Geographical evolution of the CTX-M β-lactamase - An update

African Journal of Biotechnology

Volumn 6, Issue 7, 2007, Pages 831-839

  Govinden, U ^a   Mocktar, C ^a   Moodley, P ^b   Sturm, A W ^b   Essack, S Y ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

CTX M lactamase; Epidemiology; Geographic evolution

Indexed keywords

CEFOTAXIME; CTX M LACTAMASE; EXTENDED SPECTRUM BETA LACTAMASE; ISOENZYME; PENICILLINASE; UNCLASSIFIED DRUG;

AFRICA; AMINO ACID SUBSTITUTION; ASIA; AUSTRALIA; BACTERIAL GENE; BACTERIAL GENETICS; DRUG HYDROLYSIS; ENTEROBACTERIACEAE; ENZYME ACTIVITY; EUROPE; GENE MUTATION; GENE TRANSFER; GENETIC EPIDEMIOLOGY; GEOGRAPHIC DISTRIBUTION; MIDDLE EAST; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; REVIEW; WESTERN HEMISPHERE;

EID: 34247239377     PISSN: None     EISSN: 16845315     Source Type: Journal    
DOI: None     Document Type: Review

References (63)

1. Abdalhamid B, Pitout DD, Moland ES, Hanson ND (2004). Community disease caused by Citrobacter freundii producing a novel CTX-M β-lactamase, CTX-M-30 in Canada. Antimicrob. Agents Chemother. 48: 4435-4437.
2. Ahmed AM, Nakano H, Shimamoto T (2004). The first characterization of extended-spectrum β-lactamase producing Salmonella in Japan. J. Antimicrob. Chemother. 57: 283-284.
3. Al-Agamy MH, Ashour ME, Wiegand I (2006). First description of CTX-M β-lactamase-producing clinical Escherichia coli isolates from Egypt. Int. J. Antimicrob. Agents 27: 545-548.
4. Bae IK, Lee BH, Hwang HY, Jeong SH, Hong SG, Chang CL, Kwak HS, Kim HJ, Youn H (2006). A novel ceftazidime-hydrolysing extended-spectrum β-lactamase, CTX-M-54, with a single amino acid substitution at position 167 in the omega loop. J. Antimicrob. Chemother. 58: 315-319.
5. Bonnet R, Sampaio JLM, Labia R, De Champs C, Sirot D, Chanal C, Sirot R (2000). A novel CTX-M β-lactamase (CTX-M-8) in cefotaxime-resistant Enterobacteriaceae isolated in Brazil. Antimicrob. Agents Chemother. 44: 1936-1942.
6. Bonnet R, Dutour C, Sampaio JLM, Chanal C, Sirot D, Labia R, De Champs C, Sirot J (2001). Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240→Gly. Antimicrob. Agents Chemother. 45: 2269-2275.
7. Bonnet R (2004). Growing group of extended-spectrum β-lactamases: the CTX-M enzymes. Antimicrob. Agents Chemother. 48: 1-14.
8. Blomberg B, Jureen R, Manji KP, Tamin BS, Mwakagile DSM, Urassa WK, Fataki M, Msangi V, Tellevik MG, Maselle SY, Langeland N (2005). High rate of fatal cases of paediatric septicemia caused by gram-negative bacteria with extended-spectrum β-lactamases in Dar es Salaam, Tanzania. J. Clin. Microbiol. 43: 745-749.
9. Cartelle M, Thomas MD, Molina F, Moure R, Villaneuva R, Bou G (2004). High-level resistance to ceftazidime conferred by a novel enzyme, CTX-M-32, derived from CTX-M-1 through a single Asp240Gly substitution. Antimicrob. Agents Chemother. 48: 2308-2313.
10. PER-2 β-lactamase genes in clinical isolates from Bolivian hospitals. J. Antimicrob. Chemother. 57: 975-978.
11. Chen Y, Delmas J, Sirot J, Shoichet B, Bonnet R (2005). Atomic resolution structures of CTX-M β-lactamases: extended spectrum activities from increased mobility and decreased stability. J. Mol. Biol. 348: 349-362.
12. Chmelnitsky I, Carmeli Y, Leavitt A, Schwaber MJ, Navon-Venezia S (2005). CTX-M-2 and a new CTX-M-39 enzyme are the major extended-spectrum β-lactamases in multiple Escherichia coli clones isolated in Tel Aviv, Israel. Antimicrob. Agents Chemother. 49: 4745-4750.
13. Conceicao T, Brizio A, Duarte A, Lito LM, Cristino JM, Salgado MJ (2005). First description of CTX-M-15 producing Klebsiella pneumoniae in Portugal. Antimicrob. Agents Chemother. 49: 477-478.
14. Delmas J, Robin F, Carvalho F, Mongaret C, Bonnet R (2006). Prediction of the evolution of ceftazidime resistance in extended-spectrum β-lactamase CTX-M-9. Antimicrob. Agents Chemother. 50: 731-738.
15. CTX-M genes. J. Antimicrob. Chemother. 57: 14-23.
16. Eisener A, Fagan EJ, Feierl G, Kessler HH, Marth E, Livermore DM, Woodford N (2006). Emergence of Enterobacteriaceae isolates producing CTX-M extended-spectrum β-lactamase in Austria. Antimicrob. Agents Chemother. 40: 785-787.
17. Elliot E, Brink AJ, Greune JV, Els Z, Woodford N, Turton J, Waner M, Livermore D (2006). In vivo development of ertapenem resistance in a patient with pneumoniae caused by Klebsiella pneumoniae with an extended-spectrum β-lactamase. Clin. Infect. Dis. 42: 95-98.
18. Frank T, Arlet G, Gautier V, Talarmin A, Bercion R (2006). Extended-spectrum β-lactamase-producing Enterobacteriaceae in Central African Republic. Emerg. Infect. Dis. 12: 863-864.
19. Godet OB, Salem YB, Fabre L, Demartin M, Grimont PAD, Mzoughi R, Weill FX (2005). Nosocomial outbreak caused by Salmonella enterica serotype Livingstone producing CTX-M-27 in a neonatal unit in Sousse, Tunisia. J. Clin. Microbiol. 43: 1037-1044.
20. Govinden U, Mocktar C, Moodley P, Sturm AW, Essack SY (2006). CTX-M-37 in Salmonella enterica serotype Isangi from Durban, South Africa. Int. J. Antimicrob. Agents 28: 288-291.
21. Hernandez JR, Martinez L, Canton R, Coque TM, Pascual A and the Spanish group for nosocomial infections (2005). Nationwide study of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum β-lactamases in Spain. Antimicrob. Agents Chemother. 49: 2122-2125.
22. Hopkins KL, Graham AD, Threlfall EJ (2006). Novel plasmid-mediated CTX-M-8 subgroup extended-spectrum β-lactamase (CTX-M-40) isolated in the UK. Int. J. Antimicrob. Agents 27: 570-575.
23. Ishii Y, Ohno A, Taguchi H, Imajo S, Ishiguro M, Matsuzawa H (1995).Cloning and sequence of the gene encoding a cefotaxime-hydrolyzing class A beta-lactamase isolated from Escherichia coli Antimicrob. Agents Chemother. 39: 2269-2275.
24. Kim J, Lim JM, Jeong YS, Seol SY (2005). Occurrence of CTX-M-3, CTX-M-15, CTX-M-14, and CTX-M-9 Extended-Spectrum ß-Lactamases in Enterobacteriaceae Clinical Isolates in Korea. Antimicrob. Agents Chemother. 49: 1572-1575.
25. Karim A, Poirel A, Nagarajan S, Nordman P (2001). Plasmid-mediated extended-spectrum β-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISECP1. FEMS Microbiol. Lett. 201: 237-241.
26. Kariuki S, Corkill JE, Revathi G, Musoke R, Hart CA (2001) Molecular characterization of a novel plasmid-encoded cefotaximase (CTX-M-12) found in clinical Klebsiella pneumoniae isolates from Kenya. Antimicrob. Agents Chemother. 45: 2141-2143.
27. Kariuki S, Revathi G, Kariuki N, Muyodi J, Mwituria J, Munyalo A, Kagendo D, Murungi L, Hart CA (2005). Increasing prevalence of multidrug-resistant non-typhoidal salmonellae, Kenya, 1994-2003. Int. J. Antimicrob. Agents 25: 38-43.
28. Kim J, Lin YM, Jeong YS, Seol SY (2005). Occurrence of CTX-M-3, CTX-M-15, CTX-M-14 and CTX-M-9 extended-spectrum β-lactamases in Enterobacteriaceae clinical isolates in Korea, Antimicrob. Agents Chemother. 49: 1572-1575.
29. Koh TH, Wang GCY, Sng LH, Yi Z, Koh TY (2004). CTX-M and plasmid-mediated AmpC-producing Enterobacteriaceae, Singapore. Emerg. Infect. Dis. 10: 1172-1173.
30. CTX-M of Kluyvera ascorbata. Antimicrob. Agents Chemother. 50: 1282-1286.
31. Leflon-Guibout V, Jurand C, Bonacorsi S, Espinasse F, Guelfi MC, Duportail F, Heym B, Bingen E, Chanoin MHN (2004). Emergence and spread of three clonally related virulent isolates of CTX-M-15-producing Escherichia coli with variable resistance to aminoglycosides and tetracycline in a French geriatric hospital. Antimicrob. Agents Chemother. 48: 3736-3742.
32. Liebana E, Batchelor M, Torres C, Brinas L, Lagos LA, Abdalhamid B, Hanson ND, Martinez-Urtaza JM (2004). Pediatric infection due to multiresistant Salmonella enterica serotype Infantis in Honduras. J. Clin. Microbiol. 42: 4885-4888.
33. Livermore DM, Hawkey M (2005). CTX-M: changing the face of ESBLs in the UK. J. Antimicrob. Chemother. 56:451-454.
34. Li H, Li JB (2005). Detection of five novel CTX-M-type extended-spectrum β-lactamases with one to three CTX-M-14 point mutations in isolates from Hefei, Anhui Province, China. J. Clin. Microbiol. 43: 4301-4302
35. Ma L, Ishii Y, Ishiguro M, Matsuzawa H, Yamaguchi K (1998). Cloning and sequencing of the gene encoding Toho-2, a class A β-lactamase preferentially inhibited by tazobactam. Antimicrob. Agents Chemother. 42: 1181-1186.
36. Mena A, Plasencia V, Gracia L, Ignacio J, Albert AS, Borrell N, Perez JL, Oliver A (2006). Characterization of a large outbreak by CTX-M-1-producing Klebsiella pneumoniae and mechanisms leading to in vivo carbapenem resistance development. J. Clin. Microbiol. 44: 2831-2837.
37. Miriagou V, Tassios PT, Legakis NJ, Tzouvelekis LS (2004). Expanded-spectrum cephalosporin resistace in non-typhoidal Salmonella. Int. J. Antimicrob. Agents 23: 547-555.
38. Morris D, Whelan M, Corbett-Feeney G, Cormican M, Hawkey P, Li X, Doran G (2006) First report of extended-spectrum β-lactamase-producing Salmonella enterica isolates in Ireland. Antimicrob. Agents Chemother. 50: 1608-1609.
39. Mugnaioli C, Luzzaro F, De Luca F, Brigante G, Amicosante G, Rossolini GM (2005). Dissemination of CTX-M-type extended-spectrum β-lactamase genes to unusual hosts. J. Clin. Microbiol. 42: 4183-4185.
40. Munday CJ, Boyd DA, Brenwald N, Miller M, Andrews JM, Wise R, Mulvey MR, Hawkey PM (2004). Molecular and kinetic comparison of the novel extended-spectrum β-lactamases CTX-M-25 and CTXM-26. Antimicrob. Agents Chemother. 48: 4829-4834.
41. Moubareck C, Daoud Z, Hakime NI, Hamze M, Mangeney N, Matta H, Mokhbat E, Raymond R, Sarkis DK, Populaire FD (2005). Countrywide spread of community- and hospital-acquired extended-spectrum β-lactamase (CTX-M-15) producing Enterobactericeae in Lebanon. J. Clin. Microbiol. 43: 3309-3313.
42. Naiemi NA, Bart A, De Jong MD, Vandenbroucke-Gruls C.M, Rietra PJGM, Depets-Ossenkopp YJ, Wever PC, Spanjaard L, Bos AJ, Dium B. (2006). Widely distributed and predominant CTX-M extended-spectrum β-lactamases in Amsterdam, the Netherlands. J. Clin. Microbiol. 43: 3012-3014.
43. Pagani L, Dell' Amico E, Migliavacca R, D'Andrea MM, Giacobone E, Amicosante G, Romero E, Rossolini GM (2003). Multiple CTX-M-type extended-spectrum β-lactamases in nosocomial isolates of Enterobacteriaceae from a hospital in northern Italy. J. Clin. Microbiol. 41: 4264-4269.
44. Paterson DL, Hujer KM, Hujer AM, Yeiser B, Bonomo MD, Rice LB, Bonomo RA and the international Klebsiella study group (2003). Extended-spectrum β-lactamases in Klebsiella pneumoniae blood-stream isolates from seven countries. Dominance and widespread prevalence of SHV- and CTX-M-type β-lactamases. Antimicrob. Agents Chemother. 47: 3554-3564.
45. Gangoué-Piéboji J, Bedenic B, Shiro SK, Randegger C, Adiogo D, Ngassam P, Ndumbe P, Hachler H (2005). Extended-spectrum β-lactamase producing Enterobacteriaceae in Yaounde Cameroon. J. Clin. Microbiol. 43: 3273-3277.
46. Pitout JDD, Nordman P, Laupland KB, Poirel L (2005 a). Emergence of Enterobacteriaceae producing extended-spectrum β-lactamases in the community. J. Antimicrob. Chemother. 56: 52-59.
47. Pitout JDD, Gregson DB, Church DL, Elsayed S, Laupland KB (2005b). Community-wide outbreaks of clonally related CTX-M-14 β-lactamase-producing Escherichia coli strains in the Calgary health region. J. Clin. Microbiol. 43: 2844-2849.
48. Poirel L, Naas T, Thomas I, Karim A, Bingen E, Nordman P (2001). CTX-M-type extended-spectrum β-lactamase that hydrolyzes ceftazidime through a single amino acid substitution in the omega loop. Antimicrob. Agents Chemother. 45: 3355-3361.
49. Pottumarthy S, Yu Y, Sader HS, Jones RN, Chen M (2005). Susceptibility testing accuracy of a CTX-M-type extended-spectrum β-lactamase organism-producing population of Enterobacteriaceae: intermethod analysis for 9 β-lactams. Diag. Microbiol. Infect. Dis. 53: 131-141.
50. Quinteros M, Radice M, Gardella N, Rodriguez M, Costa N, Korbenfeld D, Couto E, Gutkind G, and the microbiology study group (2003). Extended-spectrum β-lactamases in Enterobacteriaceae in Buenos Aires, Argentina, public hospitals. Antimicrob. Agents Chemother. 47: 2864-2867.
51. Rasmussen JW, Hoiby N (2004). Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum β-lactamases. Can. J. Microbiol. 50: 137-165
52. Shibata N, Kurokawa H, Doi Y, Yagi T, Yamane K, Wachino JI, Suzuki S, Kimura K, Ishikawa S, Kato H, Ozawa Y, Shibayama K, Kai K, Konda T, Arakawa Y (2006). PCR classification of CTX-M-type β-lactamase genes identified in clinically isolated gram-negative bacilli in Japan. Antimicrob. Agents Chemother. 50: 791-795.
53. Shimamura T, Ibuka A, Fushinobu S, Wakagi T, Ishiguro M, Ishii Y, Matsuzawa H (2002). Acyl-intermediate structures of the extended-spectrum class A β-lactamase, Toho-1 in complex with cefotaxime, cephalothin and benzylpenicillin. J. Biol. Chem. 277: 46601-46608.
54. Simarro E, Navarro F, Ruiz J, Miro E, Gomez J, Mirelis B (2000). Salmonella enterica serovar Virchow with CTX-M-like β-lactamase in Spain. J. Clin. Microbiol. 38: 4676-4678.
55. Soge OO, Queenan AM, Ojo KK, Adeniyi BA, Roberts MC (2006). CTX-M-15 extended spectrum β-lactamase from Nigerian Klebsiella pneumoniae. J. Animicrob. Chemother. 57: 24-30.
56. Sonnevend A, Dhaheri KA, Mag T, Herpay M, Kolodziejek J, Noworthy N, Usmani A, Sheikh FA, Pai T (2006). CTX-M-15-producing multidrug-resistant enteroaggregative Escherichia coli in the United Arab Emirates. Clin. Microbiol. Infect. 12: 582.
57. Stürenburg E, Mack D (2003). Extended-spectrum β-lactamases: implications for the clinical microbioloby laboratory, therapy and infection control. J. Infect. 47: 273-295
58. Stürenburg E, Kuhn A, Mack D, Laufs R (2004). A novel extended-spectrum β-lactamase CTX-M-23 with a P167T substitution in the active-site omega loop associated with ceftazidime resistance. J. Antimicrob. Chemother. 54:406-409.
59. Tzouvelekis LS, Tzelepi E, Tassios PT, Legakis NJ (2000). CTX-M-type β-lactamases: an emerging group of extended -spectrum enzymes. Int. J. Antimicrob. Agents 14: 137-142.
60. Villegas MV, Correa A, Perez F, Zuluaga T, Radice M, Gutkind G, Casellas JM, Ayala J, Lolans K, Quinn JP and the Colombian nosocomial resistance study group (2004). CTX-M-12 β-lactamase in a Klebsiella pneumoniae clinical isolate in Colombia. Antimicrob. Agents Chemother. 48: 629-631.
61. Wu TL, Chia JH, Su LH, Kuo AJ, Chu C, Chiu CH (2003). Dissemination of extended-spectrum β-lactamase-producing Enterobacteriaceae in paediatric intensive care units J. Clin. Microbiol. 41: 4836-4838
62. Yan JJ, Hsueh PR, Lu JJ, Chang FY, Shyr JM, Wan JH, Liu YC, Chuang YC, Yang YC, Tsao SM, Wu HH, Wang LS, Lin TP, Wu HM, Chen HM, Wu JJ (2006). Extended-spectrum β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae from seven medical centres in Taiwan. Antimicrob. Agents Chemother. 50: 1861-1864.
63. Yong D, Lim YS, Yum JH, Lee H, Lee K, Kim EC, Lee BK, Chong Y (2005). Nosocomial outbreak of pediatric gastroenteritis cause by CTX-M-14 type extended-spectrum β-lactamase-producing strains of Salmonella enterica serovar London. J. Clin. Microbiol. 43: 3519-3521.