Carcinogenetic risk estimation based on quantification of DNA methylation levels in liver tissue at the precancerous stage

International Journal of Cancer

Volumn 129, Issue 5, 2011, Pages 1170-1179

  Nagashio, Ryo ^a   Arai, Eri ^a   Ojima, Hidenori ^a   Kosuge, Tomoo ^b   Kondo, Yutaka ^c   Kanai, Yae ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b NATIONAL CANCER CENTER HOSPITAL   (Japan)

^c AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

chronic hepatitis; hepatocellular carcinoma; liver cirrhosis; precancerous condition; pyrosequencing

Indexed keywords

ADULT; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA EXTRACTION; DNA METHYLATION; DNA MODIFICATION; FEMALE; GENE AMPLIFICATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIVER; LIVER CELL CARCINOMA; MALE; PRIORITY JOURNAL; PYROSEQUENCING; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; VALIDATION PROCESS;

AGED; CARCINOMA, HEPATOCELLULAR; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CPG ISLANDS; DNA METHYLATION; FEMALE; HUMANS; LIVER; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; PRECANCEROUS CONDITIONS; PROGNOSIS; RISK ASSESSMENT; SURVIVAL RATE;

EID: 79959756667     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26061     Document Type: Article

References (28)

1. Chang MH, Chen CJ, Lai MS, Hsu HM, Wu TC, Kong MS, Liang DC, Shau WY, Chen DS,. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. N Engl J Med 1997; 336: 1855-9.
2. Tanaka Y, Hanada K, Mizokami M, Yeo AE, Shih JW, Gojobori T, Alter HJ,. Inaugural article: a comparison of the molecular clock of hepatitis C virus in the United States and Japan predicts that hepatocellular carcinoma incidence in the United States will increase over the next two decades. Proc Natl Acad Sci USA 2002; 99: 15584-9. (Pubitemid 35403976)
3. Jones PA, Baylin SB,. The epigenomics of cancer. Cell 2007; 128: 683-92. (Pubitemid 46273572)
4. Sharma S, Kelly TK, Jones PA,. Epigenetics in Cancer. Carcinogenesis 2009; 31: 27-36.
5. Kanai Y, Hirohashi S,. Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state. Carcinogenesis 2007; 28: 2434-42. (Pubitemid 350238944)
6. Kanai Y,. Alterations of DNA methylation and clinicopathological diversity of human cancers. Pathol Int 2008; 58: 544-58.
7. Kanai Y, Ushijima S, Tsuda H, Sakamoto M, Sugimura T, Hirohashi S,. Aberrant DNA methylation on chromosome 16 is an early event in hepatocarcinogenesis. Jpn J Cancer Res 1996; 87: 1210-7.
8. Kondo Y, Kanai Y, Sakamoto M, Mizokami M, Ueda R, Hirohashi S,. Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis-a comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma. Hepatology 2000; 32: 970-9.
9. Kaneto H, Sasaki S, Yamamoto H, Itoh F, Toyota M, Suzuki H, Ozeki I, Iwata N, Ohmura T, Satoh T, Karino Y, Satoh T, et al. Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus. Gut 2001; 48: 372-7. (Pubitemid 32269566)
10. Saito Y, Kanai Y, Sakamoto M, Saito H, Ishii H, Hirohashi S,. Overexpression of a splice variant of DNA methyltransferase 3b. DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis. Proc Natl Acad Sci USA 2002; 99: 10060-5. (Pubitemid 34831172)
11. Saito Y, Kanai Y, Nakagawa T, Sakamoto M, Saito H, Ishii H, Hirohashi S,. Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas. Int J Cancer 2003; 105: 527-32. (Pubitemid 36578558)
12. Kanai Y,. Genome-wide DNA methylation profiles in precancerous conditions and cancers. Cancer Sci 2009; 101: 36-45.
13. Arai E, Kanai Y,. DNA methylation profiles in precancerous tissue and cancers: carcinogenetic risk estimation and prognostication based on DNA methylation status. Epigenomics 2010; 2: 467-81.
14. Misawa A, Inoue J, Sugino Y, Hosoi H, Sugimoto T, Hosoda F, Ohki M, Imoto I, Inazawa J,. Methylation-associated silencing of the nuclear receptor 1I2 gene in advanced-type neuroblastomas, identified by bacterial artificial chromosome array-based methylated CpG island amplification. Cancer Res 2005; 65: 10233-42. (Pubitemid 41743715)
15. Sugino Y, Misawa A, Inoue J, Kitagawa M, Hosoi H, Sugimoto T, Imoto I, Inazawa J,. Epigenetic silencing of prostaglandin E receptor 2 (PTGER2) is associated with progression of neuroblastomas. Oncogene 2007; 26: 7401-13. (Pubitemid 350158713)
16. Tanaka K, Imoto I, Inoue J, Kozaki K, Tsuda H, Shimada Y, Aiko S, Yoshizumi Y, Iwai T, Kawano T, Inazawa J,. Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma. Oncogene 2007; 26: 6456-68. (Pubitemid 47494215)
17. Arai E, Ushijima S, Fujimoto H, Hosoda F, Shibata T, Kondo T, Yokoi S, Imoto I, Inazawa J, Hirohashi S, Kanai Y,. Genome-wide DNA methylation profiles in both precancerous conditions and clear cell renal cell carcinomas are correlated with malignant potential and patient outcome. Carcinogenesis 2009; 30: 214-21.
18. Arai E, Ushijima S, Gotoh M, Ojima H, Kosuge T, Hosoda F, Shibata T, Kondo Y, Yokoi S, Imoto I, Inazawa J, Hirohashi S, et al. Genome-wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma. Int J Cancer 2009; 125: 2854-62.
19. Nishiyama N, Arai E, Chihara Y, Fujimoto H, Hosoda F, Shibata T, Kondo T, Tsukamoto T, Yokoi S, Imoto I, Inazawa J, Hirohashi S, et al. Genome-wide DNA methylation profiles in urothelial carcinomas and urothelia at the precancerous stage. Cancer Sci 2010; 101: 231-40.
20. Osoegawa K, Mammoser AG, Wu C, Frengen E, Zeng C, Catanese JJ, de Jong PJ,. A bacterial artificial chromosome library for sequencing the complete human genome. Genome Res 2001; 11: 483-96. (Pubitemid 32243858)
21. Clark SJ, Harrison J, Paul CL, Frommer M,. High sensitivity mapping of methylated cytosines. Nucleic Acids Res 1994; 22: 2990-7. (Pubitemid 24260626)
22. Shen L, Guo Y, Chen X, Ahmed S, Issa JP,. Optimizing annealing temperature overcomes bias in bisulfite PCR methylation analysis. Bio Techniques 2007; 42: 48-58.
23. Gao W, Kondo Y, Shen L, Shimizu Y, Sano T, Yamao K, Natsume A, Goto Y, Ito M, Murakami H, Osada H, Zhang J, et al. Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas. Carcinogenesis 2008; 29: 1901-10.
24. Baylin SB, Ohm JE,. Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006; 6: 107-16. (Pubitemid 43361543)
25. Estecio MR, Issa JP,. Tackling the methylome: recent methodological advances in genome-wide methylation profiling. Genome Med 2009; 1: 106.
26. Mohn F, Schubeler D,. Genetics and epigenetics: stability and plasticity during cellular differentiation. Trends Genet 2009; 25: 129-36.
27. Arase Y, Ikeda K, Suzuki F, Suzuki Y, Kobayashi M, Akuta N, Hosaka T, Sezaki H, Yatsuji H, Kawamura Y, Kobayashi M, Kumada H,. Comparison of interferon and lamivudine treatment in Japanese patients with HBeAg positive chronic hepatitis B. J Med Virol 2007; 79: 1286-92. (Pubitemid 47106264)
28. Yoshida H, Tateishi R, Arakawa Y, Sata M, Fujiyama S, Nishiguchi S, Ishibashi H, Yamada G, Yokosuka O, Shiratori Y, Omata M,. Benefit of interferon therapy in hepatocellular carcinoma prevention for individual patients with chronic hepatitis C. Gut 2004; 53: 425-30. (Pubitemid 38241342)