PARP-1 expression and activity in primary human lung cells

Archives of Toxicology

Volumn 85, Issue 6, 2011, Pages 669-679

  Ahmad, Mohamed ^a   Torky, Abdelrahman ^a   Glahn, Felix ^a   Scheubel, Robert J ^a   Foth, Heidi ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Inter individual variation; Long term cultivation; NHBEC; PARP 1 activity; PARP 1 protein expression; PLC

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; DNA; HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLYMER;

ADULT; AGED; ARTICLE; BRONCHUS MUCOSA; CANCER CELL CULTURE; CHROMATIN; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; EPITHELIUM CELL; EXPLANT; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL; LUNG CARCINOMA; LUNG NON SMALL CELL CANCER; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

AGED; BRONCHI; CELL LINE, TUMOR; CELLS, CULTURED; DNA DAMAGE; DNA REPAIR; FEMALE; HUMANS; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; OXIDANTS; POLY(ADP-RIBOSE) POLYMERASES; REPRODUCIBILITY OF RESULTS; RESPIRATORY MUCOSA; TIME FACTORS;

EID: 79959582654     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-010-0604-y     Document Type: Article

References (36)

1. Adelfalk C, Kontou M, Hirsch-Kauffmann M, Schweiger M (2003) Physical and functional interaction of the Werner syndrome protein with poly-ADP ribosyl transferase. FEBS Lett 554:55-58 (Pubitemid 37324814)
2. Amé JC, Spenlehauer C, de Murcia G (2004) The PARP superfamily. Bioessays 26:882-893 (Pubitemid 39128102)
3. Bizec JC, Klethi J, Mandel P (1989) Regulation of protein adenosine diphosphate ribosylation in bovine lens during aging. Ophthalmic Res 21:175-183 (Pubitemid 19171644)
4. Bouchard VJ, Rouleau M, Poirier GG (2003) PARP-1, a determinant of cell survival in response to DNA damage. Exp Hematol 31:446-454 (Pubitemid 36793950)
5. Bürkle A (2001a) PARP-1: a regulator of genomic stability linked with mammalian longevity. Chembiochem 2:725-728
6. Bürkle A (2001b) Physiology and pathophysiology of poly(ADPribosyl) ation. BioEssays 23:795-806
7. Cepeda V, Fuertes MA, Castilla J, Alonso C, Quevedo C, Soto M, Pérez JM (2006) Poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors in cancer chemotherapy. Recent Patents Anticancer Drug Discov 1:39-53
8. Cherney BW, McBride OW, Chen DF, Alkhatib H, Bhatia K, Hensley P, Smulson ME (1987) cDNA sequence, protein structure, and chromosomal location of the human gene for poly(ADPribose) polymerase. Proc Natl Acad Sci USA 84:8370-8374
9. D'Amours D, Desnoyers S, D'Silva I, Poirier GG (1999) Poly(ADP-ribosyl) ation reactions in the regulation of nuclear functions. Biochem J 342:249-268 (Pubitemid 29425344)
10. Endres M, Scott G, Namura S, Salzman AL, Huang PL, Moskowitz MA, Szabó C (1998) Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion. Neurosci Lett 248:41-44 (Pubitemid 28267098)
11. Faro R, Toyoda Y, McCully JD, Jagtap P, Szabo E, Virag L, Bianchi C, Levitsky S, Szabo C, Sellke FW (2002) Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor. Ann Thorac Surg 73:575-581 (Pubitemid 34117412)
12. Fiorillo C, Pace S, Ponziani V, Nediani C, Perna AM, Liguori P, Cecchi C, Nassi N, Donzelli GP, Formigli L, Nassi P (2002) Poly(ADP-ribose) polymerase activation and cell injury in the course of rat heart heterotopic transplantation. Free Radic Res 36:79-87 (Pubitemid 34498552)
13. Flohr C, Bürkle A, Radicella JP, Epe B (2003) Poly(ADP-ribosyl) ation accelerates DNA repair in a pathway dependent on Cockayne syndrome B protein. Nucl Acids Res 31:5332-5337 (Pubitemid 37441901)
14. Goldfarb RD, Marton A, Szabó E, Virág L, Salzman AL, Glock D, Akhter I, McCarthy R, Parrillo JE, Szabó C (2002) Protective effect of a novel, potent inhibitor of poly(ADPribose) synthetase in a porcine model of severe bacterial sepsis. Crit Care Med 30:974-980
15. Grube K, Bürkle A (1992) Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span. Proc Natl Acad SciUSA89:11759-11763 (Pubitemid 23004723)
16. Jackowski G, Kun E (1981) Age-dependent variation of rates of polyadenosine-diphosphoribose synthesis by cardiocyte nuclei and the lack of correlation of enzymatic activity with macromolecular size distribution of DNA. J Biol Chem 256:3667-3670 (Pubitemid 11089532)
17. Kurosaki T, Ushiro H, Mitsuuchi Y, Suzuki S, Matsuda M, Matsuda Y, Katunuma N, Kangawa K, Matsuo H, Hirose T (1987) Primary structure of human poly(ADP-ribose) synthetase as deduced from cDNA sequence. J Biol Chem 262:15990-15997 (Pubitemid 17165199)
18. Lebel M, Lavoie J, Gaudreault I, Bronsard M, Drouin R (2003) Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice. Am J Pathol 162:1559-1569 (Pubitemid 36512839)
19. Lehmann T, Köhler C, Weidauer E, Taege C, Foth H (2001) Expression of MRP1 and related transporters in human lung cells in culture. Toxicology 5:59-72 (Pubitemid 32830947)
20. Lehmann T, Torky A, Stehfest E, Hofmann S, Foth H (2005) Expression of lung resistance-related protein, LRP, and multi-drug resistance related protein, MRP1. in normal human lung cells in long-term cultures. Arch Toxicol 79:600-609 (Pubitemid 41483268)
21. Li J, Huang CY, Zheng RL, Cui KR, Li JF (2000) Hydrogen peroxide induces apoptosis in human hepatoma cells and alters cell redox status. Cell Biol Int 24:9-23 (Pubitemid 30232369)
22. Meyer-Ficca ML, Meyer RG, Jacobson EL, Jacobson MK (2005) Poly(ADP-ribose) polymerases: managing genome stability. Int J Biochem Cell Biol 37:920-926 (Pubitemid 40311734)
23. Nicoletti VG, Stella AM (2003) Role of PARP under stress conditions: cell death or protection. Neurochem Res 28:187-194 (Pubitemid 36207344)
24. Rosenthal DS, Simbulan-Rosenthal CM, Iyer S, Smith WJ, Ray R, Smulson ME (2000) Calmodulin, poly(ADP-ribose)polymerase and p53 are targets for modulating the effects of sulfur mustard. J Appl Toxicol 20(Suppl 1):S43-S49 (Pubitemid 32600639)
25. Runge DM, Stock TW, Lehmann T, Taege C, Bernauer U, Beer Stolz D, Hofmann S, Foth H (2001) Expression of cytochrome P450 2E1 in normal human bronchial epithelial cells and activation by ethanol in culture. Arch Toxicol 75:335-345 (Pubitemid 32757415)
26. Smith S (2001) The world according to PARP. Trends Biochem Sci 26:174-179
27. Stehfest E, Torky A, Glahn F, Foth H (2006) Non destructive micromethod for MRP1 functional assay in human lung tumor cells. Arch Toxicol 80:125-133 (Pubitemid 43320255)
28. Süsse S, Scholz CJ, Bürkle A, Wiesmüller L (2004) Poly(ADP-ribose) polymerase (PARP-1) and p53 independently function in regulating double strand break repair. Nucl Acids Res 32:669-680
29. Tempera I, Cipriani R, Campagna G, Mancini P, Gatti A, Guidobaldi L, Pantellini F, Mandosi E, Sensi M, Quesada P, Mario UD, D'Erme M, Morano S (2005) Poly(ADP Ribose) Polymerase Activity Is Reduced in Circulating Mononuclear Cells From Type 2 Diabetic Patients. J Cell Physiol 205:387-392 (Pubitemid 41598853)
30. Tong WM, Cortes U, Wang ZQ (2001) Poly(ADP-ribose) polymerase: a guardian angel protecting the genome and suppressing tumorigenesis, Biochim. Biophys Acta 1552:27-37 (Pubitemid 34066626)
31. Torky AR, Stehfest E, Viehweger K, Taege C, Foth H (2005) Immuno-histochemical detection of MRPs in human lung cells in culture. Toxicology 207:437-450 (Pubitemid 40138940)
32. Torky A, Raemisch A, Glahn F, Foth H (2008) Arachidonic acid pathway activates multidrug resistance related protein in cultured human lung cells. Arch Tox 82:323-332 (Pubitemid 351692071)
33. Virág L, Szabó C (2002) The therapeutic potential of poly(ADPribose) polymerase inhibitors. Pharmacol Rev 54:375-429
34. Von Kobbe C, Harrigan JA, May A, Opresko PL, Dawut L, Cheng WH, Bohr VA (2003) Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly (ADP-ribosyl)ation pathway after DNA damage. Mol Cell Biol 23:8601-8613 (Pubitemid 37433365)
35. Watts JA, Grattan RM, Whithlow BS, Kline JA (2001) Actication of poly(ADP-ribose) polymers in severe hemorrhagic shock and resucsication. Am J Physiol Gastrointest Liver Physiol 281:G498-G506
36. Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL (2002) Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297:259-263 (Pubitemid 34761289)