vol.11
, Issue.6
, pp. 755-763
-
-
Alonso, M.1
Martinez, A.2
-
61
-
-
35348906081
-
Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease
-
DOI 10.1021/np060092r
-
Hamann, M.; Alonso, D.; Martin-Aparicio, E.; Fuertes, A.; Perez-Puerto, M. J.; Castro, A.; Morales, S.; Navarro, M. L.; Del Monte-Millan, M.; Medina, M.; Pennaka, H.; Balaiah, A.; Peng, J.; Cook, J.; Wahyuono, S.; Martinez, A. Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease. J. Nat. Prod., 2007, 70, 1397-1405 (Pubitemid 47584577)
-
(2007)
Journal of Natural Products
, vol.70
, Issue.9
, pp. 1397-1405
-
-
Hamann, M.1
Alonso, D.2
Martin-Aparicio, E.3
Fuertes, A.4
Perez-Puerto, M.J.5
Castro, A.6
Morales, S.7
Navarro, M.L.8
Del Monte-Millan, M.9
Medina, M.10
Pennaka, H.11
Balaiah, A.12
Peng, J.13
Cook, J.14
Wahyuono, S.15
Martinez, A.16
-
62
-
-
79951673475
-
-
Martinez, A., Castro, A. and Medina, M. Eds., Ed.; John Wiley & Sons: Hoboken, New Jersey
-
Alonso, D.; Martinez, A. In: Glycogen synthase kinase 3 (GSK-3) and its inhibitors. Martinez, A., Castro, A. and Medina, M. Eds., Ed.; John Wiley & Sons: Hoboken, New Jersey, 2006, pp. 307-331.
-
(2006)
Glycogen Synthase Kinase 3 (GSK-3) and its Inhibitors
, pp. 307-331
-
-
Alonso, D.1
Martinez, A.2
-
63
-
-
33845302976
-
Peptides targeting protein kinases: Strategies and implications
-
DOI 10.1152/physiol.00022.2006
-
Kaidanovich-Beilin, O.; Eldar-Finkelman, H. Peptides targeting protein kinases: strategies and implications. Physiology, 2006, 21, 411-418 (Pubitemid 44879250)
-
(2006)
Physiology
, vol.21
, Issue.6
, pp. 411-418
-
-
Kaidanovich-Beilin, O.1
Eldar-Finkelman, H.2
-
64
-
-
59649119743
-
Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3
-
Atilla-Gokcumen, G. E.; Pagano, N.; Streu, C.; Maksimoska, J.; Filippakopoulos, P.; Knapp, S.; Meggers, E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. ChemBioChem, 2008, 9, 2933-2936
-
(2008)
ChemBioChem
, vol.9
, pp. 2933-2936
-
-
Atilla-Gokcumen, G.E.1
Pagano, N.2
Streu, C.3
Maksimoska, J.4
Filippakopoulos, P.5
Knapp, S.6
Meggers, E.7
-
65
-
-
69949132072
-
-
Martinez, A. E., Ed.; Martinez, A. Ed. Transworld Research Network: Kerala
-
Martinez, A.; Alonso, M.; Castro, A.; Dorronsoro, I. In: In Medicinal Chemistry of Alzheimer's disease. Martinez, A. E., Ed.; Martinez, A. Ed. Transworld Research Network: Kerala, 2008, pp. 225-253.
-
(2008)
Medicinal Chemistry of Alzheimer's Disease
, pp. 225-253
-
-
Martinez, A.1
Alonso, M.2
Castro, A.3
Dorronsoro, I.4
-
66
-
-
79959476224
-
Switching reversibility to irreversibility in GSK-3 inhibitors: Clues for specific design of new compounds
-
doi. 10.1021/jm1016279
-
Pérez, D. I.; Palomo, V.; Pérez, C.; Gil, C.; Dans, P.; Luque, F. J.; Conde, S.; Martinez, A. Switching reversibility to irreversibility in GSK-3 inhibitors: clues for specific design of new compounds. J. Med. Chem., 2011, doi. 10.1021/jm1016279
-
(2011)
J. Med. Chem.
-
-
Pérez, D.I.1
Palomo, V.2
Pérez, C.3
Gil, C.4
Dans, P.5
Luque, F.J.6
Conde, S.7
Martinez, A.8
-
67
-
-
0345184327
-
Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord
-
Hu, J. H.; Zhang, H.; Wagey, R.; Krieger, C.; Pelech, S. L. Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord. J. Neurochem., 2003, 85, 432-442 (Pubitemid 36438338)
-
(2003)
Journal of Neurochemistry
, vol.85
, Issue.2
, pp. 432-442
-
-
Hu, J.-H.1
Zhang, H.2
Wagey, R.3
Krieger, C.4
Pelech, S.L.5
-
68
-
-
39149141844
-
Upregulation of GSK3beta expression in frontal and temporal cortex in ALS with cognitive impairment (ALSci)
-
Yang, W.; Leystra-Lantz, C.; Strong, M. J. Upregulation of GSK3beta expression in frontal and temporal cortex in ALS with cognitive impairment (ALSci). Brain Res., 2008, 1196, 131-139
-
(2008)
Brain Res.
, vol.1196
, pp. 131-139
-
-
Yang, W.1
Leystra-Lantz, C.2
Strong, M.J.3
-
69
-
-
70349309705
-
Immunohistochemical expression of IGF-I and GSK in the spinal cord of Kii and Guamanian ALS patients
-
Kihira, T.; Suzuki, A.; Kondo, T.; Wakayama, I.; Yoshida, S.; Hasegawa, K.; Garruto, R. M. Immunohistochemical expression of IGF-I and GSK in the spinal cord of Kii and Guamanian ALS patients. Neuropathology, 2009, 29, 548-558
-
(2009)
Neuropathology
, vol.29
, pp. 548-558
-
-
Kihira, T.1
Suzuki, A.2
Kondo, T.3
Wakayama, I.4
Yoshida, S.5
Hasegawa, K.6
Garruto, R.M.7
-
70
-
-
4444356826
-
Epigallocatechin gallate prevents oxidative-stress-induced death of mutant Cu/Zn-superoxide dismutase (G93A) motoneuron cells by alteration of cell survival and death signals
-
DOI 10.1016/j.tox.2004.05.008, PII S0300483X04002963
-
Koh, S. H.; Kwon, H.; Kim, K. S.; Kim, J.; Kim, M. H.; Yu, H. J.; Kim, M.; Lee, K. W.; Do, B. R.; Jung, H. K.; Yang, K. W.; Appel, S. H.; Kim, S. H. Epigallocatechin gallate prevents oxidative-stress-induced death of mutant Cu/Zn-superoxide dismutase (G93A) motoneuron cells by alteration of cell survival and death signals. Toxicology, 2004, 202, 213-225 (Pubitemid 39165396)
-
(2004)
Toxicology
, vol.202
, Issue.3
, pp. 213-225
-
-
Koh, S.-H.1
Kwon, H.2
Kim, K.S.3
Kim, J.4
Kim, M.-H.5
Yu, H.-J.6
Kim, M.7
Lee, K.-W.8
Do, B.R.9
Jung, H.K.10
Yang, K.-W.11
Appel, S.H.12
Kim, S.H.13
-
71
-
-
23244436178
-
Role of GSK-3β activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene
-
DOI 10.1111/j.1460-9568.2005.04191.x
-
Koh, S. H.; Lee, Y. B.; Kim, K. S.; Kim, H. J.; Kim, M.; Lee, Y. J.; Kim, J.; Lee, K. W.; Kim, S. H. Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene. Eur. J. Neurosci., 2005, 22, 301-309 (Pubitemid 41097603)
-
(2005)
European Journal of Neuroscience
, vol.22
, Issue.2
, pp. 301-309
-
-
Koh, S.-H.1
Lee, Y.-B.2
Kim, K.S.3
Kim, H.-J.4
Kim, M.5
Lee, Y.J.6
Kim, J.7
Lee, K.W.8
Kim, S.H.9
-
72
-
-
57349106488
-
Immunohistochemical study on the distribution of glycogen synthase kinase 3alpha in the central nervous system of SOD1 (G93A) transgenic mice
-
Chung, Y. H.; Joo, K. M.; Kim, D. J.; Kim, S. S.; Kim, K. Y.; Lee, W. B.; Cha, C. I. Immunohistochemical study on the distribution of glycogen synthase kinase 3alpha in the central nervous system of SOD1 (G93A) transgenic mice. Neurol. Res., 2008, 30, 926-931
-
(2008)
Neurol. Res.
, vol.30
, pp. 926-931
-
-
Chung, Y.H.1
Joo, K.M.2
Kim, D.J.3
Kim, S.S.4
Kim, K.Y.5
Lee, W.B.6
Cha, C.I.7
-
73
-
-
34548012115
-
GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder
-
DOI 10.1016/j.neubiorev.2007.03.002, PII S0149763407000243
-
Rowe, M. K.; Wiest, C.; Chuang, D. M. GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder. Neurosci. Biobehav. Rev., 2007, 31, 920-931 (Pubitemid 47285347)
-
(2007)
Neuroscience and Biobehavioral Reviews
, vol.31
, Issue.6
, pp. 920-931
-
-
Rowe, M.K.1
Wiest, C.2
Chuang, D.-M.3
-
74
-
-
0030449964
-
Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
-
Stambolic, V.; Ruel, L.; Woodgett, J. R. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr. Biol., 1996, 6, 1664-1668 (Pubitemid 27050234)
-
(1996)
Current Biology
, vol.6
, Issue.12
, pp. 1664-1668
-
-
Stambolic, V.1
Ruel, L.2
Woodgett, J.R.3
-
75
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
DOI 10.1073/pnas.93.16.8455
-
Klein, P. S.; Melton, D. A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. USA, 1996, 93, 8455-8459 (Pubitemid 26269579)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.16
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
76
-
-
0036909443
-
Regulation of Akt and glycogen synthase kinase-3β phosphorylation by sodium valproate and lithium
-
DOI 10.1016/S0028-3908(02)00215-0
-
De Sarno, P.; Li, X.; Jope, R. S. Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium. Neuropharmacology, 2002, 43, 1158-1164 (Pubitemid 36009369)
-
(2002)
Neuropharmacology
, vol.43
, Issue.7
, pp. 1158-1164
-
-
De Sarno, P.1
Li, X.2
Jope, R.S.3
-
77
-
-
10844284615
-
Benefit of valproic acid in suppressing disease progression of ALS model mice
-
DOI 10.1111/j.1460-9568.2004.03765.x
-
Sugai, F.; Yamamoto, Y.; Miyaguchi, K.; Zhou, Z.; Sumi, H.; Hamasaki, T.; Goto, M.; Sakoda, S. Benefit of valproic acid in suppressing disease progression of ALS model mice. Eur. J. Neurosci., 2004, 20, 3179-3183 (Pubitemid 40007312)
-
(2004)
European Journal of Neuroscience
, vol.20
, Issue.11
, pp. 3179-3183
-
-
Sugai, F.1
Yamamoto, Y.2
Miyaguchi, K.3
Zhou, Z.4
Sumi, H.5
Hamasaki, T.6
Goto, M.7
Sakoda, S.8
-
78
-
-
33947363215
-
Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis
-
Shin, J. H.; Cho, S. I.; Lim, H. R.; Lee, J. K.; Lee, Y. A.; Noh, J. S.; Joo, I. S.; Kim, K. W.; Gwag, B. J. Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis. Mol. Pharmacol., 2007, 71, 965-975
-
(2007)
Mol. Pharmacol.
, vol.71
, pp. 965-975
-
-
Shin, J.H.1
Cho, S.I.2
Lim, H.R.3
Lee, J.K.4
Lee, Y.A.5
Noh, J.S.6
Joo, I.S.7
Kim, K.W.8
Gwag, B.J.9
-
79
-
-
74149092630
-
Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord
-
Calderó, J.; Brunet, N.; Tarabal, O.; Piedrafita, L.; Hereu, M.; Ayala, V.; Esquerda, J. E. Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord. Neuroscience, 2010, 165, 1353-1369
-
(2010)
Neuroscience
, vol.165
, pp. 1353-1369
-
-
Calderó, J.1
Brunet, N.2
Tarabal, O.3
Piedrafita, L.4
Hereu, M.5
Ayala, V.6
Esquerda, J.E.7
-
80
-
-
49249136687
-
Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model
-
Feng, H. L.; Leng, Y.; Ma, C. H.; Zhang, J.; Ren, M.; Chuang, D. M. Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model. Neuroscience, 2008, 155, 567-572
-
(2008)
Neuroscience
, vol.155
, pp. 567-572
-
-
Feng, H.L.1
Leng, Y.2
Ma, C.H.3
Zhang, J.4
Ren, M.5
Chuang, D.M.6
-
81
-
-
40449135649
-
Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: Roles of glycogen synthase kinase-3 inhibition
-
DOI 10.1523/JNEUROSCI.5467-07.2008
-
Leng, Y.; Liang, M. H.; Ren, M.; Marinova, Z.; Leeds, P.; Chuang, D. M. Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition. J. Neurosci., 2008, 28, 2576-2588 (Pubitemid 351348211)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.10
, pp. 2576-2588
-
-
Leng, Y.1
Liang, M.-H.2
Ren, M.3
Marinova, Z.4
Leeds, P.5
Chuang, D.-M.6
-
82
-
-
31944446417
-
The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice
-
DOI 10.1016/j.neulet.2005.10.056, PII S0304394005012437
-
Koh, S. H.; Lee, S. M.; Kim, H. Y.; Lee, K. Y.; Lee, Y. J.; Kim, H. T.; Kim, J.; Kim, M. H.; Hwang, M. S.; Song, C.; Yang, K. W.; Lee, K. W.; Kim, S. H.; Kim, O. H. The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice. Neurosci. Lett., 2006, 395, 103-107 (Pubitemid 43188873)
-
(2006)
Neuroscience Letters
, vol.395
, Issue.2
, pp. 103-107
-
-
Koh, S.-H.1
Lee, S.M.2
Kim, H.Y.3
Lee, K.-Y.4
Lee, Y.J.5
Kim, H.-T.6
Kim, J.7
Kim, M.-H.8
Hwang, M.S.9
Song, C.10
Yang, K.-W.11
Lee, K.W.12
Kim, S.H.13
Kim, O.-H.14
-
83
-
-
0037013685
-
Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors
-
DOI 10.1016/S0960-894X(02)00169-5, PII S0960894X02001695
-
Naerum, L.; Norskov-Lauritsen, L.; Olesen, P. H. Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors. Bioorg. Med. Chem. Lett., 2002, 12, 1525-1528 (Pubitemid 34521927)
-
(2002)
Bioorganic and Medicinal Chemistry Letters
, vol.12
, Issue.11
, pp. 1525-1528
-
-
Narum, L.1
Norskov-Lauritsen, L.2
Olesen, P.H.3
-
84
-
-
34248596671
-
Inhibition of glycogen synthase kinase-3 suppresses the onset of symptoms and disease progression of G93A-SOD1 mouse model of ALS
-
DOI 10.1016/j.expneurol.2007.03.004, PII S0014488607000945
-
Koh, S. H.; Kim, Y.; Kim, H. Y.; Hwang, S.; Lee, C. H.; Kim, S. H. Inhibition of glycogen synthase kinase-3 suppresses the onset of symptoms and disease progression of G93A-SOD1 mouse model of ALS. Exp. Neurol., 2007, 205, 336-346 (Pubitemid 46755762)
-
(2007)
Experimental Neurology
, vol.205
, Issue.2
, pp. 336-346
-
-
Koh, S.-H.1
Kim, Y.2
Kim, H.Y.3
Hwang, S.4
Lee, C.H.5
Kim, S.H.6
-
85
-
-
41149124406
-
Lithium delays progression of amyotrophic lateral sclerosis
-
DOI 10.1073/pnas.0708022105
-
Fornai, F.; Longone, P.; Cafaro, L.; Kastsiuchenka, O.; Ferrucci, M.; Manca, M. L.; Lazzeri, G.; Spalloni, A.; Bellio, N.; Lenzi, P.; Modugno, N.; Siciliano, G.; Isidoro, C.; Murri, L.; Ruggieri, S.; Paparelli, A. Lithium delays progression of amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA, 2008, 105, 2052-2057 (Pubitemid 351439463)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.6
, pp. 2052-2057
-
-
Fornai, F.1
Longone, P.2
Cafaro, L.3
Kastsiuchenka, O.4
Ferrucci, M.5
Manca, M.L.6
Lazzeri, G.7
Spalloni, A.8
Bellio, N.9
Lenzi, P.10
Modugno, N.11
Siciliano, G.12
Isidoro, C.13
Murri, L.14
Ruggieri, S.15
Paparelli, A.16
-
86
-
-
77955873988
-
Lithium carbonate in amyotrophic lateral sclerosis: Lack of efficacy in a dose-finding trial
-
Chiò, A.; Borghero, G.; Calvo, A.; Capasso, M.; Caponnetto, C.; Corbo, M.; Giannini, F.; Logroscino, G.; Mandrioli, J.; Marcello, N.; Mazzini, L.; Moglia, C.; Monsurro, M. R.; Mora, G.; Patti, F.; Perini, M.; Pietrini, V.; Pisano, F.; Pupillo, E.; Sabatelli, M.; Salvi, F.; Silani, V.; Simone, I. L.; Soraru, G.; Tola, M. R.; Volanti, P.; Beghi, E. Lithium carbonate in amyotrophic lateral sclerosis: lack of efficacy in a dose-finding trial. Neurology, 2010, 75, 619-625.
-
(2010)
Neurology
, vol.75
, pp. 619-625
-
-
Chiò, A.1
Borghero, G.2
Calvo, A.3
Capasso, M.4
Caponnetto, C.5
Corbo, M.6
Giannini, F.7
Logroscino, G.8
Mandrioli, J.9
Marcello, N.10
Mazzini, L.11
Moglia, C.12
Monsurro, M.R.13
Mora, G.14
Patti, F.15
Perini, M.16
Pietrini, V.17
Pisano, F.18
Pupillo, E.19
Sabatelli, M.20
Salvi, F.21
Silani, V.22
Simone, I.L.23
Soraru, G.24
Tola, M.R.25
Volanti, P.26
Beghi, E.27
more..
|