메뉴 건너뛰기




Volumn 6, Issue 7, 2011, Pages

The Drosophila Gap gene network is composed of two parallel toggle switches

Author keywords

[No Author keywords available]

Indexed keywords

ANTERIOR POSTERIOR AXIS; ARTICLE; BACTERIOPHAGE LAMBDA; CONTROLLED STUDY; DROSOPHILA; EMBRYO SEGMENTATION; GAP GENE; GENE; GENE REPRESSION; INSECT GENETICS; MUTANT; SIMULATION; ANIMAL; ANIMAL EMBRYO; BIOLOGICAL MODEL; DROSOPHILA MELANOGASTER; ENVIRONMENT; GENE REGULATORY NETWORK; GENE SILENCING; GENETICS; METABOLISM; MUTATION; PRENATAL DEVELOPMENT;

EID: 79959772412     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021145     Document Type: Article
Times cited : (45)

References (56)
  • 1
    • 0025328332 scopus 로고
    • A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Kruppel and knirps in the early Drosophila embryo
    • Hulskamp M, Pfeifle C, Tautz D, (1990) A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Kruppel and knirps in the early Drosophila embryo. Nature 346: 577-580.
    • (1990) Nature , vol.346 , pp. 577-580
    • Hulskamp, M.1    Pfeifle, C.2    Tautz, D.3
  • 2
    • 0025981573 scopus 로고
    • Mutually repressive interactions between the gap genes giant and Kruppel define middle body regions of the Drosophila embryo
    • Kraut R, Levine M, (1991) Mutually repressive interactions between the gap genes giant and Kruppel define middle body regions of the Drosophila embryo. Development 111: 611-621.
    • (1991) Development , vol.111 , pp. 611-621
    • Kraut, R.1    Levine, M.2
  • 3
    • 4644363054 scopus 로고    scopus 로고
    • Dynamical analysis of regulatory interactions in the gap gene system of Drosophila melanogaster
    • Jaeger J, Blagov M, Kosman D, Kozlov KN, Manu, et al. (2004) Dynamical analysis of regulatory interactions in the gap gene system of Drosophila melanogaster. Genetics 167: 1721-1737.
    • (2004) Genetics , vol.167 , pp. 1721-1737
    • Jaeger, J.1    Blagov, M.2    Kosman, D.3    Kozlov, K.N.4    Manu5
  • 4
    • 34249722123 scopus 로고    scopus 로고
    • Enhancer responses to similarly distributed antagonistic gradients in development
    • Epub 2007 Mar 2029
    • Zinzen RP, Papatsenko D, (2007) Enhancer responses to similarly distributed antagonistic gradients in development. PLoS Comput Biol 3: e84 Epub 2007 Mar 2029.
    • (2007) PLoS Comput Biol , vol.3
    • Zinzen, R.P.1    Papatsenko, D.2
  • 5
    • 42949151458 scopus 로고    scopus 로고
    • Dual regulation by the Hunchback gradient in the Drosophila embryo
    • Epub 2008 Feb 2919
    • Papatsenko D, Levine MS, (2008) Dual regulation by the Hunchback gradient in the Drosophila embryo. Proc Natl Acad Sci U S A 105: 2901-2906 Epub 2008 Feb 2919.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2901-2906
    • Papatsenko, D.1    Levine, M.S.2
  • 6
    • 3142734333 scopus 로고    scopus 로고
    • Dynamic control of positional information in the early Drosophila embryo
    • Jaeger J, Surkova S, Blagov M, Janssens H, Kosman D, et al. (2004) Dynamic control of positional information in the early Drosophila embryo. Nature 430: 368-371.
    • (2004) Nature , vol.430 , pp. 368-371
    • Jaeger, J.1    Surkova, S.2    Blagov, M.3    Janssens, H.4    Kosman, D.5
  • 7
    • 0026064083 scopus 로고
    • Activation and repression of transcription by the gap proteins hunchback and Kruppel in cultured Drosophila cells
    • Zuo P, Stanojevic D, Colgan J, Han K, Levine M, et al. (1991) Activation and repression of transcription by the gap proteins hunchback and Kruppel in cultured Drosophila cells. Genes Dev 5: 254-264.
    • (1991) Genes Dev , vol.5 , pp. 254-264
    • Zuo, P.1    Stanojevic, D.2    Colgan, J.3    Han, K.4    Levine, M.5
  • 8
    • 0028149131 scopus 로고
    • Autonomous concentration-dependent activation and repression of Kruppel by hunchback in the Drosophila embryo
    • Schulz C, Tautz D, (1994) Autonomous concentration-dependent activation and repression of Kruppel by hunchback in the Drosophila embryo. Development 120: 3043-3049.
    • (1994) Development , vol.120 , pp. 3043-3049
    • Schulz, C.1    Tautz, D.2
  • 9
    • 0024569785 scopus 로고
    • The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo
    • Driever W, Nusslein-Volhard C, (1989) The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo. Nature 337: 138-143.
    • (1989) Nature , vol.337 , pp. 138-143
    • Driever, W.1    Nusslein-Volhard, C.2
  • 10
    • 0024380401 scopus 로고
    • The gradient morphogen bicoid is a concentration-dependent transcriptional activator
    • Struhl G, Struhl K, Macdonald PM, (1989) The gradient morphogen bicoid is a concentration-dependent transcriptional activator. Cell 57: 1259-1273.
    • (1989) Cell , vol.57 , pp. 1259-1273
    • Struhl, G.1    Struhl, K.2    Macdonald, P.M.3
  • 12
    • 79952469264 scopus 로고    scopus 로고
    • Gene expression noise in spatial patterning: hunchback promoter structure affects noise amplitude and distribution in Drosophila Segmentation
    • Holloway DM, Lopes FJ, da Fontoura Costa L, Travencolo BA, Golyandina N, et al. (2011) Gene expression noise in spatial patterning: hunchback promoter structure affects noise amplitude and distribution in Drosophila Segmentation. PLoS Comput Biol 7: e1001069.
    • (2011) PLoS Comput Biol , vol.7
    • Holloway, D.M.1    Lopes, F.J.2    da Fontoura Costa, L.3    Travencolo, B.A.4    Golyandina, N.5
  • 13
    • 0029160137 scopus 로고
    • Posterior stripe expression of hunchback is driven from two promoters by a common enhancer element
    • Margolis JS, Borowsky ML, Steingrimsson E, Shim CW, Lengyel JA, et al. (1995) Posterior stripe expression of hunchback is driven from two promoters by a common enhancer element. Development 121: 3067-3077.
    • (1995) Development , vol.121 , pp. 3067-3077
    • Margolis, J.S.1    Borowsky, M.L.2    Steingrimsson, E.3    Shim, C.W.4    Lengyel, J.A.5
  • 14
    • 0025981572 scopus 로고
    • Spatial regulation of the gap gene giant during Drosophila development
    • Kraut R, Levine M, (1991) Spatial regulation of the gap gene giant during Drosophila development. Development 111: 601-609.
    • (1991) Development , vol.111 , pp. 601-609
    • Kraut, R.1    Levine, M.2
  • 15
  • 17
    • 84967592182 scopus 로고    scopus 로고
    • Computational Modeling of Gene Regulatory Networks - A Primer
    • London, Imperial College Press
    • Bolouri H, (2008) Computational Modeling of Gene Regulatory Networks- A Primer. London Imperial College Press.
    • (2008)
    • Bolouri, H.1
  • 18
    • 41949100688 scopus 로고    scopus 로고
    • Mutual interaction in network motifs robustly sharpens gene expression in developmental processes
    • Epub 2008 Feb 2007
    • Ishihara S, Shibata T, (2008) Mutual interaction in network motifs robustly sharpens gene expression in developmental processes. J Theor Biol 252: 131-144 Epub 2008 Feb 2007.
    • (2008) J Theor Biol , vol.252 , pp. 131-144
    • Ishihara, S.1    Shibata, T.2
  • 21
    • 0023679744 scopus 로고
    • The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner
    • Driever W, Nusslein-Volhard C, (1988) The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell 54: 95-104.
    • (1988) Cell , vol.54 , pp. 95-104
    • Driever, W.1    Nusslein-Volhard, C.2
  • 22
    • 0026532170 scopus 로고
    • Control of Drosophila body pattern by the hunchback morphogen gradient
    • Struhl G, Johnston P, Lawrence PA, (1992) Control of Drosophila body pattern by the hunchback morphogen gradient. Cell 69: 237-249.
    • (1992) Cell , vol.69 , pp. 237-249
    • Struhl, G.1    Johnston, P.2    Lawrence, P.A.3
  • 23
    • 33646901020 scopus 로고    scopus 로고
    • Reverse engineering the gap gene network of Drosophila melanogaster
    • Epub 2006 May 2019
    • Perkins TJ, Jaeger J, Reinitz J, Glass L, (2006) Reverse engineering the gap gene network of Drosophila melanogaster. PLoS Comput Biol 2: e51 Epub 2006 May 2019.
    • (2006) PLoS Comput Biol , vol.2
    • Perkins, T.J.1    Jaeger, J.2    Reinitz, J.3    Glass, L.4
  • 24
    • 65949084005 scopus 로고    scopus 로고
    • Canalization of gene expression in the Drosophila blastoderm by gap gene cross regulation
    • Epub 1002009 Mar 1000010
    • Manu, Surkova S, Spirov AV, Gursky VV, Janssens H, et al. (2009) Canalization of gene expression in the Drosophila blastoderm by gap gene cross regulation. PLoS Biol 7: e1000049 Epub 1002009 Mar 1000010.
    • (2009) PLoS Biol , vol.7
    • Manu1    Surkova, S.2    Spirov, A.V.3    Gursky, V.V.4    Janssens, H.5
  • 25
    • 77956287804 scopus 로고    scopus 로고
    • Software tool to model genetic regulatory networks Applications to the modeling of threshold phenomena and of spatial patterning in Drosophila
    • Dilao R, Muraro DA, software tool to model genetic regulatory networks Applications to the modeling of threshold phenomena and of spatial patterning in Drosophila. PLoS 5: e10743.
    • PLoS , vol.5
    • Dilao, R.1    Muraro, D.A.2
  • 26
    • 0001422329 scopus 로고
    • Quantitative model for gene regulation by lambda phage repressor
    • Ackers GK, Johnson AD, Shea MA, (1982) Quantitative model for gene regulation by lambda phage repressor. Proc Natl Acad Sci U S A 79: 1129-1133.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 1129-1133
    • Ackers, G.K.1    Johnson, A.D.2    Shea, M.A.3
  • 27
    • 20444382737 scopus 로고    scopus 로고
    • Regulation of transcription: from lambda to eukaryotes
    • Ptashne M, (2005) Regulation of transcription: from lambda to eukaryotes. Trends Biochem Sci 30: 275-279.
    • (2005) Trends Biochem Sci , vol.30 , pp. 275-279
    • Ptashne, M.1
  • 28
    • 24944522339 scopus 로고    scopus 로고
    • Bicoid cooperative DNA binding is critical for embryonic patterning in Drosophila
    • Epub 12005 Sep 13176
    • Lebrecht D, Foehr M, Smith E, Lopes FJ, Vanario-Alonso CE, et al. (2005) Bicoid cooperative DNA binding is critical for embryonic patterning in Drosophila. Proc Natl Acad Sci U S A 102: 13176-13181 Epub 12005 Sep 13176.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13176-13181
    • Lebrecht, D.1    Foehr, M.2    Smith, E.3    Lopes, F.J.4    Vanario-Alonso, C.E.5
  • 29
    • 0036901602 scopus 로고    scopus 로고
    • Modeling transcriptional regulatory networks
    • Bolouri H, Davidson EH, (2002) Modeling transcriptional regulatory networks. Bioessays 24: 1118-1129.
    • (2002) Bioessays , vol.24 , pp. 1118-1129
    • Bolouri, H.1    Davidson, E.H.2
  • 32
    • 33745658106 scopus 로고    scopus 로고
    • Computational Models for Neurogenic Gene Expression in the Drosophila Embryo
    • Zinzen RP, Senger K, Levine M, Papatsenko D, (2006) Computational Models for Neurogenic Gene Expression in the Drosophila Embryo. Curr Biol 16: 1358-1365.
    • (2006) Curr Biol , vol.16 , pp. 1358-1365
    • Zinzen, R.P.1    Senger, K.2    Levine, M.3    Papatsenko, D.4
  • 33
    • 78049325587 scopus 로고    scopus 로고
    • How long does it take to establish a morphogen gradient?
    • Berezhkovskii AM, Sample C, Shvartsman SY, (2010) How long does it take to establish a morphogen gradient? Biophys J 99: L59-61.
    • (2010) Biophys J , vol.99 , pp. 59-61
    • Berezhkovskii, A.M.1    Sample, C.2    Shvartsman, S.Y.3
  • 34
    • 77953401066 scopus 로고    scopus 로고
    • Multiscale modeling of diffusion in the early Drosophila embryo
    • Epub 12010 May 10017
    • Sample C, Shvartsman SY, (2010) Multiscale modeling of diffusion in the early Drosophila embryo. Proc Natl Acad Sci U S A 107: 10092-10096 Epub 12010 May 10017.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10092-10096
    • Sample, C.1    Shvartsman, S.Y.2
  • 35
    • 33749137281 scopus 로고    scopus 로고
    • Quantitative and predictive model of transcriptional control of the Drosophila melanogaster even skipped gene
    • Epub 2006 Sep 1117
    • Janssens H, Hou S, Jaeger J, Kim AR, Myasnikova E, et al. (2006) Quantitative and predictive model of transcriptional control of the Drosophila melanogaster even skipped gene. Nat Genet 38: 1159-1165 Epub 2006 Sep 1117.
    • (2006) Nat Genet , vol.38 , pp. 1159-1165
    • Janssens, H.1    Hou, S.2    Jaeger, J.3    Kim, A.R.4    Myasnikova, E.5
  • 37
    • 70549090448 scopus 로고    scopus 로고
    • Organization of developmental enhancers in the Drosophila embryo
    • Epub 2009 Aug 5663
    • Papatsenko D, Goltsev Y, Levine M, (2009) Organization of developmental enhancers in the Drosophila embryo. Nucleic Acids Res 37: 5665-5677 Epub 2009 Aug 5663.
    • (2009) Nucleic Acids Res , vol.37 , pp. 5665-5677
    • Papatsenko, D.1    Goltsev, Y.2    Levine, M.3
  • 38
    • 77956830473 scopus 로고    scopus 로고
    • Quantitative analysis of the Drosophila segmentation regulatory network using pattern generating potentials
    • Kazemian M, Blatti C, Richards A, McCutchan M, Wakabayashi-Ito N, et al. Quantitative analysis of the Drosophila segmentation regulatory network using pattern generating potentials. PLoS 8 (8): e1000456.
    • PLoS , vol.8 , Issue.8
    • Kazemian, M.1    Blatti, C.2    Richards, A.3    McCutchan, M.4    Wakabayashi-Ito, N.5
  • 39
    • 34447099234 scopus 로고    scopus 로고
    • Probing the limits to positional information
    • Gregor T, Tank DW, Wieschaus EF, Bialek W, (2007) Probing the limits to positional information. Cell 130: 153-164.
    • (2007) Cell , vol.130 , pp. 153-164
    • Gregor, T.1    Tank, D.W.2    Wieschaus, E.F.3    Bialek, W.4
  • 40
    • 58149187889 scopus 로고    scopus 로고
    • FlyEx, the quantitative atlas on segmentation gene expression at cellular resolution
    • Epub 2008 Oct 2025
    • Pisarev A, Poustelnikova E, Samsonova M, Reinitz J, (2009) FlyEx, the quantitative atlas on segmentation gene expression at cellular resolution. Nucleic Acids Res 37: D560-566 Epub 2008 Oct 2025.
    • (2009) Nucleic Acids Res , vol.37 , pp. 560-566
    • Pisarev, A.1    Poustelnikova, E.2    Samsonova, M.3    Reinitz, J.4
  • 42
    • 0027332476 scopus 로고
    • Cooperative dimerization of paired class homeo domains on DNA
    • Wilson D, Sheng G, Lecuit T, Dostatni N, Desplan C, (1993) Cooperative dimerization of paired class homeo domains on DNA. Genes Dev 7: 2120-2134.
    • (1993) Genes Dev , vol.7 , pp. 2120-2134
    • Wilson, D.1    Sheng, G.2    Lecuit, T.3    Dostatni, N.4    Desplan, C.5
  • 43
    • 0027998760 scopus 로고
    • Single-site mutations in the C-terminal domain of bacteriophage lambda cI repressor alter cooperative interactions between dimers adjacently bound to OR
    • Burz DS, Ackers GK, (1994) Single-site mutations in the C-terminal domain of bacteriophage lambda cI repressor alter cooperative interactions between dimers adjacently bound to OR. Biochemistry 33: 8406-8416.
    • (1994) Biochemistry , vol.33 , pp. 8406-8416
    • Burz, D.S.1    Ackers, G.K.2
  • 44
    • 0030478516 scopus 로고    scopus 로고
    • Expression and purification of the RNA polymerase III transcription specificity factor IIIB70 from Saccharomyces cerevisiae and its cooperative binding with TATA-binding protein
    • Librizzi MD, Moir RD, Brenowitz M, Willis IM, (1996) Expression and purification of the RNA polymerase III transcription specificity factor IIIB70 from Saccharomyces cerevisiae and its cooperative binding with TATA-binding protein. J Biol Chem 271: 32695-32701.
    • (1996) J Biol Chem , vol.271 , pp. 32695-32701
    • Librizzi, M.D.1    Moir, R.D.2    Brenowitz, M.3    Willis, I.M.4
  • 45
    • 0036080430 scopus 로고    scopus 로고
    • Do morphogen gradients arise by diffusion?
    • Lander AD, Nie Q, Wan FY, (2002) Do morphogen gradients arise by diffusion? Dev Cell 2: 785-796.
    • (2002) Dev Cell , vol.2 , pp. 785-796
    • Lander, A.D.1    Nie, Q.2    Wan, F.Y.3
  • 46
    • 34447104600 scopus 로고    scopus 로고
    • Stability and nuclear dynamics of the bicoid morphogen gradient
    • Gregor T, Wieschaus EF, McGregor AP, Bialek W, Tank DW, (2007) Stability and nuclear dynamics of the bicoid morphogen gradient. Cell 130: 141-152.
    • (2007) Cell , vol.130 , pp. 141-152
    • Gregor, T.1    Wieschaus, E.F.2    McGregor, A.P.3    Bialek, W.4    Tank, D.W.5
  • 47
    • 0032531831 scopus 로고    scopus 로고
    • Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo
    • Burz DS, Rivera-Pomar R, Jackle H, Hanes SD, (1998) Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo. Embo J 17: 5998-6009.
    • (1998) Embo J , vol.17 , pp. 5998-6009
    • Burz, D.S.1    Rivera-Pomar, R.2    Jackle, H.3    Hanes, S.D.4
  • 48
    • 32244435737 scopus 로고    scopus 로고
    • Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein
    • Ladame S, Schouten JA, Roldan J, Redman JE, Neidle S, et al. (2006) Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein. Biochemistry 45: 1393-1399.
    • (2006) Biochemistry , vol.45 , pp. 1393-1399
    • Ladame, S.1    Schouten, J.A.2    Roldan, J.3    Redman, J.E.4    Neidle, S.5
  • 49
    • 58149354385 scopus 로고    scopus 로고
    • Analysis of combinatorial cis-regulation in synthetic and genomic promoters
    • Epub 2008 Nov 2023
    • Gertz J, Siggia ED, Cohen BA, (2009) Analysis of combinatorial cis-regulation in synthetic and genomic promoters. Nature 457: 215-218 Epub 2008 Nov 2023.
    • (2009) Nature , vol.457 , pp. 215-218
    • Gertz, J.1    Siggia, E.D.2    Cohen, B.A.3
  • 50
    • 0029015420 scopus 로고
    • Activation of posterior gap gene expression in the Drosophila blastoderm
    • Rivera-Pomar R, Lu X, Perrimon N, Taubert H, Jackle H, (1995) Activation of posterior gap gene expression in the Drosophila blastoderm. Nature 376: 253-256.
    • (1995) Nature , vol.376 , pp. 253-256
    • Rivera-Pomar, R.1    Lu, X.2    Perrimon, N.3    Taubert, H.4    Jackle, H.5
  • 51
    • 0026355632 scopus 로고
    • Regulation of a segmentation stripe by overlapping activators and repressors in the Drosophila embryo
    • Stanojevic D, Small S, Levine M, (1991) Regulation of a segmentation stripe by overlapping activators and repressors in the Drosophila embryo. Science 254: 1385-1387.
    • (1991) Science , vol.254 , pp. 1385-1387
    • Stanojevic, D.1    Small, S.2    Levine, M.3
  • 52
    • 0028051349 scopus 로고
    • Positioning adjacent pair-rule stripes in the posterior Drosophila embryo
    • Langeland JA, Attai SF, Vorwerk K, Carroll SB, (1994) Positioning adjacent pair-rule stripes in the posterior Drosophila embryo. Development 120: 2945-2955.
    • (1994) Development , vol.120 , pp. 2945-2955
    • Langeland, J.A.1    Attai, S.F.2    Vorwerk, K.3    Carroll, S.B.4
  • 53
    • 70549113260 scopus 로고    scopus 로고
    • Stripe formation in the early fly embryo: principles, models, and networks
    • Papatsenko D, (2009) Stripe formation in the early fly embryo: principles, models, and networks. Bioessays 31: 1172-1180.
    • (2009) Bioessays , vol.31 , pp. 1172-1180
    • Papatsenko, D.1
  • 54
    • 0347987855 scopus 로고    scopus 로고
    • A self-organizing system of repressor gradients establishes segmental complexity in Drosophila
    • Clyde DE, Corado MS, Wu X, Pare A, Papatsenko D, et al. (2003) A self-organizing system of repressor gradients establishes segmental complexity in Drosophila. Nature 426: 849-853.
    • (2003) Nature , vol.426 , pp. 849-853
    • Clyde, D.E.1    Corado, M.S.2    Wu, X.3    Pare, A.4    Papatsenko, D.5
  • 55
    • 77956890234 scopus 로고
    • Monte Carlo Sampling Methods Using Markov Chains and Their Applications
    • Hastings WK, (1970) Monte Carlo Sampling Methods Using Markov Chains and Their Applications. Biometrika 57: 97-109.
    • (1970) Biometrika , vol.57 , pp. 97-109
    • Hastings, W.K.1
  • 56
    • 21144439341 scopus 로고    scopus 로고
    • A quasi-Monte Carlo Metropolis algorithm
    • Epub 2005 Jun 8813
    • Owen AB, Tribble SD, (2005) A quasi-Monte Carlo Metropolis algorithm. Proc Natl Acad Sci U S A 102: 8844-8849 Epub 2005 Jun 8813.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8844-8849
    • Owen, A.B.1    Tribble, S.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.