Emergence and outbreaks of CTX-M β-lactamase-producing Escherichia coli and Klebsiella pneumoniae strains in a Tunisian hospital

Journal of Clinical Microbiology

Volumn 44, Issue 11, 2006, Pages 4049-4056

  Mamlouk, Kelthoum ^a,b   Boubaker, Ilhem Boutiba Ben ^a,b   Gautier, Valérie ^c   Vimont, Sophie ^c,d   Picard, Bertrand ^e   Ben Redjeb, Saida ^a,b   Arlet, Guillaume ^c,d,f  

^a UNIVERSITY OF TUNIS EL MANAR   (Tunisia)

^b CHARLES NICOLLE HOSPITAL   (Tunisia)

^c SORBONNE UNIVERSITÉ   (France)

^d ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^e AVICENNE HOSPITAL   (France)

^f HÔPITAL TENON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AZTREONAM; BETA LACTAMASE; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CEFTRIAXONE; CEPHALOSPORIN; CTX M BETA LACTAMASE; CTX M15 BETA LACTAMASE; CTX M16 BETA LACTAMASE; IMIPENEM; TICARCILLIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; BACTERIUM ISOLATION; CONTROLLED STUDY; ELECTROPORATION; EPIDEMIC; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; STRAIN IDENTIFICATION; TUNISIA;

BETA-LACTAMASES; CROSS INFECTION; ESCHERICHIA COLI; HUMANS; KLEBSIELLA PNEUMONIAE; PHYLOGENY; PLASMIDS; RETROSPECTIVE STUDIES; VIRULENCE;

ENTEROBACTERIACEAE; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE;

EID: 33750944215     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.01076-06     Document Type: Article

References (40)

1. Armand-Lefevre, L., V. Leflon-Guibout, J. Bredin, F. Barguellil, A. Amor, J. M. Pagès, and M.-H. Nicolas-Chanoine. 2003. Imipenem resistance in Salmonella enterica serovar Wien related to porin loss and CMY-4 β-lactamase production. Antimicrob. Agents Chemother. 47:1165-1168.
2. Blomberg, B., R. Jureen, K. P. Manji, B. S. Tamim, D. S. Mwakagile, W. K. Urassa, M. Fataki, V. Msangi, M. G. Tellevik, S. Y. Maselle, and N. Langeland. 2005. High rate of fatal cases of pediatric septicemia caused by gram-negative bacteria with extended-spectrum beta-lactamases in Dar es Salaam, Tanzania. J. Clin. Microbiol. 43:745-749.
3. Bonnet, R. 2004. Growing group of extended-spectrum β-lactamases: the CTX-M enzymes. Antimicrob. Agents Chemother. 48:1-14.
4. Bouallègue-Godet, O., Y. Ben Salem, L. Fabre, M. Demartin, P. A. Grimont, R. Mzoughi, and F.-X. Weill. 2005. Nosocomial outbreak caused by Salmonella enterica serotype Livingstone producing CTX-M-27 extended-spectrum β-lactamase in a neonatal unit in Sousse, Tunisia. J. Clin. Microbiol. 43:1037-1044.
5. Boutiba-Ben Boubaker, I., R. Ghozzi, H. Ben Abdallah, K. Mamlouk, A. Kamoun, and S. Ben Redjeb. 2004. Evolution of acquired-resistance to third-generation cephalosporins in Enterobacteriaceae in a Tunisian hospital 1993-2001. Clin. Microbiol. Infect. 10:665-667.
6. Boyd, D. A., S. Tyler, S. Christianson, A. McGeer, M. P. Muller, B. M. Willey, E. Bryce, M. Gardam, P. Nordmann, and M. R. Mulvey. 2004. Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum β-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada. Antimicrob. Agents Chemother. 48:3758-3764.
7. Bradford, P. A. 2001. Extended-spectrum β-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin. Microbiol. Rev. 14:933-951.
8. Branger, C., O. Zamfir, S. Geoffroy, G. Laurans, G. Arlet, H. V. Thien, S. Gouriou, B. Picard, and E. Denamur. 2005. Genetic background of Escherichia coli and extended-spectrum β-lactamase type. Emerg. Infect. Dis. 11:54-61.
9. Clermont, O., S. Bonacorsi, and E. Bingen. 2000. Rapid and simple determination of the Escherichia coli phylogenetic group. Appl. Environ. Microbiol. 66:4555-4558.
10. Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing; 15th informational supplement. Approved standard M2-A8 and M7-A6. Clinical and Laboratory Standards Institute, Wayne, Pa.
11. Eckert, C., V. Gautier, M. Saladin-Allard, N. Hidri, C. Verdet, Z. Ould-Hocine, G. Barnaud, F. Delisle, A. Rossier, T. Lambert, A. Philippen, and G. Ariel. 2004. Dissemination of CTX-M-type β-lactamases among clinical isolates of Enterobacteriaceae in Paris, France. Antimicrob. Agents Chemother. 48:1249-1255.
12. Fang, H., C. Lundberg, B. Olsson-Liljequist, G. Hedin, E. Lindback, A. Rosenberg, and J. Struwe. 2004. Molecular epidemiological analysis of Escherichia coli isolates producing extended-spectrum β-laetamases for identification of nosocomial outbreaks in Stockholm, Sweden. J. Clin. Microbiol. 42:5917-5920.
13. Frank, T., G. Arlet, V. Gautier, A. Talarmin, and R. Bercion. 2006. Extended-spectrum β-lactamase-producing Enterobacteriaceae, Central African Republic. Emerg. Infect. Dis. 12:863-865.
14. CTX-M-15-carrying element. Antimicrob. Agents Chemother. 49:441-443.
15. Greenacre, M. 1992. Correspondence analysis in medical research. Stat. Methods Med. Res. 1:97-117.
16. Guignot, J., J. Breard, M.-F. Bernet-Camard, I. Peiffer, B. J. Nowieki, A. L. Servin, and A.-B. Blanc-Potard. 2000. Pyclonephritogenic diffusely adhering Escherichia coli EC7372 harboring Dr-II adhesin carries classical uropathogenic virulence genes and promotes cell lysis and apoptosis in polarized epithelial caco-2ATC7 cells. Infect. Immun. 68:7018-7027.
17. Jarlier, V., M. H. Nicolas, G. Fournier, and A. Philippon. 1988. Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaecae: hospital prevalence and susceptibility patterns. Rev. Infect. Dis. 10:867-878.
18. Johnson, J. R., and A. L. Stell. 2000. Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise. J. Infect. Dis. 181:261-272.
19. E. coli, among Escherichia coli isolates from patients with urosepsis. Infect. Immun. 68:3040-3047.
20. Johnson, J. R., P. Delavari, M. Kuskowski, and A. L. Stell. 2001. Phylogenetic distribution of extraintestinal virulence-associated traits in Escherichia coli. J. Infect. Dis. 183:78-88.
21. Johnson, J. R., M. A. Kuskowski, K. Owens, A. Gajewski, and P. L. Winokur. 2003. Phylogenetic origin and virulence genotype in relation to resistance to fluoroquinolones and/or extended-spectrum cephalosporins and cephamycins among Escherichia coli isolates from animals and humans. J. Infect. Dis. 188:759-768.
22. Kao, J. S., D. M. Stucker, J. W. Warren, and H. L. Mobley. 1997. Pathogenicity island sequences of pyelonephritogenic Escherichia coli CFT073 are associated with virulent uropathogenic strains. Infect. Immun. 65:2812-2820.
23. Karisik, E., M. J. Ellington, R. Pike, R. E. Warren, D. M. Livermore, and N. Woodford. 2006. Molecular characterization of plasmids encoding CTX-M-15 β-lactamase from Escherichia coli strains in the United Kingdom. J. Antimicrob. Chemother. 58:665-668.
24. Kariuki, S., J. E. Corkill, G. Revathi, R. Musoke, and C. A. Hart. 2001. Molecular characterization of a novel plasmid-encoded cefotaximase (CTX-M-12) found in clinical Klebsiella pneumoniae isolates from Kenya. Antimicrob. Agents Chemother. 45:2141-2143.
25. Kassis-Chikhani, N., S. Vimont, K. Asselat, C. Trivalle, B. Minassian, C. Sengelin, V. Gautier, D. Mathieu, E. Dussaix, and G. Arlet. 2004. CTX-M beta-lactamase-producing Escherichia coli in long-term care facilities, France. Emerg. Infect. Dis. 10:1697-1698.
26. Kerrn, M. B., T. Klemmensen, N. Frimodt-Moller, and F. Espersen. 2002. Susceptibility of Danish Escherichia coli strains isolated from urinary tract infections and bacteraemia, and distribution of sul genes conferring sulphonamide resistance. J. Antimicroh. Chemother. 50:513-516.
27. Lavollay, M., K. Mamlouk, T. Frank, A. Akpabie, B. Burghoffer, S. Ben Redjeb, R. Bercion, V. Gautier, and G. Ariel. 2006. Clonal dissemination of a CTX-M-15 β-lactamase-producing Escherichia coli strain in the Paris area. Tunis, and Bangui. Antimicrob. Agents Chemother. 50:2433-2438.
28. Leflon-Guibout, V., C. Jurand, S. Bonacorsi, F. Espinasse, M. C. Guelfi, F. Duportail, B. Heym, E. Bingen, and M. H. Nicolas-Chanoine. 2004. Emergence and spread of three clonally related virulent isolates of CTX-M-15-producing Escherichia coli with variable resistance to aminoglycosides and tetracycline in a French geriatric hospital. Antimicrob. Agents Chemother. 48:3736-3742.
29. Muller, M., A. McGeer, B. M. Willey, D. Reynolds, R. Malanczyj, M. Silverman, M. A. Green, and M. Culf. 2002. Outbreaks of multi-drug resistant Escherichia coli in long-term care facilities in the Durham, York, and Toronto regions of Ontario, 2000-2002. Can. Commun. Dis. Rep. 28:113-118.
30. Mulvey, M. R., E. Bryce, D. Boyd, M. Ofner-Agostini, S. Christianson, A. E. Simor, S. Paton, and The Canadian Hospital Epidemiology Committee of The Canadian Nosocomial Infection Surveillance Program, Health Canada. 2004. Ambler class A extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella spp. in Canadian hospitals. Antimicrob. Agents Chemother. 48:1204-1214.
31. Naas, T., A. Lezzar, C. Bentchouala, F. Smati, J. M. Scheftel, H. Monteil, and P. Nordmann. 2005. Multidrug-resistant Salmonella enterica serotype Senftenberg isolates producing CTX-M β-lactamases from Constantine, Algeria. J. Antimicrob. Chemother. 56:439-440.
32. Pitout, J. D. D., K. B. Laupland, D. L. Church, M. L. Menard, and J. R. Johnson. 2005. Virulence factors of Escherichia coli that produce CTX-M-type extended-spectrum β-lactamases. Antimicrob. Agents Chemother. 49:4667-4670.
33. Pitout, J. D. D., D. B. Gregson, D. L. Church, S. Elsayed, and K. B. Laupland. 2005. Community-wide outbreaks of clonally related CTX-M-14 β-lactamase-producing Escherichia coli strains in the Calgary Health Region. J. Clin. Microbiol. 43:2844-2849.
34. Poirel, L., M. Gniadkowski, and P. Nordmann. 2002. Biochemical analysis of the ceftazidime-hydrolysing extended-spectrum beta-lactamase CTX-M-15 and of its structurally related beta-lactamase CTX-M-3. J. Antimicrob. Chemother. 50:1031-1034.
35. Ruiz, J., K. Simon, J. P. Horcajada, M. Velasco, M. Barranco, G. Roig, A. Moreno-Martinez, J. A. Martinez, T. Jimenez de Anta, J. Mensa, and J. Vila. 2002. Differences in virulence factors among clinical isolates of Escherichia coli causing cystitis and pyelonephritis in women and prostatitis in men. J. Clin. Microbiol. 40:4445-4449.
36. Saladin, M., V. T. Cao, T. Lambert, J. L. Donay, J. L. Herrmann, Z. Ould-Hocine, C. Verdet, F. Delisle, A. Philippen, and G. Arlet. 2002. Diversity of CTX-M beta-lactamases and their promoter regions from Enterobacteriaceae isolated in three Parisian hospitals. FEMS Microbiol. Lett. 209:161-168.
37. Soge, O. O., A. M. Queenan, K. K. Ojo, B. A. Adeniyi, and M. C. Roberts. 2006. CTX-M-15 extended-spectrum β-lactamase from Nigerian Klebsiella pneumonia. J. Antimicrob. Chemother. 57:24-30.
38. Tenover, F. C., R. D. Arbeit, R. V. Goering, P. A. Mickelsen, B. E. Murray, D. H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33:2233-2239.
39. Weill, F. X., J. D. Perrier-Gros-Claude, M. Demartin, S. Coignard, and P. Grimont. 2004. Characterization of extended-spectrum-β-lactamase (CTX-M-15)-producing strains of Salmonella enterica isolated in France and Senegal. FEMS Microbiol. Lett. 238:353-358.
40. Woodford, N., M. E. Ward, M. E. Kaufmann, J. Turton, E. J. Fagan, D. James, A. P. Johnson, R. Pike, M. Warner, T. Cheasty, A. Pearson, S. Harry, J. B. Leach, A. Loughrey, J. A. Lowes, R. E. Warren, and D. M. Livermore. 2004. Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum β-lactamases in the UK. J. Antimicrob. Chemother. 54:735-743.