Aerobic exercise improves reverse cholesterol transport in cholesteryl ester transfer protein transgenic mice

Lipids

Volumn 46, Issue 7, 2011, Pages 617-625

  Rocco, D D F M ^a   Okuda, L S ^a   Pinto, R S ^a   Ferreira, F D ^a   Kubo, S K ^a   Nakandakare, E R ^a   Quintao E C R ^a   Catanozi, S ^a   Passarelli, M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Atherosclerosis; CETP; Cholesterol; HDL; Physical exercise

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; CHOLESTANETRIOL 26 MONOOXYGENASE; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLESTEROL ESTER; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; SCAVENGER RECEPTOR BI;

AEROBIC EXERCISE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CHOLESTANETRIOL 26 MONOOXYGENASE GENE; CHOLESTEROL 7ALPHA MONOOXYGENASE GENE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; EXERCISE INTENSITY; FAST PROTEIN LIQUID CHROMATOGRAPHY; FECES LEVEL; GENE; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; IN VIVO STUDY; LIPID ANALYSIS; LIPID COMPOSITION; LIPID METABOLISM; MALE; MOUSE; NONHUMAN; PROTEIN CONTENT; PROTEIN FUNCTION; PROTEIN SYNTHESIS REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITTING; TISSUE DISTRIBUTION;

ANIMALS; ANTIGENS, CD36; APOLIPOPROTEIN A-I; ATHEROSCLEROSIS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CHOLESTEROL ESTER TRANSFER PROTEINS; HUMANS; LIPIDS; LIPOPROTEINS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; LIVER; MACROPHAGES; MALE; MICE; MICE, TRANSGENIC; PHYSICAL CONDITIONING, ANIMAL; RECEPTORS, LDL;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 79959906676     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-011-3555-z     Document Type: Article

References (45)

1. Lee IM, Hsieh CC, Paffenbarger RS Jr (1995) Exercise intensity and longevity in men. The Harvard Alumni Study. JAMA 273:1179-1184
2. Nordstrom CK, Dwyer KM, Merz NB, Shircore A, Dwyer JH (2003) Leisure time physical activity and early atherosclerosis: the Los Angeles atherosclerosis study. Am J Med 115:19-25 (Pubitemid 36831117)
3. Ramachandran S, Penumetcha M, Merchant NK, Santanam N, Rong R, Parthasarathy S (2005) Exercise reduces preexisting atherosclerotic lesions in LDL receptor knock out mice. Atherosclerosis 178:33-38 (Pubitemid 39600813)
4. Matsumoto Y, Adams V, Jacob S, Mangner N, Schuler G, Linke A (2010) Regular exercise training prevents aortic valve disease in low-density lipoprotein-receptor-deficient mice. Circulation 21:759-767
5. Napoli C, Williams-Ignarro S, Nigris F, Lerman LO, D'Armiento FP, Crimi E, Byrns RE, Casamassimi A, Lanza A, Gombos F, Sica V (2006) Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice. PNAS 13:10479-10484 (Pubitemid 44051192)
6. Meilhac O, Ramachandran S, Chiang K, Santanam N, Parthasarathy S (2001) Role of arterial wall antioxidant defense in beneficial effects of exercise on atherosclerosis in mice. Arterioscler Thromb Vasc Biol 21:1681-1688 (Pubitemid 34215591)
7. Wang X, Rader DJ (2007) Molecular regulation of macrophage reverse cholesterol transport. Curr Opin Cardiol 22:368-372 (Pubitemid 46897290)
8. Institute of Laboratory Animal Research CoLS (1996) National Research Council guide for the care and use of laboratory animals. In: Council NR (ed). National Academy Press, Washington (DC), p 124
9. Lowry OH, Rosebrough NJ, Farr Al, Randall RJ (1951) Protein measurement with folin phenol reagent. J Biol Chem 193:265-275
10. Basu SK, Goldstein JL, Anderson RGW, Brown MS (1976) Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous hypercholesterolemia fibroblasts. Proc Natl Acad Sci 73:3178-3182
11. Zhang Y, Zanotti I, Reilly MP, Glick JM, Rothblat GH, Rader DJ (2003) Overexpression of apolipoprotein A-1 promotes reverse transport of cholesterol from macrophages to feces in vivo. Circulation 108:661-663 (Pubitemid 36999247)
12. Folch J, Lees M, Stanley S (1957) A simple method for the isolation and purification of total lipids from animal's tissues. J Biol Chem 226:497-509
13. Escolà-Gil JC, Julve J, Marzal-Casacuberta A, Ordóñ ez-Llanos J, González-Sastre F, Blanco-Vaca F (2001) ApoA-II expression in CETP transgenic mice increases VLDL production and impairs VLDL clearance. J Lipid Res 42:241-248 (Pubitemid 32206836)
14. Gupta AK, Ross EA, Myers JN, Kashyap ML (1993) Increased reverse cholesterol transport in athletes. Metabolism 42:684-690 (Pubitemid 23173405)
15. Olchawa B, Kingwell BA, Hoang A, Schneider L, Miyazaki O, Nestel P, Sviridov D (2004) Physical fitness and reverse cholesterol transport. Arterioscler Thromb Vasc Biol 24:1087-1091 (Pubitemid 38737836)
16. Wei C, Penumetcha M, Santanam N, Liu GY, Garelnabi M, Parthasarathy S (2005) Exercise might favor reverse cholesterol transport and lipoprotein clearance: potential mechanism for its anti-atherosclerotic effects. Biochim Biophys Acta 1723:124-127 (Pubitemid 40744679)
17. Wilund KR, Feeney LA, Tomayko EJ, Chung HR, Kim K (2008) Endurance exercise training reduces gallstone development in mice. J Appl Physiol 104:761-765 (Pubitemid 351471675)
18. Wang X, Collins HL, Ranalletta M, Fuki IV, Billheimer JT, Rothblat GH, Tall AR, Rader DJ (2007) Macrophage ABCA1 and ABCG1, but not SR-BI, promote reverse cholesterol transport in vivo. J Clin Invest 117:2216-2224 (Pubitemid 47219566)
19. Zhang Y, Da Silva JR, Reilly M, Billheimer JT, Rothblat GH, Rader DJ (2005) Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo. J Clin Invest 115:2870-2874 (Pubitemid 41434414)
20. Mardones P, Quiñones V, Amigo L, Moreno M, Miquel JF, Schwarz M, Miettinen HE, Trigatti B, Krieger M, VanPatten S, Cohen DE, Rigotti A (2001) Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice. J Lipid Res 42:170-180 (Pubitemid 32206827)
21. Kozarsky KF, Donahee MH,Glick JM, Krieger M, Rader DJ (2000) Gene transfer and hepatic overexpression of the HDL receptor SRBI reduces atherosclerosis in the cholesterol-fed LDL receptordeficient mouse. Arterioscler Thromb Vasc Biol 20:721-727 (Pubitemid 30151687)
22. Gauthier A, Lau P, Zha X, Milne R, McPherson R (2005) Cholesteryl ester transfer protein directly mediates selective uptake of high density lipoprotein cholesteryl esters by the liver. Arterioscler Thromb Vasc Biol 25:2177-2184 (Pubitemid 41416318)
23. Vassiliou G, McPherson R (2004) Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes. J Lipid Res 5:1683-1693 (Pubitemid 39296208)
24. Harada LM, Amigo L, Cazita PM, Salerno AG, Rigotti AA, Quintão EC, Oliveira HC (2007) CETP expression enhances liver HDL-cholesteryl ester uptake but does not alter VLDL and biliary lipid secretion. Atherosclerosis 191:313-318 (Pubitemid 46400715)
25. Rotllan N, Calpe-Berdiel L, Guillaumet-Adkins A, Süren-Castillo S, Blanco-Vaca F, Escolà-Gil JC (2008) CETP activity variation in mice does not affect two major HDL antiatherogenic properties: macrophage-specific reverse cholesterol transport and LDL antioxidant protection. Atherosclerosis 196:505-513
26. Tchoua U, D'Souza W, Mukhamedova N, Blum D, Niesor E, Mizrahi J, Maugeais C, Sviridov D (2008) The effect of cholesteryl ester transfer protein overexpression and inhibition on reverse cholesterol transport. Cardiovascular Res 77:732-739 (Pubitemid 351301865)
27. Tanigawa H, Billheimer JT, Tohyama J, Zhang Y, Rothblat G, Rader DJ (2007) Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport. Circulation 116:1267-1273 (Pubitemid 47517538)
28. Harder C, Lau P, Meng A, Whitman SC, McPherson R (2007) Cholesteryl ester transfer protein (CETP) expression protects against diet induced atherosclerosis in SR-BI deficient mice. Arterioscler Thromb Vasc Biol 27:858-864 (Pubitemid 46606717)
29. Meissner M, Havinga R, Boverhof R, Kema I, Groen AK, Kuipers F (2010) Exercise enhances whole-body cholesterol turnover in mice. Med Sci Sports Exerc 42:1460-1468
30. Yasuda T, Grillot D, Bilheimer JT, Briand F, Delerive P, Huet S, Rader DJ (2010) Tissue-specific liver X receptor activation promotes macrophage reverse cholesterol transport in vivo. Arterioscler Thromb Vasc Biol 30(4):781-786
31. Sehayek E, Hazen SL (2008) Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages. Arterioscler Thromb Vasc Biol 28:1296-1297
32. Temel RE, Sawyer JK, Yu L, Lord C, Degirolamo C, McDaniel A, Marshall S, Wang N, Shah R, Rudel LL, Brown JM (2010) Biliary sterol secretion is not required for macrophage reverse cholesterol transport. Cell Metab 12:96-102
33. Meissner M, Nijstad N, Kuipers F, Tietge UJ (2010) Voluntary exercise increases cholesterol efflux but not macrophage reverse cholesterol transport in vivo in mice. Nutr Metab 1:54
34. Zhou H, Li Z, Silver DL, Jiang XC (2006) Cholesteryl ester transfer protein (CETP) expression enhances HDL cholesteryl ester liver delivery, which is independently of scavenger receptor BI, LDL receptor related protein and possibly LDL receptor. Biochim Biophys Acta 1761:1482-1488 (Pubitemid 44821908)
35. Calpe-Berdiel L, Rotllan N, Palomer X, Ribas V, Blanco-Vaca F, Escolà-Gil JC (2005) Direct evidence in vivo of impaired macrophage- specific reverse cholesterol transport in ATP-binding cassette transporter A1-deficient mice. Biochim Biophys Acta 1738:6-9 (Pubitemid 43122125)
36. Couillard C, Després JP, Lamarche B, Bergeron J, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C (2001) Effects of endurance exercise training on plasma HDL cholesterol levels depend on levels of triglycerides: evidence from men of the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Arterioscler Thromb Vasc Biol 21:1226-1232 (Pubitemid 34215155)
37. Mukherjee M, Shetty KR (2004) Variations in high-density lipoprotein cholesterol in relation to physical activity and Taq 1B polymorphism of the cholesteryl ester transfer protein gene. Clin Genet 65:412-418 (Pubitemid 38659712)
38. Sorlí JV, Corella D, Francés F, Ramírez JB, González JI, Guillén M, Portolés O (2006) The effect of the APOE polymorphism on HDL-C concentrations depends on the cholesterol ester transfer protein gene variation in a Southern European population. Clin Chim Acta 366:196-203
39. Basso F, Freeman L, Knapper CL, Remaley A, Stonik J, Neufeld EB, Tansey T, Amar MJ, Fruchart-Najib J, Duverger N, Santamarina- Fojo S, Brewer HB Jr (2003) J Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations. J Lipid Res 44(2):296-302
40. Wellington CL, Brunham LR, Zhou S, Singaraja RR, Visscher H, Gelfer A, Ross C, James E, Liu G, Huber MT, Yang YZ, Parks RJ, Groen A, Fruchart-Najib J, Hayden MR (2003) Alterations of plasma lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1. J Lipid Res 44(2):1470-1480 (Pubitemid 37279591)
41. Timmins JM, Lee JY, Boudyguina E, Kluckman KD, Brunham LR, Mulya A, Gebre AK, Coutinho JM, Colvin PL, Smith TL, Hayden MR, Maeda N, Parks JS (2005) Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I. J Clin Invest 115(5): 1333-1342 (Pubitemid 40629053)
42. Singaraja RR, Stahmer B, Brundert M, Merkel M, Heeren J, Bissada N, Kang M, Timmins JM, Ramakrishnan R, Parks JS, Hayden MR, Rinninger F (2006) Hepatic ATP-binding cassette transporter A1 is a key molecule in high-density proprotein cholesteryl ester metabolism in mice. Arterioscler Thromb Vasc Biol 26(8):1821-1827 (Pubitemid 44305336)
43. Ghanbari-Niaki A, Khabazian BM, Hossaini-Kakhak SA, Rahbarizadeh F, Hedayati M (2007) Treadmill exercise enhances ABCA1 expression in rat liver. Biochem Biophys Res Commun 361:841-846 (Pubitemid 47259016)
44. Butcher LR, Thomas A, Backx K, Roberts A, Webb R, Morris K (2008) Low-intensity exercise exerts beneficial effects on plasma lipids via PPARgamma. Med Sci Sports Exerc 40:1263-1270
45. Okabe TA, Shimada K, Hattori M, Murayama T, Yokode M, Kita T, Kishimoto C (2007) Swimming reduces the severity of atherosclerosis in apolipoprotein E deficient mice by antioxidant effects. Cardiovasc Res 74:537-545 (Pubitemid 46693709)