Neurobiology of sleep

Clinics in Chest Medicine

Volumn 31, Issue 2, 2010, Pages 309-318

  Lu, Brandon S ^a   Zee, Phyllis C ^b  

^a CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Sleep disorders; Sleep neurobiology; Sleep regulation; Sleep wake transition

Indexed keywords

ADENOSINE A2 RECEPTOR; DIPHENHYDRAMINE; DOPAMINE; DOPAMINE 1 RECEPTOR; HISTAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; NORADRENALIN; OREXIN; OREXIN 2 RECEPTOR; PROTEIN FOS; SEROTONIN;

AROUSAL; CHOLINERGIC SYSTEM; CIRCADIAN RHYTHM; DRUG MECHANISM; EPIDEMIC ENCEPHALITIS; HUMAN; INSOMNIA; MONOAMINERGIC SYSTEM; NARCOLEPSY; NEUROBIOLOGY; NONHUMAN; NONREM SLEEP; PREOPTIC NUCLEUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REM SLEEP; REVIEW; SLEEP; SLEEP WAKING CYCLE; WAKEFULNESS;

CIRCADIAN RHYTHM; DOPAMINE; HISTAMINE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NEUROPEPTIDES; NOREPINEPHRINE; SLEEP; SLEEP, REM; WAKEFULNESS;

EID: 77952938154     PISSN: 02725231     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccm.2010.02.004     Document Type: Review

References (98)

1. Durmer J.S., Dinges D.F. Neurocognitive consequences of sleep deprivation. Semin Neurol 2005, 25:117-129.
2. Oliver S.J., Costa R.J., Laing S.J., et al. One night of sleep deprivation decreases treadmill endurance performance. Eur J Appl Physiol 2009, 107:155-161.
3. Gottlieb D.J., Redline S., Nieto F.J., et al. Association of usual sleep duration with hypertension: the Sleep Heart Health Study. Sleep 2006, 29:1009-1014.
4. Ayas N.T., White D.P., Al-Delaimy W.K., et al. A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care 2003, 26:380-384.
5. Patel S.R., Ayas N.T., Malhotra M.R., et al. A prospective study of sleep duration and mortality risk in women. Sleep 2004, 27:440-444.
6. Porkka-Heiskanen T., Strecker R.E., Thakkar M., et al. Adenosine: a mediator of the sleep-inducing effects of prolonged wakefulness. Science 1997, 276:1265-1268.
7. Lu J., Greco M.A., Shiromani P., et al. Effect of lesions of the ventrolateral preoptic nucleus on NREM and REM sleep. J Neurosci 2000, 20:3830-3842.
8. Berger H. Ueber das Elektroenkephalogrammdes Menschen. J Psychol Neurol 1930, 40:169-179. [in German].
9. von Economo C. Sleep as a problem of localization. J Nerv Ment Dis 1930, 71:249-259.
10. Moruzzi G., Magoun H.W. Brain stem reticular formation and activation of the EEG. Electroencephalogr Clin Neurophysiol 1949, 1:455-473.
11. Armstrong D.M., Saper C.B., Levey A.I., et al. Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase. J Comp Neurol 1983, 216:53-68.
12. Woolf N.J. Cholinergic systems in mammalian brain and spinal cord. Prog Neurobiol 1991, 37:475-524.
13. Jasper H.H., Tessier J. Acetylcholine liberation from cerebral cortex during paradoxical (REM) sleep. Science 1971, 172:601-602.
14. Steriade M., Datta S., Pare D., et al. Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems. J Neurosci 1990, 10:2541-2559.
15. Rye D.B., Wainer B.H., Mesulam M.M., et al. Cortical projections arising from the basal forebrain: a study of cholinergic and noncholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase. Neuroscience 1984, 13:627-643.
16. Jones B.E. Activity, modulation and role of basal forebrain cholinergic neurons innervating the cerebral cortex. Prog Brain Res 2004, 145:157-169.
17. Buzsaki G., Bickford R.G., Ponomareff G., et al. Nucleus basalis and thalamic control of neocortical activity in the freely moving rat. J Neurosci 1988, 8:4007-4026.
18. Mesulam M.M., Mufson E.J., Wainer B.H., et al. Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6). Neuroscience 1983, 10:1185-1201.
19. Saper C.B., Scammell T.E., Lu J. Hypothalamic regulation of sleep and circadian rhythms. Nature 2005, 437:1257-1263.
20. Hobson J.A., McCarley R.W., Wyzinski P.W. Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups. Science 1975, 189:55-58.
21. Aston-Jones G., Bloom F.E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J Neurosci 1981, 1:876-886.
22. Berridge C.W., Foote S.L. Effects of locus coeruleus activation on electroencephalographic activity in neocortex and hippocampus. J Neurosci 1991, 11:3135-3145.
23. Berridge C.W., Page M.E., Valentino R.J., et al. Effects of locus coeruleus inactivation on electroencephalographic activity in neocortex and hippocampus. Neuroscience 1993, 55:381-393.
24. Berridge C.W. Noradrenergic modulation of arousal. Brain Res Rev 2008, 58:1-17.
25. Valentino R.J., Page M.E., Curtis A.L. Activation of noradrenergic locus coeruleus neurons by hemodynamic stress is due to local release of corticotropin-releasing factor. Brain Res 1991, 555:25-34.
26. Trulson M.E., Jacobs B.L. Raphe unit activity in freely moving cats: correlation with level of behavioral arousal. Brain Res 1979, 163:135-150.
27. Koella W.P. Serotonin and sleep. Exp Med Surg 1969, 27:157-168.
28. Bjorvatn B., Fagerland S., Eid T., et al. Sleep/waking effects of a selective 5-HT1A receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats. Brain Res 1997, 770:81-88.
29. Bjorvatn B., Ursin R. Effects of zimeldine, a selective 5-HT reuptake inhibitor, combined with ritanserin, a selective 5-HT2 antagonist, on waking and sleep stages in rats. Behav Brain Res 1990, 40:239-246.
30. Bjorvatn B., Ursin R. Effects of the selective 5-HT1B agonist, CGS 12066B, on sleep/waking stages and EEG power spectrum in rats. J Sleep Res 1994, 3:97-105.
31. Ursin R. The effects of 5-hydroxytryptophan and L-tryptophan on wakefulness and sleep patterns in the cat. Brain Res 1976, 106:105-115.
32. Ko E.M., Estabrooke I.V., McCarthy M., et al. Wake-related activity of tuberomammillary neurons in rats. Brain Res 2003, 992:220-226.
33. Siegel J.M., Boehmer L.N. Narcolepsy and the hypocretin system-where motion meets emotion. Nat Clin Pract Neurol 2006, 2:548-556.
34. Tasaka K., Chung Y.H., Sawada K., et al. Excitatory effect of histamine on the arousal system and its inhibition by H1 blockers. Brain Res Bull 1989, 22:271-275.
35. Sander K., Kottke T., Stark H. Histamine H3 receptor antagonists go to clinics. Biol Pharm Bull 2008, 31:2163-2181.
36. Weiner D.M., Levey A.I., Sunahara R.K., et al. D1 and D2 dopamine receptor mRNA in rat brain. Proc Natl Acad Sci U S A 1991, 88:1859-1863.
37. Monti J.M., Monti D. The involvement of dopamine in the modulation of sleep and waking. Sleep Med Rev 2007, 11:113-133.
38. Le Moal M., Simon H. Mesocorticolimbic dopaminergic network: functional and regulatory roles. Physiol Rev 1991, 71:155-234.
39. Schultz W. Predictive reward signal of dopamine neurons. J Neurophysiol 1998, 80:1-27.
40. Fadel J., Deutch A.Y. Anatomical substrates of orexin-dopamine interactions: lateral hypothalamic projections to the ventral tegmental area. Neuroscience 2002, 111:379-387.
41. Kitai S.T., Shepard P.D., Callaway J.C., et al. Afferent modulation of dopamine neuron firing patterns. Curr Opin Neurobiol 1999, 9:690-697.
42. Lokwan S.J., Overton P.G., Berry M.S., et al. Stimulation of the pedunculopontine tegmental nucleus in the rat produces burst firing in A9 dopaminergic neurons. Neuroscience 1999, 92:245-254.
43. White F.J. Synaptic regulation of mesocorticolimbic dopamine neurons. Annu Rev Neurosci 1996, 19:405-436.
44. Wisor J.P., Nishino S., Sora I., et al. Dopaminergic role in stimulant-induced wakefulness. J Neurosci 2001, 21:1787-1794.
45. Rye D.B. Parkinson's disease and RLS: the dopaminergic bridge. Sleep Med 2004, 5:317-328.
46. Monti J.M., Jantos H., Fernandez M. Effects of the selective dopamine D-2 receptor agonist, quinpirole on sleep and wakefulness in the rat. Eur J Pharmacol 1989, 169:61-66.
47. Sakurai T., Amemiya A., Ishii M., et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998, 92:573-585.
48. de Lecea L., Kilduff T.S., Peyron C., et al. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A 1998, 95:322-327.
49. Bayer L., Eggermann E., Saint-Mleux B., et al. Selective action of orexin (hypocretin) on nonspecific thalamocortical projection neurons. J Neurosci 2002, 22:7835-7839.
50. Burlet S., Tyler C.J., Leonard C.S. Direct and indirect excitation of laterodorsal tegmental neurons by Hypocretin/Orexin peptides: implications for wakefulness and narcolepsy. J Neurosci 2002, 22:2862-2872.
51. Eggermann E., Serafin M., Bayer L., et al. Orexins/hypocretins excite basal forebrain cholinergic neurones. Neuroscience 2001, 108:177-181.
52. Eriksson K.S., Sergeeva O., Brown R.E., et al. Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus. J Neurosci 2001, 21:9273-9279.
53. Horvath T.L., Peyron C., Diano S., et al. Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system. J Comp Neurol 1999, 415:145-159.
54. Liu R.J., van den Pol A.N., Aghajanian G.K. Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions. J Neurosci 2002, 22:9453-9464.
55. Shirasaka T., Nakazato M., Matsukura S., et al. Sympathetic and cardiovascular actions of orexins in conscious rats. Am J Phys 1999, 277:R1780-R1785.
56. Yamuy J., Fung S.J., Xi M., et al. Hypocretinergic control of spinal cord motoneurons. J Neurosci 2004, 24:5336-5345.
57. Lee M.G., Hassani O.K., Jones B.E. Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle. J Neurosci 2005, 25:6716-6720.
58. Chemelli R.M., Willie J.T., Sinton C.M., et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 1999, 98:437-451.
59. Lin L., Faraco J., Li R., et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 1999, 98:365-376.
60. Mignot E., Lammers G.J., Ripley B., et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 2002, 59:1553-1562.
61. Thannickal T.C., Moore R.Y., Nienhuis R., et al. Reduced number of hypocretin neurons in human narcolepsy. Neuron 2000, 27:469-474.
62. Jones B.E. Arousal systems. Front Biosci 2003, 8:s438-s451.
63. Sherin J.E., Shiromani P.J., McCarley R.W., et al. Activation of ventrolateral preoptic neurons during sleep. Science 1996, 271:216-219.
64. Lu J., Bjorkum A.A., Xu M., et al. Selective activation of the extended ventrolateral preoptic nucleus during rapid eye movement sleep. J Neurosci 2002, 22:4568-4576.
65. Sakurai T., Nagata R., Yamanaka A., et al. Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. Neuron 2005, 46:297-308.
66. Chou T.C., Bjorkum A.A., Gaus S.E., et al. Afferents to the ventrolateral preoptic nucleus. J Neurosci 2002, 22:977-990.
67. Marcus J.N., Aschkenasi C.J., Lee C.E., et al. Differential expression of orexin receptors 1 and 2 in the rat brain. J Comp Neurol 2001, 435:6-25.
68. Suntsova N., Szymusiak R., Alam M.N., et al. Sleep-waking discharge patterns of median preoptic nucleus neurons in rats. J Physiol 2002, 543:665-677.
69. Gvilia I., Xu F., McGinty D., et al. Homeostatic regulation of sleep: a role for preoptic area neurons. J Neurosci 2006, 26:9426-9433.
70. Saper C.B., Chou T.C., Scammell T.E. The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci 2001, 24:726-731.
71. Espana R.A., Scammell T.E. Sleep neurobiology for the clinician. Sleep 2004, 27:811-820.
72. Kubin L. Carbachol models of REM sleep: recent developments and new directions. Arch Ital Biol 2001, 139:147-168.
73. Qureshi A., Lee-Chiong T. Medications and their effects on sleep. Med Clin North Am 2004, 88:751-766. x.
74. Jones B.E., Harper S.T., Halaris A.E. Effects of locus coeruleus lesions upon cerebral monoamine content, sleep-wakefulness states and the response to amphetamine in the cat. Brain Res 1977, 124:473-496.
75. Shouse M.N., Siegel J.M. Pontine regulation of REM sleep components in cats: integrity of the pedunculopontine tegmentum (PPT) is important for phasic events but unnecessary for atonia during REM sleep. Brain Res 1992, 571:50-63.
76. Lu J., Sherman D., Devor M., et al. A putative flip-flop switch for control of REM sleep. Nature 2006, 441:589-594.
77. Sastre J.P., Buda C., Kitahama K., et al. Importance of the ventrolateral region of the periaqueductal gray and adjacent tegmentum in the control of paradoxical sleep as studied by muscimol microinjections in the cat. Neuroscience 1996, 74:415-426.
78. Boissard R., Gervasoni D., Schmidt M.H., et al. The rat ponto-medullary network responsible for paradoxical sleep onset and maintenance: a combined microinjection and functional neuroanatomical study. Eur J Neurosci 2002, 16:1959-1973.
79. Sakai K., Crochet S., Onoe H. Pontine structures and mechanisms involved in the generation of paradoxical (REM) sleep. Arch Ital Biol 2001, 139:93-107.
80. Sanford L.D., Morrison A.R., Mann G.L., et al. Sleep patterning and behaviour in cats with pontine lesions creating REM without atonia. J Sleep Res 1994, 3:233-240.
81. Chase M.H., Soja P.J., Morales F.R. Evidence that glycine mediates the postsynaptic potentials that inhibit lumbar motoneurons during the atonia of active sleep. J Neurosci 1989, 9:743-751.
82. Fuller P.M., Saper C.B., Lu J. The pontine REM switch: past and present. J Physiol 2007, 584:735-741.
83. Brischoux F., Mainville L., Jones B.E. Muscarinic-2 and orexin-2 receptors on GABAergic and other neurons in the rat mesopontine tegmentum and their potential role in sleep-wake state control. J Comp Neurol 2008, 510:607-630.
84. Lu J. Neuroanatomical and genetic dissection of brain circuitry regulating REM sleep behavior disorder (RBD) and cataplexy. Sleep Med 2007, 8:S8.
85. Borbély A.A. A two process model of sleep regulation. Hum Neurobiol 1982, 1:195-204.
86. Benington J.H., Heller H.C. Restoration of brain energy metabolism as the function of sleep. Prog Neurobiol 1995, 45:347-360.
87. Ticho S.R., Radulovacki M. Role of adenosine in sleep and temperature regulation in the preoptic area of rats. Pharmacol Biochem Behav 1991, 40:33-40.
88. Feldberg W., Sherwood S.L. Infections of drugs into the lateral ventricle of the cat. J Physiol 1954, 123:148-167.
89. Haulica I., Ababei L., Branisteanu D., et al. Preliminary data on the possible hypnogenic role of adenosine. Rev Roum Physiol 1973, 10:275-279.
90. Strecker R.E., Morairty S., Thakkar M.M., et al. Adenosinergic modulation of basal forebrain and preoptic/anterior hypothalamic neuronal activity in the control of behavioral state. Behav Brain Res 2000, 115:183-204.
91. Scammell T.E., Gerashchenko D.Y., Mochizuki T., et al. An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons. Neuroscience 2001, 107:653-663.
92. Moore R.Y. A clock for the ages. Science 1999, 284:2102-2103.
93. Dijk D.J., Czeisler C.A. Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans. J Neurosci 1995, 15:3526-3538.
94. Edgar D.M., Dement W.C., Fuller C.A. Effect of SCN lesions on sleep in squirrel monkeys: evidence for opponent processes in sleep-wake regulation. J Neurosci 1993, 13:1065-1079.
95. Watts A.G., Swanson L.W., Sanchez-Watts G. Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat. J Comp Neurol 1987, 258:204-229.
96. Chou T.C., Scammell T.E., Gooley J.J., et al. Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci 2003, 23:10691-10702.
97. Lu J., Zhang Y.H., Chou T.C., et al. Contrasting effects of ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep-wake cycle and temperature regulation. J Neurosci 2001, 21:4864-4874.
98. Deurveilher S., Semba K. Indirect projections from the suprachiasmatic nucleus to major arousal-promoting cell groups in rat: implications for the circadian control of behavioural state. Neuroscience 2005, 130:165-183.