-
1
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones,P.A. et al. (2002) The fundamental role of epigenetic events in cancer. Nat. Rev. Genet., 3, 415-428.
-
(2002)
Nat. Rev. Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
-
2
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
Eden,A. et al. (2003) Chromosomal instability and tumors promoted by DNA hypomethylation. Science, 300, 455.
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
-
3
-
-
33644846509
-
Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
-
Baylin,S.B. et al. (2006) Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat. Rev. Cancer, 6, 107-116.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 107-116
-
-
Baylin, S.B.1
-
4
-
-
36549056015
-
Epigenetic changes in cancer
-
Gronbaek,K. et al. (2007) Epigenetic changes in cancer. APMIS 115, 1039-1159.
-
(2007)
APMIS
, vol.115
, pp. 1039-1159
-
-
Gronbaek, K.1
-
5
-
-
34249275353
-
Phenotypic plasticity and the epigenetics of human disease
-
Feinberg,A.P. (2007) Phenotypic plasticity and the epigenetics of human disease. Nature, 447, 433-440.
-
(2007)
Nature
, vol.447
, pp. 433-440
-
-
Feinberg, A.P.1
-
6
-
-
36949016699
-
Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state
-
Kanai,Y. et al. (2007) Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state. Carcinogenesis 28, 2434-2442.
-
(2007)
Carcinogenesis
, vol.28
, pp. 2434-2442
-
-
Kanai, Y.1
-
7
-
-
49749094793
-
Alterations of DNA methylation and clinicopathological diversity of human cancers
-
Kanai,Y. (2008) Alterations of DNA methylation and clinicopathological diversity of human cancers. Pathol. Int., 58, 544-558.
-
(2008)
Pathol. Int
, vol.58
, pp. 544-558
-
-
Kanai, Y.1
-
8
-
-
34948830291
-
High-throughput methylation profiling by MCA coupled to CpG island microarray
-
Estecio,M.R. et al. (2007) High-throughput methylation profiling by MCA coupled to CpG island microarray. Genome Res., 17, 1529-1536.
-
(2007)
Genome Res
, vol.17
, pp. 1529-1536
-
-
Estecio, M.R.1
-
9
-
-
37549066863
-
Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells
-
Jacinto,F.V. et al. (2007) Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells. Cancer Res., 67, 11481-11486.
-
(2007)
Cancer Res
, vol.67
, pp. 11481-11486
-
-
Jacinto, F.V.1
-
10
-
-
36549053021
-
Combining array-based approaches for the identification of candidate tumor suppressor loci in mature lymphoid neoplasms
-
Nielander,I. et al. (2007) Combining array-based approaches for the identification of candidate tumor suppressor loci in mature lymphoid neoplasms. APMIS, 115, 1107-1134.
-
(2007)
APMIS
, vol.115
, pp. 1107-1134
-
-
Nielander, I.1
-
11
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
Toyota,M. et al. (1999) CpG island methylator phenotype in colorectal cancer. Proc. Natl Acad. Sci. USA, 96, 8681-8686.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
-
12
-
-
33745213611
-
Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues
-
Arai,E. et al. (2006) Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues. Int. J. Cancer, 119, 288-296.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 288-296
-
-
Arai, E.1
-
13
-
-
28544444942
-
Methylation-associated silencing of the nuclear receptor 1I2 gene in advanced-type neuroblastomas, identified by bacterial artificial chromosome array-based methylated CpG island amplification
-
Misawa,A. et al. (2005) Methylation-associated silencing of the nuclear receptor 1I2 gene in advanced-type neuroblastomas, identified by bacterial artificial chromosome array-based methylated CpG island amplification. Cancer Res., 65, 10233-10242.
-
(2005)
Cancer Res
, vol.65
, pp. 10233-10242
-
-
Misawa, A.1
-
14
-
-
36349009317
-
Epigenetic silencing of prostaglandin E receptor 2 (PTGER2) is associated with progression of neuroblastomas
-
Sugino,Y. et al. (2007) Epigenetic silencing of prostaglandin E receptor 2 (PTGER2) is associated with progression of neuroblastomas. Oncogene, 26, 7401-7413.
-
(2007)
Oncogene
, vol.26
, pp. 7401-7413
-
-
Sugino, Y.1
-
15
-
-
34848924607
-
Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma
-
Tanaka,K. et al. (2007) Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma. Oncogene, 26, 6456-6468.
-
(2007)
Oncogene
, vol.26
, pp. 6456-6468
-
-
Tanaka, K.1
-
16
-
-
4143096081
-
Comparative genomic hybridization (CGH)-arrays pave the way for identification of novel cancer-related genes
-
Inazawa,J. et al. (2004) Comparative genomic hybridization (CGH)-arrays pave the way for identification of novel cancer-related genes. Cancer Sci., 95, 559-563.
-
(2004)
Cancer Sci
, vol.95
, pp. 559-563
-
-
Inazawa, J.1
-
18
-
-
0020376310
-
Prognostic significance of morphologic parameters in renal cell carcinoma
-
Fuhrman,S.A. et al. (1982) Prognostic significance of morphologic parameters in renal cell carcinoma. Am. J. Surg. Pathol., 6, 655-663.
-
(1982)
Am. J. Surg. Pathol
, vol.6
, pp. 655-663
-
-
Fuhrman, S.A.1
-
20
-
-
0023216973
-
Pathology of small hepatocellular carcinoma. A proposal for a new gross classification
-
Kanai,T. et al. (1987) Pathology of small hepatocellular carcinoma. A proposal for a new gross classification. Cancer, 60, 810-819.
-
(1987)
Cancer
, vol.60
, pp. 810-819
-
-
Kanai, T.1
-
21
-
-
38949212693
-
A novel CpG island set identifies tissue-specific methylation at developmental gene loci
-
Illingworth,R. et al. (2008) A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol. 6, e22.
-
(2008)
PLoS Biol
, vol.6
-
-
Illingworth, R.1
-
22
-
-
32944459562
-
High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk
-
Maekita,T. et al. (2006) High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin. Cancer Res., 12, 989-995.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 989-995
-
-
Maekita, T.1
-
23
-
-
33646369393
-
Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band
-
Frigola,J. et al. (2006) Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band. Nat. Genet., 38, 540-549.
-
(2006)
Nat. Genet
, vol.38
, pp. 540-549
-
-
Frigola, J.1
-
24
-
-
33749016030
-
Promoter hypermethylation profile of kidney cancer with new proapoptotic p53 target genes and clinical implications
-
Christoph,F. et al. (2006) Promoter hypermethylation profile of kidney cancer with new proapoptotic p53 target genes and clinical implications. Clin. Cancer Res., 12, 5040-5046.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 5040-5046
-
-
Christoph, F.1
-
25
-
-
33845778949
-
Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA
-
Urakami,S. et al. (2006) Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA. Clin. Cancer Res., 12, 6989-6997.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 6989-6997
-
-
Urakami, S.1
-
26
-
-
33744932953
-
Identification of novel target genes by an epigenetic reactivation screen of renal cancer
-
Ibanez de Caceres,I. et al. (2006) Identification of novel target genes by an epigenetic reactivation screen of renal cancer. Cancer Res., 66, 5021-5028.
-
(2006)
Cancer Res
, vol.66
, pp. 5021-5028
-
-
Ibanez de Caceres, I.1
-
27
-
-
34547779010
-
Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors
-
Costa,V.L. et al. (2007) Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors. BMC Cancer, 7, 133.
-
(2007)
BMC Cancer
, vol.7
, pp. 133
-
-
Costa, V.L.1
-
28
-
-
38549126847
-
Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma
-
Morris,M.R. et al. (2008) Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma. Br. J. Cancer, 98, 496-501.
-
(2008)
Br. J. Cancer
, vol.98
, pp. 496-501
-
-
Morris, M.R.1
-
29
-
-
53049094107
-
Genetic clustering of clear cell renal cell carcinoma based on array-CGH: Its association with DNA methylation alteration and patient outcome
-
Arai,E. et al. (2008) Genetic clustering of clear cell renal cell carcinoma based on array-CGH: Its association with DNA methylation alteration and patient outcome. Clin. Cancer Res., 14, 5531-5539.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 5531-5539
-
-
Arai, E.1
-
30
-
-
33846878502
-
Genomics of renal cell cancer: The biology behind and the therapy ahead
-
Jones,J. et al. (2007) Genomics of renal cell cancer: The biology behind and the therapy ahead. Clin. Cancer Res., 13, 685s-692s.
-
(2007)
Clin. Cancer Res
, vol.13
-
-
Jones, J.1
-
31
-
-
35748942010
-
Immunotherapy for metastatic renal cell carcinoma: Is it a therapeutic option yet?
-
vi149-52
-
Guida,M. et al. (2007) Immunotherapy for metastatic renal cell carcinoma: Is it a therapeutic option yet? Ann. Oncol., 18 (suppl. 6), vi149-52.
-
(2007)
Ann. Oncol
, vol.18
, Issue.SUPPL. 6
-
-
Guida, M.1
-
32
-
-
33846203776
-
Targeting von Hippel-Lindau pathway in renal cell carcinoma
-
Patel,P.H. et al. (2006) Targeting von Hippel-Lindau pathway in renal cell carcinoma. Clin. Cancer Res., 12, 7215-7520.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 7215-7520
-
-
Patel, P.H.1
-
33
-
-
0030476367
-
Aberrant DNA methylation on chromosome 16 is an early event in hepatocarcinogenesis
-
Kanai,Y. et al. (1996) Aberrant DNA methylation on chromosome 16 is an early event in hepatocarcinogenesis. Jpn. J. Cancer Res., 87, 1210-1217.
-
(1996)
Jpn. J. Cancer Res
, vol.87
, pp. 1210-1217
-
-
Kanai, Y.1
-
34
-
-
0030830914
-
DNA hypermethylation at the D17S5 locus in non-small cell lung cancers: Its association with smoking history
-
Eguchi,K. et al. (1997) DNA hypermethylation at the D17S5 locus in non-small cell lung cancers: Its association with smoking history. Cancer Res., 57, 4913-4915.
-
(1997)
Cancer Res
, vol.57
, pp. 4913-4915
-
-
Eguchi, K.1
-
35
-
-
33745627069
-
DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas
-
Peng,D.F. et al. (2006) DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas. Carcinogenesis, 27, 1160-1168.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1160-1168
-
-
Peng, D.F.1
|