Emergence of SHV-2a extended-spectrum β-lactamases in clinical isolates of pseudomonas aeruginosa in a university hospital in tunisia

Microbial Drug Resistance

Volumn 15, Issue 4, 2009, Pages 295-301

  Mansour, Wejdene ^a   Dahmen, Safia ^a   Poirel, Laurent ^b   Charfi, Karama ^a   Bettaieb, Dalia ^a   Boujaafar, Noureddine ^a   Bouallegue, Olfa ^a  

^a Laboratory of Microbiology   (Tunisia)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AZTREONAM; BETA LACTAMASE; CEFOTAXIME; CEFPIROME; CEFTAZIDIME; CLOXACILLIN; IMIPENEM; PIPERACILLIN; SHV 2A ENZYME; TICARCILLIN; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM ISOLATE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LOCALIZATION; FEMALE; HUMAN; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; TUNISIA;

ANTI-BACTERIAL AGENTS; BASE SEQUENCE; BETA-LACTAMASES; CLOXACILLIN; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HOSPITALS, UNIVERSITY; HUMANS; ISOELECTRIC FOCUSING; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; TUNISIA;

ENTEROBACTERIACEAE; PSEUDOMONAS AERUGINOSA;

EID: 70350452562     PISSN: 10766294     EISSN: None     Source Type: Journal    
DOI: 10.1089/mdr.2009.0012     Document Type: Article

References (38)

1. Adrian, P.V., C.J. Thomson, K.P. Klugman, and S.G. Amyes. 2000. New gene cassettes for trimethoprim resistance, dfr13, and streptomycin-spectinomycin resistance, aadA4, inserted on a class 1 integron. Antimicrob. Agents Chemother. 44: 355-361.
2. Ait Tayeb, L., E. Ageron, F. Grimont, and P.A.D. Grimont. 2005. Molecular phylogeny of the genus Pseudomonas based on rpoB sequences and application for the identification of isolates. Res. Microbiol. 156:763-773.
3. Ben-Hamouda, T., and K. Ben-Mahrez. 2005. Predominance and evolution of blaSHV genes in Tunisian hospital isolates of Klebsiella pneumoniae. Arch. Inst. Pasteur Tunis. 82:31-38.
4. Ben Hamouda, T., T. Foulon, and K. Ben-Mahrez. 2004. Involvement of SHV-12 and SHV-2a encoding plasmids in outbreaks of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in Tunisian neonatal ward. Microb. Drug Resist. 10:132-138.
5. Chanawong, A.F., F.H. M'Zali, J. Heritage, A. Lulitanoud, and P.M. Hawkey. 2001. SHV-12, SHV-5, SHV-2a and VEβ-1 extended-spectrum β-lactamases in Gram-negative bacteria isolated in a university hospital in Thailand. J. Antimicrob. Chemother. 48:839-852.
6. Chen, H.Y., M. Yan, and D.M. Livermore. 1995. Mechanisms of resistance to β-lactam antibiotics amongst Pseudomonas aeruginosa isolates collected in the UK in 1993. J. Med. Microbiol. 43:300-309.
7. Crichton Pamela, B., D.C. Old, A. Taylor, and S.C. Rankin. 1996. Characterization of strains of Salmonella serotype Livingstone by multiple typing. J. Med. Microbiol. 44:325-331.
8. De Champs, C., L. Poirel, R. Bonnet, D. Sirot, C. Chanal, J. Sirot, and P. Nordmann. 2002. Prospective survey of betalactamases produced by ceftazidime-resistant Pseudomonas aeruginosa isolated in a French hospital in 2000. Antimicrob. Agents Chemother. 46:3031-3034.
9. GES-1 and a fused product of aac3-Ib=aac6'-Ib' gene cassettes in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 46:638-645.
10. El Amin, N., C.G. Giske, S. Jalal, B. Keijser, G. Kornvall, and B. Wretlind. 2005. Carbapenem resistance mechanisms in Pseudomonas aeruginosa: alterations of porin OprD and efflux proteins do not fully explain resistance patterns observed in clinical isolates. APMIS 113:187-196.
11. Girlich, D., T. Naas, A. Leelaporn, L. Poirel, M. Fennewald, and P. Nordmann. 2002. Nosocomial spread of the integronlocated veβ-1-like cassette encoding an extended-spectrum β-lactamase in Pseudomonas aeruginosa in Thailand. Clin. Infect. Dis. 34:175-182.
12. Girlich, D., T. Naas, and P. Nordmann. 2004. Biochemical characterization of the naturally occurring oxacillinase OXA- 50 of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 48:2043-2048.
13. Grundmann, H.J., K.J. Towner, L. Dijkshoorn, P. Gerner- Smidt, M. Maher, H. Seifert, and M. Vaneechoutte. 1997. Multicenter study using standardized protocols and reagents for evaluation of reproductibility of PCR-based fingerprinting of Acinetobacter spp. J. Clin. Microbiol. 35:3071-3077.
14. Jacoby, G.A., and A.A. Medeiros. 1991. More extended spectrum β--lactamases. Antimicrob. Agents Chemother. 35:1697-1704.
15. Jiang, X., Z. Zhang, M. Li, D. Zhou, F. Ruan, and Y. Lu. 2006. Detection of extended-spectrum β-lactamases in clinical isolates of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 50:2990-2995.
16. Kim, J., H.S. Shin, S.Y. Seol, and D.T. Cho. 2002. Relationship between blaSHV-12 and blaSHV-2a in Korea. J. Antimicrob. Chemother. 49:261-267.
17. Lee, S., Y.J. Park, M. Kim, H.K. Lee, K. Han, C.S. Kang, and M.W. Kang. 2005. Prevalence of Ambler class A and D beta-lactamases among clinical isolates of Pseudomonas aeruginosa in Korea. J. Antimicrob. Chemother. 56:122-127.
18. Livermore, D.M. 1995. Beta-lactamases in laboratory and clinical resistance. Clin. Microbiol. Rev. 8:557-584.
19. Livermore, D.M. 2002. Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare? Clin. Infect. Dis. 34:634-640.
20. Matthew, M., A.M. Harris, M.J. Marshall, and G.W. Ross. 1975. The use of analytical isoelectric focusing for detection and identification of beta-lactamases. J. Gen. Microbiol. 88:169-178.
21. Mavroidi, A., E. Tzelepi, A. Tsakris, V. Miriagou, D. Sofianou, L.S. Tzouvelekis. 2001. An integron-associated beta-lactamase (IBC-2) from Pseudomonas aeruginosa is a variant of the extended-spectrum beta-lactamase IBC-1. J. Antimicrob. Chemother. 48:627-630.
22. Naas, T., L. Philippon, L. Poirel, E. Ronco, and P. Nordmann. 1999. An SHV-derived extended-spectrum beta-lactamase in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 43:1281-1284. (Pubitemid 29214764)
23. Nordmann, P., T. Naas, N. Fortineau, and L. Poirel. 2007. Superbugs in the coming new decade; multidrug resistance and prospects for treatment of Staphylococcus aureus, Enterococcus spp. and Pseudomonas aeruginosa in 2010. Curr. Opin. Micobiol. 10:436-440.
24. Nuesch-Inderbinen, M.T., H. Hachler, and F.H. Kayser. 1995. New system based on site-directed mutagenesis for highly accurate comparison of resistance levels conferred by SHV β-lactamases. Antimicrob. Agents Chemother. 39: 1726-1730.
25. Philippon, L.N., T. Naas, A.T. Bouthors, V. Barakett, and P. Nordmann. 1997. OXA-18, a class D clavulanic-acid inhibited extended-spectrum beta-lactamase from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 41:2188-2195.
26. Podbielski, A., J. Schö nling, B. Melzer, K. Warnatz, and H.G. Leusch. 1991. Molecular characterization of a new plasmid encoded SHV-type β-lactamase (SHV-2 variant) conferring high level cefotaxime resistance upon K. pneumoniae. J. Gen. Microbiol. 137:569-578.
27. Poirel, L., L. Brinas, A. Verlinde, L. Ide, and P. Nordmann. 2005. BEL-1, a novel clavulanic acid-inhibited extendedspectrum beta-lactamase, and the class 1 integron In120 in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 49:3743-3748.
28. Poirel, L., L. Cabanne, H. Vahaboglu, and P. Nordmann. 2005. Genetic environment and expression of the extendedspectrum beta-lactamase blaPER-1 gene in Gram-negative bacteria. Antimicrob. Agents Chemother. 49:1708-1713.
29. Poirel, L., E. Lebessi, M. Castro, C. Fevre, M. Fonstoukou, and P. Nordmann. 2004. Nosocomial outbreak of extendedspectrum β-lactamase SHV-5-producing isolates of Pseudomonas aeruginosa in Athens, Greece. Antimicrob. Agents Chemother. 48:2277-2279.
30. Poirel, L., E. Ronco, T. Naas, and P. Nordmann. 1999. Extended-spectrum beta-lactamase TEM-4 in Pseudomonas aeruginosa. Clin. Microbiol. Infect. 5:651-652. (Pubitemid 29507423)
31. Poirel, L., V.O. Rotimi, E.M. Mokaddas, A. Karim, and P. Nordmann. 2001. VEβ-1-like extended-spectrum betalactamases in Pseudomonas aeruginosa, Kuwait. Emerg. Infect. Dis. 7:468-470.
32. Poirel, L., G.F. Weldhagen, C. De Champs, and P. Nordmann. 2002. A nosocomial outbreak of Pseudomonas aeruginosa isolates expressing the extended-spectrum β-lactamase GES-2 in South Africa. J. Antimicrob. Chemother. 49:561-565.
33. Sambrook, J., and D.W. Russel. 2001. in Molecular Cloning: A Laboratory Manual. 3rd edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
34. Sundstrom, L., C. Jansson, K. Bremer, E. Heikkila, B. Olsson-Liljequist, and O. Skold. 1995. A new dhfrVIII trimethoprim-resistance gene, flanking by IS26, whose product is remote from other dihydrofolate reductase parsimony analysis. Gene 154:7-14.
35. Tzelepi, E., A. Giakkoupi, D. Sofianou, V. Loukova, A. Kemeroglou, and A. Tsakris. 2000. Detection of extended- spectrum beta-lactamases in clinical isolates of Enterobacter cloacae and Enterobacter aerogenes. J. Clin. Microbiol. 38: 542-546.
36. Vahaboglu, H., R. Ozturk, G. Aygun, F. Coskunkan, A. Yaman, A. Kaygusuz, H. Leblebicioglu, I. Balik, K. Aydin, and M. Otkun. 1997. Widespread detection of PER-1-type extended-spectrum beta-lactamases among nosocomial Acinetobacter and Pseudomonas aeruginosa isolates in Turkey: a nationwide multicenter study. Antimicrob. Agents Chemother. 41:2265-2269.
37. Walter, D.J., E. Smith-Moland, R.V. Goering, N.D. Hanson, and P.D. Lister. 2004. Multidrug resistance associated with mexXY expression in clinical isolates of Pseudomonas aeruginosa from a Texas hospital. Diagn. Microbiol. Infect. Dis. 2004. 50:43-50.
38. Weldhagen, G.F., L. Poirel, and P. Nordmann. 2003. Ambler class A extended-spectrum-β-lactamases in Pseudomonas aeruginosa: novel developments and clinical impact. Antimicrob. Agents Chemother. 47:2385-2392.