Detection of single nucleotide polymorphism using tension-dependent stochastic behavior of a single-molecule template

Journal of the American Chemical Society

Volumn 133, Issue 26, 2011, Pages 9988-9991

  Koirala, Deepak ^a   Yu, Zhongbo ^a   Dhakal, Soma ^a   Mao, Hanbin ^a  

^a KENT STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMERS; CORONARY HEART DISEASE; DETECTABLE SIGNAL; ENSEMBLE AVERAGING; ENSEMBLE-AVERAGED; GENE FUNCTION; GENETIC VARIATION; HIGH SPECIFICITY; HIGHLY SENSITIVE; IN-SITU; LASER-TWEEZERS; MECHANICAL SIGNALS; MICROFLUIDIC PLATFORMS; PHENOTYPIC VARIATIONS; PROOF OF CONCEPT; SINGLE MUTATION; SINGLE-MOLECULE; SINGLE-NUCLEOTIDE POLYMORPHISMS; SPECIFIC RECOGNITION; STOCHASTIC BEHAVIOR; WILD TYPES;

BIOSENSORS; DIAGNOSIS; GENE THERAPY; MICROFLUIDICS; NUCLEOTIDES; PROBES; STOCHASTIC SYSTEMS;

SIGNAL DETECTION;

APTAMER;

ARTICLE; BIOSENSOR; GENE AMPLIFICATION; GENE MUTATION; ISCHEMIC HEART DISEASE; MICROFLUIDICS; MOLECULE; OPTICAL TWEEZERS; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; STOCHASTIC MODEL; TENSION DEPENDENT STOCHASTIC BEHAVIOR; WILD TYPE;

BASE SEQUENCE; BIOSENSING TECHNIQUES; DNA; MECHANICAL PROCESSES; MICROFLUIDIC ANALYTICAL TECHNIQUES; OLIGODEOXYRIBONUCLEOTIDES; OPTICAL TWEEZERS; POLYMORPHISM, SINGLE NUCLEOTIDE; STOCHASTIC PROCESSES;

EID: 79959861867     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja201976r     Document Type: Article

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