TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections

European Journal of Immunology

Volumn 41, Issue 7, 2011, Pages 1948-1957

  Hansen, Ann K ^a   Regner, Matthias ^b   Bonefeld, Charlotte M ^a   Boding, Lasse ^a   Kongsbak, Martin ^a   Ødum, Niels ^a,c   Müllbacher, Arno ^b   Geisler, Carsten ^a   von Essen, Marina R ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Australian National University   (Australia)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

C Cbl; Cytotoxicity; T cells; TCR down regulation; Virus

Indexed keywords

GRANZYME B; T LYMPHOCYTE RECEPTOR; TYROSINE; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE C CB1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ECTROMELIA VIRUS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXOCYTOSIS; INFECTION PREVENTION; INFECTION SENSITIVITY; MORTALITY; MOUSE; MOUSEPOX; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD3; ANTIGENS, CD44; BLOTTING, WESTERN; CELL LINE; CYTOTOXICITY, IMMUNOLOGIC; ECTROMELIA VIRUS; ECTROMELIA, INFECTIOUS; EXOCYTOSIS; GRANZYMES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PERFORIN; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-CBL; RECEPTORS, ANTIGEN, T-CELL; RNA INTERFERENCE; RNA, SMALL INTERFERING; T-LYMPHOCYTES, CYTOTOXIC; UBIQUITIN-PROTEIN LIGASES;

EID: 79959702357     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141413     Document Type: Article

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