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Volumn 34, Issue SUPPL. 2, 2011, Pages

Antimicrobial-sensing proteins in obesity and type 2 diabetes: The buffering efficiency hypothesis

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA DEFENSIN; BACTERICIDAL PERMEABILITY INCREASING PROTEIN; BIOLOGICAL MARKER; BUFFER; INSULIN; INSULIN RECEPTOR; LACTOFERRIN; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; LYMPHOCYTE ANTIGEN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; REACTIVE OXYGEN METABOLITE; SOLUBLE CD14 ANTIGEN; SURFACTANT PROTEIN A; SURFACTANT PROTEIN D; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; CATIONIC ANTIMICROBIAL PROTEIN 57, HUMAN; PLASMA PROTEIN;

EID: 79959775413     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc11-s238     Document Type: Review
Times cited : (22)

References (61)
  • 1
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • DOI 10.1038/nature05485, PII NATURE05485
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006;444:860-867 (Pubitemid 46024993)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 860-867
    • Hotamisligil, G.S.1
  • 2
    • 0037631831 scopus 로고    scopus 로고
    • Insulin resistance and chronic cardiovascular inflammatory syndrome
    • Fernández-Real JM, Ricart W. Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev 2003; 24:278-301 (Pubitemid 36724371)
    • (2003) Endocrine Reviews , vol.24 , Issue.3 , pp. 278-301
    • Fernandez-Real, J.M.1    Ricart, W.2
  • 3
    • 0348222671 scopus 로고    scopus 로고
    • Inflammation: The link between insulin resistance, obesity and diabetes
    • DOI 10.1016/j.it.2003.10.013
    • Dandona P, Aljada A, Bandyopadhyay A. Inflammation: the link between insulin resistance, obesity and diabetes. Trends Immunol 2004;25:4-7 (Pubitemid 38032801)
    • (2004) Trends in Immunology , vol.25 , Issue.1 , pp. 4-7
    • Dandona, P.1    Aljada, A.2    Bandyopadhyay, A.3
  • 4
    • 0031022434 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction
    • DOI 10.1074/jbc.272.2.971
    • Stephens JM, Lee J, Pilch PF. Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction. J Biol Chem 1997; 272:971-976 (Pubitemid 27034588)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.2 , pp. 971-976
    • Stephens, J.M.1    Lee, J.2    Pilch, P.F.3
  • 5
    • 0036894360 scopus 로고    scopus 로고
    • Interleukin-6 induces cellular insulin resistance in hepatocytes
    • Senn JJ, Klover PJ,Nowak IA,Mooney RA. Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes 2002;51: 3391-3399 (Pubitemid 35403441)
    • (2002) Diabetes , vol.51 , Issue.12 , pp. 3391-3399
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3    Mooney, R.A.4
  • 8
    • 33646543284 scopus 로고    scopus 로고
    • The modulation of inflammatory gene expression by lipids: Mediation through Toll-like receptors
    • Lee JY, Hwang DH. The modulation of inflammatory gene expression by lipids: mediation through Toll-like receptors. Mol Cells 2006;21:174-185
    • (2006) Mol Cells , vol.21 , pp. 174-185
    • Lee, J.Y.1    Hwang, D.H.2
  • 10
    • 1042280188 scopus 로고    scopus 로고
    • Association between Acute-Phase Reactants and Advanced Glycation End Products in Type 2 Diabetes
    • DOI 10.2337/diacare.27.1.223
    • Tan KC, Chow WS, Tam S, Bucala R, Betteridge J. Association between acutephase reactants and advanced glycation end products in type 2 diabetes. Diabetes Care 2004;27:223-228 (Pubitemid 38196736)
    • (2004) Diabetes Care , vol.27 , Issue.1 , pp. 223-228
    • Tan, K.C.B.1    Chow, W.-S.2    Tam, S.3    Bucala, R.4    Betteridge, J.5
  • 12
    • 2442421194 scopus 로고    scopus 로고
    • Is Oxidative Stress the Pathogenic Mechanism Underlying Insulin Resistance, Diabetes, and Cardiovascular Disease? The Common Soil Hypothesis Revisited
    • DOI 10.1161/01.ATV.0000122852.22604.78
    • Ceriello A, Motz E. Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited. Arterioscler Thromb Vasc Biol 2004;24: 816-823 (Pubitemid 38620857)
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , Issue.5 , pp. 816-823
    • Ceriello, A.1    Motz, E.2
  • 13
    • 0026782227 scopus 로고
    • Impaired immune responses in diabetes mellitus: Analysis of the factors and mechanisms involved. Relevance to the increased susceptibility of diabetic patients to specific infections
    • Moutschen MP, Scheen AJ, Lefebvre PJ. Impaired immune responses in diabetes mellitus: analysis of the factors and mechanisms involved. Relevance to the increased susceptibility of diabetic patients to specific infections. Diabete Metab 1992;18:187-201
    • (1992) Diabete Metab , vol.18 , pp. 187-201
    • Moutschen, M.P.1    Scheen, A.J.2    Lefebvre, P.J.3
  • 14
    • 35248894440 scopus 로고    scopus 로고
    • Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus
    • DOI 10.1016/j.clinbiochem.2007.07.016, PII S0009912007003025
    • Wang H,Meng QH, Gordon JR, Khandwala H, Wu L. Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus. Clin Biochem 2007;40:1232-1239 (Pubitemid 47562425)
    • (2007) Clinical Biochemistry , vol.40 , Issue.16-17 , pp. 1232-1239
    • Wang, H.1    Meng, Q.H.2    Gordon, J.R.3    Khandwala, H.4    Wu, L.5
  • 15
    • 33750846406 scopus 로고    scopus 로고
    • Neutrophils and monocytes as potentially important sources of proinflammatory cytokines in diabetes
    • DOI 10.1111/j.1365-2249.2006.03229.x
    • Hatanaka E, Monteagudo PT, Marrocos MS, Campa A. Neutrophils and monocytes as potentially important sources of proinflammatory cytokines in diabetes. Clin Exp Immunol 2006;146: 443-447 (Pubitemid 44722162)
    • (2006) Clinical and Experimental Immunology , vol.146 , Issue.3 , pp. 443-447
    • Hatanaka, E.1    Monteagudo, P.T.2    Marrocos, M.S.M.3    Campa, A.4
  • 16
    • 0035985095 scopus 로고    scopus 로고
    • Impaired neutrophil actin assembly causes persistent CD11b expression and reduced primary granule exocytosis in Type II diabetes
    • DOI 10.1007/s00125-002-0802-0
    • Advani A, Marshall SM, Thomas TH. Impaired neutrophil actin assembly causes persistent CD11b expression and reduced primary granule exocytosis in type II diabetes. Diabetologia 2002;45:719-727 (Pubitemid 34810697)
    • (2002) Diabetologia , vol.45 , Issue.5 , pp. 719-727
    • Advani, A.1    Marshall, S.M.2    Thomas, T.H.3
  • 17
    • 70349923422 scopus 로고    scopus 로고
    • Decreased circulating lactoferrin in insulin resistance and altered glucose tolerance as a possible marker of neutrophil dysfunction in type 2 diabetes
    • Moreno-Navarrete JM, Ortega FJ, Bassols J, Ricart W, Fernández- Real JM. Decreased circulating lactoferrin in insulin resistance and altered glucose tolerance as a possible marker of neutrophil dysfunction in type 2 diabetes. J Clin EndocrinolMetab 2009;94: 4036-4044
    • (2009) J Clin EndocrinolMetab , vol.94 , pp. 4036-4044
    • Moreno-Navarrete, J.M.1    Ortega, F.J.2    Bassols, J.3    Ricart, W.4    Fernández-Real, J.M.5
  • 18
    • 10044275561 scopus 로고    scopus 로고
    • In vivo evidences that insulin regulates human polymorphonuclear neutrophil functions
    • DOI 10.1189/jlb.0104050
    • Walrand S, Guillet C, Boirie Y, VassonMP. In vivo evidences that insulin regulates human polymorphonuclear neutrophil functions. J Leukoc Biol 2004;76:1104-1110 (Pubitemid 39602945)
    • (2004) Journal of Leukocyte Biology , vol.76 , Issue.6 , pp. 1104-1110
    • Walrand, S.1    Guillet, C.2    Boirie, Y.3    Vasson, M.-P.4
  • 19
    • 0035988194 scopus 로고    scopus 로고
    • High insulin exacerbates neutrophil-endothelial cell adhesion through endothelial surface expression of intercellular adhesion molecule-1 via activation of protein kinase c and mitogen-activated protein kinase
    • DOI 10.1007/s00125-001-0773-6
    • Okouchi M,OkayamaN, Shimizu M,OmiH, Fukutomi T, Itoh M. High insulin exacerbates neutrophil-endothelial cell adhesion through endothelial surface expression of intercellular adhesionmolecule- 1 via activation of protein kinase C and mitogen-activated protein kinase. Diabetologia 2002;45:556-559 (Pubitemid 34533835)
    • (2002) Diabetologia , vol.45 , Issue.4 , pp. 556-559
    • Okouchi, M.1    Okayama, N.2    Shimizu, M.3    Omi, H.4    Fukutomi, T.5    Itoh, M.6
  • 21
    • 33745789024 scopus 로고    scopus 로고
    • Insulin differentially regulates monocyte and polymorphonuclear neutrophil functions in healthy young and elderly humans
    • DOI 10.1210/jc.2005-1619
    • Walrand S, Guillet C, Boirie Y, VassonMP. Insulin differentially regulates monocyte and polymorphonuclear neutrophil functions in healthy young and elderly humans. J Clin Endocrinol Metab 2006;91:2738-2748 (Pubitemid 44024646)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.7 , pp. 2738-2748
    • Walrand, S.1    Guillet, C.2    Boirie, Y.3    Vasson, M.-P.4
  • 22
    • 47249138753 scopus 로고    scopus 로고
    • Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia
    • Stegenga ME, van der Crabben SN, Blümer RM, et al. Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia. Blood 2008;112:82-89
    • (2008) Blood , vol.112 , pp. 82-89
    • Stegenga, M.E.1    Van Der Crabben, S.N.2    Blümer, R.M.3
  • 23
    • 53149119231 scopus 로고    scopus 로고
    • Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding
    • Elgazar-Carmon V, Rudich A, Hadad N, Levy R. Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. J Lipid Res 2008;49: 1894-1903
    • (2008) J Lipid Res , vol.49 , pp. 1894-1903
    • Elgazar-Carmon, V.1    Rudich, A.2    Hadad, N.3    Levy, R.4
  • 24
    • 77249179661 scopus 로고    scopus 로고
    • Fat overload induces changes in circulating lactoferrin that are associated with postprandial lipemia and oxidative stress in severely obese subjects
    • Fernández-Real JM, García-Fuentes E, Moreno-Navarrete JM, et al. Fat overload induces changes in circulating lactoferrin that are associated with postprandial lipemia and oxidative stress in severely obese subjects. Obesity (Silver Spring) 2010;18:482-488
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 482-488
    • Fernández-Real, J.M.1    García-Fuentes, E.2    Moreno-Navarrete, J.M.3
  • 25
    • 70149108937 scopus 로고    scopus 로고
    • Effects of high-calcium diets with different whey proteins on weight loss and weight regain in high-fat-fed C57BL/6J mice
    • Pilvi TK, Harala S, Korpela R, Mervaala EM. Effects of high-calcium diets with different whey proteins on weight loss and weight regain in high-fat-fed C57BL/6J mice. Br J Nutr 2009;102:337-341
    • (2009) Br J Nutr , vol.102 , pp. 337-341
    • Pilvi, T.K.1    Harala, S.2    Korpela, R.3    Mervaala, E.M.4
  • 26
    • 28344440468 scopus 로고    scopus 로고
    • Molecular structure, binding properties and dynamics of lactoferrin
    • DOI 10.1007/s00018-005-5368-9
    • Baker EN, Baker HM. Molecular structure, binding properties and dynamics of lactoferrin. CellMol Life Sci 2005;62:2531-2539 (Pubitemid 41721228)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.22 , pp. 2531-2539
    • Baker, E.N.1    Baker, H.M.2
  • 27
    • 17744405513 scopus 로고    scopus 로고
    • Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-kappaB
    • DOI 10.1016/S0008-8749(03)00006-6
    • Håversen L, Ohlsson BG, Hahn-Zoric M, Hanson LA, Mattsby-Baltzer I. Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NFkappa B. Cell Immunol 2002;220:83-95 (Pubitemid 36349060)
    • (2002) Cellular Immunology , vol.220 , Issue.2 , pp. 83-95
    • Haversen, L.1    Ohlsson, B.G.2    Hahn-Zoric, M.3    Hanson, L.A.4    Mattsby-Baltzer, I.5
  • 28
    • 39749199066 scopus 로고    scopus 로고
    • Association of circulating lactoferrin concentration and 2 nonsynonymous LTF gene polymorphisms with dyslipidemia in men depends on glucose-tolerance status
    • DOI 10.1373/clinchem.2007.095943
    • Moreno-Navarrete JM, Ortega FJ, Bassols J, Castro A, Ricart W, Fernández-Real JM. Association of circulating lactoferrin concentration and 2 nonsynonymous LTF gene polymorphisms with dyslipidemia in men depends on glucose-tolerance status. Clin Chem 2008;54:301-309 (Pubitemid 351302631)
    • (2008) Clinical Chemistry , vol.54 , Issue.2 , pp. 301-309
    • Moreno-Navarrete, J.M.1    Ortega, F.J.2    Bassols, J.3    Castro, A.4    Ricart, W.5    Fernandez-Real, J.M.6
  • 29
    • 70349088147 scopus 로고    scopus 로고
    • Lactoferrin increases (172Thr)AMPK phosphorylation and insulin-induced (p473Ser)AKT while impairing adipocyte differentiation
    • Moreno-Navarrete JM, Ortega FJ, RicartW, Fernandez-Real JM. Lactoferrin increases (172Thr)AMPK phosphorylation and insulin-induced (p473Ser)AKT while impairing adipocyte differentiation. Int J Obes (Lond) 2009;33:991-1000
    • (2009) Int J Obes (Lond) , vol.33 , pp. 991-1000
    • Moreno-Navarrete, J.M.1    Ortega, F.J.2    Ricart, W.3    Fernandez-Real, J.M.4
  • 30
    • 0029005366 scopus 로고
    • Characterization of the structural elements in lipid A required for binding of a recombinant fragment of bactericidal/ permeability-increasing protein rBPI23
    • Gazzano-Santoro H, Parent JB, Conlon PJ, et al. Characterization of the structural elements in lipid A required for binding of a recombinant fragment of bactericidal/ permeability-increasing protein rBPI23. Infect Immun 1995;63:2201-2205
    • (1995) Infect Immun , vol.63 , pp. 2201-2205
    • Gazzano-Santoro, H.1    Parent, J.B.2    Conlon, P.J.3
  • 32
    • 33644757817 scopus 로고    scopus 로고
    • Natural antibiotics and insulin sensitivity: The role of bactericidal/permeability-increasing protein
    • DOI 10.2337/diabetes.55.1.216
    • Gubern C, López-Bermejo A, Biarnés J, Vendrell J, Ricart W, Fernández-Real JM. Natural antibiotics and insulin sensitivity: the role of bactericidal/permeabilityincreasing protein. Diabetes 2006;55: 216-224 (Pubitemid 43343318)
    • (2006) Diabetes , vol.55 , Issue.1 , pp. 216-224
    • Gubern, C.1    Lopez-Bermejo, A.2    Biarnes, J.3    Vendrell, J.4    Ricart, W.5    Fernandez-Real, J.M.6
  • 33
    • 77952084800 scopus 로고    scopus 로고
    • Circulating bactericidal/permeability-increasing protein (BPI) is associated with serum lipids and endothelial function
    • Esteve E, Castro A,Moreno JM, Vendrell J, Ricart W, Fernández-Real JM. Circulating bactericidal/permeability-increasing protein (BPI) is associated with serum lipids and endothelial function.ThrombHaemost 2010;103:780-787
    • (2010) ThrombHaemost , vol.103 , pp. 780-787
    • Esteve, E.1    Castro, A.2    Moreno, J.M.3    Vendrell, J.4    Ricart, W.5    Fernández-Real, J.M.6
  • 36
    • 0032769213 scopus 로고    scopus 로고
    • Anti-CD14 monoclonal antibodies inhibit the production of tumor necrosis factor alpha and interleukin-10 by human monocytes stimulated with killed and live Haemophilus influenzae or Streptococcus pneumoniae organisms
    • van Furth AM, Verhard-Seijmonsbergen EM, Langermans JA, van Dissel JT, van Furth R. Anti-CD14 monoclonal antibodies inhibit the production of tumor necrosis factor alpha and interleukin-10 by human monocytes stimulated with killed and live Haemophilus influenzae or Streptococcus pneumoniae organisms. Infect Immun 1999;67:3714-3718 (Pubitemid 29356982)
    • (1999) Infection and Immunity , vol.67 , Issue.8 , pp. 3714-3718
    • Van Furth, A.M.1    Verhard-Seijmonsbergen, E.M.2    Langermans, J.A.M.3    Van Dissel, J.T.4    Van Furth, R.5
  • 37
    • 0026518709 scopus 로고
    • Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein
    • Lee JD, Kato K, Tobias PS, Kirkland TN, Ulevitch RJ. Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein. J Exp Med 1992;175:1697-1705
    • (1992) J Exp Med , vol.175 , pp. 1697-1705
    • Lee, J.D.1    Kato, K.2    Tobias, P.S.3    Kirkland, T.N.4    Ulevitch, R.J.5
  • 38
    • 0025896328 scopus 로고
    • Shedding as a mechanism of down-modulation of CD14 on stimulated human monocytes
    • Bazil V, Strominger JL. Shedding as a mechanism of down-modulation of CD14 on stimulated human monocytes. J Immunol 1991;147:1567-1574
    • (1991) J Immunol , vol.147 , pp. 1567-1574
    • Bazil, V.1    Strominger, J.L.2
  • 39
    • 0028901991 scopus 로고
    • Increased circulating soluble CD14 is associated with high mortality in gramnegative septic shock
    • Landmann R, Zimmerli W, Sansano S, et al. Increased circulating soluble CD14 is associated with high mortality in gramnegative septic shock. J Infect Dis 1995; 171:639-644
    • (1995) J Infect Dis , vol.171 , pp. 639-644
    • Landmann, R.1    Zimmerli, W.2    Sansano, S.3
  • 40
    • 0028288011 scopus 로고
    • Recombinant soluble CD14 inhibits LPS-induced tumor necrosis factor-alpha production by cells in whole blood
    • Haziot A, Rong GW, Bazil V, Silver J, Goyert SM. Recombinant soluble CD14 inhibits LPS-induced tumor necrosis factor-alpha production by cells in whole blood. J Immunol 1994;152:5868-5876 (Pubitemid 24174167)
    • (1994) Journal of Immunology , vol.152 , Issue.12 , pp. 5868-5876
    • Haziot, A.1    Rong, G.-W.2    Bazil, V.3    Silver, J.4    Goyert, S.M.5
  • 41
    • 0029057595 scopus 로고
    • Recombinant soluble CD14 prevents mortality in mice treated with endotoxin (lipopolysaccharide)
    • Haziot A, Rong GW, Lin XY, Silver J, Goyert SM. Recombinant soluble CD14 prevents mortality in mice treated with endotoxin (lipopolysaccharide). J Immunol 1995;154:6529-6532
    • (1995) J Immunol , vol.154 , pp. 6529-6532
    • Haziot, A.1    Rong, G.W.2    Lin, X.Y.3    Silver, J.4    Goyert, S.M.5
  • 44
    • 0028935983 scopus 로고
    • Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein
    • Wurfel MM, Hailman E, Wright SD. Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein. J ExpMed 1995; 181:1743-1754
    • (1995) J ExpMed , vol.181 , pp. 1743-1754
    • Wurfel, M.M.1    Hailman, E.2    Wright, S.D.3
  • 46
    • 3242752008 scopus 로고    scopus 로고
    • Circulating soluble CD14 monocyte receptor is associated with increased alanine aminotransferase
    • DOI 10.1373/clinchem.2003.030015
    • Fernández-Real JM, López-Bermejo A, Broch M, Vendrell J, Richart C, Ricart W. Circulating soluble CD14 monocyte receptor is associated with increased alanine aminotransferase. Clin Chem 2004;50: 1456-1458 (Pubitemid 38970666)
    • (2004) Clinical Chemistry , vol.50 , Issue.8 , pp. 1456-1458
    • Fernandez-Real, J.M.1    Lopez-Bermejo, A.2    Broch, M.3    Vendrell, J.4    Richart, C.5    Ricart, W.6
  • 48
    • 0024316023 scopus 로고
    • Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein
    • Tobias PS, Soldau K, Ulevitch RJ. Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein. J Biol Chem 1989;264: 10867-10871 (Pubitemid 19161662)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.18 , pp. 10867-10871
    • Tobias, P.S.1    Soldau, K.2    Ulevitch, R.J.3
  • 50
    • 0027982115 scopus 로고
    • Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS
    • DOI 10.1084/jem.180.3.1025
    • Wurfel MM, Kunitake ST, Lichenstein H, Kane JP, Wright SD. Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J Exp Med 1994; 180:1025-1035 (Pubitemid 24256615)
    • (1994) Journal of Experimental Medicine , vol.180 , Issue.3 , pp. 1025-1035
    • Wurfel, M.M.1    Kunitake, S.T.2    Lichenstein, H.3    Kane, J.P.4    Wright, S.D.5
  • 52
    • 79551656875 scopus 로고    scopus 로고
    • A marker of endotoxemia is associated with obesity and related disorders in apparently healthy Chinese
    • Sun L, Yu Z, Ye X, et al. A marker of endotoxemia is associated with obesity and related disorders in apparently healthy Chinese. Diabetes Care 2010;33:1925-1932
    • (2010) Diabetes Care , vol.33 , pp. 1925-1932
    • Sun, L.1    Yu, Z.2    Ye, X.3
  • 55
    • 70349234521 scopus 로고    scopus 로고
    • Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans
    • Catalán V, Gómez-Ambrosi J, Rodríguez A, et al. Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans. J Mol Med 2009;87:803-813
    • (2009) J Mol Med , vol.87 , pp. 803-813
    • Catalán, V.1    Gómez-Ambrosi, J.2    Rodríguez, A.3
  • 56
    • 76749171211 scopus 로고    scopus 로고
    • Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in subjects with insulin resistance
    • Lond
    • Moreno-Navarrete JM, Manco M, Ibáñez J, et al. Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in subjects with insulin resistance. Int J Obes (Lond) 2010;34:240-249
    • (2010) Int J Obes , vol.34 , pp. 240-249
    • Moreno-Navarrete, J.M.1    Manco, M.2    Ibáñez, J.3
  • 57
    • 77951193688 scopus 로고    scopus 로고
    • Lipocalin-2 deficiency attenuates insulin resistance associated with ageing and obesity
    • Law IK, Xu A, Lam KS, et al. Lipocalin-2 deficiency attenuates insulin resistance associated with ageing and obesity. Diabetes 2010;12:872-882
    • (2010) Diabetes , vol.12 , pp. 872-882
    • Law, I.K.1    Xu, A.2    Lam, K.S.3
  • 59
    • 48649099066 scopus 로고    scopus 로고
    • Circulating surfactant protein A (SP-A), a marker of lung injury, is associated with insulin resistance
    • Fernández-Real JM, Chico B, Shiratori M, Nara Y, Takahashi H, RicartW. Circulating surfactant protein A (SP-A), a marker of lung injury, is associated with insulin resistance. Diabetes Care 2008;31:958-963
    • (2008) Diabetes Care , vol.31 , pp. 958-963
    • Fernández-Real, J.M.1    Chico, B.2    Shiratori, M.3    Nara, Y.4    Takahashi, H.5    Ricart, W.6
  • 60
    • 77953034083 scopus 로고    scopus 로고
    • Surfactant protein d, a marker of lung innate immunity, is positively associated with insulin sensitivity
    • Fernández-Real JM, Valdés S, Manco M, et al. Surfactant protein d, a marker of lung innate immunity, is positively associated with insulin sensitivity. Diabetes Care 2010;33:847-853
    • (2010) Diabetes Care , vol.33 , pp. 847-853
    • Fernández-Real, J.M.1    Valdés, S.2    Manco, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.