Evolution of β-lactams resistance in Gram-negative bacteria in Tunisia

Critical Reviews in Microbiology

Volumn 37, Issue 3, 2011, Pages 167-177

  Chouchani, Chedly ^a   Marrakchi, Rim ^a,b   El Salabi, Allaaeddin ^c  

^a UNIVERSITY OF CARTHAGE   (Tunisia)

^b FACULTÉ DES SCIENCES DE TUNIS   (Tunisia)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Antibiotic resistance; Tunisia; lactamases

Indexed keywords

BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CARBAPENEM; CEFOXITIN; CEFTAZIDIME; CEPHALOSPORIN; CEPHALOSPORINASE; ERTAPENEM; IMIPENEM; MEROPENEM; PENICILLIN G;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; CITROBACTER FREUNDII; ENTEROBACTERIACEAE; ESCHERICHIA COLI; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GRAM NEGATIVE BACTERIUM; KLEBSIELLA PNEUMONIAE; NONHUMAN; PRIORITY JOURNAL; PROTEUS MIRABILIS; PSEUDOMONAS AERUGINOSA; REVIEW; SALMONELLA; TUNISIA;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; NEGIBACTERIA;

EID: 79959700071     PISSN: 1040841X     EISSN: 15497828     Source Type: Journal    
DOI: 10.3109/1040841X.2011.552880     Document Type: Review

References (76)

1. Abbassi M S, Torres C, Achour W, Vinué L, Sáenz Y, Costa D, Bouchami O, Ben Hassen A. (2008). Genetic characterization of CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli strains isolated from stem cell transplant patients in Tunisia. Inter. J. of Antimicrob. Agents, 32, 308-314.
2. Aubert D, Naas T, Héritier C, Poirel L, Nordmann P. (2006). Functional characterization of IS1999, an IS4 family element involved in mobilization and expression of β-lactam resistance genes. J Bacteriol, 188, 6506-6514. (Pubitemid 44412060)
3. Barlow M, Reik RA, Jacobs SD, Medina M, Meyer MP, McGowan JE, Tenover FC. (2008). High Rate of Mobilization for blaCTX-Ms. Emerg Infect Dis, 14, 423-428.
4. Ben Achour N, Mercuri PS, Ben Moussa M, Galleni M, Belhadj O. (2009a). Characterization of a novel extended-spectrum TEM-type beta-lactamase, TEM-164, in a clinical strain of Klebsiella pneumoniae in Tunisia. Microb Drug Resist, 15, 195-199.
5. Ben Achour N, Mercuri PS, Power P, Belhadj C, Ben Moussa M, Galleni M, Belhadj O. (2009b). First detection of CTX-M-28 in a Tunisian hospital from a cefotaxime resistant Klebsiella pneumoniae strain. Path. Biol, 57, 343-348.
6. Ben Hassen A, Meddeb M, Ben Chaabane T, Zribi M, Ben Redjeb S. (1994). Characteristics of the antibiotic resistance plasmid in Salmonella typhi isolated in Tunis in 1990. Ann Biol Clin (Paris), 52, 133-136. (Pubitemid 24133415)
7. Ben Redjeb S, Ben Hassen A, Verdet C, Arlet G, Bouabdallah F, Philippon A. (1999). β-lactamase plasmidique (AmpC) chez un Proteus mirabilis en Tunisie. Med Mal Infect, 29, 415-417. (Pubitemid 29498118)
8. Ben Slama K, Jouini A, Ben Sallem R, Somalo S, Sáenz Y, Estepa V, Boudabous A, Torres C. (2010). Prevalence of broad-spectrum cephalosporin- resistant Escherichia coli isolates in food samples in Tunisia, and characterization of integrons and antimicrobial resistance mechanisms implicated. Inter J Food Microbiol, 137: 281-286
9. Ben-Hamouda T, Foulon T, Ben-Mahrez K. (2004). Involvement of SHV-12 and SHV-2a encoding plasmids in outbreaks of extended-spectrum beta-lactamase- producing Klebsiella pneumoniae in a Tunisian neonatal ward. Microb Drug Resist, 10, 132-138. (Pubitemid 38879013)
10. Bethel CR, Distler AM, Ruszczycky MW, Carey MP, Carey PR, Hujer AM, Taracila M, Helfand MS, Tomson JM, Kalp M, Anderson VE, Leonard DA, Hujer KM, Abe T, Venkatesan AM, Mansour TS, Bonomo RA. (2008). Inhibition of OXA-1 β-lactamase by penems. Antimicrob Agents Chemother, 52, 3135 3143.
11. Bidet P, Burghofer B, Gautier V, Brahimi N, Mariani-Kurkdjian P, El-Ghoneimi A, Bingen E, Arlet G. (2005). In vivo transfer of plasmid encoded ACC-1 AmpC from Klebsiella pneumoniae to Escherichia coli in an infant and selection of impermeability to imipenem in K. pneumoniae. Antimicrob Agents Chemother, 49, 3562-3565. (Pubitemid 41060620)
12. Bonnet R. (2004). Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes. Antimicrob Agents Chemother, 48, 1-14. (Pubitemid 38040170)
13. Bouallegue OG, Ben Salem Y, Fabre L, Demartin M, Grimont PAD, Mzoughi R, Weill FX. (2005). Nosocomial outbreak caused by Salmonella enterica serotype Livingstone producing CTX-M-27 extended-spectrum β-lactamase in a neonatal unit in Sousse, Tunisia. J Clin Microbiol, 34, 1037-1044. (Pubitemid 40364914)
14. Bourouis A, Dubois V, Coulange L, André C, Bejhadj C, Ben Moussa M, Quentin C, Belhadj O.(2009). First report of CTX-M-9 in a clinical isolate of Enterobacter cloacae in a Tunisian hospital. Path Biol, doi:10.1016/j.patbio. 2009.03.008.
15. Boyd DA, Tyler S, Christianson S, McGeer A, Muller MP, Willey BM, Bryce E, Gardam M, Nordmann P, Mulvey MR. (2004). Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extendedspectrum β-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada. Antimicrob. Agents Chemother 48, 3758-3764. (Pubitemid 39304600)
16. Bradford PA, Cherubin CE, Idemyor V, Rasmussen BA, Bush K. (1994). Multiply resistant Klebsiella pneumoniae strains from two Chicago hospitals: identifcation of the extended-spectrum TEM-12 and TEM-10 ceftazidime-hydrolyzing beta-lactamases in a single isolate. Antimicrob. Agents Chemother, 38, 761-766. (Pubitemid 24114015)
17. Bush K, Jacoby GA, Medeiros AA. (1995). A functional classifcation scheme for beta-lactamases and its correlation with molecular structure. Antimicrob Agents Chemother, 39, 1211-1233.
18. Bush K, Macalintal C, Rasmussen BA, Lee VJ, Yang Y. (1993). Kinetic interactions of tazobactam with β-lactamases from all major structural classes. Antimicrob Agents Chemother, 37, 851-858. (Pubitemid 23096890)
19. Carrër A, Poirel L, Eraksoy H, Cagatay AA, Badur S, Nordmann P. (2008). Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. Antimicrob Agents Chemother, 52, 2950-2954.
20. Castanheira M, Mendes RE, Rhomberg PR, Jones RN. (2008). Rapid emergence of blaCTX-M among Enterobacteriaceae in U.S. medical centers: molecular evaluation from the MYSTIC Program (2007). Microb Drug Resist, 14, 211-216.
21. Chouchani C, Ben Achour N, M'Charek A, Belhadj O. (2007). Cloning and sequencing of the class A β-lactamase gene (blaTEM-15) Located on a chromosomal Tn801 transposon. Diag Microbiol Infect Dis, 58, 459-463. (Pubitemid 47198401)
22. Chouchani C, Berlemont R, Masmoudi A, Galleni M, Frere J-M, Belhadj O, Ben-Mahrez K. (2006). A Novel extended-spectrum TEM-type β-lactamase (TEM-138) From Salmonella enterica serovar Infantis. Antimicrob Agents Chemother, 50, 3183-3185. (Pubitemid 44396434)
23. Corvec S, Poirel L, Naas T, Drugeon H, Nordmann P. (2007). Genetics and expression of the carbapenem-hydrolyzing oxacillinase gene blaOXA-23 in Acinetobacter baumannii. Antimicrob Agents Chemother, 51, 1530-1533. (Pubitemid 46586845)
24. Cuzon G, Naas T, Lesenne A, Benhammou M, Nordmann P. (2010). Plasmid-mediated carbapenem-hydrolysing OXA-48 β-lactamase in Klebsiella pneumoniae from Tunisia. Int J Antimicrob Agents, 36, 91-93.
25. Dahmen S, Bettaieb D, Mansour W, Boujaafar N, Bouallègue O, Arlet G. (2010). Characterization and molecular epidemiology of extended-spectrum β-lactamases in clinical isolates of Enterobacteriaceae in a Tunisian University Hospital. Microb Drug Resist, 16, 163-70.
26. Dahmen S, Poirel L, Mansour W, Bouallègue O, Nordmann P. (2009). Prevalence of plasmid-mediated quinolone resistance determinants in Enterobacteriaceae from Tunisia. Clin Microbiol Infect, 16, 1019-1023
27. Datta N, Kontomichalou P. (1965). Penicillinase synthesis controlled by infectious R factors in Enterobacteriaceae. Nature, 208, 239-241.
28. Doloy A, Verdet C, Gautier V, Decre D, Ronco E, Hammami A, Philippon A, Arlet G. (2006). Genetic environment of acquired blaACC-1 β-Lactamase gene in Enterobacteriaceae isolates. Antimicrob Agents Chemother, 50, 4177-4181. (Pubitemid 44865164)
29. Drawz SM, Bonomo RA. (2010). Tree Decades of β-Lactamase inhibitors. Clin Microbiol Rev, 23,160-201.
30. Easton CJ, Knowles JR. (1982). Inhibition of the RTEM β-lactamase from Escherichia coli. Interaction of the enzyme with derivatives of olivanic acid. Biochem, 21, 2857-2862. (Pubitemid 12067503)
31. Elhani D, Bakir L, Aouni M, Passet V, Arlet G, Brisse S, Weill F-X. (2010). Molecular epidemiology of extended-spectrum β-lactamase-producing Klebsiella pneumonia strains in a university hospital in Tunis, Tunisia, 1999-2005. Clin Microbiol Infect, 16, 157-164.
32. Fisher J, Belasco JG, Charnas RL, Khosla S, Knowles JR. (1980). β-Lactamase inactivation by mechanism-based reagents. Philos Trans R Soc Lond B Biol Sci, 289, 309-319.
33. Galleni M, Amicosante G, Frere JM. (1988). A survey of the kinetic parameters of class C β-lactamases. Cephalosporins and other β-lactam compounds. Biochem J, 255, 123-129.
34. Gavin PJ, Suseno MT, Tomson RB, Gaydos JM, Pierson CL, Halstead DC, Aslanzadeh J, Brecher S, Rotstein C, Brossette SE, Peterson LR. (2006). Clinical correlation of the CLSI susceptibility breakpoint for piperacillin-tazobactam against extended-spectrum-beta-lactamase- producing Escherichia coli and Klebsiella species. Antimicrob Agents Chemother, 50, 2244-2247. (Pubitemid 43807556)
35. Girlich D, Naas T, Nordmann P. (2004). Biochemical characterization of the naturally occurring oxacillinase OXA-50 of Pseudomonas aeruginosa. Antimicrob Agents Chemother, 48, 2043-2048. (Pubitemid 38691595)
36. Govinden U, Mocktar C, Moodley P, Sturm AW, Essack SY. (2007). Geographical evolution of the CTX-M β-lactamase- an update. Afr J Biotechnol, 6, 831-839. (Pubitemid 46607478)
37. Hammami A, Arlet G, Ben Redjeb S, Grimont F, Ben Hassen A, Rekik A, Philippon A. (1991). Nosocomial outbreak of acute gastroenteritis in a neonatal intensive care unit in Tunisia caused by multiply drug resistant Salmonella wien producing SHV-2 beta-lactamase. Eur J Clin Microbiol Infect Dis, 10, 641-646.
38. Hammami S, Gautier V, Ghozzi1 R, Da Costa A, Ben-Redjeb S, Arlet G. (2010). Diversity in VIM-2-encoding class 1 integrons and occasional blaSHV2a carriage in isolates of a persistent, multidrugresistant Pseudomonas aeruginosa clone from Tunis. Clin Microbiol Infect, 16, 189-193.
39. Helfand MS, Bethel CR, Hujer AM, Hujer KM, Anderson VE, Bonomo RA. (2003). Understanding resistance to β-lactams and β-lactamase inhibitors in the SHV β-lactamase: lessons from the mutagenesis of SER-130. J Biol Chem, 278, 52724-52729. (Pubitemid 38035869)
40. Jacobs C, Frere JM, Normark S. (1997). Cytosolic intermediates for cell wall biosynthesis and degradation control inducible β-lactam resistance in gram-negative bacteria. Cell, 88, 823-832. (Pubitemid 27164270)
41. Juan C, Gutierrez O, Oliver A, Ayestaran JI, Borrell N, Perez JL. (2005). Contribution of clonal dissemination and selection of mutants during therapy to Pseudomonas aeruginosa antimicrobial resistance in an intensive care unit setting. Clin Microbiol Infect, 11, 887-892. (Pubitemid 41535925)
42. Kalai Blagui S, Achour W, Abdeladhim A, Ben Hassen A. (2009). Identifcation of SHV-type extended spectrum β-lactamase genes in Pseudomonas aeruginosa by PCR-restriction fragment length polymorphism and insertion site restriction-PCR. Path Biol, 57, 420-424.
43. Kalai-Blagui S, Achour W, Abbassi MS, Bejaoui M, Abdeladhim A, Ben Hassen A. (2007). Nosocomial outbreak of OXA-18-producing Pseudomonas aeruginosa in Tunisia. Clin Microbiol Infect, 13, 794-800. (Pubitemid 47039913)
44. Ktari S, Arlet A, Verdet C, Jaoua S, Kachrid A, Ben Redjeb S, Mahjoubi-Rhimi F, Hammami A. (2009). Molecular epidemiology and genetic environment of acquired blaACC-1 in Salmonella enteric serotype Livingstone causing a large nosocomial outbreak in Tunisia. Mirob Drug Resist, 15, 279-286.
45. Ktari S, Arlet G, Mnif B, Gautier V, Mahjoubi F, Ben Jmeaa M, Bouaziz M, Hammami A. (2006). Emergence of multidrug-resistant Klebsiella pneumoniae isolates producing VIM-4 metallo-β-lactamase, CTX-M-15 extended-spectrum β-lactamase, and CMY-4 AmpC β-lactamase in a Tunisian University Hospital. Antimicrob Agents Chemother, 50, 4198-4201. (Pubitemid 44865170)
46. Labia R., Analysis of the blatoho gene coding for Toho-2-beta-lactamase. (1999). Antimicrob Agents Chemother, 43, 2576-2577.
47. Laraki N, Franceschini N, Rossolini GM, Santucci P, Meunier C, De Pauw E, Amicosante G, Frere JM, Galleni M. (1999). Biochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo-β-lactamase IMP-1 produced by Escherichia coli. Antimicrob Agents Chemother, 43, 902-906. (Pubitemid 29165755)
48. Lartigue MF, Fortineau N, Nordmann P. (2005). Spread of novel expanded-spectrum β-lactamases in Enterobacteriaceae in a university hospital in the Paris area, France. Clin Microbiol Infect, 11, 588-91. (Pubitemid 40895163)
49. Lauretti L, Riccio ML, Mazzariol A, Cornaglia G, Amicosante G, Fontana R, Rossolini GM. (1999). Cloning and characterization of blaVIM, a new integron-borne metallo-β-lactamase gene from a Pseudomonas aeruginosa clinical isolate. Antimicrob Agents Chemother, 43, 1584-1590. (Pubitemid 29331232)
50. Lavollay M, Mamlouk K, Frank T, Akpabie A, Burghofer B, Ben Redjeb S, Bercion R, Gautier V, Arlet G. (2006). Clonal dissemination of a CTX-M-15 β-lactamase-producing Escherichia coli strain in the Paris area, Tunis, and Bangui. Antimicrob Agents Chemother, 50, 2433-2438. (Pubitemid 43993183)
51. Lodise TP, Lomaestro JB, Rodvold KA, Danziger LH, Drusano GL. (2004). Pharmacodynamic profling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulation. Antimicrob Agents Chemother, 48, 4718-4724. (Pubitemid 39577677)
52. Makanera A, Arlet G, Gautier V, Manai M. (2003). Molecular epidemiology and characterization of plasmid-encoded β-lactamases produced by Tunisian clinical isolates of Salmonella enterica serotype Mbandaka resistant to broad-spectrum cephalosporins. J Clin Microbiol, 41, 2940-2945. (Pubitemid 36842282)
53. Mamlouk K, Boutiba-Ben Boubaker I, Gautier V, Vimont S, Picard B, Ben Redjeb S, Arlet G. (2006). Emergence and outbreaks of CTX-M β-lactamase- producing Escherichia coli and Klebsiella pneumoniae strains in a Tunisian Hospital. J Clin Microbiol, 44, 4049-4056. (Pubitemid 44737249)
54. Mansour W, Bouallegue O, Dahmen S, Boujaafar N. (2008a). Characterization of the resistance mechanism to β-lactams in Acinetobacter baumannii strains isolated in the university hospital Sahloul in Tunisia (2005). Path Biol, 56, 116-120
55. Mansour W, Dahmen S, Poirel L, Charf K, Bettaieb D, Boujaafar N, Bouallegue O. (2009a). Emergence of SHV-2a Extended-Spectrum β-Lactamases in Clinical Isolates of Pseudomonas aeruginosa in a University Hospital in Tunisia. Microb Drug Resist, 15, 295-301.
56. Mansour W, Poirel L, Bettaieb D, Bouallegue O, Boujaafar N, Nordmanna P. (2009b). Metallo-β-lactamase-producing Pseudomonas aeruginosa isolates in Tunisia. Diagn Microbiol Infect Dis, 64, 458-461.
57. Mansour W, Poirel L, Bettaieb D, Bouallegue O, Boujaafar N., Nordmann P. (2008b). issemination of OXA-23-producing and carbapenem-resistant Acinetobacter baumannii in a University Hospital in Tunisia. Microb Drug Resist, 14, 289-292.
58. Massova I, Mobashery S. (1998). Kinship and diversifcation of bacterial penicillin-binding proteins and β-lactamases. Antimicrob Agents Chemother, 42, 1-17. (Pubitemid 28053319)
59. Muang YT, Chang SC, Lauderdale TL, Yang AY, Wang JT. (2007). Molecular epidemiology of carbapenem resistant Pseudomonas aeruginosa carrying metallo-β-lactamase genes in Taiwan. Diagn Microbiol Infect Dis, 59, 211-216.
60. Mulvey MR, Boyd DA, Baker L, Mykytczuk O, Reis EM, Asensi MD, Rodrigues DP, Ng LK. (2004). Characterization of a Salmonella enterica serovar Agona strain harbouring a class 1 integron containing novel OXA-type β-lactamase (blaOXA-53) and 6′-N-aminoglycoside acetyltransferase genes [aac(6′)-I30]. J Antimicrob Chemother, 54, 354-359. (Pubitemid 39177453)
61. Papp-Wallace KM, Bethel CR, Distler A, Kasuboski C, Taracila M, Bonomo RA. (2010). Inhibitor resistance in the KPC-2 β-lactamase: a pre-eminent property of this class A β-lactamase. Antimicrob Agents Chemother, 54, 890-897.
62. Philippon A, G Arlet, Jacoby GA. (2002). Plasmid-determined AmpC-type beta-lactamases. Antimicrob Agents Chemother, 46, 1-11.
63. Pitout JD, Chow BL, Gregson DB, Laupland KB, Elsayed S, Church DL. (2007). Molecular epidemiology of metallo-beta-lactamase-producing Pseudomonas aeruginosa in the Calgary Health Region: emergence of VIM-2-producing isolates. J Clin Microbiol, 45, 294-298.
64. Pitout JD, Revathi G, Chow BL et al. (2008). Metallo-beta-lactamase- producing Pseudomonas aeruginosa isolated from a large tertiary centre in Kenya. Clin Microbiol Infect, 14, 755-759.
65. Poirel L, Mansour W, Bouallegue O., Nordmann P. (2008). Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. Antimicrob Agents Chemother, 52, 1613-1617 (Pubitemid 351614650)
66. Poirel L, Nordmann P. (2006). Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect, 12, 826-836. (Pubitemid 44151282)
67. Rhimi-Mahjoubi F, Bernier M, Arlet G, Ben Jemaa Z, Jouve P, Hammami A, Philippon A. (2002). Mise en évidence de la céphalosporinase plasmidique ACC-1 dans diférentes entérobactéries (Klebsiella pneumoniae, Proteus mirabilis, Salmonella) isolées dans un hôpital Tunisien (Sfax 1997-2000). Pathol Biol, 50, 7-11.
68. Segal H, Garny S, Elisha BG. (2005) Is ISAba1 customized for Acinetobacter? FEMS Microbiol Lett, 243, 425-429.
69. Sturenburg E, Kuhn A, Mack D, Laufs R. (2004). A novel extended-spectrum β-lactamase CTX-M-23 with a P167T substitution in the active-site omega loop associated with ceftazidime resistance. J Antimicrob Chemother, 54, 406-409. (Pubitemid 39177461)
70. Tenover FC, Mohammed MJ, Gorton TS, Dembek ZF. (1999). Detection and reporting of organisms producing extended-spectrum β-lactamases: survey of laboratories in Connecticut. J Clin Microbiol, 37, 4065-4070.
71. Verdet C, Arlet G, Ben Redjeb S, Ben Hassen A, Lagrange PH, Philippon A. (1998). Characterisation of CMY-4, an AmpC-type plasmid-mediated beta-lactamase in a Tunisian clinical isolate of Proteus mirabilis. FEMS Microbiol Lett, 169, 235-40. (Pubitemid 29050784)
72. Verdet C, Benzerara Y, Gautier V, Adam O, Ould-Hocine Z, Arlet G. (2006). Emergence of DHA-1-producing Klebsiella spp. in the Parisian region: genetic organization of the ampC and ampR genes originating from Morganella morganii. Antimicrob Agents Chemother, 50, 607-617. (Pubitemid 43190973)
73. Walsh TR, Toleman MA, Poirel L, Nordmann P. (2005). Metallo-β- lactamases: the quiet before the storm? Clin Microbiol Rev, 18, 306-325.
74. Walter MW, Felici A, Galleni M, Soto RP, Adlington RM, Baldwin JE, Frere JM, Gololobox M, Schofeld CJ. (1996). Trifuoromethyl alcohol and ketone inhibitors of metallo-β-lactamases. Bioorg Med Chem Lett, 6, 2455-2458. (Pubitemid 26345029)
75. Walther-Rasmussen J, Hoiby N. (2006). OXA-type carbapenemases. J Antimicrob Chemother, 57, 373-383. (Pubitemid 43240190)
76. Winokur PL, Vonstein DL, Hofman LJ, Uhlenhopp EK, Doern GV. (2001). Evidence for transfer of CMY-2 AmpC β-lactamase plasmids between Escherichia coli and Salmonella isolates from food animals and humans. Antimicrob Agents Chemother, 45, 2716-2722. (Pubitemid 32906662)