Faecal microbiota and short-chain fatty acid levels in faeces from infants with cow's milk protein allergy

International Archives of Allergy and Immunology

Volumn 156, Issue 3, 2011, Pages 325-332

  Thompson Chagoyan, Oscar C ^a   Fallani, Matteo ^c   Maldonado, José ^b   Vieites, José M ^a   Khanna, Sheila ^d   Edwards, Christine ^d   Doré, Joël ^c   Gil, Angel ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^c CEMAGREF   (France)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Allergy and immunology, child; Fatty acids; Gut microbiota; Intestinal microflora; Intestine, infants; Microbiology; Milk hypersensitivity; Short chain fatty acids

Indexed keywords

ACETIC ACID; ALPHA LACTALBUMIN; AMMONIA; BETA LACTOGLOBULIN; BIOLOGICAL MARKER; BUTYRIC ACID; CASEIN; MILK PROTEIN; PROPIONIC ACID; RIBOSOME RNA; SHORT CHAIN FATTY ACID;

ARTICLE; BACTERIAL CELL; BACTEROIDES; BIFIDOBACTERIUM; BIOCHEMICAL COMPOSITION; CLOSTRIDIUM; CLOSTRIDIUM COCCOIDES; CLOSTRIDIUM PERFRINGENS; COW MILK PROTEIN ALLERGY; ENZYME MECHANISM; FECES LEVEL; FECES MICROFLORA; FEMALE; FERMENTATION; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GAS LIQUID CHROMATOGRAPHY; HUMAN; INFANT; INTESTINE FLORA; LACTOBACILLUS; MAJOR CLINICAL STUDY; MALE; MILK ALLERGY; OLIGONUCLEOTIDE PROBE; PATHOGENESIS; PH; PRIORITY JOURNAL; STREPTOCOCCUS;

ACTINOBACTERIA; AMMONIA; BUTYRIC ACID; CLOSTRIDIUM; FATTY ACIDS, VOLATILE; FECES; FEMALE; HUMANS; INFANT; INTESTINES; MALE; METAGENOME; MILK HYPERSENSITIVITY; MILK PROTEINS;

EID: 79959665121     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000323893     Document Type: Article

References (38)

1. Høst A: Frecuency of cow's milk allergy in childhood. Ann Allergy 2002; 89(6 suppl 1): 33-37. (Pubitemid 36183828)
2. Penders J, Stobberingh EE, van den Brandt PA, Thijs C: The role of the intestinal microbiota in the development of atopic disorders. Allergy 2007; 62: 1223-1236. (Pubitemid 47537504)
3. Björkstén B, Naaber P, Sepp E, Mikelsaar M: The intestinal microflora in allergy Estonian and Swedish 2-year-old children. Clin Exp Allergy 1999; 29: 342-346. (Pubitemid 29145134)
4. Björkstén B, Sepp E, Julge K, Voor T, Mikelsaar M: Allergy development and the intestinal microflora during the first year of life. J Allergy Clin Immunol 2001; 108: 516-520. (Pubitemid 32978019)
5. Ouwehand AC, Isolauri E, He F, Hashimoto H, Benno Y, Salminen S: Differences in Bifidobacterium flora composition in allergic and healthy infants. J Allergy Clin Immunol 2001; 108: 144-145.
6. Hayashi H, Sakamoto M, Benno Y: Phylogenetic analysis of the gut microbiota using 16S rDNA clone libraries and strictly anaerobic cultural based methods. Microbiol Immunol 2002; 46: 535-548. (Pubitemid 34947852)
7. Rigottier-Gois L, Le Bourhis AG, Gramet G, Rochet V, Doré J: Fluorescent hybridisation combined with FC and hybridisation of total RNA to analyse the composition of microbial communities in human faeces using 16S rRNA probes. FEMS Microbiol Ecol 2003; 43: 237-245. (Pubitemid 36197884)
8. Kirjavainen PV, Apostolou E, Arvola T, Salminen S, Gibson GR, Isolauri E: Characterizing the composition of intestinal microflora as a prospective treatment targed in infant allergy disease. FEMS Immunol Med Microbiol 2001; 32: 1-7. (Pubitemid 34025068)
9. Kalliomäki M, Kirjavainen P, Eerola E, Kero P, Salminen S, Isolauri E: Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing. J Allergy Clin Immunol 2001; 107: 129-134. (Pubitemid 32105256)
10. Mah KW, Björkstén B, Lee BW, van Bever HP, Shek LP, Tan TN, Lee YK, Chua KY: Distinct pattern of commensal gut microbiota in toddlers with eczema. Int Arch Allergy Immunol 2006; 140: 157-163. (Pubitemid 43725810)
11. Parret AM, Edwards CA, Lokerse E: Colonic fermentation capacity in vitro: Development during weaning in breast-fed infants is slower for complex carbohydrates than for sugars. Am J Clin Nutr 1997; 65: 927-923.
12. Böttcher MF, Norin EK, Sandin A, Midtvedt T, Björkstén B: Microflora-associated characteristics in faeces from allergic and nonallergic infants. Clin Exp Allergy 2000; 30: 1590-1596.
13. Sandin A, Brabäck L, Norin E, Björkstén B: Faecal short chain fatty acid pattern and allergy in early childhood. Acta Paediatr 2009; 98: 823-827.
14. Rochet V, Rigottier-Gois L, Beguet F, Doré J: Composition of human intestinal flora analysed by fluorescent in situ hybridisation using group-specific 16S rRNA-targeted oligonucleotide probes. Genet Selec Evol 2001; 33:S339-S352. (Pubitemid 34007738)
15. Rigottier-Gois L, Rochet V, Garrec N, Suau A, Doré J: Enumeration of Bacteroides species in human faeces by fluorescent in situ hybridisation combined with flow cytometry using 16S rRNA probes. Syst Appl Microbiol 2003; 26: 110-118.
16. Amann RI, Krumholz L, Stahl DA: Fluorescent- oligonucleotide probing of whole cells for determinative, phylogenetic, and environmental studies in microbiology. J Bacteriol 1990; 172: 762-770. (Pubitemid 20070387)
17. Walner G, Amann R, Beisker W: Optimizing fluorescent in situ hybridization with ribosomal- RNA-targeted oligonucleotide probes for flow cytometric identification of microorganism. Cytometry 1993; 14: 136-143. (Pubitemid 23042736)
18. Fallani M, Rigottier-Gois L, Aguilera M, Bridonneau C, Collignon A, Edwards CA, Corthier G, Doré J: Clostridium difficile and Clostridium perfringens species detected in infant faecal microbiota using 16S rRNA targeted probes. J Microbiol Methods 2006; 67: 150-161. (Pubitemid 44279111)
19. Harmsen HJ, Wildebwer-Veloo AC, Grijpstra J, Knol J, Degener JE, Welling GW: Development of 16S rRNA-based probes for the Coriobacterium group and the Atopobium cluster and their application for enumeration of Coriobacteriaceae in human faeces from volunteers of different age groups. Appl Environ Microbiol 2000; 66: 4523-4527.
20. Franks AH, Harmsen HJM, Raangs GC, Jansen GJ, Schut F, Welling GW: Variations of bacterial populations in human faeces measured by fluorescent in situ hybridization with group-specific 16S rRNA-targeted oligonucleotide probes. Appl Environ Microbiol 1998; 64: 3336-3345. (Pubitemid 28411456)
21. Langendijk PS, Schut F, Jansen GJ, Raangs GC, Kamphuis GR, Wilkinson MHF, Welling GW: Quantitative fluorescence in situ hybridization of Bifidobacterium spp with genius-specific 16S ribosomal-RNA targeted probes and its application in faecal samples. Appl Environ Microbiol 1995; 61: 3069-3075.
22. Manz W, Amman R, Ludwig W, Vancanneyt M, Schleifer KH: Application of a suite of 16S rRNA-specific probes designed to investigate bacteria of the phylum cytophaga-flavobacter- bacteroides in the natural environment. Microbiology UK 1996; 142: 1097-1106. (Pubitemid 26154919)
23. Sghir A, Gramet G, Suau A, Rochet V, Pochart P, Doré J: Quantification of bacterial groups within human faecal flora by oligonucleotide probe hybridization. Appl Environ Microbiol 2000; 66: 2263-2266. (Pubitemid 30253765)
24. Harmsen HJM, Elfferich P, Schut F, Weling GW: A 16S rRNA-targeted probe for detection of Lactobacilli and Enterococci in faecal samples by fluorescent in situ hybridization. Microb Ecol Health Dis 1999; 11: 3-12.
25. Lay C, Sutren M, Rochet V, Saunier K, Doré J, Rigottier-Gois L: Desing and validation of 16S rRNA probes to enumerate members of the Clostridium leptum subgroup in human faecal microbiota. Environ Microbiol 2005; 7: 933-946.
26. Van Nuenen MH, Venema K, van der Woude JC, Kuipers EJ: The metabolic activity of faecal microbiota from healthy individuals and patients with inflammatory bowel disease. Dig Dis Sci 2004; 49: 485-491. (Pubitemid 38453570)
27. Sepp E, Julge K, Milkasaar M, Björksten B: Intestinal microbiota and immunoglobulin E responses in 5-year-old Estonian children. Clin Exp Allergy 2005; 35: 1141-1146.
28. Sjögren YM, Jenmalm MC, Bötcher MF, Björkstén B, Sverremark-Ekström E: Altered early infant gut microbiota in children developing allergy up to 5 years of age. Clin Exp Allergy 2009; 39: 518-526.
29. Watanabe S, Narisawa Y, Arase S, Okamatsu H, Ikenaga T, Tajiri Y, Kumemura M: Differences in faecal microflora between patients with atopic dermatitis and healthy control subjects. J Allergy Clin Immunol 2003; 111: 587-591. (Pubitemid 36337881)
30. Murray CS, Tannock GW, Simon M-A, Harmsen HJM, Welling GW, Custovic A, Woodcokc A: Faecal microbiota in sensitized wheezy and non-sensitized nonwheezy children: A nested case-control study. Clin Exp Allergy 2005; 35: 741-745. (Pubitemid 40961346)
31. Høverstad T, Midtvedt T, Bøhmer T: Shortchain fatty acids in intestinal content of germ-free mice monocontaminated with E. coli or Cl. Difficile Scand J Gastroenterol 1985; 20: 373-380. (Pubitemid 15089058)
32. Umesaki Y, Setojama H, Matsumoto S, Imaoka A, Itoh K: Differential roles of segmented filamentous bacteria and clostridia in development of the intestinal immune system. Infect Immun 1999; 67: 3504-3511. (Pubitemid 29291522)
33. Wold AE: The hygiene hypothesis revised: Is the rising frequency of allergy due to changes in the intestinal flora? Allergy 1998; 53(46 suppl):20-25. (Pubitemid 28535340)
34. Lin J, Peng L, Itzkowitz S, Holzman IR, Babyatsky MW: Short-chain fatty acid induces intestinal mucosal injury in newborn rats and down-regulates intestinal trefoil factor gene expression in vivo and in vitro. J Pediatr Gastroenterol Nutr 2005; 41: 607-611. (Pubitemid 41579670)
35. Butel MJ, Roland N, Hibert A, Popot F, Favre A, Tessedre AC, Bensaada M, Rimbault A, Szylit O: Clostridial pathogenicity in experimental necrotising enterocolitis in gnobiotic quails and protective role of bifidobacteria. J Med Microbiol 1998; 47: 391-399. (Pubitemid 28191042)
36. Penders J, Stobberingh E, Thijs C, Adams H, Vink C, van Ree R, van den Brandt PA: Molecular firgerprinting of the intestinal microbiota of infants in whom atopic eczema was or was not developing. Clin Exp Allergy 2006; 36: 1602-1608. (Pubitemid 44902938)
37. Suau A, Bonnet R, Sutren M, Godon JJ, Gibson GR, Collins MD, Doré J: Direct analysis of genes encoding 16S rRNA from complex communities reveals many novel molecular species within the human gut. Appl Environ Microbiol 1999; 65: 4799-4807.
38. Alles MS, Hartemink R, Meyboon S, Harryvan JL, van Laere KM, Nagengst FM, Hautvast JG: Effect of transgalactooligosaccharides on the composition of the human intestinal microflora and on putative risk markers for colon cancer. Am J Clin Nutr 1999; 69: 980-991. (Pubitemid 29205074)