Mitochondrial pathway mediates the antileukemic effects of hemidesmus indicus, a promising botanical drug

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Fimognari, Carmela ^a   Lenzi, Monia ^a   Ferruzzi, Lorenzo ^a   Turrini, Eleonora ^a   Scartezzini, Paolo ^a   Poli, Ferruccio ^a   Gotti, Roberto ^a   Guerrini, Alessandra ^b   Carulli, Giovanni ^c   Ottaviano, Virginia ^c   Cantelli Forti, Giorgio ^a   Hrelia, Patrizia ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ADENOSINE DIPHOSPHATE; CALCIUM ION; CASPASE 3; CASPASE 8; CYTARABINE; HEMIDESMUS INDICUS EXTRACT; METHOTREXATE; PROTEIN BAX; PROTEIN BCL 2; TIOGUANINE; CALCIUM; CYTOCHROME C; PLANT EXTRACT;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ANTINEOPLASTIC ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; FEMALE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MALE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN EXPRESSION; APOPTOSIS; CELL CULTURE; CELL CYCLE; CELL STRAIN HL 60; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; FLOW CYTOMETRY; HEMIDESMUS; LEUKEMIA; METABOLISM; MIDDLE AGED; TUMOR CELL LINE;

HEMIDESMUS; HEMIDESMUS INDICUS;

AGED; AGED, 80 AND OVER; APOPTOSIS; CALCIUM; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYTOCHROMES C; FEMALE; FLOW CYTOMETRY; HEMIDESMUS; HL-60 CELLS; HUMANS; LEUKEMIA; MALE; MIDDLE AGED; PLANT EXTRACTS;

EID: 79959624894     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021544     Document Type: Article

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