-
1
-
-
0042266256
-
Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine
-
Babaei-Jadidi R, Karachalias N, Ahmed N, Battah S, Thornalley PJ. 2003. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes 52: 2110-2120.
-
(2003)
Diabetes
, vol.52
, pp. 2110-2120
-
-
Babaei-Jadidi, R.1
Karachalias, N.2
Ahmed, N.3
Battah, S.4
Thornalley, P.J.5
-
2
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee M. 2001. Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813-820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
3
-
-
0344837347
-
Benfotiamine blocks three major pathways of hypergly-cemic damage and prevents experimental diabetic reti-nopathy
-
Hammes H P, Du X, Edelstein D, Taguchi T, Matsumura T, Ju Q, Lin J, Bierhaus A, Nawroth P, Hannak D, Neu-maier M, Bergfeld R, Giardino I, Brownlee M. 2003. Benfotiamine blocks three major pathways of hypergly-cemic damage and prevents experimental diabetic reti-nopathy. Nat Med 9: 294-299.
-
(2003)
Nat Med
, vol.9
, pp. 294-299
-
-
Hammes, H.P.1
Du, X.2
Edelstein, D.3
Taguchi, T.4
Matsumura, T.5
Ju, Q.6
Lin, J.7
Bierhaus, A.8
Nawroth, P.9
Hannak, D.10
Neu-Maier, M.11
Bergfeld, R.12
Giardino, I.13
Brownlee, M.14
-
4
-
-
55949130943
-
Prevention of incipient diabetic cardiomyopathy by high-dose thiamine
-
Kohda Y, Shirakawa H, Yamane K, Otsuka K, Kono T, Terasaki F, Tanaka T. 2008. Prevention of incipient diabetic cardiomyopathy by high-dose thiamine. J Toxicol Sci 33: 459-472.
-
(2008)
J Toxicol Sci
, vol.33
, pp. 459-472
-
-
Kohda, Y.1
Shirakawa, H.2
Yamane, K.3
Otsuka, K.4
Kono, T.5
Terasaki, F.6
Tanaka, T.7
-
5
-
-
0037219409
-
Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?
-
Evans JL, Goldfine ID, Maddux BA, Grodsky GM. 2003. Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction? Diabetes 52: 1-8.
-
(2003)
Diabetes
, vol.52
, pp. 1-8
-
-
Evans, J.L.1
Goldfine, I.D.2
Maddux, B.A.3
Grodsky, G.M.4
-
6
-
-
18844395611
-
The pathogenesis of diabetic complications: The role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cyto-toxicity
-
Kiss L, Szabó C. 2005. The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cyto-toxicity. Mem Inst Oswaldo Cruz 100: 29-37.
-
(2005)
Mem Inst Oswaldo Cruz
, vol.100
, pp. 29-37
-
-
Kiss, L.1
Szabó, C.2
-
7
-
-
28844462418
-
Role of poly(ADP-ribose) poly-merase-1 activation in the pathogenesis of diabetic complications: Endothelial dysfunction, as a common underlying theme
-
Pacher P, Szabó C. 2005. Role of poly(ADP-ribose) poly-merase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme. Antioxid Redox Signal 7: 1568-1580.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1568-1580
-
-
Pacher, P.1
Szabó, C.2
-
8
-
-
19444377566
-
Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications
-
Szabó C. 2005. Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications. Pharmacol Res 52: 60-71.
-
(2005)
Pharmacol Res
, vol.52
, pp. 60-71
-
-
Szabó, C.1
-
9
-
-
33947320416
-
Discovery of a natural thia-mine adenine nucleotide
-
Bettendorff L, Wirtzfeld B, Makarchikov A, Mazzucchelli G, Frédérich M, Gigliobianco T, Gangolf M, De Pauw E, Angenot L, Wins P. 2007. Discovery of a natural thia-mine adenine nucleotide. Nat Chem Biol 3: 211-212.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 211-212
-
-
Bettendorff, L.1
Wirtzfeld, B.2
Makarchikov, A.3
Mazzucchelli, G.4
Frédérich, M.5
Gigliobianco, T.6
Gangolf, M.7
de Pauw, E.8
Angenot, L.9
Wins, P.10
-
10
-
-
66249102639
-
Thiaminylated adenine nucle-otides
-
Frédérich M, Delvaux D, Gigliobianco T, Gangolf M, Dive G, Mazzucchelli G, Elias B, De Pauw E, Angenot L, Wins P, Bettendorff L. 2009. Thiaminylated adenine nucle-otides. FEBS J 276: 3256-3268.
-
(2009)
FEBS J
, vol.276
, pp. 3256-3268
-
-
Frédérich, M.1
Delvaux, D.2
Gigliobianco, T.3
Gangolf, M.4
Dive, G.5
Mazzucchelli, G.6
Elias, B.7
de Pauw, E.8
Angenot, L.9
Wins, P.10
Bettendorff, L.11
-
11
-
-
0028025313
-
Thiamine in excitable tissues: Reflections on a non-cofactor role
-
Bettendorff L. 1994. Thiamine in excitable tissues: reflections on a non-cofactor role. Metab Brain Dis 9: 183-209.
-
(1994)
Metab Brain Dis
, vol.9
, pp. 183-209
-
-
Bettendorff, L.1
-
12
-
-
0035353080
-
Molecular mechanisms of thiamine utilization
-
Singleton CK, Martin PR. 2001. Molecular mechanisms of thiamine utilization. Curr Mol Med 1: 197-207.
-
(2001)
Curr Mol Med
, vol.1
, pp. 197-207
-
-
Singleton, C.K.1
Martin, P.R.2
-
13
-
-
55349116041
-
Metabolic and structural role of thiamine in nervous tissues
-
Bâ A. 2008. Metabolic and structural role of thiamine in nervous tissues. Cell Mol Neurobiol 28: 923-931.
-
(2008)
Cell Mol Neurobiol
, vol.28
, pp. 923-931
-
-
Bâ, A.1
-
14
-
-
65549167312
-
Thiamin diphosphate in biological chemistry: New aspects of thiamin metabolism, especially triphosphate derivatives acting other than as cofactors
-
Bettendorff L, Wins P. 2009. Thiamin diphosphate in biological chemistry: new aspects of thiamin metabolism, especially triphosphate derivatives acting other than as cofactors. FEBS J 276: 2917-2925.
-
(2009)
FEBS J
, vol.276
, pp. 2917-2925
-
-
Bettendorff, L.1
Wins, P.2
-
15
-
-
0032562650
-
The mechanism of the elongation and branching reaction of poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis
-
Ruf A, Rolli V, de Murcia G, Schulz GE. 1998. The mechanism of the elongation and branching reaction of poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis. J Mol Biol 278: 57-65.
-
(1998)
J Mol Biol
, vol.278
, pp. 57-65
-
-
Ruf, A.1
Rolli, V.2
de Murcia, G.3
Schulz, G.E.4
-
16
-
-
76749153013
-
Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888
-
Karlberg T, Hammarström M, Schütz P, Svensson L, Schüler H. 2010. Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888. Biochemistry 49: 1056-1058.
-
(2010)
Biochemistry
, vol.49
, pp. 1056-1058
-
-
Karlberg, T.1
Hammarström, M.2
Schütz, P.3
Svensson, L.4
Schüler, H.5
-
17
-
-
0037571112
-
Merck molecular force field. I-V
-
Halgren TA. 1996. Merck molecular force field. I-V. J Comput Chem 17: 490-641.
-
(1996)
J Comput Chem
, vol.17
, pp. 490-641
-
-
Halgren, T.A.1
-
18
-
-
33750587438
-
Molecular dynamics with coupling to an external bath
-
Berendsen HJC, Postma JPM, Van Gunsteren WF, DiNola A, Haak JR. 1984. Molecular dynamics with coupling to an external bath. J Chem Phys 81: 3684-3690.
-
(1984)
J Chem Phys
, vol.81
, pp. 3684-3690
-
-
Berendsen, H.J.C.1
Postma, J.P.M.2
van Gunsteren, W.F.3
Dinola, A.4
Haak, J.R.5
-
19
-
-
0001471515
-
The Nosé-Poincaré method for constant temperature molecular dynamics
-
Bond SD, Leimkuhler BJ, Laird BB. 1999. The Nosé-Poincaré method for constant temperature molecular dynamics. J Comp Phys 151: 114-134.
-
(1999)
J Comp Phys
, vol.151
, pp. 114-134
-
-
Bond, S.D.1
Leimkuhler, B.J.2
Laird, B.B.3
-
20
-
-
0032539957
-
+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling
-
+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling. Biochemistry 37: 3893-3900.
-
(1998)
Biochemistry
, vol.37
, pp. 3893-3900
-
-
Ruf, A.1
de Murcia, G.2
Schulz, G.E.3
-
21
-
-
33746064931
-
Binding mode of novel 1-substituted quinazoline derivatives to poly(ADP-ribose) polymerase-catalytic domain, revealed by X-ray crystal structure analysis of complexes
-
Matsumoto K, Kondo K, Ota T, Kawashima A, Kitamura K, Ishida T 2006. Binding mode of novel 1-substituted quinazoline derivatives to poly(ADP-ribose) polymerase-catalytic domain, revealed by X-ray crystal structure analysis of complexes. Biochim Biophys Acta 1764: 913-919.
-
(2006)
Biochim Biophys Acta
, vol.1764
, pp. 913-919
-
-
Matsumoto, K.1
Kondo, K.2
Ota, T.3
Kawashima, A.4
Kitamura, K.5
Ishida, T.6
-
22
-
-
67649983992
-
Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1)
-
Miyashiro J, Woods K W, Park CH, Liu X, Shi Y, Johnson EF, Bouska JJ, Olson AM. 2009. Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1). Bioorg Med Chem Lett 19: 4050-4054.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 4050-4054
-
-
Miyashiro, J.1
Woods, K.W.2
Park, C.H.3
Liu, X.4
Shi, Y.5
Johnson, E.F.6
Bouska, J.J.7
Olson, A.M.8
-
23
-
-
34548558863
-
Thia-mine diphosphate adenylyl transferase from E. coli: Functional characterization of the enzyme synthesizing adenosine thiamine triphosphate
-
Makarchikov AF, Brans A, Bettendorff L. 2007. Thia-mine diphosphate adenylyl transferase from E. coli: functional characterization of the enzyme synthesizing adenosine thiamine triphosphate. BMC Biochem 8: 17.
-
(2007)
BMC Biochem
, vol.8
, pp. 17
-
-
Makarchikov, A.F.1
Brans, A.2
Bettendorff, L.3
-
24
-
-
79952754268
-
Thiamine prevents obesity and obesity-associated metabolic disorders in OLETF rats
-
Tanaka T, Kono T, Terasaki F, Yasui K, Soyama A, Otsuka K, Fujita S, Yamane K, Manabe M, Usui K, Kohda Y. 2010. Thiamine prevents obesity and obesity-associated metabolic disorders in OLETF rats. J Nutr Sci Vitaminol 56: 335-346.
-
(2010)
J Nutr Sci Vitaminol
, vol.56
, pp. 335-346
-
-
Tanaka, T.1
Kono, T.2
Terasaki, F.3
Yasui, K.4
Soyama, A.5
Otsuka, K.6
Fujita, S.7
Yamane, K.8
Manabe, M.9
Usui, K.10
Kohda, Y.11
-
25
-
-
34248664706
-
Thiamine attenuates the hypertension and metabolic abnormalities in CD36-defective SHR: Uncoupling of glucose oxidation from cellular entry accompanied with enhanced protein O-GlcNAcylation in CD36 deficiency
-
Tanaka T, Sohmiya K, Kono T, Terasaki F, Horie R, Ohkaru Y, Muramatsu M, Takai S, Miyazaki M, Kitaura, Y. 2007. Thiamine attenuates the hypertension and metabolic abnormalities in CD36-defective SHR: uncoupling of glucose oxidation from cellular entry accompanied with enhanced protein O-GlcNAcylation in CD36 deficiency. Mol Cell Biochem 299: 23-35.
-
(2007)
Mol Cell Biochem
, vol.299
, pp. 23-35
-
-
Tanaka, T.1
Sohmiya, K.2
Kono, T.3
Terasaki, F.4
Horie, R.5
Ohkaru, Y.6
Muramatsu, M.7
Takai, S.8
Miyazaki, M.9
Kitaura, Y.10
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