Quantitative subcellular imaging of boron compounds in individual mitotic and interphase human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS)

Journal of Microscopy

Volumn 229, Issue 1, 2008, Pages 92-103

  Chandra, S ^a   Tjarks, W ^b   Lorey II, D R ^c   Barth, R F ^b  

^a Institute for the Study of the Continents   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c Department of Obstetrics Gynecology   (United States)

Author keywords

BNCT; Boronated nucleosides; Boronophenylalanine; Brain tumours; Freeze fracture; Imaging mass spectrometry; Intracellular potassium and sodium concentrations; Mitosis; Subcellular drug localization

Indexed keywords

BORON; CANCER CELLS; CELL MEMBRANES; CYTOLOGY; DISEASES; IONS; MAMMALS; MITOCHONDRIA; POTASSIUM; SECONDARY EMISSION; SECONDARY ION MASS SPECTROMETRY; TUMORS;

BORON NEUTRON CAPTURE THERAPY; BORON NEUTRONCAPTURE THERAPY; BORONATED NUCLEOSIDE; BORONOPHENYLALANINE; BRAIN TUMORS; FREEZE FRACTURE; IMAGING MASS SPECTROMETRY; INTRACELLULAR POTASSIUM AND SODIUM CONCENTRATION; LOCALISATION; MITOSIS; SUB-CELLULAR; SUBCELLULAR DRUG LOCALIZATION;

SODIUM;

3 [4 (2 CARBORAN 1 YL)BUTYL]THYMIDINE; 4 BORONOPHENYLALANINE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BORON DERIVATIVE; DNA; PHOSPHOTRANSFERASE; POTASSIUM; SODIUM; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL MEMBRANE; CELL NUCLEUS; CHROMOSOME; CONCENTRATION (PARAMETERS); CYTOPLASM; FREEZE DRYING; FREEZE FRACTURE; GLIOBLASTOMA; HUMAN; HUMAN CELL; INTERPHASE; MAMMAL CELL; MASS SPECTROMETRY; METAPHASE; MICROSCOPE IMAGE; MITOCHONDRION; MITOSIS; PRIORITY JOURNAL;

MAMMALIA;

EID: 37349001070     PISSN: 00222720     EISSN: 13652818     Source Type: Journal    
DOI: 10.1111/j.1365-2818.2007.01869.x     Document Type: Article

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