-
2
-
-
0000216808
-
Gaucher disease
-
Scriver C.R., Valle D., Beaudet A., and Sly W.S. (Eds), McGraw-Hill, New York
-
Beutler E., and Grabowski G.A. Gaucher disease. In: Scriver C.R., Valle D., Beaudet A., and Sly W.S. (Eds). The Metabolic and Molecular Bases of Inherited Disease (2001), McGraw-Hill, New York 3635-3668
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease
, pp. 3635-3668
-
-
Beutler, E.1
Grabowski, G.A.2
-
3
-
-
17644422131
-
Gaucher disease: pathological mechanisms and modern management
-
Jmoudiak M., and Futerman A.H. Gaucher disease: pathological mechanisms and modern management. Br. J. Haematol. 129 (2005) 178-188
-
(2005)
Br. J. Haematol.
, vol.129
, pp. 178-188
-
-
Jmoudiak, M.1
Futerman, A.H.2
-
5
-
-
0023840304
-
Active site directed inhibition of a cytosolic beta-glucosidase from calf liver by bromoconduritol B epoxide and bromoconduritol F
-
Legler G., and Bieberich E. Active site directed inhibition of a cytosolic beta-glucosidase from calf liver by bromoconduritol B epoxide and bromoconduritol F. Arch. Biochem. Biophys. 260 (1988) 437-442
-
(1988)
Arch. Biochem. Biophys.
, vol.260
, pp. 437-442
-
-
Legler, G.1
Bieberich, E.2
-
6
-
-
21244456941
-
X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease
-
Premkumar L., Sawkar A.R., Boldin-Adamsky S., Toker L., Silman I., Kelly J.W., Futerman A.H., and Sussman J.L. X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease. J. Biol. Chem. 280 (2005) 23815-23819
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23815-23819
-
-
Premkumar, L.1
Sawkar, A.R.2
Boldin-Adamsky, S.3
Toker, L.4
Silman, I.5
Kelly, J.W.6
Futerman, A.H.7
Sussman, J.L.8
-
7
-
-
0023917082
-
Gaucher-like changes in human blood-derived macrophages induced by beta-glucocerebrosidase inhibition
-
Yatziv S., Newburg D.S., Livni N., Barfi G., and Kolodny E.H. Gaucher-like changes in human blood-derived macrophages induced by beta-glucocerebrosidase inhibition. J. Lab. Clin. Med. 111 (1988) 416-420
-
(1988)
J. Lab. Clin. Med.
, vol.111
, pp. 416-420
-
-
Yatziv, S.1
Newburg, D.S.2
Livni, N.3
Barfi, G.4
Kolodny, E.H.5
-
8
-
-
0023820535
-
Macrophages exposed in vitro to conduritol B epoxide resemble Gaucher cells
-
Newburg D.S., Shea T.B., Yatziv S., Raghavan S.S., and McCluer R.H. Macrophages exposed in vitro to conduritol B epoxide resemble Gaucher cells. Exp. Mol. Pathol. 48 (1988) 317-323
-
(1988)
Exp. Mol. Pathol.
, vol.48
, pp. 317-323
-
-
Newburg, D.S.1
Shea, T.B.2
Yatziv, S.3
Raghavan, S.S.4
McCluer, R.H.5
-
9
-
-
0028933977
-
A regulatory role for sphingolipids in neuronal growth. Inhibition of sphingolipid synthesis and degradation have opposite effects on axonal branching
-
Schwarz A., Rapaport E., Hirschberg K., and Futerman A.H. A regulatory role for sphingolipids in neuronal growth. Inhibition of sphingolipid synthesis and degradation have opposite effects on axonal branching. J. Biol. Chem. 270 (1995) 10990-10998
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 10990-10998
-
-
Schwarz, A.1
Rapaport, E.2
Hirschberg, K.3
Futerman, A.H.4
-
10
-
-
2942675199
-
Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes
-
Trajkovic-Bodennec S., Bodennec J., and Futerman A.H. Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes. Blood Cells Mol. Diseases 33 (2004) 77-82
-
(2004)
Blood Cells Mol. Diseases
, vol.33
, pp. 77-82
-
-
Trajkovic-Bodennec, S.1
Bodennec, J.2
Futerman, A.H.3
-
11
-
-
0036832286
-
Phosphatidylcholine synthesis is elevated in neuronal models of Gaucher disease due to direct activation of CTP:phosphocholine cytidylyltransferase by glucosylceramide
-
Bodennec J., Pelled D., Riebeling C., Trajkovic S., and Futerman A.H. Phosphatidylcholine synthesis is elevated in neuronal models of Gaucher disease due to direct activation of CTP:phosphocholine cytidylyltransferase by glucosylceramide. FASEB J. 16 (2002) 1814-1816
-
(2002)
FASEB J.
, vol.16
, pp. 1814-1816
-
-
Bodennec, J.1
Pelled, D.2
Riebeling, C.3
Trajkovic, S.4
Futerman, A.H.5
-
12
-
-
12544260246
-
CTP:phosphocholine cytidylyltransferase: paving the way from gene to membrane
-
Jackowski S., and Fagone P. CTP:phosphocholine cytidylyltransferase: paving the way from gene to membrane. J. Biol. Chem. 280 (2005) 853-856
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 853-856
-
-
Jackowski, S.1
Fagone, P.2
-
13
-
-
0031553042
-
CTP:phosphocholine cytidylyltransferase
-
Kent C. CTP:phosphocholine cytidylyltransferase. Biochim. Biophys. Acta 1348 (1997) 79-90
-
(1997)
Biochim. Biophys. Acta
, vol.1348
, pp. 79-90
-
-
Kent, C.1
-
14
-
-
0034634673
-
Macrophages deficient in CTP:phosphocholine cytidylyltransferase-alpha are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death. Molecular genetic evidence that the induction of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response
-
Zhang D., Tang W., Yao P.M., Yang C., Xie B., Jackowski S., and Tabas I. Macrophages deficient in CTP:phosphocholine cytidylyltransferase-alpha are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death. Molecular genetic evidence that the induction of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response. J. Biol. Chem. 275 (2000) 35368-35376
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35368-35376
-
-
Zhang, D.1
Tang, W.2
Yao, P.M.3
Yang, C.4
Xie, B.5
Jackowski, S.6
Tabas, I.7
-
15
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
-
Clausen B.E., Burkhardt C., Reith W., Renkawitz R., and Forster I. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8 (1999) 265-277
-
(1999)
Transgenic Res.
, vol.8
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
Renkawitz, R.4
Forster, I.5
-
16
-
-
0031852098
-
A novel one-step, highly sensitive fluorometric assay to evaluate cell-mediated cytotoxicity
-
Nociari M.M., Shalev A., Benias P., and Russo C. A novel one-step, highly sensitive fluorometric assay to evaluate cell-mediated cytotoxicity. J. Immunol. Methods 213 (1998) 157-167
-
(1998)
J. Immunol. Methods
, vol.213
, pp. 157-167
-
-
Nociari, M.M.1
Shalev, A.2
Benias, P.3
Russo, C.4
-
17
-
-
0025610139
-
Regulation of phosphatidylcholine biosynthesis
-
Kent C. Regulation of phosphatidylcholine biosynthesis. Prog. Lipid Res. 29 (1990) 87-105
-
(1990)
Prog. Lipid Res.
, vol.29
, pp. 87-105
-
-
Kent, C.1
-
18
-
-
0031308388
-
Gaucher's disease. Pathological features
-
Zimran A. (Ed)
-
Pastores G.M. Gaucher's disease. Pathological features. In: Zimran A. (Ed). Bailliere's Clin. Haematol. (1997) 739-749
-
(1997)
Bailliere's Clin. Haematol.
, pp. 739-749
-
-
Pastores, G.M.1
-
19
-
-
0018590355
-
Cytological characteristics of bone marrow reticular cells, tissue macrophages and monocytic cell line
-
Kojima M., and Sato T. Cytological characteristics of bone marrow reticular cells, tissue macrophages and monocytic cell line. Adv. Exp. Med. Biol. 121 (1979) 195-209
-
(1979)
Adv. Exp. Med. Biol.
, vol.121
, pp. 195-209
-
-
Kojima, M.1
Sato, T.2
-
21
-
-
0142010564
-
Simultaneous quantification of lyso-neutral glycosphingolipids and neutral glycosphingolipids by N-acetylation with [3H]acetic anhydride
-
Bodennec J., Trajkovic-Bodennec S., and Futerman A.H. Simultaneous quantification of lyso-neutral glycosphingolipids and neutral glycosphingolipids by N-acetylation with [3H]acetic anhydride. J. Lipid Res. 44 (2003) 1413-1419
-
(2003)
J. Lipid Res.
, vol.44
, pp. 1413-1419
-
-
Bodennec, J.1
Trajkovic-Bodennec, S.2
Futerman, A.H.3
-
22
-
-
0038607434
-
Glucosylceramide and glucosylsphingosine modulate calcium mobilization from brain microsomes via different mechanisms
-
Lloyd-Evans E., Pelled D., Riebeling C., Bodennec J., de-Morgan A., Waller H., Schiffmann R., and Futerman A.H. Glucosylceramide and glucosylsphingosine modulate calcium mobilization from brain microsomes via different mechanisms. J. Biol. Chem. 278 (2003) 23594-23599
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23594-23599
-
-
Lloyd-Evans, E.1
Pelled, D.2
Riebeling, C.3
Bodennec, J.4
de-Morgan, A.5
Waller, H.6
Schiffmann, R.7
Futerman, A.H.8
-
23
-
-
11844278539
-
Enhanced calcium release in the acute neuronopathic form of Gaucher disease
-
Pelled D., Trajkovic-Bodennec S., Lloyd-Evans E., Sidransky E., Schiffmann R., and Futerman A.H. Enhanced calcium release in the acute neuronopathic form of Gaucher disease. Neurobiol. Dis. 18 (2005) 83-88
-
(2005)
Neurobiol. Dis.
, vol.18
, pp. 83-88
-
-
Pelled, D.1
Trajkovic-Bodennec, S.2
Lloyd-Evans, E.3
Sidransky, E.4
Schiffmann, R.5
Futerman, A.H.6
-
24
-
-
0028206482
-
Free cholesterol loading of macrophages stimulates phosphatidylcholine biosynthesis and up-regulation of CTP:phosphocholine cytidylyltransferase
-
Shiratori Y., Okwu A.K., and Tabas I. Free cholesterol loading of macrophages stimulates phosphatidylcholine biosynthesis and up-regulation of CTP:phosphocholine cytidylyltransferase. J. Biol. Chem. 269 (1994) 11337-11348
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 11337-11348
-
-
Shiratori, Y.1
Okwu, A.K.2
Tabas, I.3
-
25
-
-
0036920192
-
Expression of G2A, a receptor for lysophosphatidylcholine, by macrophages in murine, rabbit, and human atherosclerotic plaques
-
Rikitake Y., Hirata K., Yamashita T., Iwai K., Kobayashi S., Itoh H., Ozaki M., Ejiri J., Shiomi M., Inoue N., Kawashima S., and Yokoyama M. Expression of G2A, a receptor for lysophosphatidylcholine, by macrophages in murine, rabbit, and human atherosclerotic plaques. Arterioscler. Thromb. Vasc. Biol. 22 (2002) 2049-2053
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 2049-2053
-
-
Rikitake, Y.1
Hirata, K.2
Yamashita, T.3
Iwai, K.4
Kobayashi, S.5
Itoh, H.6
Ozaki, M.7
Ejiri, J.8
Shiomi, M.9
Inoue, N.10
Kawashima, S.11
Yokoyama, M.12
-
26
-
-
12844261591
-
Gi-independent macrophage chemotaxis to lysophosphatidylcholine via the immunoregulatory GPCR G2A
-
Yang L.V., Radu C.G., Wang L., Riedinger M., and Witte O.N. Gi-independent macrophage chemotaxis to lysophosphatidylcholine via the immunoregulatory GPCR G2A. Blood 105 (2005) 1127-1134
-
(2005)
Blood
, vol.105
, pp. 1127-1134
-
-
Yang, L.V.1
Radu, C.G.2
Wang, L.3
Riedinger, M.4
Witte, O.N.5
-
27
-
-
0035958728
-
Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A
-
Kabarowski J.H., Zhu K., Le L.Q., Witte O.N., and Xu Y. Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A. Science 293 (2001) 702-705
-
(2001)
Science
, vol.293
, pp. 702-705
-
-
Kabarowski, J.H.1
Zhu, K.2
Le, L.Q.3
Witte, O.N.4
Xu, Y.5
-
28
-
-
33749062163
-
Genetic diseases of sphingolipid metabolism: pathological mechanisms and therapeutic options
-
Kacher Y., and Futerman A.H. Genetic diseases of sphingolipid metabolism: pathological mechanisms and therapeutic options. FEBS Lett. 580 (2006) 5510-5517
-
(2006)
FEBS Lett.
, vol.580
, pp. 5510-5517
-
-
Kacher, Y.1
Futerman, A.H.2
|