Dose response effect of rutin a dietary antioxidant on alcohol-induced prooxidant and antioxidant imbalance - a histopathologic study

Fundamental and Clinical Pharmacology

Volumn 25, Issue 4, 2011, Pages 493-502

  Shenbagam, Madhavan ^a   Nalini, Namasivayam ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Antioxidants; Ethanol; Hepatotoxicity; Lipid peroxidation; Rutin

Indexed keywords

ALCOHOL; ALKADIENE; ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; AMINOTRANSFERASE; ASCORBIC ACID; CATALASE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE SYNTHASE; LIPID HYDROPEROXIDE; RUTOSIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ALKALINE PHOSPHATASE BLOOD LEVEL; AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOSE RESPONSE; ENZYME ACTIVITY; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ALANINE TRANSAMINASE; ALKADIENES; ALKALINE PHOSPHATASE; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASES; BODY WEIGHT; CATALASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GAMMA-GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; LIPID PEROXIDES; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; OXIDATIVE STRESS; RATS; RATS, WISTAR; RUTIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES; VITAMIN E;

EID: 79959939621     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2010.00861.x     Document Type: Article

References (55)

1. Sherlock S. Alcohol and the liver, Sherlock S. (Ed.), Diseases of the liver and biliary system, 6th edn, Blackwell, London, 1995, p. 6.
2. Ponnappa B.C., Rubin E. Modeling alcohol's effects on organs in animal models. Alcohol Res. Health (2000) 24 93-104.
3. Lieber C.S. Alcohol and the liver: metabolism of alcohol and its role in hepatic and extrahepatic diseases. Mt Sinai J. Med. (2000) 67 84-94.
4. Nordmann R., Ribiere C., Rouach H. Implication of free radical mechanisms in ethanol-induced cellular injury. Free Radic. Biol. Med. (1992) 12 219-240.
5. Cederbaum A.I. Introduction-serial review: alcohol, oxidative stress and cell injury. Free Radic. Biol. Med. (2001) 31 1524-1526.
6. Thurman R.G., Handler J.A. New perspectives in catalase-dependent ethanol metabolism. Drug Metab. Rev. (1989) 20 679-688.
7. Plaa G.L., Witschi H. Chemicals, drugs, and lipid peroxidation. Annu. Rev. Pharmacol. Toxicol. (1976) 16 125-141.
8. Wilson R.L. Free radicals and tissue damage, mechanistic evidence from radiation studies, Biochemical mechanisms of liver injury. Academic Press, New York (1988) p. 123.
9. Papadopoulou A., Green R.J., Frazier R.A. Interaction of flavonoids with bovine serum albumin: a fluorescence quenching study. J. Agric. Food. Chem. (2005) 53 158-163.
10. Kurisawa M., Chung J.E., Uyama H., Kobayashi S. Enzymatic synthesis and antioxidant properties of poly (rutin). Biomacromolecules (2003) 4 1394-1399.
11. Manach C., Morand C., Texier O. Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin. J. Nutr. (1995) 125 1911-1922.
12. Deschner E.E., Ruperto J., Wong G., Newmark H.L. Quercetin and rutin as inhibitions of azoxymethanol-induced colonic neoplasia. Carcinogenesis (1991) 12 1193.
13. Chung M.I., Gan K.H., Lin C.N., Ko F.N., Teng C.M. Antiplatelet effects and vasorelaxing action of some constitutes of Formosan plants. J. Nat. Prod. (1993) 56 929.
14. Yang C.S., Landau J.M., Huang M.T., Newmark H.L. Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu. Rev. Nutr. (2001) 21 381-406.
15. Fang S.H., Hou Y.M., Chang W.C. et al. Morin sulfates glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock. Life Sci. (2003) 74 743-756.
16. Reitman S., Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am. J. Clin. Pathol. (1957) 28 56-63.
17. Kind P.R.N., King E.J. Estimation of plasma phosphatase by determination of hydrolysed phenol with amino-antipyrine. J. Clin. Pathol. (1954) 7 322-326.
18. Rosalki S.B., Rau D. Serum-glutamyl transpeptidase activity in alcoholism. Clin. Chim. Acta (1972) 39 41-47.
19. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. (1979) 95 351-358.
20. Jiang Z.Y., Hunt J.V., Wolff S.P. Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxides in low density lipoprotein. Anal. Biochem. (1992) 202 384-389.
21. Rao K.S., Recknagel R.O. Early onset of lipoperoxidation in rat liver after carbon tetrachloride administration. Exp. Mol. Pathol. (1968) 9 271-278.
22. Kakkar B., Das P.N., Viswanathan A. Modified spectrophotometric assay of SOD. Indian J. Biochem. Biophys. (1984) 21 130-132.
23. Sinha A.K. Colorimetric assay of catalase. Anal. Biochem. (1972) 47 389-394.
24. Ellman G.L. Tissue sulphydryl groups. Arch. Biochem. Biophys. (1959) 82 70-77.
25. Flohé L., Günzler W.A. Assays of glutathione peroxidase. Methods Enzymol. (1984) 105 114-121.
26. Habig W.H., Jakoby W.B., llo J. Glutathione S-transferases (rat and human). Methods Enzymol. (1981) 77 218-231.
27. Desai I.D. Vitamin E analysis methods for animal tissues, Feischer S., Packer L. (Eds), Methods enzymol, Academic Press, New York, 1984, pp. 138-145.
28. Omaye S.T., Turnbull J.D., Sauberlich H.E. Selected methods for the determination of ascorbic acid in animal cells, tissues, and fluids. Methods Enzymol. (1979) 62 3-11.
29. Thomson A.D., Baker H., Leevy C.M. Patterns of 35Sthiamin hydrochloride absorption in the malnourished alcoholic patients. J. Lab. Clin. Med. (1970) 76 34-45.
30. Feinman L. Absorption and utilization of nutrients in alcoholism. Alcohol Health Res. World (1989) 13(3) 207-210.
31. Helsby N., Williams J., Kerr D., Gescher A., Chipman J. The isoflavones equol and genistein do not induce xenobiotic metabolizing enzymes in mouse and in human cells. Xenobiotics (1997) 27 587-596.
32. Baldi E., Burra P., Plebani M., Salvagnini M. Serum malondialdehyde and mitochondrial aspartate aminotransferase activity as markers of chronic alcohol intake and alcoholic liver disease. Int. J. Gastroenterol. (1993) 25 429-432.
33. Goldberg D.M., Watts C. Serum enzyme changes as evidence of liver reaction to oral alcohol. Gastroenterology (1965) 49(3) 256-261.
34. Attri S., Rana S.V., Vaiphei K. et al. Isoniazid- and rifampicin-induced oxidative hepatic injury: protection by N-acetylcysteine. Hum. Exp. Toxicol. (2000) 19 517-522.
35. Sadanobu S., Watanabe M., Nakamura C., Tezuka M. In vitro tests of 1, 3-dithia-2 thioxo-cyclopent-4-ene to evaluate the mechanisms of its hepatoprotective action. J. Toxicol. Sci. (1999) 24 375-381.
36. Lim H.K., Kim H.S., Choi H.S. et al. Effects of acetylbergenin against dgalactosamine-induced hepatotoxicity in rats. Pharmacol. Res. (2000) 42 471-474.
37. Korkina L.G., Afanas'ev I.B. Antioxidant and chelating properties of flavonoids. Adv. Pharmacol. (1997) 38 151-163.
38. Thampi H.B.S., Manoj G., Leelamma S., Menon V.P. Dietary fiber and lipid peroxidation: effect of dietary fiber on levels of lipids and lipid peroxides in high fat diet. Indian J. Exp. Biol. (1991) 29 563-567.
39. Ferrali M., Signorini C., Caciotti B. et al. Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity. FEBS Lett. (1997) 416 123-129.
40. Kozlov A.B., Ostrachovitch E.A., Afanas'ev I.B. Mechanism of inhibitory effects of chelating drugs on lipid peroxidation in rat brain homogenates. Biochem. Pharmacol. (1994) 47 795-799.
41. Okado-Matsumoto A., Fridovich I. Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu, Zn-SOD in mitochondria. J. Biol. Chem. (2001) 276 38388-38393.
42. Sheela C.G., Augusti K.T. Antiperoxide effects of S-allyl cysteine sulphoxide isolated from Allium sativum Linn and gugulipid in cholesterol diet fed rats. Indian J. Exp. Biol. (1995) 33 337-341.
43. Jiang P., Burczynski F., Campbell C., Pierce G., Austria J.A., Briggs C.J. Rutin and flavonoid contents in three buckwheat species Fagopyrum esculentum, F. tataricum, and F. homotropicum and their protective effects against lipid peroxidation. Food Res. Int. (2007) 40 356-364.
44. Robak J., Gryglewski R.J. Flavonoids are scavengers of superoxide anions. Biochem. Pharmacol. (1988) 37 837.
45. Polidoro G., De Ilio C., Aruduini A., La Rovere G., Federici G. Superoxide dismutase reduced glutathione and TBA-reactive products in erythrocytes of patients with multiple sclerosis. Int. J. Biochem. (1984) 16 505-509.
46. Yadav P., Sarkar S., Bhatnagar D. Action of Capparis deciduas against alloxan-induced oxidative stress and diabetes in rat tissues. Pharmacol. Res. (1997) 36 221-228.
47. Nakamura Y., Ishimitsu S., Tonogai Y. Effects of quercetin and rutin on serum and hepatic lipid concentrations, fecal steroid excretion and serum antioxidant properties. J. Health Sci. (2000) 46 229-240.
48. Maritim A.C., Sanders R.A., Watkins J.B. III Effects of α-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats. J. Nutr. Biochem. (2003) 14 288-294.
49. Buettner G.R., Schafer F.Q. Free radicals, Oxidants and Antioxidants. Teratology (2000) 62 234.
50. Halliwell B., Gutteridge J.M.C. Free radicals in biology and medicine, 2nd edn, Clarendon Press, London, Oxford, UK, 1989.
51. Sadrzadeh S.M., Nanji A.A., Meydani M. Effect of chronic ethanol feeding on plasma and liver alpha- and gamma-tocopherol levels in normal and vitamin E-deficient rats. Relationship to lipid peroxidation. Biochem. Pharmacol. (1994) 47 2005-2010.
52. Jardao A.A., Chiarello P.G., Arantes M.R., Meiselles M.S., Vannucchi H. Effect of an acute dose of ethanol on lipid peroxidation on rats: action of vitamin E. Food Chem. Toxicol. (2004) 42 1-6.
53. Dupont I., Bodénez P., Berthou F., Simon B., Bardou L.G., Lucas D. Cytochrome P4502E1 activity and oxidative stress in alcoholic patients. Alcohol Alcohol. (2000) 35(1) 98-103.
54. Kidd P.M. Glutathione: systemic protectant against oxidative and free radical damage. Altern. Med. Rev. (1997) 2 155-176.
55. Négre-Salvayre A., Affan A., Hariton C.R. Additional antilipoperoxidant activities of alpha-tocopherol and ascorbic acid on membrane-like systems are potentiated by rutin. Pharmacology (1991) 42 262-272.