SCOPUS 정보 검색 플랫폼

Volumn 2, Issue 5, 2011, Pages 378-384

Synthesis, in silico screening and bioevaluation of dispiro-cycloalkanones as antitubercular and mycobacterial NAD+-dependent DNA ligase inhibitors

(10) Tripathi, Rama P a Pandey, Jyoti a Kukshal, Vandana c Ajay, Arya a Mishra, Mridul a Dube, Divya c Chopra, Deepti c Dwivedi, R b Chaturvedi, Vinita b Ramachandran, Ravishankar c

a Medicinal and Process Chemistry Division (India)

b Drug Target Discovery and Development Division (India)

c CENTRAL DRUG RESEARCH INSTITUTE (India)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 BIS (PHENYL) DISPIRO[2.1.2.3]DECAN 4 ONE; ALKYLAMINOARYL PHENYL CYCLOPROPYL METHANONE; ALPHA,ALPHA' BIS(BENZYLIDENE)CYCLOHEXANONE; ALPHA,ALPHA' BIS(BENZYLIDENE)CYCLOPENTANONE; ALPHA,ALPHA' BIS(BENZYLIDENE)CYCLOPHEPTANONE; AMINOGLYCOSIDE; BENZYLOXYPHENYL CYCLOPROPYL METHANONE; CYCLOALKANONE; DISPIRO CYCLOALKANONE DERIVATIVE; GLYCOSYL UREIDE; LIGASE INHIBITOR; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PYRIDOCHROMONE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CHEMICAL REACTION; CHEMICAL STRUCTURE; COMPUTER MODEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH INHIBITION; IN VITRO STUDY; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR INTERACTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

MYCOBACTERIUM TUBERCULOSIS;

EID: 79959569642 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c0md00246a Document Type: Article

Times cited : (12)

References (52)

1
- 42949174608
- M. Teresa, G. Lugo and C. A. Bewley, J. Med. Chem., 2008, 51, 2606-2612.
- (2008) J. Med. Chem. , vol.51 , pp. 2606-2612
- Teresa, M.¹ Lugo, G.² Bewley, C.A.³

2
- 32444448306
- Y. Zhang, K. P. Martens and S. Denkin, Drug Discovery Today, 2006, 11, 21-27.
- (2006) Drug Discovery Today , vol.11 , pp. 21-27
- Zhang, Y.¹ Martens, K.P.² Denkin, S.³

3
- 33847681052
- Y. L. Janin, Bioorg. Med. Chem., 2007, 15, 2479-2513.
- (2007) Bioorg. Med. Chem. , vol.15 , pp. 2479-2513
- Janin, Y.L.¹

4
- 4644223350
- K. Duncan and C. E. Barry, Curr. Opin. Microbiol., 2004, 7, 460-465.
- (2004) Curr. Opin. Microbiol. , vol.7 , pp. 460-465
- Duncan, K.¹ Barry, C.E.²

5
- 0011523808
- Global Tuberculosis Control: Surveillance, Planning, and Financing
- World Health Organization. WHO Press: Geneva, Switzerland
- World Health Organization. Global Tuberculosis Control: Surveillance, Planning, and Financing; WHO Report 2008; WHO Press: Geneva, Switzerland.
- (2008) WHO Report

6
- 57449102564
- M. Jassal and W. R. Bishai, Lancet Infect. Dis., 2009, 155, 19-30.
- (2009) Lancet Infect. Dis. , vol.155 , pp. 19-30
- Jassal, M.¹ Bishai, W.R.²

7
- 10444227369
- R. P. Tripathi, N. Tewari, N. Dwivedi and V. K. Tiwari, Med. Res. Rev., 2005, 25, 93-131.
- (2005) Med. Res. Rev. , vol.25 , pp. 93-131
- Tripathi, R.P.¹ Tewari, N.² Dwivedi, N.³ Tiwari, V.K.⁴

8
- 0036150240
- S. H. Gillespie, Antimicrob. Agents Chemother., 2002, 46, 267-274.
- (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 267-274
- Gillespie, S.H.¹

9
- 34447636818
- G. J. Ebrahim, J. Trop. Pediatr., 2007, 53, 147-149.
- (2007) J. Trop. Pediatr. , vol.53 , pp. 147-149
- Ebrahim, G.J.¹

10
- 77149123917
- E. Huitric, P. Verhasselt, A. Koul, K. Andries, S. Hoffner and D. I. Andersson, Antimicrob. Agents Chemother., 2010, 54, 1022-1028.
- (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 1022-1028
- Huitric, E.¹ Verhasselt, P.² Koul, A.³ Andries, K.⁴ Hoffner, S.⁵ Andersson, D.I.⁶

11
- 14044275767
- D. Jones, Nat. Rev. Drug Discovery, 2005, 4, 103-103.
- (2005) Nat. Rev. Drug Discovery , vol.4 , pp. 103-103
- Jones, D.¹

12
- 33750629139
- N. R. Gandhi, A. Moll and A. W. Sturm, Lancet, 2006, 4, 1575-1580.
- (2006) Lancet , vol.4 , pp. 1575-1580
- Gandhi, N.R.¹ Moll, A.² Sturm, A.W.³

13
- 49249114236
- M. C. Raviglione, N. Engl. J. Med., 2008, 7, 636-638.
- (2008) N. Engl. J. Med. , vol.7 , pp. 636-638
- Raviglione, M.C.¹

14
- 12244284440
- (ed.) S. T. Cole, K. D. Eisenach, D. N. McMurray and W. R. Jacobs, Jr., ASM Press, Washington, DC
- Y. Zhang, C. Vilcheze and W. R. Jacobs, in Tuberculosis and the tubercle bacillus, (ed.) S. T. Cole, K. D. Eisenach, D. N. McMurray and W. R. Jacobs, Jr., ASM Press, Washington, DC. 2005, pp. 115-142.
- (2005) Tuberculosis and the Tubercle Bacillus , pp. 115-142
- Zhang, Y.¹ Vilcheze, C.² Jacobs, W.R.³

15
- 34547637078
- M. K. Machala, E. Rychta, A. Brzostek, H. R. Sayer, A. R. Galewicz, R. P. Bowater and J. Dziadek, Antimicrob. Agents Chemother., 2007, 51, 2888-2897.
- (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 2888-2897
- Machala, M.K.¹ Rychta, E.² Brzostek, A.³ Sayer, H.R.⁴ Galewicz, A.R.⁵ Bowater, R.P.⁶ Dziadek, J.⁷

16
- 0016273515
- I. R. Lehman, Science, 1974, 186, 790-797.
- (1974) Science , vol.186 , pp. 790-797
- Lehman, I.R.¹

17
- 77956919579
- ed. P. D. Boyer, Academic Press, New York
- M. J. Engler and C. C. Richardson, in The Enzymes, ed. P. D. Boyer, Academic Press, New York, 1982, vol. 15, pp. 3-29.
- (1982) The Enzymes , vol.15 , pp. 3-29
- Engler, M.J.¹ Richardson, C.C.²

18
- 0034944736
- A. Wilkinson, J. Day and R. Bowater, Mol. Microbiol., 2001, 40, 1241-1248.
- (2001) Mol. Microbiol. , vol.40 , pp. 1241-1248
- Wilkinson, A.¹ Day, J.² Bowater, R.³

19
- 0035965270
- V. Sriskanda, R. W. Moyer and S. J. Shuman, J. Biol. Chem., 2001, 276, 36100-36109.
- (2001) J. Biol. Chem. , vol.276 , pp. 36100-36109
- Sriskanda, V.¹ Moyer, R.W.² Shuman, S.J.³

20
- 0034734323
- D. J. Timson, M. R. Singleton and D. B. Wigley, Mutat. Res., 2000, 460, 301-318.
- (2000) Mutat. Res. , vol.460 , pp. 301-318
- Timson, D.J.¹ Singleton, M.R.² Wigley, D.B.³

21
- 0034327406
- A. J. Doherty and S. W. Suh, Nucleic Acids Res., 2000, 28, 4051-4058.
- (2000) Nucleic Acids Res. , vol.28 , pp. 4051-4058
- Doherty, A.J.¹ Suh, S.W.²

22
- 9644289536
- J. M. Pascal, P. J. O'Brien, A. E. Tomkinson and T. Ellenberger, Nature, 2004, 432, 473-478.
- (2004) Nature , vol.432 , pp. 473-478
- Pascal, J.M.¹ O'Brien, P.J.² Tomkinson, A.E.³ Ellenberger, T.⁴

23
- 4143117765
- K. C. Gajiwala and C. Pinko, Structure, 2004, 12, 1449-1459.
- (2004) Structure , vol.12 , pp. 1449-1459
- Gajiwala, K.C.¹ Pinko, C.²

24
- 0034161570
- J. Y. Lee, C. Chang, H. K. Song, J. Moon, J. K. Yang, H. K. Kim, S. T. Kwon and S. W. Suh, EMBO J., 2000, 19, 1119-1129.
- (2000) EMBO J. , vol.19 , pp. 1119-1129
- Lee, J.Y.¹ Chang, C.² Song, H.K.³ Moon, J.⁴ Yang, J.K.⁵ Kim, H.K.⁶ Kwon, S.T.⁷ Suh, S.W.⁸

25
- 2442717521
- C. Gong, A. Martins, P. Bongiorno, M. Glickman and S. Shuman, J. Biol. Chem., 2004, 279, 20594-20606.
- (2004) J. Biol. Chem. , vol.279 , pp. 20594-20606
- Gong, C.¹ Martins, A.² Bongiorno, P.³ Glickman, M.⁴ Shuman, S.⁵

26
- 0037624901
- A. Wilkinson, H. Sayer, D. Bullard, A. Smith, J. Day, T. Kieser and R. P. Bowater, Proteins: Struct., Funct., Bioinf., 2003, 51, 321-326.
- (2003) Proteins: Struct., Funct., Bioinf. , vol.51 , pp. 321-326
- Wilkinson, A.¹ Sayer, H.² Bullard, D.³ Smith, A.⁴ Day, J.⁵ Kieser, T.⁶ Bowater, R.P.⁷

27
- 0018363205
- J. J. Dermody, G. T. Robinson and R. Sternglanz, J. Bacteriol., 1979, 139, 701-704.
- (1979) J. Bacteriol. , vol.139 , pp. 701-704
- Dermody, J.J.¹ Robinson, G.T.² Sternglanz, R.³

28
- 0035040993
- F. S. Kaczmarek, R. P. Zaniewski, T. D. Gootz, D. E. Danley, M. N. Mansour, M. Griffor, A. V. Kamath, M. Cronan, J. Mueller, D. Sun, P. K. Martin, B. Benton, L. McDowell, D. Biek and M. B. Schmid, J. Bacteriol., 2001, 183, 3016-3024.
- (2001) J. Bacteriol. , vol.183 , pp. 3016-3024
- Kaczmarek, F.S.¹ Zaniewski, R.P.² Gootz, T.D.³ Danley, D.E.⁴ Mansour, M.N.⁵ Griffor, M.⁶ Kamath, A.V.⁷ Cronan, M.⁸ Mueller, J.⁹ Sun, D.¹⁰ Martin, P.K.¹¹ Benton, B.¹² McDowell, L.¹³ Biek, D.¹⁴ Schmid, M.B.¹⁵

29
- 0034424041
- M. A. Petit and S. D. Ehrlich, Nucleic Acids Res., 2000, 28, 4642-4648.
- (2000) Nucleic Acids Res. , vol.28 , pp. 4642-4648
- Petit, M.A.¹ Ehrlich, S.D.²

30
- 0345701347
- C. M. Sassetti, D. H. Boyd and E. J. Rubin, Mol. Microbiol., 2003, 48, 77-84.
- (2003) Mol. Microbiol. , vol.48 , pp. 77-84
- Sassetti, C.M.¹ Boyd, D.H.² Rubin, E.J.³

31
- 0032755479
- G. Ciarrocchi, D. G. MacPhee, L. W. Deady and L. Tilley, Antimicrob. Agents Chemother., 1999, 43, 2766-2772.
- (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 2766-2772
- Ciarrocchi, G.¹ MacPhee, D.G.² Deady, L.W.³ Tilley, L.⁴

32
- 0141994876
- H. Brotz-Oesterhelt, I. Knezevic, S. Bartel, T. Lampe, U. Warnecke-Eberz, K. Ziegelbauer, D. Habich and H. Labischiinski, J. Biol. Chem., 2003, 278, 39435-39442.
- (2003) J. Biol. Chem. , vol.278 , pp. 39435-39442
- Brotz-Oesterhelt, H.¹ Knezevic, I.² Bartel, S.³ Lampe, T.⁴ Warnecke-Eberz, U.⁵ Ziegelbauer, K.⁶ Habich, D.⁷ Labischiinski, H.⁸

33
- 24044548989
- S. K. Srivastava, R. P. Tripathi and R. Ramachandran, J. Biol. Chem., 2005, 280, 30273-30281.
- (2005) J. Biol. Chem. , vol.280 , pp. 30273-30281
- Srivastava, S.K.¹ Tripathi, R.P.² Ramachandran, R.³

34
- 31344436112
- S. K. Srivastava, D. Dube, N. Tewari, N. Dwivedi, R. P. Tripathi and R. Ramachandran, Nucleic Acids Res., 2005, 33, 7090-7101.
- (2005) Nucleic Acids Res. , vol.33 , pp. 7090-7101
- Srivastava, S.K.¹ Dube, D.² Tewari, N.³ Dwivedi, N.⁴ Tripathi, R.P.⁵ Ramachandran, R.⁶

35
- 0042835657
- D. Katiyar, V. K. Tiwari, R. P. Tripathi, A. Srivastava, V. Chaturvedi, R. Srivastava and B. S. Srivastava, Bioorg. Med. Chem., 2003, 11, 4369-4375.
- (2003) Bioorg. Med. Chem. , vol.11 , pp. 4369-4375
- Katiyar, D.¹ Tiwari, V.K.² Tripathi, R.P.³ Srivastava, A.⁴ Chaturvedi, V.⁵ Srivastava, R.⁶ Srivastava, B.S.⁷

36
- 0346099288
- N. Tewari, V. K. Tiwari, R. P. Tripathi, V. Chaturvedi, A. Srivastava, R. Srivastava, P. K. Shukla, A. K. Chaturvedi, A. Gaikwad, S. Sinha and B. S. Srivastava, Bioorg. Med. Chem. Lett., 2004, 14, 329-332.
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 329-332
- Tewari, N.¹ Tiwari, V.K.² Tripathi, R.P.³ Chaturvedi, V.⁴ Srivastava, A.⁵ Srivastava, R.⁶ Shukla, P.K.⁷ Chaturvedi, A.K.⁸ Gaikwad, A.⁹ Sinha, S.¹⁰ Srivastava, B.S.¹¹

37
- 0345714650
- R. C. Mishra, R. Tripathi, D. Katiyar, N. Tewari, D. Singh and R. P. Tripathi, Bioorg. Med. Chem., 2003, 11, 5363-5374.
- (2003) Bioorg. Med. Chem. , vol.11 , pp. 5363-5374
- Mishra, R.C.¹ Tripathi, R.² Katiyar, D.³ Tewari, N.⁴ Singh, D.⁵ Tripathi, R.P.⁶

38
- 0037871689
- N. Tewari, V. K. Tiwari, R. C. Mishra, R. P. Tripathi, A. K. Srivastava, R. Ahmad, R. Srivastava and B. S. Srivastava, Bioorg. Med. Chem., 2003, 11, 2911-2922.
- (2003) Bioorg. Med. Chem. , vol.11 , pp. 2911-2922
- Tewari, N.¹ Tiwari, V.K.² Mishra, R.C.³ Tripathi, R.P.⁴ Srivastava, A.K.⁵ Ahmad, R.⁶ Srivastava, R.⁷ Srivastava, B.S.⁸

39
- 23944523861
- N. Tewari, V. K. Tiwari, D. Katiyar, N. Saxena, S. Sinha, A. Gaikwad, A. Srivastava, V. Chaturvedi, Y. K. Manju, R. Srivastava and B. S. Srivastava, Bioorg. Med. Chem., 2005, 13, 5668-5679.
- (2005) Bioorg. Med. Chem. , vol.13 , pp. 5668-5679
- Tewari, N.¹ Tiwari, V.K.² Katiyar, D.³ Saxena, N.⁴ Sinha, S.⁵ Gaikwad, A.⁶ Srivastava, A.⁷ Chaturvedi, V.⁸ Manju, Y.K.⁹ Srivastava, R.¹⁰ Srivastava, B.S.¹¹

40
- 61349152974
- N. Singh, J. Pandey, A. Yadav, V. Chaturvedi, S. Bhatnagar, A. Gaikwad, S. Sinha, A. Kumar, P. K. Shukla and R. P. Tripathi, Eur. J. Med. Chem., 2009, 44, 1705-1709.
- (2009) Eur. J. Med. Chem. , vol.44 , pp. 1705-1709
- Singh, N.¹ Pandey, J.² Yadav, A.³ Chaturvedi, V.⁴ Bhatnagar, S.⁵ Gaikwad, A.⁶ Sinha, S.⁷ Kumar, A.⁸ Shukla, P.K.⁹ Tripathi, R.P.¹⁰

41
- 24344447290
- N. Dwivedi, N. Tewari, V. K. Tiwari, V. Chaturvedi, Y. K. Manju, A. Srivastava, A. Giakwad, S. Sinha and R. P. Tripathi, Bioorg. Med. Chem. Lett., 2005, 15, 4526-4530.
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 4526-4530
- Dwivedi, N.¹ Tewari, N.² Tiwari, V.K.³ Chaturvedi, V.⁴ Manju, Y.K.⁵ Srivastava, A.⁶ Giakwad, A.⁷ Sinha, S.⁸ Tripathi, R.P.⁹

42
- 78249258717
- A. Ajay, V. Singh, S. Singh, S. Pandey, S. Gunjan, D. Dubey, S. K. Sinha, B. N. Singh, V. Chaturvedi, R. Tripathi, R. Ramchandran and R. P. Tripathi, Bioorg. Med. Chem., 2010, 18, 8289-8301.
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 8289-8301
- Ajay, A.¹ Singh, V.² Singh, S.³ Pandey, S.⁴ Gunjan, S.⁵ Dubey, D.⁶ Sinha, S.K.⁷ Singh, B.N.⁸ Chaturvedi, V.⁹ Tripathi, R.¹⁰ Ramchandran, R.¹¹ Tripathi, R.P.¹²

43
- 33947485009
- E. J. Corey and M. Chaykovsky, J. Am. Chem. Soc., 1965, 87, 1353-1364.
- (1965) J. Am. Chem. Soc. , vol.87 , pp. 1353-1364
- Corey, E.J.¹ Chaykovsky, M.²

44
- 3042702898
- M. H. Abraham and Y. H. Zhao, J. Org. Chem., 2004, 69, 4677-4685.
- (2004) J. Org. Chem. , vol.69 , pp. 4677-4685
- Abraham, M.H.¹ Zhao, Y.H.²

45
- 0037471473
- S. Chandrasekhar, C. Narasihmulu, V. Jagadeshwar and K. V. Reddy, Tetrahedron Lett., 2003, 44, 3629-3630.
- (2003) Tetrahedron Lett. , vol.44 , pp. 3629-3630
- Chandrasekhar, S.¹ Narasihmulu, C.² Jagadeshwar, V.³ Reddy, K.V.⁴

46
- 33947238021
- R. J. Paxton and R. J. K. Taylor, Synlett, 2007, 4, 633-637.
- (2007) Synlett , vol.4 , pp. 633-637
- Paxton, R.J.¹ Taylor, R.J.K.²

47
- 34547098110
- A. Hartikka and P. I. Arvidsson, J. Org. Chem., 2007, 72, 5874-877.
- (2007) J. Org. Chem. , vol.72 , pp. 5874-5877
- Hartikka, A.¹ Arvidsson, P.I.²

48
- 0026034493
- H. Saito, H. Tomioka, K. Sato, M. Emori, T. Yamane, K. Yamashita, K. Hosol and T. Hidaka, Antimicrob. Agents Chemother., 1991, 35, 542-547.
- (1991) Antimicrob. Agents Chemother. , vol.35 , pp. 542-547
- Saito, H.¹ Tomioka, H.² Sato, K.³ Emori, M.⁴ Yamane, T.⁵ Yamashita, K.⁶ Hosol, K.⁷ Hidaka, T.⁸

49
- 79959547387
- San Diego, CA, Accelrys Inc.
- ACCELRYS ver., 11. San Diego, CA, Accelrys Inc., 2000, pp. 92121-92152.
- (2000) Accelrys Ver., 11 , pp. 92121-92152

50
- 11644261806
- G. M. Morris, D. S. Goodsell, R. S. Halliday, R. Huey and W. E. Hart, J. Comput. Chem., 1998, 19, 1639-1662.
- (1998) J. Comput. Chem. , vol.19 , pp. 1639-1662
- Morris, G.M.¹ Goodsell, D.S.² Halliday, R.S.³ Huey, R.⁴ Hart, W.E.⁵

51
- 0014202608
- J. B. Le-Pecq and C. Paoletti, J. Mol. Biol., 1967, 27, 87.
- (1967) J. Mol. Biol. , vol.27 , pp. 87
- Le-Pecq, J.B.¹ Paoletti, C.²

52
- 24044548989
- S. K. Srivastava, R. P. Tripathi and R. Ravishankar, J. Biol. Chem., 2005, 280, 30273-30281.
- (2005) J. Biol. Chem. , vol.280 , pp. 30273-30281
- Srivastava, S.K.¹ Tripathi, R.P.² Ravishankar, R.³

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