When Parkinson's disease patients go to sleep: Specific sleep disturbances related to Parkinson's disease

Journal of Neurology

Volumn 258, Issue SUPPL. 2, 2011, Pages

  Schulte, Eva C ^a   Winkelmann, Juliane ^a,b,c  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Insomnia; Parkinson's disease; Rapid eye movement sleep behavior disorder; Restless legs syndrome; Sleep; Sleep disorders; Sleep disturbances

Indexed keywords

CABERGOLINE; DOPAMINE; DOPAMINE RECEPTOR STIMULATING AGENT; PLACEBO; PRAMIPEXOLE; ROPINIROLE; ROTIGOTINE; SERTRALINE;

CONFERENCE PAPER; DAYTIME SOMNOLENCE; HUMAN; INSOMNIA; PARASOMNIA; PARKINSON DISEASE; PRIORITY JOURNAL; RESTLESS LEGS SYNDROME; SLEEP APNEA SYNDROME; SLEEP DISORDER; SLEEP DISORDERED BREATHING;

BRAIN; HUMANS; PARKINSON DISEASE; REM SLEEP BEHAVIOR DISORDER; SLEEP DISORDERS;

EID: 79959938505     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-011-5933-0     Document Type: Conference Paper

References (71)

1. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisir J, on behalf of the Restless Legs Syndrome Diagnosis and Epidemiology workshop at the National Institutes of Health and the International Restless Legs Syndrome Study Group (2003) Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. Sleep Med 4:101-119
2. Arnulf I, Bonnet AM, Damier P, Bejjani BP, Seilhean D, Derenne J, Agid Y (2000) Hallucinations, REM sleep, and Parkinson's disease: a medical hypothesis. Neurology 55:281-288 (Pubitemid 30604632)
3. Arnulf I, Konofal E, Merino-Andreu M, Houeto JL, Mesnage V, Welter ML, Lacomblez L, Golmard JL, Derenne JP, Agid Y (2002) Parkinson's disease and sleepiness: an integral part of PD. Neurology 58:1019-1024 (Pubitemid 34298539)
4. Askenasy JJ, Yahr MD (1990) Different laws govern motor activity in sleep than in wakefulness. J Neural Transm Gen Sect 79:103-111 (Pubitemid 20002906)
5. Boeve BF, Silber MH, Parisi JE, Dickson DW, Ferman TJ, Benarroch EE, Schmeichel AM, Smith GE, Petersen RC, Ahlskog JE, Matsumoto JY, Kopman DS, Schenck CH, Mahowald MW (2003) Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism. Neurology 61:40-45 (Pubitemid 36818744)
6. Boeve BF, Silber MH, Saper CB, Ferman TJ, Dickson DW, Parisi JE, Benarroch EE, Ahlskog JE, Smith GE, Caselli RC, Tippman-Peikert M, Olson EJ, Lin SC, Young T, Wszolek Z, Schenck CH, Mahowald MW, Castillo PR, Del Tredici K, Braak H (2007) Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain 130:2770-2788 (Pubitemid 350033955)
7. Boeve BF (2010) Predicting the future in idiopathic rapid-eye movement sleep behaviour disorder. Lancet Neurol 9:1040-1042
8. Burn DJ (2002) Beyond the iron mask: towards better recognition and treatment of depression associated with Parkinson's disease. Mov Disord 17:445-454 (Pubitemid 36040955)
9. Chaudhuri KR, Pal S, DiMarco A, Whately-Smith C, Bridgman K, Mathew R, Pezzela FR, Forbes A, Högl B, Trenkwalder C (2002) The Parkinson's disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson's disease. J Neurol Neurosurg Psychiatry 73:629-635 (Pubitemid 35448845)
10. Chaudhuri KR, Schapira AHV (2009) Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment. Lancet Neurol 8:464-474
11. Claassen DO, Josephs KA, Ahlskog JE, Silber MH, Tippmann-Peikert M, Boeve BF (2010) REM sleep behavior disorder preceding other aspects of synucleinopathies by up to half a century. Neurology 75:494-499
12. Cochen de Cock V, Abouda M, Leu S, Qudiette D, Roze E, Vidailhet M, Similowski T, Arnulf I (2010) Is obstructive sleep apnea a problem in Parkinson's disease ? Sleep Med 11:247-252
13. Comella CL, Goetz CG (1994) Akathisia in Parkinson's disease. Mov Disord 9:545-549 (Pubitemid 24275070)
14. Comella CL (2007) Sleep disorders in Parkinson's disease: an overview. Mov Disord 22:S367-S373 (Pubitemid 350134190)
15. De Maindreville AD, Fenelon G, Mahieux (2005) Hallucinations in Parkinson's disease. Mov Disord 20:212-217
16. Dhawan V, Healy DG, Pal S, Chaudhuri KR (2006) Sleep-related problems of Parkinson's disease. Age Ageing 35:220-228
17. Diederich NJ, Vaillant M, Leischen M, Mancuso G, Golinval S, Nati R, Schlesser M (2005) Sleep apnea syndrome in Parkinson's disease. A case-control study in 49 patients. Mov Disord 20:1413-1418 (Pubitemid 43072648)
18. Fenelon G, Mahieux F, Huon R, Ziegler M (2000) Hallucinations in Parkinson's disease: prevalence, phenomenology and risk factors. Brain 123:733-745 (Pubitemid 30162723)
19. Gama RL, Tavora DG, Bomfim RC, Silva CE, de Bruin VM, de Bruin PF (2010) Sleep disturbances and brain MRI morphometry in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy-a comparative study. Parkinsonism Relat Disord 16:275-279
20. Garcia-Borreguero D, Odin P, Serrano C (2005) Restless legs syndrome and PD. Neurology 61:S49-S55
21. Gasser T (2009) Medelian forms of Parkinson's disease. Biochim Biophys Acta 1792:587-596
22. Ghorayeb I, Loundou A, Auquier P, Dauvilliers Y, Bioulac B, Tison F (2007) A nationwide survey of excessive daytime sleepiness in Parkinson's disease in France. Mov Disord 22:1567-1572 (Pubitemid 47477917)
23. Global Parkinson's Disease Survey Steering Committee (2002) Factors impacting on quality of life in Parkinson's disease: results from an international survey. Mov Disord 17:60-67
24. Goulart FO, Godke BA, Borges V, Azevedo-Silva SMC, Mendes MF, Cendoroglo MS, Ferraz HB (2009) Fatigue in a cohort of geriatric patients with and without Parkinson's disease. Braz J Med Biol Res 42:771-775
25. Happe S, Pirker W, Kölsch G, Sauter C, Zeitlhofer J (2003) Periodic leg movements in patients with Parkinson's disease are associated with reduced striatal dopamine transporter binding. J Neurol 250:83-86 (Pubitemid 36206689)
26. Hampp G, Ripperger JA, Houben T, Schmutz I, Blex C, Perreau-Lenz S, Brunk I, Spanagel R, Ahnert-Hilger G, Meijer JH, Albrecht U (2008) Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Curr Biol 18:678-683
27. Healy DG, Falchi M, O'Sullivan SS, Bonifati V, Durre A, Bressman S, Brice A, Aaslyi J, Zabetian CP, Goldwurm S, Ferreira JJ, Tolos D, Kay DM, Klein C, Williams DR, Marras C, Lang AE, Wszolek ZK, Bercianos J, Schapira AHV, Lynch R, Bhatia KP, Gasser T, Lees SJ, Wood NW, on behalf of the International LRRK2 Consortium (2008) Phenotype, genotype, and worldwide genetic pentrance of LRRK2-associated Parkinson's disease: a case-control study. Lancet Neurol 7:583-590
28. Högl B, Rothdach A, Wetter TC, Trenkwalder C (2003) The effect of cabergoline on sleep, periodic leg movements in sleep, and early morning motor function in patients with Parkinson's disease. Neuropsychopharmacology 28:1866-1870 (Pubitemid 41070852)
29. Högl B, Seppi K, Brandauer E, Glatzl S, Frauscher B, Niedermüller U, Wenning G, Poewe W (2003) Increased daytime sleepiness in Parkinson's disease: a questionnaire survey. Mov Disord 18:319-323 (Pubitemid 36410829)
30. Högl B, Arnulf I, Comella C, Ferreira J, Iranzo A, Tilley B, Trenkwalder C, Poewe W, Rascol O, Sampaio C, Stebbins GT, Schrag A, Goetz CG (2010) Scales to assess sleep impairment in Parkinson's disease: critique and recommendations. Mov Disord (in press). (doi:10.1002/mds.23190)
31. 2 dopamine receptors. J Neurosci 30:14046-14058
32. Iranzo A, Omena F, Stockner H, Valldeoriola F, Vilaseca I, Salamero M, Molinuevo JL, Serradell M, Duch J, Pavia J, Gallego J, Seppi K, Högl B, Tolosa E, Poewe W, Sanatamaria J, for the Sleep Innsbruck Barcelona (SINBAR) group (2010) Decreased striatal dopamine transporter uptake and substantia nigra hyperechogenicity as risk markers of synucleinopathy in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study. Lancet Neurol 9:1070-1077
33. Lee JE, Shin HW, Kim KS, Sohn YH (2009) Factors contributing to the development of restless legs syndrome in patients with Parkinson's disease. Mov Disord 24:579-582
34. Löhle M, Storch A, Reichmann H (2009) Beyond tremor and rigidity: non-motor features of Parkinson's disease. J Neural Transm 116:1483-1492
35. Lu BS, Zee PC (2010) Neurobiology of Sleep. Clin Chest Med 31:309-318
36. Mahowald MW, Schenck CH (2005) Insights from studying human sleep disorders. Nature 437:1279-1285 (Pubitemid 41568668)
37. Manni R, Pacchetti C, Terzaghi M, Sartori I, Mancini F, Nappi G (2002) Hallucinations and sleep-wake cycle in PD: a 24-hour continuous polysomnographic study. Neurology 59:1979-1981 (Pubitemid 36082814)
38. Maria B, Sophia S, Michalis M, Charalampos L, Andreas P, John ME, Nikolaos SM (2003) Sleep breathing disorders in patients with idiopathic Parkinson's disease. Respir Med 97:1151-1157 (Pubitemid 37185119)
39. Martinez-Martin P, Schapira AHV, Stocchi F, Sethi K, Odin P, MacPhee G, Brown RG, Naidu Y, Clayton L, Abe K, Tsuboi Y, MacMahon D, Barone P, Rabey M, Bonuccelli U, Forbes A, Breen K, Tluk S, Olanow CW, Thomas S, Rye D, Hand A, Williams AJ, Ondo W, Chaudhuri KR (2007) Prevalence of nonmotor symptoms in Parkinson's disease in an international setting: study using nonmotor symptoms questionnaire in 545 patients. Mov Disord 22:1623-1629 (Pubitemid 47477925)
40. Möller JC, Unger M, Stiasny-Kolster K, Oertel WH (2009) Restless legs syndrome and Parkinson's disease-Related disorders or different entities? J Neurol Sci 289:135-137
41. Ng KY, Chase TN, Colburn RW, Kopin IJ (1971) Dopamine stimulation induced release from central neurons. Science 1172:487-489
42. Noradina AT, Karim NA, Hmidon BB, Norlinah I, Raymond AA (2010) Sleep-disordered breathing in patients with Parkinson's disease. Singapore Med J 51:60-64
43. Ondo WG, Dat Vuong K, Khan H, Atassi F, Kwak C, Jankovic J (2001) Daytime sleepiness and other sleep disorders in Parkinson's disease. Neurology 57:1392-1396 (Pubitemid 32995718)
44. Onofrj M, Thomas A, D'Andreamatteo G, Iacono D, Luciano AL, Di Rollo A, Di Mascio R, Ballone E, Di Iorio A (2002) Incidence of RBD and hallucination in patients affected by Parkinson's disease: 8-year follow-up. Neurol Sci 23:S91-S94 (Pubitemid 35355792)
45. O'Sullivan SS, Williams DR, Gallagher DA, Massey LA, Silveira-Moriyama L, Lees AJ (2008) Non motor symptoms as presenting complaints in Parkinson's disease: a clinicopathological study. Mov Disord 23:101-106 (Pubitemid 351281225)
46. Pacchetti C, Manni R, Zangaglia R, Mancini F, Marchioni E, Tassorelli C, Terzaghi M, Ossola M, Martignoni E, Moglia A, Nappi G (2005) Mov Disord 20:1439-1448
47. Pahwa R, Stacy MA, Factor SA, Lyons KE, Stocchi F, Hersh BP, Elmer LW, Truong DD, Earl NL, on behalf of the EASE-PD Adjunct Study Investigators (2007) Ropinirole 24-hour prolonged release: randomized, controlled study in advanced Parkinson disease. Neurology 68:1108-1115 (Pubitemid 46559844)
48. Paus S, Brecht HM, Koster J, Seeger G, Klockgether T, Wullner U (2003) Sleep attacks, daytime sleepiness, and dopamine agonists in Parkinson's disease. Mov Disord 18:659-667 (Pubitemid 36790281)
49. Peralta CM, Frauscher B, Seppi K, Wolf E, Wenning GK, Högl B, Poewe W (2009) Restless legs syndrome in Parkinson's disease. Mov Disord 24:2076-2080
50. Pichler I, Marroni F, Pattaro C, Lohmann K, De Grandi A, Klein C, Hicks AA, Pramstaller PP (2009) Parkin gene modifies the effect of RLS4 on the age at onset of restless legs syndrome. Am J Med Genet 153B:350-355
51. Poewe W, Rascol O, Quinn N, Tolosa E, Oertel WH, Martignoni E, Rupp M, Boroojerdi B, on behalf of the SP 515 Investigators (2007) Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: a double-blind, double-dummy randomized controlled trial. Lancet Neurol 6:513-520 (Pubitemid 46734759)
52. Poryazova R, Benninger D, Waldvogel D, Bassetti CL (2010) Excessive daytime sleepiness in Parkinson's disease: characteristics and determinants. Eur Neurol 63:129-135
53. Postuma RB, Gagnon JF, Vendette M, Fantini ML, Massicotte-Marquez J, Montplaisir J (2009) Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behaviour disorder. Neurology 72:1296-1300
54. Razamy A, Lang AE, Shapiro CM (2004) Predictors of impaired daytime sleep and wakefulness in patients with Parkinson disease treated with older (ergot) vs newer (nonergot) dopamine agonists. Arch Neurol 61:97-102 (Pubitemid 38067420)
55. Reichmann H, Brecht MH, Koster J, Kraus PH, Lemke MR (2003) Pramipexole in routine clinical practice: a prospective observational trial in Parkinson's disease. CNS Drugs 17:965-973 (Pubitemid 37410070)
56. Remy P, Doder M, Lees A, Turjanski N, Brooks D (2005) Depression in Parkinson's disease. Loss of dopamine and noradrenaline innervations in the limbic system. Brain 12:1314-1322 (Pubitemid 40826185)
57. Rye DB, Jankovic J (2002) Emerging views of dopamine in modulating sleep/wake state from an unlikely source: PD. Neurology 58:341-346 (Pubitemid 34150904)
58. Satake W, Nakabayashi Y, Mizuta I, Hirota Y, Ito C, Kubo M, Kawaguchi T, Tsunoda T, Watanabe M, Takeda A, Tomiyama H, Nakashima K, Hasegawa K, Obata F, Yoshikawa T, Kawakami H, Sakoda S, Yamamoto M, Hattori N, Murata M, Nakamura Y, Toda T (2009) Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat Genet 41:1303-1307
59. Schormair B, Kemlink D, Roeske D, Eckstein G, Xiong L, Lichtner P, Ripke S, Trenkwalder C, Zimprich A, Stiasny-Kolster K, Oertel W, Bachmann CG, Paulus W, Högl B, Frauscher B, Gschliesser V, Poewe W, Peglau I, Vodicka P, Vavrova J, Sonka K, Nevsimalova S, Montplaisir J, Turecki G, Rouleau G, Gieger C, Illig T, Wichmann HE, Holsboer F, Müller-Myhsok B, Meitinger T, Winkelmann J (2008) PTPRD (protein tyrosin phosphatase receptor type delta) is associated with restless legs syndrome. Nat Genet 40:946-948
60. Shpirer I, Miniovitz A, Klein C, Goldstein R, Prokohorov T, Theitler J, Rabey JM (2006) Excessive daytime sleepiness in patients with Parkinson's disease: a polysomnography study. Mov Disord 21:1432-1438 (Pubitemid 44613296)
61. Simon-Sanchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, Berg D, Paison-Ruiz C, Lichtner P, Scholz SW, Hernandez DG, Krüger R, Federoff M, Klein C, Goate A, Perlmutter J, Bonin M, Nalls MA, Illig T, Gieger C, Houlden H, Steffens M, Okun MS, Racette BA, Cookson MR, Foote KD, Fernandez HH, Traynor BJ, Schreiber S, Arepalli S, Zonozi R, Gwinn K, van der Brug M, Lopez G, Chanock SJ, Schatzkin A, Park Y, Hollenbeck A, Gao J, Huang X, Wood NW, Lorenz D, Deuschl G, Chen H, Riess O, Hardy JA, Singleton AB, Gasser T (2009) Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet 41:1308-1312
62. Stefansson H, Rye DB, Hicks A, Petursson H, Ingason A, Thorgeirsson TE, Palsson S, Sigmundsson T, Sigurdsson AP, Eiriksdottir I, Soebech E, Bliwise D, Beck JM, Rosen A, Waddy S, Trotti LM, Iranzo A, Thambisetty M, Hardarson GA, Kristjansson K, Gudmundsson LJ, Thorseinsdottir U, Kong A, Gulcher JR, Gudbjartsson D, Stefansson K (2007) N Engl J Med 357:639-647
63. Stevens S, Cormella CL, Stepanski EJ (2004) Daytime sleepiness and alertness in patients with Parkinson disease. Sleep 27:967-972 (Pubitemid 39095730)
64. Tan EK, Lum SY, Fook-Chong SM, Teoh ML, Yih Y, Tan L, Tan A, Wong MC (2002) Evaluation of somnolence in Parkinson's disease: comparison with age-and sex-matched controls. Neurology 58:465-468 (Pubitemid 34150926)
65. Tandberg E, Larsen JP, Karlsen K (1998) A community-based study of sleep disorders in patients with Parkinson's disease. Mov Disord 13:895-899 (Pubitemid 28517665)
66. Trenkwalder C, Kohnen R, Högl B, Metta V, Sixel-Döring F, Frauscher B, Hülsmann J, Martinez-Martin P, Chaudhuri KR (2010) Parkinson's disease sleep scale-validation of the revised version PDSS-2. Mov Disord (in press)
67. Vilarino-Güell C, Soto AI, Young JE, Lin SC, Uitti RJ, Wszolek ZK, Farrer MJ (2008) Susceptibility genes for restless legs syndrome are not aassociated with Parkinson disease. Neurology 71:222-223
68. Wetter TC, Collado-Seidel V, Pollmöcher T, Yassouridis A, Trenkwalder C (2000) Sleep and periodic leg movement patterns in drug-free patients with Parkinson's disease and multiple system atrophy. Sleep 23:361-367 (Pubitemid 30263169)
69. Wetter TC, Brunner H, Högl B, Yassouridis A, Trenkwalder C, Friess E (2001) Increased alpha activity in REM sleep in de novo patients with Parkinson's disease. Mov Disord 16:928-933 (Pubitemid 36041197)
70. Winkelmann J, Schormair B, Lichtner P, Ripke S, Xiong L, Jalizadeh S, Fulda S, Pütz B, Eckstein G, Hauk S, Trenkwalder C, Zimprich A, Stiasny-Kolster K, Oertel W, Bachmann CG, Paulus W, Peglau I, Eisensehr I, Montplaisir J, Turecki G, Rouleau G, Gieger C, Illig T, Wichmann HE, Holsboer F, Müller-Myhsok B, Meitinger T (2007) Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. Nat Genet 39:1000-1006 (Pubitemid 47185185)
71. Winkelmann J, Polo O, Provini F, Nevsimalova S, Kemlink D, Sonka K, Högl B, Poewe W, Stiasny-Kolster K, Oertel W, de Weerd A, Ferini-Strambi L, Zucconi M, Pramstaller PP, Arnulf I, Trenkwalder C, Klein C, Hadjigeorgiou GM, Happe S, Rye D, Montagna P (2007) Genetics of restless legs syndrome (RLS): state-of-the-art and future directions. Mov Disord 22:S449-S458