Impact of food restriction and cocaine on locomotion in ghrelin- and ghrelin-receptor knockout mice

Addiction Biology

Volumn 16, Issue 3, 2011, Pages 386-392

  Clifford, Shane ^a   Zeckler, Rosie Albarran ^b   Buckman, Sam ^a   Thompson, Jeff ^a   Hart, Nigel ^a   Wellman, Paul J ^a,b   Smith, Roy G ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Food intake; Ghrelin; Locomotion; Mice; Psychostimulants; Reinforcement

Indexed keywords

COCAINE; GHRELIN; GHRELIN RECEPTOR; GROWTH HORMONE SECRETAGOGUE RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CALORIC INTAKE; LOCOMOTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; ANTICIPATION, PSYCHOLOGICAL; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; COCAINE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; FOOD DEPRIVATION; GHRELIN; LOCOMOTION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTIVATION; RECEPTORS, GHRELIN;

EID: 79959835917     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/j.1369-1600.2010.00253.x     Document Type: Article

References (41)

1. Abizaid A (2009) Ghrelin and dopamine: new insights on the peripheral regulation of appetite. J Neuroendocrinol 21:787-793.
2. Abizaid A, Liu ZW, Andrews ZB, Shanabrough M, Borok E, Elsworth JD, Roth RH, Sleeman MW, Picciotto MR, Tschop MH, Gao XB, Horvath TL (2006) Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. J Clin Invest 116:3229-3239. (Pubitemid 44878637)
3. Abrahamsen GC, Berman Y, Carr KD (1995) Curve-shift analysis of self-stimulation in food-restricted rats: relationship between daily meal, plasma corticosterone and reward sensitization. Brain Res 695:186-194.
4. Banks WA, Burney BO, Robinson SM (2008) Effects of triglycerides, obesity, and starvation on ghrelin transport across the blood-brain barrier. Peptides 29:2061-2065.
5. Banks WA, Tschop M, Robinson SM, Heiman ML (2002) Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. J Pharmacol Exp Ther 302:822-827. (Pubitemid 34787253)
6. Bardo MT, Bevins RA (2000) Conditioned place preference: what does it add to our preclinical understanding of drug reward? Psychopharmacology 153:31-43.
7. Bell SM, Stewart RB, Thompson SC, Meisch RA (1997) Food-deprivation increases cocaine-induced conditioned place preference and locomotor activity in rats. Psychopharmacology 131:1-8. (Pubitemid 27242848)
8. Blum ID, Patterson Z, Khazall R, Lamont EW, Sleeman MW, Horvath TL, Abizaid A (2009) Reduced anticipatory locomotor responses to scheduled meals in ghrelin receptor deficient mice. Neuroscience.
9. Cabeza De Vaca S, Holiman S, Carr KD (1998) A search for the metabolic signal that sensitizes lateral hypothalamic selfstimulation in food-restricted rats. Physiol Behav 64:251-260. (Pubitemid 28458945)
10. Campbell BA, Baez LA (1974) Dissociation of arousal and regulatory behaviors following lesions of the lateral hypothalamus. J Comp Physiol Psychol 87:142-149.
11. Carr KD (2002) Augmentation of drug reward by chronic food restriction: behavioral evidence and underlying mechanisms. Physiol Behav 76:353-364.
12. Carroll ME (1985) The role of food deprivation in the maintenance and reinstatement of cocaine-seeking behavior in rats. Drug Alcohol Depend 16:95-109.
13. Carroll ME, Meisch RA (1981) Determinants of increased drug self-administration due to food deprivation. Psychopharmacology 74:197-200. (Pubitemid 11034570)
14. Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS (2001) A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50:1714-1719. (Pubitemid 33641587)
15. Davis KW, Wellman PJ, Clifford PS (2007) Augmented cocaine conditioned place preference in rats pretreated with systemic ghrelin. Regul Pept 140:148-152. (Pubitemid 46418913)
16. Diano S, Farr SA, Benoit SC, McNay EC, da Silva I, Horvath B, Gaskin FS, Nonaka N, Jaeger LB, Banks WA, Morley JE, Pinto S, Sherwin RS, Xu L, Yamada KA, Sleeman MW, Tschop MH, Horvath TL (2006) Ghrelin controls hippocampal spine synapse density and memory performance. Nat Neurosci 9:381-388. (Pubitemid 43290968)
17. Fulton S, Woodside B, Shizgal P (2000) Modulation of brain reward circuitry by leptin. Science 287:125-128.
18. Guan XM, Yu H, Palyha OC, McKee KK, Feighner SD, Sirinathsinghji DJ, Smith RG, Van der Ploeg LH, Howard AD (1997) Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues. Brain Res Mol Brain Res 48:23-29. (Pubitemid 27298124)
19. Hosoda H, Kojima M, Kangawa K (2006) Biological, physiological, and pharmacological aspects of ghrelin. J Pharmacol Sci 100:398-410. (Pubitemid 44609531)
20. Jamieson J (2004) Analysis of covariance (ANCOVA) with difference scores. Int J Psychophysiol 52:277-283.
21. Jerlhag E, Egecioglu E, Landgren S, Salome N, Heilig M, Moechars D, Datta R, Perrissoud D, Dickson SL, Engel JA (2009) Requirement of central ghrelin signaling for alcohol reward. Proc Natl Acad Sci U S A 106:11318-11323.
22. Keen-Rhinehart E, Bartness TJ (2005) Peripheral ghrelin injections stimulate food intake, foraging, and food hoarding in Siberian hamsters. Am J Physiol Regul Integr Comp Physiol.
23. Kirk RE (1982) Experimental Design. Belmont, CA:Wadsworth.
24. Kojima M, Kangawa K (2005) Ghrelin: structure and function. Physiol Rev 85:495-522. (Pubitemid 40404635)
25. LeSauter J, Hoque N, Weintraub M, Pfaff DW, Silver R (2009) Stomach ghrelin-secreting cells as food-entrainable circadian clocks. Proc Natl Acad Sci U S A 106:13582-13587.
26. Moorcroft WH, Lytle LD, Campbell BA (1971) Ontogeny of starvation-induced behavioral arousal in the rat. J Comp Physiol Psychol 75:59-67.
27. Murakami N, Hayashida T, Kuroiwa T, Nakahara K, Ida T, Mondal MS, Nakazato M, Kojima M, Kangawa K (2002) Role for central ghrelin in food intake and secretion profile of stomach ghrelin in rats. J Endocrinol 174:283-288. (Pubitemid 34965767)
28. Naleid AM, Grace MK, Cummings DE, Levine AS (2005) Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. Peptides 26:2274-2279. (Pubitemid 41584095)
29. Olds J, Milner P (1954) Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. J Comp Physiol Psychol 47:419-427.
30. Perello M, Sakata I, Birnbaum S, Chuang JC, Osborne-Lawrence S, Rovinsky SA, Woloszyn J, Yanagisawa M, Lutter M, Zigman JM (2010) Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent manner. Biol Psychiatry 67:880-886.
31. Quarta D, Di Francesco C, Melotto S, Mangiarini L, Heidbreder C, Hedou G (2009) Systemic administration of ghrelin increases extracellular dopamine in the shell but not the core subdivision of the nucleus accumbens. Neurochem Int 54:89-94.
32. Sanberg PR, Zoloty SA, Willis R, Ticarich CD, Rhoads K, Nagy RP, Mitchell SG, Laforest AR, Jenks JA, Harkabus LJ (1987) Digiscan activity: automated measurement of thigmotactic and stereotypic behavior in rats. Pharmacol Biochem Behav 27:569-572. (Pubitemid 17107033)
33. Shimbara T, Mondal MS, Kawagoe T, Toshinai K, Koda S, Yamaguchi H, Date Y, Nakazato M (2004) Central administration of ghrelin preferentially enhances fat ingestion. Neurosci Lett 369:75-79. (Pubitemid 39369506)
34. Sun Y, Ahmed S, Smith RG (2003) Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol 23:7973-7981. (Pubitemid 37377491)
35. Sun Y, Butte NF, Garcia JM, Smith RG (2008) Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance. Endocrinology 149: 843-850. (Pubitemid 351159337)
36. Szentirmai E, Kapas L, Sun Y, Smith RG, Krueger JM (2010) Restricted Feeding-Induced Sleep, Activity and Body Temperature Changes in Normal and Preproghrelin DeficientMice.Am J Physiol Regul Integr Comp Physiol 298:R(467-477).
37. Toshinai K, Mondal MS, Nakazato M, Date Y, Murakami N, Kojima M, Kangawa K, Matsukura S (2001) Upregulation of Ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration. Biochem Biophys Res Commun 281:1220-1225. (Pubitemid 32924549)
38. Wang T, Hung CC, Randall DJ (2006) The comparative physiology of food deprivation: from feast to famine. Annu Rev Physiol 68:223-251.
39. Wellman PJ, Davis KW, Nation JR (2005) Augmentation of cocaine hyperactivity in rats by systemic ghrelin. Regul Pept 125:151-154. (Pubitemid 39593719)
40. Wellman PJ, Hollas CN, Elliott AE (2008) Systemic ghrelin sensitizes cocaine-induced hyperlocomotion in rats. Regul Pept 146:33-37.
41. Wise RA (1996) Addictive drugs and brain stimulation reward. Annu Rev Neurosci 19:319-340.