Mass spectrometric imaging (MSI) of metals using advanced BrainMet techniques for biomedical research

International Journal of Mass Spectrometry

Volumn 307, Issue 1-3, 2011, Pages 3-15

  Becker, Johanna Sabine ^a   Matusch, Andreas ^a   Becker, Julia Susanne ^b   Wu, Bei ^a   Palm, Christoph ^c   Becker, Albert Johann ^d   Salber, Dagmar ^a  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b Aeropharm GmbH   (Germany)

^c UNIVERSITY OF APPLIED SCIENCES REGENSBURG   (Germany)

^d UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Bioimaging; Brain tissue; Laser ablation inductively coupled plasma mass spectrometry; Laser microdissection inductively coupled plasma mass spectrometry; Metallomics; Metals; Nano LA ICP MS; Tumour

Indexed keywords

EID: 79959937495     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2011.01.015     Document Type: Article

References (70)

1. J.S. Becker, and D. Salber BrainMet - bioimaging of metals in brain and metallomics: new mass spectrometric tools in brain research Trends Anal. Chem. 29 2010 966 978
2. W. Shi, and M.R. Chance Metallomics and metalloproteomics Cell. Mol. Life Sci. (CMLS) 65 2008 3040 3048
3. A. Sigel, H. Sigel, and R.K.O. Sigel Neurodegenerative Diseases and Metal Ions 2006 John Wiley & Sons, Ltd. Chichester
4. S.S. Rubakhin, and J.V. Sweedler Mass spectrometric imaging: principles and protocols Methods in Molecular Biology 2010 Springer Heidelberg
5. R. Lobinski, J.S. Becker, H. Haraguchi, and B. Sarkar Metals in biological systems and -omics: guidelines for terminology and critical evaluation of analyical chemistry approaches (IUPAC technical report) Pure Appl. Chem. 82 2010 493 504
6. L.M. Wang, Q. Wu, J.S. Becker, M.F. Oliveira, F.A. Bozza, A.L. Schwager, M. Lee, J.M. Hoffman, and K.A. Morton Alterations in copper uptake, content and distribution in the brains of aging mice Metallomics 2 2010 348 353
7. J.S Becker, M. Zoriy, A. Matusch, B. Wu, D. Salber, C. Palm, and J.S. Becker Bioimaging of metals by LA-ICP-MS Mass Spectrom. Rev. 29 2010 156 175
8. J.S. Becker, A. Matusch, C. Palm, D. Salber, K. Morton, and J.S. Becker Bioimaging of metals in brain tissue by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and metallomics Metallomics 2 2010 104 111
9. A. Matusch, C. Depboylu, C. Palm, B. Wu, G.U. Höglinger, M.K.-H. Schäfer, and J.S. Becker Cerebral bio-imaging of Cu, Fe, Zn and Mn in the MPTP mouse model of Parkinson's disease using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) J. Am. Soc. Mass Spectrom. 21 2010 161 171
10. J.S. Becker Bioimaging of metals in brain tissue from micrometre to nanometre scale by laser ablation inductively coupled plasma mass spectrometry: state of the art and perspectives Int. J. Mass Spectrom. 289 2010 65 75
11. A. Zayed, T. Shoeib, S.E. Taylor, G.D. Jones, A.L. Thomas, J.P. Wood, H.J. Reid, B.L. Sharp, Determination of Pt-DNA adducts and the sub-cellular distribution of Pt in human cancer cell lines and the leukocytes of cancer patients, following mono- or combination treatments, by inductively-coupled plasma mass spectrometry, Int. J. Mass Spectrom., this issue.
12. G. Zhang, W. Hu, Z. Du, S. Lv, Q. Iuo, X. Li, K. Wu, Y. Han, F. Wang, A comparative study on interactions of cisplatin and ruthenium arene anticancer complexes with metallothionein using MALDI-TOF-MS, Int. J. Mass Spectrom., this issue.
13. K. Nakazato, T. Nagamine, K. Suzuki, T. Kusakabe, H.D. Moon, M. Oikawa, T. Sakai, and K. Arakawa Suncellular changes of essential metal shown by microPIXE in oral cadmium-exposed mice BioMetals 21 2008 83 91 (Pubitemid 351170144)
14. H.R. Pohl, H.G. Abadin, and J.F. Risher Neurotoxicity of cadmium, lead and mercury H.S.A. Sigel, R.K.O. Sigel, Metal Ions in Life Sciences 2006 Wiley and Sons Chichester 395 425
15. D.J. Bellis, D. Li, Z. Chen, W.M. Gibson, and P.J. Parsons Measurement of the microdistribution of strontium and lead in bone via benchtop monochromatic microbeam X-ray fluorescence with a low power source J. Anal. At. Spectrom. 24 2009 622 626
16. W. Ribi, T.J. Senden, A. Sakellariou, A. Limayec, and S. Zhang Imaging honey bee brain anatomy with micro-X-ray-computed tomography J. Neurosci. Methods 171 2008 93 97
17. L.M. Miller, Q. Wang, T.P. Telivala, R.J. Smith, A. Lanzirotti, and J. Miklossy Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease J. Struct. Biol. 155 2006 30 37 (Pubitemid 43867313)
18. T. Punshon, B.P. Jackson, A. Lanzirotti, W.A. Hopkins, P.M. Bertsch, and J. Burger Application of synchrotron X-ray microbeam spectroscopy to the determination of metal distribution and speciation in biological tissues Spectrosc. Lett. 38 2005 343 363 (Pubitemid 40816291)
19. B. De Samber, R. Evens, K. De Schamphelaere, G. Silversmit, B. Masschaele, T. Schoonjans, B. Vekemans, C. Janssen, L. Van Hoorebeke, I. Szaloki, L. Balcaen, F. Vanhaecke, G. Falkenberg, and L. Vincze Combining synchrotron and laboratory X-ray techniques for studying tissue-specific trace level metal distributions in daphnia magna J. Anal. At. Spectrom. 23 2008 829 839
20. A. Carmona, P. Cloetens, G. Devs, S. Bohic, and R. Ortega Nano-imaging of trace metals by synchrotron X-ray fluorescence into dopaminergic single cells and neurite-like processes J. Anal. At. Spectrom. 23 2008 1083 1088
21. S. Chandra 3D subcellular SIMS imaging in cryogenically prepared single cells Appl. Surf. Sci. 231 2004 467 469
22. J.L. Guerquin-Kern, T.D. Wu, C. Quintana, and A. Croisy Progress in analytical imaging of the cell by dynamic secondary ion mass spectrometry (SIMS microscopy) Biochim. Biophys. Acta - Gen. Subjects 1724 2005 228 238 (Pubitemid 41080032)
23. M.A. Heeren, L.A. Mc Donnell, E. Amstalden, S.L. Luxambourgh, A.F.M. Altelaar, and S.R. Piersma Why don't biologists use SIMS? A critical evaluation of imaging MS Appl. Surf. Sci. 252 2006 6827 6835 (Pubitemid 44233813)
24. S. Chandra, W. Tjarks, D.R. Lorey, and R.F. Barth Quantitative subcellular imaging of boron compounds in individual mitotic and interphase human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS) J. Microsc. 229 2007 92 103 (Pubitemid 350292339)
25. T.G. Lee, J.W. Parka, H.K. Shona, D.W. Moon, W.W. Choib, K. Lib, and J.H. Chung Biochemical imaging of tissues by SIMS for biomedical applications Appl. Surf. Sci. 255 2008 1241 1248
26. J.A. McLean, W.B. Ridenour, and R.M. Caprioli Profiling and imaging of tissues by imaging ion mobility-mass spectrometry J. Mass Spectrom. 42 2007 1099 1105 (Pubitemid 47255462)
27. M. Stoeckli, P. Chaurand, D.E. Hallahan, and R.M. Caprioli Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues Nat. Med. 7 2001 493 496 (Pubitemid 32298555)
28. P.J. Todd, T.G. Schaaf, P. Chaurand, and R.M. Caprioli Organic ion imaging of biological tissue with secondary ion mass spectrometry and matrix-assisted laser desorption/ionization J. Mass Spectrom. 36 2001 355 369 (Pubitemid 32409879)
29. W.B. Ridenour, M. Kliman, J.A. McLean, and R.M. Caprioli Structural characterization of phospholipids and peptides directly from tissue sections by MALDI traveling-wave ion mobility-mass spectrometry Anal. Chem. 82 2010 1881 1889
30. S.R. Oppenheimer, D.M. Mi, M.E. Sanders, and R.M. Caprioli Molecular analysis of tumor margins by MALDI mass spectrometry in renal carcinoma J. Proteome Res. 9 2010 2182 2190
31. J.L. Norris, D.S. Cornett, J.A. Mobley, M. Andersson, E.H. Seeley, P. Chaurand, and R.M. Caprioli Processing MALDI mass spectra to improve mass spectral direct tissue analysis Int. J. Mass Spectrom. 260 2007 212 221
32. M. Girod, Y. Shi, J.X. Chen, and R.G. Cooks Desorption electrospray ionization imaging mass spectrometry of lipids in rat spinal cord J. Am. Soc. Mass Spectrom. 21 2010 1177 1189
33. J.M. Wiseman, D.R. Ifa, Q. Song, and R.G. Cooks Tissue imaging at atmospheric pressure using desorption electrospray ionization (DESI) mass spectrometry Angew. Chem. 43 2006 7346 7350
34. B. Wu, J.S. Becker, Chemical imaging of biological tissues and cells in the low-micrometer and nanometer range, Int. J. Mass Spectrom., this special issue.
35. R.W. Hutchinson, A.G. Cox, C.W. McLeod, P.S. Marshall, A. Harper, E.L. Dawson, and D.R. Howlett Imaging and spatial distribution of beta-amyloid peptide and metal ions in Alzheimer's plaques by laser ablation-inductively coupled plasma-mass spectrometry Anal. Biochem. 346 2005 225 233 (Pubitemid 41550254)
36. B. Jackson, S. Harper, L. Smith, and J. Flinn Elemental mapping and quantitative analysis of Cu, Zn, and Fe in rat brain sections by laser ablation ICP-MS Anal. Bioanal. Chem. 384 2006 1618 2642
37. L.A. McDonnell, S.R. Piersma, A.F.M. Altelaar, T.H. Mize, S.L. Luxembourg, P.D.E.M. Verhaert, J. van Minnen, and R.M.A. Heeren Subcellular imaging mass spectrometry of brain tissue J. Mass Spectrom. 40 2005 160 168 (Pubitemid 40330922)
38. J. Dobrowolska, M. Dehnhardt, A. Matusch, M. Zoriy, P. Koscielniak, K. Zilles, and J.S. Becker Quantitative imaging of zinc, copper and lead in three distinct regions of the human brain by laser ablation inductively coupled plasma mass spectrometry Talanta 74 2008 717 723
39. J.S Becker, M. Zoriy, B. Wu, A. Matusch, and B.J. Su Imaging of essential and toxic elements in biological tissues by LA-ICP-MS J. Anal. At. Spectrom. 23 2008 1275 1280
40. J.S. Becker, A. Matusch, C. Depboylu, J. Dobrowolska, and M. Zoriy Quantitative imaging of selenium, copper, and zinc in thin sections of biological tissues (Slugs-Genus arion) measured by laser ablation inductively coupled of plasma mass spectrometry Anal. Chem. 79 2007 6074 6080 (Pubitemid 47282316)
41. J.S. Becker, M. Zoriy, C. Pickhardt, N. Palomero-Gallagher, and K. Zilles Imaging of copper, zinc, and other elements in thin section of human brain samples (Hippocampus) by laser ablation inductively coupled plasma mass spectrometry Anal. Chem. 77 2005 3208 3216 (Pubitemid 40695477)
42. M. Dehnhardt, M. Zoriy, Z. Khan, G. Reifenberger, T.J. Ekstrom, J.S. Becker, K. Zilles, and A. Bauer Element distribution is altered in a zone surrounding human glioblastoma multiforme J. Trace Elem. Med. Biol. 22 2008 17 23 (Pubitemid 351305472)
43. M. Zoriy, M. Dehnhardt, A. Matusch, and J.S. Becker Comparative imaging of P, S, Fe, Cu, Zn and C in thin sections of rat brain tumor as well as control tissues by laser ablation inductively coupled plasma mass spectrometry Spectrochim. Acta B 63 2008 375 382
44. J.S. Becker, M. Zoriy, M. Dehnhardt, C. Pickhardt, and K. Zilles Copper, zinc, phosphorus and sulfur distribution in thin section of rat brain tissues measured by laser ablation inductively coupled plasma mass spectrometry: possibility for small-size tumor analysis J. Anal. At. Spectrom. 20 2005 912 917 (Pubitemid 41284851)
45. M. Zoriy, M. Dehnhardt, G. Reifenberger, K. Zilles, and J.S. Becker Imaging of Cu, Zn, Pb and U in human brain tumor resections by laser ablation inductively coupled plasma mass spectrometry Int. J. Mass Spectrom. 257 2006 27 33
46. L.M. Wang, J.S. Becker, Q. Wu, M.F. Oliveira, F.A. Bozza, A.L. Schwager, J.M. Hoffman, and K.A. Morton Alterations in copper uptake, content and distribution in the brains of aging mice Metallomics 2 2010 348 353
47. D. Pozebon, V. Dressler, A. Matusch, and J.S. Becker Monitoring of platinum in a single hair by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) after cisplatin Int. J. Mass Spectrom. 272 2008 57 62
48. J.S. Becker, R. Lobinski, and J.S. Becker Metal imaging in non-denaturating 2D electrophoresis gels by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) for the detection of metalloproteins Metallomics 1 2009 312 316
49. J.S. Becker, D. Pozebon, V.L. Dressler, R. Lobinski, and J.S. Becker LA-ICP-MS studies of zinc exchange by copper in bovine serum albumin using an isotopic enriched copper tracer J. Anal. At. Spectrom. 23 2008 1076 1082
50. M. Zoriy, M. Kayser, A. Izmer, and C.B.J.S. Pickhardt Determination of uranium isotopic ratios in biological samples using laser ablation inductively coupled plasma double focusing sector field mass spectrometry with cooled ablation chamber Int. J. Mass Spectrom. 242 2005 297 302 (Pubitemid 40353750)
51. J.S. Becker, U. Kumtabtim, B. Wu, P. Steinacker, M. Otto, A. Matusch, Bioimaging of metals in mouse spinal cord by laser ablation inductively coupled plasma mass spectrometry, (2011), submitted for publication.
52. J.S. Becker, S. Niehren, A. Matusch, B. Wu, H.-F. Fang, U. Kumtabtim, M. Hamester, and D. Salber Scaling down the bioimaging of metals by laser microdissection inductively coupled plasma mass spectrometry (LMD-ICP-MS) Int. J. Mass Spectrom. 294 2010 1 6
53. T. Osterholt, D. Salber, A. Matusch, J.S. Becker, C. Palm, IMAGENA: image generation and analysis - an interactive software tool handling LA-ICP-MS data, Int. J. Mass Spectrom., this issue (2011).
54. V.L. Dressler, D. Pozebon, M. Foster Mesko, A. Matusch, U. Kumtabtim, B. Wu, and J.S. Becker Biomonitoring of essential and toxic metals in single hair using on-line solution-based calibration in laser ablation inductively coupled plasma mass spectrometry Talanta 82 2010 1770 1777
55. D. Pozebon, V.L. Dressler, M.F. Mesko, A. Matusch, and J.S. Becker Bioimaging of metals in thin mouse brain section by laser ablation inductively coupled plasma mass spectrometry: novel online quantification strategy using aqueous standards J. Anal. At. Spectrom. 25 2010 1739 1744
56. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates 2007 Academic Press/Elsevier Amsterdam/Boston
57. J.S. Becker, U. Breuer, H.-F. Hsieh, T. Osterholt, U. Kumtabtim, B. Wu, A. Matusch, J.A. Caruso, and Z. Qin Bioimaging of metals and biomolecules in mouse heart by laser ablation inductively coupled plasma mass spectrometry and secondary ion mass spectrometry Anal. Chem. 82 2010 9528 9533
58. T. Kral, H. Clusmann, J. Urbach, J. Schramm, C.E. Elger, M. Kurthen, and T. Grunwald Preoperative evaluation for epilepsy surgery Zentralbl. Neurochir. 63 2002 106 110
59. M. Majores, S. Schoch, and A.B.A.J. Lie Molecular neuropathology of temporal lobe epilepsy: complementary approaches in animal models and human disease tissue Epilepsia 48 2007 4 12 (Pubitemid 46849998)
60. A. Matusch, A. Bauer, J.S. Becker, Element imaging in formalin fixed slices of human mesencephalon, Int. J. Mass Spectrom., this issue (2011).
61. B.D. Corbin, E.H. Seeley, A. Raab, J. Feldmann, M.R. Miller, V.J. Torres, K.L. Anderson, B.M. Dattilo, P.M. Dunman, R. Gerads, R.M. Caprioli, W. Nacken, W.J. Chazin, and E.P. Skaar Metal chelation and inhibition of bacterial growth in tissue abscesses Science 319 2008 962 965 (Pubitemid 351263768)
62. J.S. Becker, M. Zoriy, M. Przybylski, and J.S. Becker Study of formation of Cu- and Zn-containing tau protein using isotopic-enriched tracers by LA-ICP-MS and MALDI-FTICR-MS J. Anal. At. Spectrom. 22 2007 63 68 (Pubitemid 44975077)
63. A. Sussulini, H. Kratzin, O. Jahn, C.E. Muller Banzato, M.A.Z. Arruda, and J.S. Becker Metallomics studies of human blood serum from treated bipolar disorder patients Anal. Chem. 82 2010 5859 5864
64. B. Wu, M. Zoriy, Y. Chen, and J.S. Becker Imaging of nutrient elements in the leaves of Elsholtzia splendens by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) Talanta 78 2009 132 137
65. M.C. Santos, M. Wagner, B. Wu, J. Scheider, J. Oehlmann, S. Cadore, and J.S. Becker Biomonitoring of metal contamination in a marine prosobranch snail (Nassarius reticulatus) by imaging laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) Talanta 80 2009 423 430
66. B. Wu, Y. Chen, and J.S. Becker Study of essential element accumulation in the leaves of a Cu-tolerant plant Elsholtzia splendens after Cu stress by imaging LA-ICP-MS Anal. Chim. Acta 633 2009 165 172
67. J.S. Becker, R.C. Dietrich, A. Matusch, D. Pozebon, and V.L. Dressler Quantitative images of metals in plant tissues measured by laser ablation inductively coupled plasma mass spectrometry Spectrochim. Acta B 2008
68. J.S. Becker, A. Gorbunoff, M. Zoriy, A. Izmer, and M. Kayser Evidence of near-field laser ablation inductively coupled plasma mass spectrometry (NF-LA-ICP-MS) at nanometre scale for elemental and isotopic analysis on gels and biological samples J. Anal. At. Spectrom. 21 2006 19 25
69. M. Zoriy, and J.S. Becker Near-field laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS): A novel elemental analytical technique at nanometer scale Rapid Commun. Mass Spectrom. 23 2009 23 30
70. M. Zoriy, M. Kayser, and J.S. Becker Possibility of nano-local element analysis by near-field laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS): new experimental arrangement and first application Int. J. Mass Spectrom. 273 2008 151 155