Discovering new natural sweeteners

Optimising Sweet Taste in Foods

Volumn , Issue , 2006, Pages 292-306

  Kinghorn, A D ^a   Kim, N C ^b  

^a OHIO STATE UNIVERSITY   (United States)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79959734167     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1533/9781845691646.3.292     Document Type: Chapter

References (62)

1. Baek N.-I., Chung M.-S., Shamon L., Kardono L.B.S., Tsauri S., Padmawinata K., Pezzuto J.M., Soejarto D.D., Kinghorn A.D. Selligueain A, a novel highly sweet proanthocyanidin from the rhizomes of Selliguea feei. J Nat Prod 1993, 56:1532-1538.
2. Borrego F., Montijano H. Neohesperidin dihydrochalcone. Alternative Sweeteners 2001, 87-104. Marcel Dekker, New York, Revised and Expanded. Third Edition. L. O'Brien Nabors (Ed.).
3. Chen T.H., Chen S.C., Chan P., Chu Y.L., Yang H.Y., Cheng J.T. Mechanism of the hypoglycemic effect of stevioside, a glycoside of Stevia rebaudiana. Planta Med 2005, 71:108-113.
4. Choi Y.-H., Hussain R.A., Pezzuto J.M., Kinghorn A.D., Morton J.F. Abrusosides A-D, four novel sweet-tasting triterpene glycosides from the leaves of Abrus precatorius. J Nat Prod 1989, 52:1118-1127.
5. Choi Y.-H., Kinghorn A.D., Shi Z., Zhang H., Teo B.K. Abrusoside A: a new type of highly sweet triterpene glycoside. J Chem Soc, Chem Commun 1989, 887-888.
6. Chung M.-S., Kim N.-C., Long L., Shamon L., Ahmad W.-Y., Sagrero-Nieves L., Kardono L.B.S., Kennelly E.J., Pezzuto J.M., Soejarto D.D., Kinghorn A.D. Dereplication of saccharide and polyol constituents of candidate sweet-tasting plants: isolation of the sesquiterpene glycoside mukurozioside IIb as a sweet principle of Sapindus rarak. Phytochem Anal 1997, 8:49-54.
7. Dalton L. Licorice root is used worldwide as a flavor and a medicine. Chem Eng News 2002, 37. (August 12).
8. De Klerk G.J., Nieuwenhuis M.G., Beutler J.J. Lesson of the week: hypokal-aemia and hypertension associated with use of liquorice flavoured chewing gum. BMJ 1997, 314:731-732.
9. Dubois G.E., Bunes L.A., Dietrich P.S., Stephenson R.A. Diterpenoid sweeteners. Synthesis and sensory evaluation of biologically stable analogues of stevioside. J Agric Food Chem 1984, 32:1321-1325.
10. Duffy V.B., Sigman-Grant M., Powers M.A., Elmore D., Myers E.F., Quagliani D., Spano M., Stitzel K.F., Taylor S., Earl R., Connor S. Position of the American Dietetic Association: use of nutritive and nonnutritive sweeteners. J Am Diet Assoc 2004, 104:255-275.
11. Esaki S., Tanaka R., Kamiya S. Synthesis and taste of certain steviol glycosides. Agric Biol Chem 1984, 48:1831-1834.
12. Fischer C.M., Harper H.J., Henry J.R.W.J., Mohlenkamp J.R.M.K., Romer K., Swaine J.R.R.L. Beverage Compositions and Sweetening Compositions which Contain Juice Derived from Botanical Subfamily Cucurbitaceae 1994, The Procter & Gamble Company, United States.
13. Fukunaga Y., Miyata T., Nakayasu N., Mizutani K., Kasai R., Tanaka O. Enzymatic transglucosylation products of stevioside: separation and sweetness evaluation. Agric Biol Chem 1989, 53:1603-1607.
14. Greaves T. Intellectual Property Right for Indigenous Peoples: A Sourcebook 1994, Society for Applied Anthropology, Oklahoma City, Oklahoma.
15. Huan V.D., Ohtani K., Kasai R., Yamasaki K., Tuu N.V. Sweet pregnane glycosides from Telosma procumbens. Chem Pharm Bull 2001, 49:453-460.
16. Hussain R.A., Kinghorn A.D., Soejarto D.D. Sweetening agents of plant origin: literature search for candidate sweet plants. Econ Bot 1988, 42:267-283.
17. Hussain R.A., Lin Y.-M., Poveda L.J., Bordas E., Chung B.S., Pezzuto J.M., Soejarto D.D., Kinghorn A.D. Plant-derived sweetening agents: saccharide and polyol constituents of some sweet-tasting plants. J Ethnopharmacol 1990, 28:103-115.
18. Hussain R.A., Poveda L.J., Pezzuto J.M., Soejarto D.D., Kinghorn A.D. Sweetening agents of plant origin: phenylpropanoid constituents of seven sweet-tasting plants. Econ Bot 1990, 44:174-182.
19. Ishikawa H., Kitahata S., Ohtani K., Ikuhara C., Tanaka O. Production of stevioside and rubusoside derivatives by transfructosylation of β-fructo-furanosidase. Agric Biol Chem 1990, 54:3137-3143.
20. Kamiya S., Konishi F., Esaki S. Synthesis and taste of some analogs of stevioside. Agric Biol Chem 1979, 43:3553-3557.
21. Kaneda N., Kasai R., Yamasaki K., Tanaka O. Chemical studies on sweet diterpene-glycosides of Stevia rebaudiana: conversion of stevioside into rebaudioside A. Chem Pharm Bull 1977, 25:2466-2467.
22. Kennelly E.J., Cai L., Long L., Shamon L., Zaw K., Zhou B.-N., Pezzuto J.M., Kinghorn A.D. Novel highly sweet secodammarane glycosides from Pterocarya paliurus. J Agric Food Chem 1995, 43:2602-2607.
23. Kim J., Pezzuto J.M., Soejarto D.D., Lang F.A., Kinghorn A.D. Polypodoside A, an intensely sweet constituent of the rhizomes of Polypodium glycyrrhiza. J Nat Prod 1988, 51:1166-1172.
24. Kim N.-C., Kinghorn A.D. Sweet-tasting and sweetness-modifying constituents of plants. Studies in Natural Products Chemistry Vol 27 Bioactive Natural Products Part H 2002, 3-57. Elsevier Scientific Publishers, Amsterdam. Atta-ur-Rahman (Ed.).
25. Kim N.-C., Kinghorn A.D. Highly sweet compounds of plant origin. Arch Pharm Res 2002, 25:725-746.
26. Kim S.-H., Kang C.-H., Cho J.-M. Sweet Proteins. Sweeteners, Discovery, Molecular Design, and Chemoreception 1991, 28-40. American Chemical Society, Washington DC. D.E. Walters, F.T. Orthoefer, G.E. DuBois (Eds.).
27. Kinghorn A.D. Overview. Stevia: the Genus Stevia 2002, 1-17. Taylor & Francis, London. A.D. Kinghorn (Ed.).
28. Kinghorn A.D., Compadre C.M. Less common high-potency sweeteners. Alternative Sweeteners 2001, 209-233. Marcel Dekker, New York, Revised and Expanded. Third Edition. L. O'Brien Nabors (Ed.).
29. Kinghorn A.D., Kennelly E.J. Discovery of highly sweet compounds from natural sources. J Chem Educ 1995, 72:676-680.
30. Kinghorn A.D., Soejarto D.D. Sweetening agents of plant origin. CRC Crit Rev Plant Sci 1986, 4:79-120.
31. Kinghorn A.D., Soejarto D.D. Intensely sweet compounds of natural origin. Med Res Rev 1989, 9:91-115.
32. Kinghorn A.D., Soejarto D.D. Discovery of terpenoid and phenolic sweeteners from plants. Pure Appl Chem 2002, 74:1169-1179.
33. Kinghorn A.D., Fullas F., Hussain R.A. Structure-activity relationships of highly sweet natural products. Attar-ur-Rahman, Studies in Natural Product Chemistry Vol. 15, Structure and Chemistry (Part C) 1995, 3-41. Elsevier Science Publishers, Amsterdam.
34. Kinghorn A.D., Wu C.D., Soejarto D.D. Stevioside. Alternative Sweeteners 2001, 167-183. Marcel Dekker, New York, Revised and Expanded. Third Edition. L. O'Brien Nabors (Ed.).
35. Kitagawa I. Licorice root. A natural sweetener and an important ingredient in Chinese medicine. Pure Appl Chem 2002, 74:1189-1198.
36. Kohda H., Kasai R., Yamasaki K., Murakami K., Tanaka O. New sweet diterpene glycosides from Stevia rebaudiana. Phytochemistry 1976, 15:981-983.
37. Kohmura M., Mizukoshi T., Nio N., Suzuki E.-I., Ariyoshi Y. Structure-taste relationships of the sweet protein monellin. Pure Appl Chem 2002, 74:1235-1242.
38. Konoshima T., Takasaki M. Cancer-chemopreventive effects of natural sweeteners and related compounds. Pure Appl Chem 2002, 74:1309-1316.
39. Kurihara Y. Characterization of antisweet substance, sweet proteins, and sweetness-inducing proteins. Crit Rev Food Sci Nutr 1992, 32:231-252.
40. Li X., Staszewski L., Xu H., Durick K., Zoller M., Adler E. Human receptors for sweet and umami taste. Proc Natl Acad Sci USA 2002, 99:4692-4696.
41. Marris E. More flavour up front. Nature 2005, 435:559.
42. Masuda H., Ohtani K., Mizutani K., Ogawa S., Kasai R., Tanaka O. Chemical study on Haematoxylon campechianum: a sweet principle and new dibenz[b, d]-oxocin derivatives. Chem Pharm Bull 1991, 39:1382-1384.
43. Ming D., Hellekant G. Brazzein, a new high-potency thermostable sweet protein from Pentadiplandra brazzeana B. FEBS Lett 1994, 355:106-108.
44. Mizutani K., Tanaka O. Use of Stevia rebaudiana sweeteners in Japan. Stevia: the Genus Stevia 2002, 178-195. Taylor & Francis, London. A.D. Kinghorn (Ed.).
45. Mizutani K., Miyata T., Kasai R., Tanaka O., Ogawa S., Doi S. Study on improvement of sweeteners of steviol bisglycosides: selective enzymatic transglucosylation of the 13-O-glycosyl moiety. Agric Biol Chem 1989, 53:395-398.
46. Mizutani K., Kuramoto T., Tamura Y., Ohtake N., Doi S., Nakamura M., Tanaka O. Sweetness of glycyrrhetic acid 3-Oβ-d-monoglucuronide and the related glycosides. Biosci Biotechnol Biochem 1994, 58:554-555.
47. Mizutani K., Kambara T., Masuda H., Tamura Y., Ikeda T., Tanaka O., Tokuda H., Nishino H., Kozuka M., Konoshima T., Takasaki M. Glycyrrhetic acid monoglucuronide (MGGR): biological activities. Toward Natural Medicine Research in the 21st Century 1998, 225-235. Elsevier, Amsterdam. H. Ageta, N. Aimi, Y. Ebizuka, T. Fujita, G. Honda (Eds.).
48. Nelson G., Hoon M.A., Chandrashekar J., Zhang Y., Ryba N.J.P., Zuker C.S. Mammalian sweet taste receptors. Cell 2001, 106:381-390.
49. Nishizawa M., Yamada H. Intensely sweet saponin osladin: synthetic and structural study. Adv Exp Med Biol 1996, 405:25-36.
50. Ohtani K., Yamasaki K. Methods to improve the taste of the sweet principles of Stevia rebaudiana. Stevia: the Genus Stevia 2002, 138-159. Taylor & Francis, London. A.D. Kinghorn (Ed.).
51. Shibasato M. Current status of Stevia sweeteners and its application. Japan Food Sci 1995, 51-58.
52. Soejarto D.D., Kinghorn A.D., Farnsworth N.R. Potential sweetening agents of plant origin. III. Organoleptic evaluation of Stevia leaf herbarium samples for sweeteners. J Nat Prod 1982, 45:590-599.
53. Soejarto D.D., Compadre C.M., Medon P.J., Kamath S.K., Kinghorn A.D. Potential sweetening agents of plant origin. II. Field search for sweet tasting Stevia species. Econ Bot 1983, 37:71-75.
54. Suttisri R., Lee I.-S., Kinghorn A.D. Plant-derived triterpenoid sweetness inhibitors. J Ethnopharmacol 1995, 47:9-26.
55. Suzuki Y.A., Murata Y., Inui H., Sugiura M., Nakano Y. Triterpene glycosides of Siraitia grosvenori inhibit rat intestinal maltase and suppress the rise in blood glucose level after a single oral administration of maltose in rats. J Agric Food Chem 2005, 53:2941-2946.
56. Takemoto T., Arihara S., Nakajima T., Okuhira M. Studies on the constituents of Fructus Momordicae. I. On the sweet principle. Yakugaku Zasshi 1983, 103:1151-1154.
57. Tanaka O. Improvement of taste of natural sweeteners. Pure Appl Chem 1997, 69:675-683.
58. van der Wel H. Isolation and characterization of the sweet principles from Dioscoreophyllum cumminsii. FEBS Lett 1972, 21:88-90.
59. van Rossum T.G.J., De Jong F.H., Hop W.C.J., Boomsma F., Schalm S.W. "Pseudoaldosteronism" induced by intravenous glycyrrhizin treatment of chronic hepatitis C patients. Neth J Gastroenterol Hepatol 2001, 16:789-795.
60. Vleggaar R., Ackerman L.G.J., Steyn P.S. Structure elucidation of monatin, a high-intensity sweetener isolated from the plant Schlerochiton ilicifolius. J Chem Soc, Perkin Trans 1992, 1:3095-3098.
61. Yang D.J., Zhong Z.C., Xie Z.M. Studies on the sweet principles from the leaves of Cyclocarya paliurus (Batal.) Iljinskaya. Yao Hsueh Hsueh Pao 1992, 27:841-844.
62. Yoshikawa M., Morikawa T., Nakano K., Pongpiriyadacha Y., Murakami T., Matsuda H. Characterization of new sweet triterpene saponins from Albizia myriophylla. J Nat Prod 2002, 65:1638-1642.