Biotherapeutic target or sink: Analysis of the macrophage mannose receptor tissue distribution in murine models of lysosomal storage diseases

Journal of Inherited Metabolic Disease

Volumn 34, Issue 3, 2011, Pages 795-809

  Zhang, Xin Sheen ^a   Brondyk, William ^a   Lydon, John T ^a   Thurberg, Beth L ^a   Piepenhagen, Peter A ^a  

^a GENZYME CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROPHAGE MANNOSE RECEPTOR; MANNOSE RECEPTOR; POLYCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIAPHRAGM; FABRY DISEASE; GLYCOGEN STORAGE DISEASE TYPE 2; HEART; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; KIDNEY PARENCHYMA; LIVER PARENCHYMA; LUNG PARENCHYMA; LYSOSOME STORAGE DISEASE; MOUSE; NIEMANN PICK DISEASE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; QUADRICEPS FEMORIS MUSCLE; RECEPTOR OCCUPANCY; SPLEEN; TISSUE DISTRIBUTION; TRICEPS BRACHII MUSCLE; WILD TYPE;

ANIMALS; ANTIBODIES; ANTIBODY FORMATION; CELL LINE; DISEASE MODELS, ANIMAL; DRUG DISCOVERY; HUMANS; LECTINS, C-TYPE; LIVER; LYSOSOMAL STORAGE DISEASES; MACROPHAGES; MANNOSE-BINDING LECTINS; MICE; MICE, KNOCKOUT; MOLECULAR TARGETED THERAPY; MUSCLES; RECEPTORS, CELL SURFACE; SPLEEN; TISSUE DISTRIBUTION;

EID: 79959778157     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-011-9285-9     Document Type: Article

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