Lysosomal acid α-glucosidase consists of four different peptides processed from a single chain precursor

Journal of Biological Chemistry

Volumn 280, Issue 8, 2005, Pages 6780-6791

  Moreland, Rodney J ^a   Jin, Xiaoying ^b   Zhang, X Kate ^b   Decker, Roger W ^a   Albee, Karen L ^b   Lee, Karen L ^b   Cauthron, Robert D ^a   Brewer, Kevin ^a   Edmunds, Tim ^b   Canfield, William M ^a  

^a GENZYME CORPORATION   (United States)

^b GENZYME CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BIOSYNTHESIS; CARBOHYDRATES; DATA REDUCTION; DISEASES; POLYPEPTIDES;

FIBROBLASTS; LYSOSOMAL ENZYME ACID Α-GLUCOSIDASE (GAA); LYSOSOMES; MOLECULAR MASS;

ENZYMES;

AMINO ACID; CARBOHYDRATE; GLUCAN 1,4 ALPHA GLUCOSIDASE; MANNOSE 6 PHOSPHATE; POLYPEPTIDE; PROTEIN PRECURSOR; RECOMBINANT ENZYME; SOMATOMEDIN B RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; FIBROBLAST; GLYCOGEN STORAGE DISEASE TYPE 2; HAMSTER; HUMAN; LYSOSOME; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; RABBIT;

ALPHA-GLUCOSIDASES; AMINO ACID SEQUENCE; FEMALE; FIBROBLASTS; GLUCAN 1,4-ALPHA-GLUCOSIDASE; GLYCOGEN STORAGE DISEASE TYPE II; HUMANS; MULTIENZYME COMPLEXES; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; PLACENTA; PROTEIN PRECURSORS; PROTEIN SUBUNITS; RECEPTOR, IGF TYPE 2; SEQUENCE ALIGNMENT;

EID: 20044387607     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M404008200     Document Type: Article

References (32)

1. Hoefsloot, L., Hoogeveen-Westerveld, M., Kroos, M. A., van Beeumen, J., Reuser, A. J., and Oostra, B. A. (1988) EMBO J. 7, 1697-1704
2. Hasilik, A., and Neufeld, E. F. (1980) J. Biol. Chem. 255, 4937-4945
3. Wisselaar, H. A., Kroos, M. A., Hermans, M. M., van Beeumen, J., and Reuser, A. J. (1993) J. Biol. Chem. 268, 2223-2231
4. Reuser, A. J., Kroos, M. A., Ponne, N. J., Wolterman, R. A., Loonen, M. C., Busch, H. F., Visser, W. J., and Bolhuis, P. A. (1984) Exp. Cell Res. 155, 178-189
5. Scheibe, R., Wenzel, K. W., and Hofmann, E. (1985) Biomed. Biochim. Acta 44, 1279-1286
6. Tashiro, K., Iwamasa, T., Kato, H., Ogata, S., and Anai, M. (1986) J. Biochem. 99, 693-701
7. Murray, A. K., Brown, B. I., and Brown, D. H. (1978) Arch. Biochem. Biophys. 185, 511-524
8. Matsui, H., Sasaki, M., Takemasa, E., Kaneta, T., and Chiba, S. (1984) J. Biochem. 96, 993-1004
9. Chambers, J. P., and Williams, J. C. (1983) Enzyme 29, 109-119
10. Oude Elferink, R. P., Brouwer-Kelder, E. M., Surya, I., Strijland, A., Kroos, M., Reuser, A. J., and Tager, J. M. (1984) Eur. J. Biochem. 139, 489-495
11. Radin, N. S., Shukla, A., Shukla, G. S., and Sano, A. (1989) Biochem. J. 264, 845-849
12. Raben, N., Nagaraju, K., Lee, E., Kessler, P., Byrne, B., Lee, L., LaMarca, M., King, C., Ward, J., Sauer, B., and Plotz, P. (1998) J. Biol. Chem. 273, 19086-19092
13. Bijvoet, A. G. A., Van Hurtim, H., Kroos, M. A., Van de Kamp, E. H. M., Schoneveld, O., Visser, P., Brakenhoff, J. P. J., Weggeman, M., van Corven, E. J., Van der Ploeg, A. T., and Reuser, A. J. J. (1999) Hum. Mol. Genet. 8, 2145-2153
14. Martiniuk, F., Honig, J., and Hirschorn, R. (1984) Arch. Biochem. Biophys. 231, 454-460
15. Martiniuk, F., Chen, A., Donnabella, V., Arvanitopoulos, E., Slonim, A. E., Raben, N., Plotz, P., and Rom, W. N. (2000) Biochem. Biophys. Res. Commun. 276, 917-923
16. Hirschhorn, R., Huie, M. L., and Kasper, J. S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13642-13646
17. Bijvoet, A. G. A., Kroos, M. A., Pieper, F. R., Van der Vliet, M., De Boer, H. A., Van der Ploeg, A. T., Verbeet, M. P., and Reuser, A. J. J. (1998) Hum. Mol. Genet. 7, 1815-1824
18. Mutsaers, J. H. G. M., Halbeek, H. V., Vliegenthart, J. F. G., Tager, J. M., Reuser, A. J. J., Kroos, M. A., and Galjaard, H. (1987) Biochim. Biophys. Acta 911, 244-251
19. Hirschorn, R., and Reuser, A. J. J. in The Metabolic & Molecular Bases of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., and Valle, D., eds), Eigth Edition Ed., pp. 3389-3420, III vols., McGraw-Hill, New York
20. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85
21. Blum, H., Beier, H., and Gross, H. (1987) Electrophoresis 93-99
22. Qiu, H., Edmunds, T., Baker-Malcolm, J., Karey, K. P., Estes, S., Schwarz, C., Hughes, H., and Van Patten, S. M. (2003) J. Biol. Chem. 278, 32744-32752
23. Van Hove, J. L., Yang, H. W., Oliver, L. M., Pennybacker, M. F., and Chen, Y. T. (1997) Biochem. Mol. Biol. Int. 43, 613-623
24. Altschul, S. F., and Gish, W. (1996) Methods Enzymol. 266, 460-480
25. Van Hove, J. L. K., Yang, H. W., Wu, J. Y., Brady, R. O., and Chen, Y. T. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 65-70
26. Maley, F., Trimble, R., Tarentino, A., and Plummer, T. (1989) Anal. Biochem. 180, 195-204
27. Nilssen, O., Berg, T., Riise, H. M. F., Ramachandran, U., Evjen, G., Hansen, G. M., Malm, D., Tranebjaerg, L., and Tollersrud, O. K. (1997) Hum. Mol. Genet. 6, 717-726
28. Swallow, D., Corney, G., Harris, H., and Hirschhorn, R. (1975) Ann. Hum. Genet 38, 391-406
29. Boerkoel, C. F., Exelbert, R., Nicastri, C., Nichols, R. C., Miller, F. W., Plotz, P. H., and Raben, N. (1995) Am. J. Hum. Genet. 56, 887-897
30. Hermans, M. M. P., De Graaff, E., Kroos, M. A., Wisselaar, H. A., Willemsen, R., Oostra, B. A., and Reuser, A. J. J. (1993) Biochem. J. 289, 687-693
31. Bijvoet, A. G. A., Van de Kamp, E. H. M., Kroos, M. A., Ding, J. H., Yang, B. Z., Visser, P., Bakker, C. E., Verbeet, M. P., Oostra, B. A., Reuser, A. J. J., and Van der Ploeg, A. T. (1998) Hum. Mol. Genet. 7, 53-62
32. Canfield, W. M. (November 4, 2003) U. S. Patent 6,642,038