Production and characterization of a humanized single-chain antibody against human integrin αvβ3 protein

Journal of Biological Chemistry

Volumn 286, Issue 27, 2011, Pages 24500-24507

  Liu, Dabin ^a   Wang, Chen ^a   Li, Cun ^a   Zhang, Xin ^a   Zhang, Baozhong ^a   Mi, Zhiqiang ^a   An, Xiaoping ^a   Tong, Yigang ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; DISEASES; EPITOPES; ESCHERICHIA COLI; MAMMALS; MONOCLONAL ANTIBODIES;

ANTIGEN-BINDING ACTIVITIES; CANCER CELL GROWTH; CELL VIABILITY ASSAYS; RESISTANCE PROBLEMS; SINGLE-CHAIN ANTIBODIES; SINGLE-CHAIN FV; TRANSMEMBRANE GLYCOPROTEINS; TUMOR ANGIOGENESIS;

TUMORS;

EPITOPE; HUMANIZED SINGLE CHAIN FRAGMENT VARIABLE MONOCLONAL ANTIBODY E10; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CDR3 GENE; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; EXPRESSION VECTOR; FEMALE; GENE; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN PURIFICATION; TUMOR CELL; TUMOR XENOGRAFT;

ESCHERICHIA COLI;

EID: 79959907602     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.211847     Document Type: Article

References (33)

1. Cavallaro, U., and Christofori, G. (2000) J. Neurooncol. 50, 63-70
2. Keshet, E., and Ben-Sasson, S. A. (1999) J. Clin. Invest. 104, 1497-1501
3. Klohs, W. D., and Hamby, J. M. (1999) Curr. Opin. Biotechnol. 10, 544-549
4. Black, W. R., and Agner, R. C. (1998) Nature 391, 450
5. Rosenfeld, P. J., Rich, R. M., and Lalwani, G. A. (2006) Ophthalmol. Clin. North Am. 19, 361-372
6. Wu, L., Martínez-Castellanos, M. A., Quiroz-Mercado, H., Arevalo, J. F., Berrocal, M. H., Farah, M. E., Maia, M., Roca, J. A., and Rodriguez, F. J. (2008) Graefe's Arch. Clin. Exp. Ophthalmol. 246, 81-87
7. Hynes, R. O. (1992) Cell 69, 11-25
8. Hodivala-Dilke, K. (2008) Curr. Opin. Cell Biol. 20, 514-519
9. Brooks, P. C., Montgomery, A. M., Rosenfeld, M., Reisfeld, R. A., Hu, T., Klier, G., and Cheresh, D. A. (1994) Cell 79, 1157-1164
10. Cai, W., and Chen, X. (2006) Anticancer Agents Med. Chem. 6, 407-428
11. Landen, C. N., Kim, T. J., Lin, Y. G., Merritt, W. M., Kamat, A. A., Han, L. Y., Spannuth, W. A., Nick, A. M., Jennnings, N. B., Kinch, M. S., Tice, D., and Sood, A. K. (2008) Neoplasia 10, 1259-1267
12. Patel, S. R., Jenkins, J., Papadopolous, N., Burgess, M. A., Plager, C., Gut- terman, J., and Benjamin, R. S. (2001) Cancer 92, 1347-1348
13. Cheresh, D. A. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 6471-6475
14. Nabors, L. B., Mikkelsen, T., Rosenfeld, S. S., Hochberg, F., Akella, N. S., Fisher, J. D., Cloud, G. A., Zhang, Y., Carson, K., Wittemer, S. M., Colevas, A. D., and Grossman, S. A. (2007) J. Clin. Oncol. 25, 1651-1657
15. Reinmuth, N., Liu, W., Ahmad, S. A., Fan, F., Stoeltzing, O., Parikh, A. A., Bucana, C. D., Gallick, G. E., Nickols, M. A., Westlin, W. F., and Ellis, L. M. (2003) Cancer Res. 63, 2079-2087
16. Luk, J. M., and Wong, K. F. (2006) Clin. Exp. Pharmacol. Physiol. 33, 482-488
17. Kuan, C. T., Srivastava, N., McLendon, R. E., Marasco, W. A., Zalutsky, M. R., and Bigner, D. D. (2010) Int. J. Cancer 127, 598-611
18. Kogelberg, H., Tolner, B., Thomas, G. J., Di Cara, D., Minogue, S., Ramesh, B., Sodha, S., Marsh, D., Lowdell, M. W., Meyer, T., Begent, R. H., Hart, I., Marshall, J. F., and Chester, K. (2008) J. Mol. Biol. 382, 385-401
19. Rader, C., Cheresh, D. A., and Barbas, C. F., 3rd. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 8910-8915
20. Tsui, P., Tornetta, M. A., Ames, R. S., Silverman, C., Porter, T., Weston, C., Griego, S., and Sweet, R. W. (2002) J. Immunol. Methods 263, 123-132
21. Wu, Y., Li, Q., and Chen, X. Z. (2007) Nat. Protoc. 2, 3278-3284
22. Liu, Z., Jia, B., Zhao, H., Chen, X., and Wang, F. (2011) Mol. Imaging Biol. 13, 112-120
23. Avraamides, C. J., Garmy-Susini, B., and Varner, J. A. (2008) Nat. Rev. Cancer 8, 604-617
24. Gutheil, J. C., Campbell, T. N., Pierce, P. R., Watkins, J. D., Huse, W. D., Bodkin, D. J., and Cheresh, D. A. (2000) Clin. Cancer Res. 6, 3056-3061
25. Rader, C., Popkov, M., Neves, J. A., and Barbas, C. F., 3rd. (2002) FASEB J. 16, 2000-2002
26. Borras, L., Gunde, T., Tietz, J., Bauer, U., Hulmann-Cottier, V., Grimshaw, J. P., and Urech, D. M. (2010) J. Biol. Chem. 285, 9054-9066
27. Hedley, S. J., Auf der Maur, A., Hohn, S., Escher, D., Barberis, A., Glasgow, J. N., Douglas, J. T., Korokhov, N., and Curiel, D. T. (2006) Gene Ther. 13, 88-94
28. Pantoliano, M. W., Bird, R. E., Johnson, S., Asel, E. D., Dodd, S. W., Wood, J. F., and Hardman, K. D. (1991) Biochemistry 30, 10117-10125
29. Brereton, H. M., Chamberlain, D., Yang, R., Tea, M., McNeil, S., Coster, D. J., and Williams, K. A. (2007) J. Biotechnol. 129, 539-546
30. Mayer, M., and Buchner, J. (2004) Methods Mol. Med. 94, 239-254
31. Gräslund, S., Nordlund, P., Weigelt, J., Hallberg, B. M., Bray, J., Gileadi, O., Knapp, S., Oppermann, U., Arrowsmith, C., Hui, R., Ming, J., dhe-Paganon, S., Park, H. W., Savchenko, A., Yee, A., Edwards, A., Vincentelli, R., Cambillau, C., Kim, R., Kim, S. H., Rao, Z., Shi, Y., Terwilliger, T. C., Kim, C. Y., Hung, L. W., Waldo, G. S., Peleg, Y., Albeck, S., Unger, T., Dym, O., Prilusky, J., Sussman, J. L., Stevens, R. C., Lesley, S. A., Wilson, I. A., Joachimiak, A., Collart, F., Dementieva, I., Donnelly, M. I., Eschenfeldt, W. H., Kim, Y., Stols, L., Wu, R., Zhou, M., Burley, S. K., Emtage, J. S., Sauder, J. M., Thompson, D., Bain, K., Luz, J., Gheyi, T., Zhang, F., Atwell, S., Almo, S. C., Bonanno, J. B., Fiser, A., Swaminathan, S., Studier, F. W., Chance, M. R., Sali, A., Acton, T. B., Xiao, R., Zhao, L., Ma, L. C., Hunt, J. F., Tong, L., Cunningham, K., Inouye, M., Anderson, S., Janjua, H., Shastry, R., Ho, C. K., Wang, D., Wang, H., Jiang, M., Montelione, G. T., Stuart, D. I., Owens, R. J., Daenke, S., Schütz, A., Heinemann, U., Yokoyama, S., Büssow, K., and Gunsalus, K. C. (2008) Nat. Methods 5, 135-146
32. Yang, J., Chen, R., Wei, J., Zhang, F., Zhang, Y., Jia, L., Yan, Y., Luo, W., Cao, Y., Yao, L., Sun, J., Xu, Z., and Yang, A. (2010) Appl Microbiol. Biotechnol. 86, 1067-1075
33. Bradford, M. M. (1976) Anal. Biochem. 7, 248-254