Decameric GTP cyclohydrolase I forms complexes with two pentameric GTP cyclohydrolase I feedback regulatory proteins in the presence of phenylalanine or of a combination of tetrahydrobiopterin and GTP

Journal of Biological Chemistry

Volumn 273, Issue 32, 1998, Pages 20102-20108

  Yoneyama, Toshie ^a   Hatakeyama, Kazuyuki ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINO ACID; BIOPTERIN; GUANOSINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; PHENYLALANINE; REGULATOR PROTEIN; TETRAHYDROBIOPTERIN;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CROSS LINKING; CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDBACK SYSTEM; GEL FILTRATION; HYDROXYLATION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY; STOICHIOMETRY;

ANIMALS; BIOPTERIN; CHROMATOGRAPHY, GEL; CROSS-LINKING REAGENTS; DIMETHYL SUBERIMIDATE; GTP CYCLOHYDROLASE; GUANOSINE TRIPHOSPHATE; PHENYLALANINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; RATS; RECOMBINANT PROTEINS;

ANIMALIA;

EID: 0032493726     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.32.20102     Document Type: Article

References (18)

1. Harada, T., Kagamiyama, H., and Hatakeyama, K. (1993) Science 260, 1507-1510, and references therein
2. Nichol, C. H., Smith, G. K., and Duch, D. S. (1985) Annu. Rev. Biochem. 54, 729-764
3. Marietta, M. A. (1993) J. Biol. Chum. 268, 12231-12234
4. Kaufman, S. (1985) Biochem. Soc. Trans. 13, 433-436
5. Leeming, R. J., Blair, J. A., Green, A., and Raine, D. N. (1976) Arch. Dis. Child. 51, 771-777
6. Kaufman, S., Berlow, S., Summer, G. K., Milstien, S., Schulman, J. D., Orloff, S., Spielberg, S., and Pueschel, S. (1978) N. Engl. J. Med. 299, 673-679
7. Dhondt, J. L., Leroux, B., Farriaux, J. P., Largilliere, C., and Leeming, R. J. (1983) Eur. J. Pediatr. 141, 92-95
8. Hatakeyama, K., Harada, T., Suzuki, S., Watanabe, Y., and Kagamiyama, H. (1989) J. Biol. Chem. 264, 21660-21664
9. Hatakeyama, K., Inoue, Y., Harada, T., and Kagamiyama, H. (1991) J. Biol. Chem. 266, 765-769
10. Milstien, S., Jaffe, H., Kowlessur, D., and Bonner, T. I. (1996) J. Biol. Chem. 271, 19743-19751
11. Yoneyama, T., Brewer, J. M., and Hatakeyama, K. (1997) J. Biol. Chem. 272, 9690-9696
12. Benesadoun, A., and Weinstein, D. (1976) Anal. Biochem. 70, 241-250
13. Weber, K., and Osborn, M. (1975) in The Proteins (Neurath, H., and Hill, R. L., eds) pp. 179-223, Academic Press, New York
14. Hatakeyama, K., and Yoneyama, T. (1997) Methods Mol. Biol. 100, 267-274
15. Laemmli, U. K. (1970) Nature 227, 680-685
16. Newmann, U. (1996) in The Protein Protocols Handbook (Walker, J. M., ed) pp. 173-178, Humana Press Inc., Totowa, NJ
17. Nar, H., Huber, R., Meining, W., Schmid, C., Weinkauf, S., and Bacher, A. (1995) Structure 3, 459-466
18. Katzenmeier, G., Schmid, C., Kellermann, J., Lottspeich, F., and Bacher, A. (1991) Biol. Chem. Hoppe-Seyler 372, 991-997