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Volumn 16, Issue 7, 2011, Pages 2622-2641

Applications of proteomics in cartilage biology and osteoarthritis research

Author keywords

Articular cartilage; Biomarker; Channelome; Chondrocyte; Collagen; Extracellular matrix; Glycome; Membrane protein; OA; Osteoarthritis; Proteoglycan; Proteome; Review; Synovial joint; Synoviocyte; Synovium

Indexed keywords

BIOLOGICAL MARKER;

EID: 79959566020     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3876     Document Type: Article
Times cited : (14)

References (159)
  • 1
    • 3342964033 scopus 로고    scopus 로고
    • Biomarker discovery and validation: Technologies and integrative approaches
    • DOI 10.1016/j.tibtech.2004.06.005, PII S0167779904001702
    • SE Ilyin, SM Belkowski and CR Plata-Salaman: Biomarker discovery and validation: technologies and integrative approaches. Trends Biotechnol, 22(8), 411-6 (2004) (Pubitemid 38993225)
    • (2004) Trends in Biotechnology , vol.22 , Issue.8 , pp. 411-416
    • Ilyin, S.E.1    Belkowski, S.M.2    Plata-Salaman, C.R.3
  • 2
    • 0031602467 scopus 로고    scopus 로고
    • Articular cartilage: Degeneration and osteoarthritis, repair, regeneration, and transplantation
    • JA Buckwalter and HJ Mankin: Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Instr Course Lect, 47, 487-504 (1998)
    • (1998) Instr Course Lect , vol.47 , pp. 487-504
    • Buckwalter, J.A.1    Mankin, H.J.2
  • 3
    • 1642555916 scopus 로고    scopus 로고
    • Post-genomic applications of tissue microarrays: Basic research, prognostic oncology, clinical genomics and drug discovery
    • A Mobasheri, R Airley, CS Foster, G Schulze-Tanzil and M Shakibaei: Post-genomic applications of tissue microarrays: basic research, prognostic oncology, clinical genomics and drug discovery. Histol Histopathol, 19(1), 325-35 (2004) (Pubitemid 38111276)
    • (2004) Histology and Histopathology , vol.19 , Issue.1 , pp. 325-335
    • Mobasheri, A.1    Airley, R.2    Foster, C.S.3    Schulze-Tanzil, G.4    Shakibaei, M.5
  • 4
    • 0041828558 scopus 로고    scopus 로고
    • Biomarkers in osteoarthritis
    • DOI 10.1097/00002281-200309000-00020
    • P Garnero and PD Delmas: Biomarkers in osteoarthritis. Curr Opin Rheumatol, 15(5), 641-6 (2003) (Pubitemid 37041406)
    • (2003) Current Opinion in Rheumatology , vol.15 , Issue.5 , pp. 641-646
    • Garnero, P.1    Delmas, P.D.2
  • 5
    • 0025970886 scopus 로고
    • Study of 500 patients with limb joint osteoarthritis. I. Analysis by age, sex, and distribution of symptomatic joint sites
    • J Cushnaghan and P Dieppe: Study of 500 patients with limb joint osteoarthritis. I. Analysis by age, sex, and distribution of symptomatic joint sites. Ann Rheum Dis, 50(1), 8-13 (1991)
    • (1991) Ann Rheum Dis , vol.50 , Issue.1 , pp. 8-13
    • Cushnaghan, J.1    Dieppe, P.2
  • 6
    • 5444247066 scopus 로고    scopus 로고
    • Risk factors for osteoarthritis: Understanding joint vulnerability
    • DOI 10.1097/01.blo.0000144971.12731.a2
    • DT Felson: Risk factors for osteoarthritis: understanding joint vulnerability. Clin Orthop Relat Res(427 Suppl), S16- 21 (2004) (Pubitemid 39362795)
    • (2004) Clinical Orthopaedics and Related Research , Issue.427 SUPPL.
    • Felson, D.T.1
  • 9
    • 77954029991 scopus 로고    scopus 로고
    • Identification, validation and qualification of biomarkers for osteoarthritis in humans and companion animals: Mission for the next decade
    • A Mobasheri and Y Henrotin: Identification, validation and qualification of biomarkers for osteoarthritis in humans and companion animals: mission for the next decade. Vet J, 185(2), 95-7 (2010)
    • (2010) Vet J , vol.185 , Issue.2 , pp. 95-97
    • Mobasheri, A.1    Henrotin, Y.2
  • 10
    • 33750634123 scopus 로고    scopus 로고
    • The proteomic search for diagnostic biomarkers: Lost in translation?
    • DOI 10.1074/mcp.R600001-MCP200
    • W Zolg: The proteomic search for diagnostic biomarkers: lost in translation? Mol Cell Proteomics, 5(10), 1720-6 (2006) (Pubitemid 44688184)
    • (2006) Molecular and Cellular Proteomics , vol.5 , Issue.10 , pp. 1720-1726
    • Zolg, W.1
  • 12
    • 21844453211 scopus 로고    scopus 로고
    • New frontiers in proteomics research: A perspective
    • DOI 10.1016/j.ijpharm.2005.04.010, PII S0378517305002267
    • V Dhingra, M Gupta, T Andacht and ZF Fu: New frontiers in proteomics research: A perspective. International Journal of Pharmaceutics, 299(1-2), 1-18 (2005) (Pubitemid 40962401)
    • (2005) International Journal of Pharmaceutics , vol.299 , Issue.1-2 , pp. 1-18
    • Dhingra, V.1    Gupta, M.2    Andacht, T.3    Fu, Z.F.4
  • 13
    • 0031608434 scopus 로고    scopus 로고
    • Articular cartilage: Tissue design and chondrocyte-matrix interactions
    • JA Buckwalter and HJ Mankin: Articular cartilage: tissue design and chondrocyte-matrix interactions. Instr Course Lect, 47, 477-86 (1998)
    • (1998) Instr Course Lect , vol.47 , pp. 477-486
    • Buckwalter, J.A.1    Mankin, H.J.2
  • 14
    • 0029583775 scopus 로고
    • The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules
    • H Muir: The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules. Bioessays, 17(12), 1039-48 (1995) (Pubitemid 3009484)
    • (1995) BioEssays , vol.17 , Issue.12 , pp. 1039-1048
    • Muir, H.1
  • 15
    • 27144483873 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: Putative molecular components of the oxygen and glucose sensing apparatus in articular chondrocytes
    • A Mobasheri, S Richardson, R Mobasheri, M Shakibaei and JA Hoyland: Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: putative molecular components of the oxygen and glucose sensing apparatus in articular chondrocytes. Histol Histopathol, 20(4), 1327-38 (2005) (Pubitemid 41489176)
    • (2005) Histology and Histopathology , vol.20 , Issue.4 , pp. 1327-1338
    • Mobasheri, A.1    Richardson, S.2    Mobasheri, R.3    Shakibaei, M.4    Hoyland, J.A.5
  • 16
    • 58149170369 scopus 로고    scopus 로고
    • Facilitative glucose transporters in articular chondrocytes. Expression, distribution and functional regulation of GLUT isoforms by hypoxia, hypoxia mimetics, growth factors and pro-inflammatory cytokines
    • 1 p following vi
    • A Mobasheri, CA Bondy, K Moley, AF Mendes, SC Rosa, SM Richardson, JA Hoyland, R Barrett-Jolley and M Shakibaei: Facilitative glucose transporters in articular chondrocytes. Expression, distribution and functional regulation of GLUT isoforms by hypoxia, hypoxia mimetics, growth factors and pro-inflammatory cytokines. Adv Anat Embryol Cell Biol, 200, 1 p following vi, 1-84 (2008)
    • (2008) Adv Anat Embryol Cell Biol , vol.200 , pp. 1-84
    • Mobasheri, A.1    Bondy, C.A.2    Moley, K.3    Mendes, A.F.4    Rosa, S.C.5    Richardson, S.M.6    Hoyland, J.A.7    Barrett-Jolley, R.8    Shakibaei, M.9
  • 18
    • 24344480012 scopus 로고    scopus 로고
    • Hypoxia and HIF-1 alpha in chondrogenesis
    • E Schipani: Hypoxia and HIF-1 alpha in chondrogenesis. Semin Cell Dev Biol, 16(4-5), 539-46 (2005)
    • (2005) Semin Cell Dev Biol , vol.16 , Issue.4-5 , pp. 539-546
    • Schipani, E.1
  • 19
    • 33744764250 scopus 로고    scopus 로고
    • Hypoxia and HIF-1alpha in chondrogenesis
    • E Schipani: Hypoxia and HIF-1alpha in chondrogenesis. Ann N Y Acad Sci, 1068, 66-73 (2006)
    • (2006) Ann N y Acad Sci , vol.1068 , pp. 66-73
    • Schipani, E.1
  • 20
    • 70149094866 scopus 로고    scopus 로고
    • Hypoxia. HIF-mediated articular chondrocyte function: Prospects for cartilage repair
    • CL Murphy, BL Thoms, RJ Vaghjiani and JE Lafont: Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair. Arthritis Res Ther, 11(1), 213 (2009)
    • (2009) Arthritis Res Ther , vol.11 , Issue.1 , pp. 213
    • Murphy, C.L.1    Thoms, B.L.2    Vaghjiani, R.J.3    Lafont, J.E.4
  • 21
    • 77749302262 scopus 로고    scopus 로고
    • Lack of oxygen in articular cartilage: Consequences for chondrocyte biology
    • JE Lafont: Lack of oxygen in articular cartilage: consequences for chondrocyte biology. Int J Exp Pathol, 91(2), 99-106 (2010)
    • (2010) Int J Exp Pathol , vol.91 , Issue.2 , pp. 99-106
    • Lafont, J.E.1
  • 22
    • 5444243560 scopus 로고    scopus 로고
    • Collagens and cartilage matrix homeostasis
    • DOI 10.1097/01.blo.0000144855.48640.b9
    • DR Eyre: Collagens and cartilage matrix homeostasis. Clin Orthop Relat Res(427 Suppl), S118-22 (2004) (Pubitemid 39362810)
    • (2004) Clinical Orthopaedics and Related Research , Issue.427 SUPPL.
    • Eyre, D.R.1
  • 25
    • 0028302391 scopus 로고
    • Cartilage proteoglycans: Structure and potential functions
    • DOI 10.1002/jemt.1070280505
    • PJ Roughley and ER Lee: Cartilage proteoglycans: structure and potential functions. Microsc Res Tech, 28(5), 385-97 (1994) (Pubitemid 24222670)
    • (1994) Microscopy Research and Technique , vol.28 , Issue.5 , pp. 385-397
    • Roughley, P.J.1    Lee, E.R.2
  • 26
    • 27144473960 scopus 로고    scopus 로고
    • Aggrecan, aging and assembly in articular cartilage
    • DOI 10.1007/s00018-005-5217-x
    • J Dudhia: Aggrecan, aging and assembly in articular cartilage. Cell Mol Life Sci, 62(19-20), 2241-56 (2005) (Pubitemid 41500541)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.19-20 , pp. 2241-2256
    • Dudhia, J.1
  • 29
    • 0015738354 scopus 로고
    • Environmental enhancement of in vitro chondrogenesis. IV. Stimulation of somite chondrogenesis by exogenous chondromucoprotein
    • RA Kosher, JW Lash and RR Minor: Environmental enhancement of in vitro chondrogenesis. IV. Stimulation of somite chondrogenesis by exogenous chondromucoprotein. Dev Biol, 35(2), 210-20 (1973)
    • (1973) Dev Biol , vol.35 , Issue.2 , pp. 210-220
    • Kosher, R.A.1    Lash, J.W.2    Minor, R.R.3
  • 30
    • 0016726117 scopus 로고
    • Stimulation of in vitro somite chondrogenesis by procollagen and collagen
    • RA Kosher and RL Church: Stimulation of in vitro somite chondrogenesis by procollagen and collagen. Nature, 258(5533), 327-30 (1975)
    • (1975) Nature , vol.258 , Issue.5533 , pp. 327-3230
    • Kosher, R.A.1    Church, R.L.2
  • 31
    • 0017723046 scopus 로고
    • Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture
    • K von der Mark, V Gauss, H von der Mark and P Muller: Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature, 267(5611), 531-2 (1977) (Pubitemid 8098481)
    • (1977) Nature , vol.267 , Issue.5611 , pp. 531-532
    • Von Der Mark, K.1    Gauss, V.2    Von Der Mark, H.3    Mueller, P.4
  • 32
    • 0020344980 scopus 로고
    • The role of chondronectin and cartilage proteoglycan in the attachment of chondrocytes to collagen
    • AT Hewitt, HH Varner, MH Silver and GR Martin: The role of chondronectin and cartilage proteoglycan in the attachment of chondrocytes to collagen. Prog Clin Biol Res, 110 Pt B, 25-33 (1982)
    • (1982) Prog Clin Biol Res , vol.110 , Issue.PART B , pp. 25-33
    • Hewitt, A.T.1    Varner, H.H.2    Silver, M.H.3    Martin, G.R.4
  • 33
    • 0024422641 scopus 로고
    • Chondrocyte-matrix interactions. Attachment to proteins isolated from cartilage
    • DOI 10.1016/0014-4827(89)90376-5
    • Y Sommarin, T Larsson and D Heinegard: Chondrocyte-matrix interactions. Attachment to proteins isolated from cartilage. Exp Cell Res, 184(1), 181-92 (1989) (Pubitemid 19233398)
    • (1989) Experimental Cell Research , vol.184 , Issue.1 , pp. 181-192
    • Sommarin, Y.1    Larsson, T.2    Heinegard, D.3
  • 34
    • 0026560854 scopus 로고
    • Tripeptide RGD-dependent adhesion of articular chondrocytes to synovial fibroblasts
    • A Ramachandrula, K Tiku and ML Tiku: Tripeptide RGD-dependent adhesion of articular chondrocytes to synovial fibroblasts. J Cell Sci, 101 ( Pt 4), 859-71 (1992)
    • (1992) J Cell Sci , vol.101 , Issue.PART 4 , pp. 859-871
    • Ramachandrula, A.1    Tiku, K.2    Tiku, M.L.3
  • 35
    • 0028335948 scopus 로고
    • Anchorage dependence, integrins, and apoptosis
    • DOI 10.1016/0092-8674(94)90209-7
    • E Ruoslahti and JC Reed: Anchorage dependence, integrins, and apoptosis. Cell, 77(4), 477-8 (1994) (Pubitemid 24153987)
    • (1994) Cell , vol.77 , Issue.4 , pp. 477-478
    • Ruoslahti, E.1    Reed, J.C.2
  • 37
    • 0027225936 scopus 로고
    • Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus
    • FA Gonzalez, A Seth, DL Raden, DS Bowman, FS Fay and RJ Davis: Serum-induced translocation of mitogenactivated protein kinase to the cell surface ruffling membrane and the nucleus. J Cell Biol, 122(5), 1089-101 (1993) (Pubitemid 23254176)
    • (1993) Journal of Cell Biology , vol.122 , Issue.5 , pp. 1089-1101
    • Gonzalez, F.A.1    Seth, A.2    Raden, D.L.3    Bowman, D.S.4    Fay, F.S.5    Davis, R.J.6
  • 39
    • 0024575180 scopus 로고
    • Effect of somatomedin-C/Insulin-like growth factor I and growth hormone on cultured growth plate and articular chondrocytes
    • SB Trippel, MT Corvol, MF Dumontier, R Rappaport, HH Hung and HJ Mankin: Effect of somatomedin-C/insulin-like growth factor I and growth hormone on cultured growth plate and articular chondrocytes. Pediatr Res, 25(1), 76-82 (1989) (Pubitemid 19027882)
    • (1989) Pediatric Research , vol.25 , Issue.1 , pp. 76-82
    • Trippel, S.B.1    Corvol, M.T.2    Dumontier, M.F.3    Rappaport, R.4    Hung, H.H.5    Mankin, H.J.6
  • 40
    • 0026833816 scopus 로고
    • Expression and regulation of IGF-I in cartilage and skeletal muscle
    • J Isgaard: Expression and regulation of IGF-I in cartilage and skeletal muscle. Growth Regul, 2(1), 16-22 (1992)
    • (1992) Growth Regul , vol.2 , Issue.1 , pp. 16-22
    • Isgaard, J.1
  • 41
    • 0028331261 scopus 로고
    • Differential effects of insulin-like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytes in vivo
    • EB Hunziker, J Wagner and J Zapf: Differential effects of insulin-like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytes in vivo. J Clin Invest, 93(3), 1078-86 (1994) (Pubitemid 24087160)
    • (1994) Journal of Clinical Investigation , vol.93 , Issue.3 , pp. 1078-1086
    • Hunziker, E.B.1    Wagner, J.2    Zapf, J.3
  • 42
    • 0028302411 scopus 로고
    • Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants
    • DOI 10.1006/abbi.1994.1020
    • RL Sah, AC Chen, AJ Grodzinsky and SB Trippel: Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants. Arch Biochem Biophys, 308(1), 137-47 (1994) (Pubitemid 24172615)
    • (1994) Archives of Biochemistry and Biophysics , vol.308 , Issue.1 , pp. 137-147
    • Sah, R.L.1    Chen, A.C.2    Grodzinsky, A.J.3    Trippel, S.B.4
  • 43
    • 0031043472 scopus 로고    scopus 로고
    • Growth factor regulation of chondrocyte integrins: Differential effects of insulin-like growth factor 1 and transforming growth factor β on α1β1 integrin expression and chondrocyte adhesion to type VI collagen
    • DOI 10.1002/art.1780400211
    • RF Loeser: Growth factor regulation of chondrocyte integrins. Differential effects of insulin-like growth factor 1 and transforming growth factor beta on alpha 1 beta 1 integrin expression and chondrocyte adhesion to type VI collagen. Arthritis Rheum, 40(2), 270-6 (1997) (Pubitemid 27114090)
    • (1997) Arthritis and Rheumatism , vol.40 , Issue.2 , pp. 270-276
    • Loeser, R.F.1
  • 44
    • 0030482992 scopus 로고    scopus 로고
    • Increased degradation and altered tissue distribution of cartilage oligomeric matrix protein in human rheumatoid and osteoarthritic cartilage
    • DOI 10.1002/jor.1100140615
    • PE Di Cesare, CS Carlson, ES Stolerman, N Hauser, H Tulli and M Paulsson: Increased degradation and altered tissue distribution of cartilage oligomeric matrix protein in human rheumatoid and osteoarthritic cartilage. J Orthop Res, 14(6), 946-55 (1996) (Pubitemid 27044464)
    • (1996) Journal of Orthopaedic Research , vol.14 , Issue.6 , pp. 946-955
    • Di Cesare, P.E.1    Carlson, C.S.2    Stolerman, E.S.3    Hauser, N.4    Tulli, H.5    Paulsson, M.6
  • 45
    • 0030957433 scopus 로고    scopus 로고
    • Cartilage fibronectin isoforms: In search of functions for a special population of matrix glycoproteins
    • DOI 10.1016/S0945-053X(97)90018-4
    • N Burton-Wurster, G Lust and JN Macleod: Cartilage fibronectin isoforms: in search of functions for a special population of matrix glycoproteins. Matrix Biol, 15(7), 441-54 (1997) (Pubitemid 27135732)
    • (1997) Matrix Biology , vol.15 , Issue.7 , pp. 441-454
    • Burton-Wurster, N.1    Lust, G.2    MacLeod, J.N.3
  • 46
    • 0037363487 scopus 로고    scopus 로고
    • Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen
    • S Oesser and J Seifert: Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen. Cell Tissue Res, 311(3), 393-9 (2003) (Pubitemid 36459678)
    • (2003) Cell and Tissue Research , vol.311 , Issue.3 , pp. 393-399
    • Oesser, S.1    Seifert, J.2
  • 47
    • 0036182992 scopus 로고    scopus 로고
    • Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes
    • DOI 10.1006/cbir.2001.0826
    • A Mobasheri, SD Carter, P Martin-Vasallo and M Shakibaei: Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes. Cell Biol Int, 26(1), 1-18 (2002) (Pubitemid 34174402)
    • (2002) Cell Biology International , vol.26 , Issue.1 , pp. 1-18
    • Mobasheri, A.1    Carter, S.D.2    Martin-Vasallo, P.3    Shakibaei, M.4
  • 48
    • 2942624012 scopus 로고    scopus 로고
    • Integrin-dependent signal cascades in chondrocyte mechanotransduction
    • SJ Millward-Sadler and DM Salter: Integrin-dependent signal cascades in chondrocyte mechanotransduction. Ann Biomed Eng, 32(3), 435-46 (2004)
    • (2004) Ann Biomed Eng , vol.32 , Issue.3 , pp. 435-446
    • Millward-Sadler, S.J.1    Salter, D.M.2
  • 50
    • 0026632746 scopus 로고
    • Effects of physical activity on some components of the skeletal system
    • N Maffulli and JB King: Effects of physical activity on some components of the skeletal system. Sports Med, 13(6), 393-407 (1992)
    • (1992) Sports Med , vol.13 , Issue.6 , pp. 393-407
    • Maffulli, N.1    King, J.B.2
  • 54
    • 0035157124 scopus 로고    scopus 로고
    • Age-related changes in the morphology and deformational behavior of knee joint cartilage
    • DOI 10.1002/1529-0131(200111)44:1 1<2556::AID-ART436>3.0.CO;2-U
    • M Hudelmaier, C Glaser, J Hohe, KH Englmeier, M Reiser, R Putz and F Eckstein: Age-related changes in the morphology and deformational behavior of knee joint cartilage. Arthritis Rheum, 44(11), 2556-61 (2001) (Pubitemid 33049334)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.11 , pp. 2556-2561
    • Hudelmaier, M.1    Glaser, C.2    Hohe, J.3    Englmeier, K.-H.4    Reiser, M.5    Putz, R.6    Eckstein, F.7
  • 55
    • 0035118121 scopus 로고    scopus 로고
    • In vivo morphometry and functional analysis of human articular cartilage with quantitative magnetic resonance imaging - From image to data, from data to theory
    • DOI 10.1007/s004290000154
    • F Eckstein, M Reiser, KH Englmeier and R Putz: In vivo morphometry and functional analysis of human articular cartilage with quantitative magnetic resonance imaging-from image to data, from data to theory. Anat Embryol (Berl), 203(3), 147-73 (2001) (Pubitemid 32186473)
    • (2001) Anatomy and Embryology , vol.203 , Issue.3 , pp. 147-173
    • Eckstein, F.1    Reiser, M.2    Englmeier, K.-H.3    Putz, R.4
  • 56
    • 0028341007 scopus 로고
    • The joint capsule: Structure, composition, ageing and disease
    • JR Ralphs and M Benjamin: The joint capsule: structure, composition, ageing and disease. J Anat, 184 ( Pt 3), 503-9 (1994) (Pubitemid 24186472)
    • (1994) Journal of Anatomy , vol.184 , Issue.3 , pp. 503-509
    • Ralphs, J.R.1    Benjamin, M.2
  • 58
    • 0033569188 scopus 로고    scopus 로고
    • An introduction to the pathophysiology of osteoarthritis
    • AR Poole: An introduction to the pathophysiology of osteoarthritis. Front Biosci, 4, D662-70 (1999)
    • (1999) Front Biosci , vol.4
    • Poole, A.R.1
  • 59
    • 0033064676 scopus 로고    scopus 로고
    • Altered mechanics of cartilage with osteoarthritis: Human osteoarthritis and an experimental model of joint degeneration
    • DOI 10.1053/joca.1998.0170
    • LA Setton, DM Elliott and VC Mow: Altered mechanics of cartilage with osteoarthritis: human osteoarthritis and an experimental model of joint degeneration. Osteoarthritis Cartilage, 7(1), 2-14 (1999) (Pubitemid 29112956)
    • (1999) Osteoarthritis and Cartilage , vol.7 , Issue.1 , pp. 2-14
    • Setton, L.A.1    Elliott, D.M.2    Mow, V.C.3
  • 60
    • 0033567935 scopus 로고    scopus 로고
    • Signal transduction by β1 integrin receptors in human chondrocytes in vitro: Collaboration with the insulin-like growth factor-I receptor
    • DOI 10.1042/0264-6021:3420615
    • M Shakibaei, T John, P De Souza, R Rahmanzadeh and HJ Merker: Signal transduction by beta1 integrin receptors in human chondrocytes in vitro: collaboration with the insulin-like growth factor-I receptor. Biochem J, 342 Pt 3, 615-23 (1999) (Pubitemid 29452646)
    • (1999) Biochemical Journal , vol.342 , Issue.3 , pp. 615-623
    • Shakibaei, M.1    John, T.2    De Souza, P.3    Rahmanzadeh, R.4    Merker, H.-J.5
  • 62
    • 4344604554 scopus 로고    scopus 로고
    • Aging theories of primary osteoarthritis: From epidemiology to molecular biology
    • DOI 10.1089/1549168041552964
    • T Aigner, J Rose, J Martin and J Buckwalter: Aging theories of primary osteoarthritis: from epidemiology to molecular biology. Rejuvenation Res, 7(2), 134-45 (2004) (Pubitemid 39150064)
    • (2004) Rejuvenation Research , vol.7 , Issue.2 , pp. 134-145
    • Aigner, T.1    Rose, J.2    Martin, J.3    Buckwalter, J.4
  • 63
    • 66149180583 scopus 로고    scopus 로고
    • Developments in the scientific understanding of osteoarthritis
    • SB Abramson and M Attur: Developments in the scientific understanding of osteoarthritis. Arthritis Res Ther, 11(3), 227 (2009)
    • (2009) Arthritis Res Ther , vol.11 , Issue.3 , pp. 227
    • Abramson, S.B.1    Attur, M.2
  • 64
    • 21444438306 scopus 로고    scopus 로고
    • Pharmaceutical and nutraceutical management of canine osteoarthritis: Present and future perspectives
    • DOI 10.1016/j.tvjl.2004.08.014, PII S1090023304001856
    • Y Henrotin, C Sanchez and M Balligand: Pharmaceutical and nutraceutical management of canine osteoarthritis: Present and future perspectives. The Veterinary Journal, 170(1), 113-123 (2005) (Pubitemid 40916341)
    • (2005) Veterinary Journal , vol.170 , Issue.1 , pp. 113-123
    • Henrotin, Y.1    Sanchez, C.2    Balligand, M.3
  • 65
    • 30944435871 scopus 로고    scopus 로고
    • Medical treatment of osteoarthritis in the horse - A review
    • DOI 10.1016/j.tvjl.2004.07.008, PII S109002330400173X
    • LR Goodrich and AJ Nixon: Medical treatment of osteoarthritis in the horse - A review. The Veterinary Journal, 171(1), 51-69 (2006) (Pubitemid 43116335)
    • (2006) Veterinary Journal , vol.171 , Issue.1 , pp. 51-69
    • Goodrich, L.R.1    Nixon, A.J.2
  • 67
    • 0242664787 scopus 로고    scopus 로고
    • A bit of give and take: The relationship between the extracellular matrix and the developing chondrocyte
    • DOI 10.1016/j.mod.2003.05.002
    • DJ Behonick and Z Werb: A bit of give and take: the relationship between the extracellular matrix and the developing chondrocyte. Mechanisms of Development, 120(11), 1327-1336 (2003) (Pubitemid 37421166)
    • (2003) Mechanisms of Development , vol.120 , Issue.11 , pp. 1327-1336
    • Behonick, D.J.1    Werb, Z.2
  • 68
    • 56649084972 scopus 로고    scopus 로고
    • Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks
    • D Iliopoulos, KN Malizos, P Oikonomou and A Tsezou: Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS One, 3(11), e3740 (2008)
    • (2008) PLoS One , vol.3 , Issue.11
    • Iliopoulos, D.1    Malizos, K.N.2    Oikonomou, P.3    Tsezou, A.4
  • 69
    • 58249099951 scopus 로고    scopus 로고
    • Differential expression of alphaB-crystallin and evidence of its role as a mediator of matrix gene expression in osteoarthritis
    • S Lambrecht, G Verbruggen, D Elewaut and D Deforce: Differential expression of alphaB-crystallin and evidence of its role as a mediator of matrix gene expression in osteoarthritis. Arthritis Rheum, 60(1), 179-88 (2009)
    • (2009) Arthritis Rheum , vol.60 , Issue.1 , pp. 179-188
    • Lambrecht, S.1    Verbruggen, G.2    Elewaut, D.3    Deforce, D.4
  • 70
    • 56849129748 scopus 로고    scopus 로고
    • The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis
    • S Sutton, A Clutterbuck, P Harris, T Gent, S Freeman, N Foster, R Barrett-Jolley and A Mobasheri: The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis. Vet J, 179(1), 10-24 (2009)
    • (2009) Vet J , vol.179 , Issue.1 , pp. 10-24
    • Sutton, S.1    Clutterbuck, A.2    Harris, P.3    Gent, T.4    Freeman, S.5    Foster, N.6    Barrett-Jolley, R.7    Mobasheri, A.8
  • 72
    • 30544448357 scopus 로고    scopus 로고
    • Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments
    • DOI 10.1016/j.joca.2005.07.018, PII S1063458405002025
    • A Struglics, S Larsson, MA Pratta, S Kumar, MW Lark and LS Lohmander: Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase-and matrix metalloproteinase-generated aggrecan fragments. Osteoarthritis and Cartilage, 14(2), 101-113 (2006) (Pubitemid 43079306)
    • (2006) Osteoarthritis and Cartilage , vol.14 , Issue.2 , pp. 101-113
    • Struglics, A.1    Larsson, S.2    Pratta, M.A.3    Kumar, S.4    Lark, M.W.5    Lohmander, L.S.6
  • 73
    • 67949091112 scopus 로고    scopus 로고
    • A review of the differences between normal and osteoarthritis articular cartilage in human knee and ankle joints
    • LHendren and P Beeson: A review of the differences between normal and osteoarthritis articular cartilage in human knee and ankle joints. The Foot, 19(3), 171-176 (2009)
    • (2009) The Foot , vol.19 , Issue.3 , pp. 171-176
    • Hendren, L.1    Beeson, P.2
  • 74
    • 33744798189 scopus 로고    scopus 로고
    • Osteoarthritis: Cellular and molecular changes in degenerating cartilage
    • DOI 10.1016/j.proghi.2006.02.003, PII S0079633606000052
    • H Lorenz and W Richter: Osteoarthritis: Cellular and molecular changes in degenerating cartilage. Progress in Histochemistry and Cytochemistry, 40(3), 135-163 (2006) (Pubitemid 43833326)
    • (2006) Progress in Histochemistry and Cytochemistry , vol.40 , Issue.3 , pp. 135-163
    • Lorenz, H.1    Richter, W.2
  • 76
    • 67649518014 scopus 로고    scopus 로고
    • Proteomics: Addressing the challenges of osteoarthritis
    • F De Ceuninck and F Berenbaum: Proteomics: addressing the challenges of osteoarthritis. Drug Discov Today, 14(13-14), 661-7 (2009)
    • (2009) Drug Discov Today , vol.14 , Issue.13-14 , pp. 661-667
    • De Ceuninck, F.1    Berenbaum, F.2
  • 77
    • 71649113438 scopus 로고    scopus 로고
    • Strategies to optimize twodimensional gel electrophoresis analysis of the human joint proteome
    • C Ruiz-Romero, V Calamia, V Carreira, J Mateos, P Fernandez and FJ Blanco: Strategies to optimize twodimensional gel electrophoresis analysis of the human joint proteome. Talanta, 80(4), 1552-60 (2010)
    • (2010) Talanta , vol.80 , Issue.4 , pp. 1552-1560
    • Ruiz-Romero, C.1    Calamia, V.2    Carreira, V.3    Mateos, J.4    Fernandez, P.5    Blanco, F.J.6
  • 78
    • 67349087532 scopus 로고    scopus 로고
    • Proteomics makes progress in cartilage and arthritis research
    • R Wilson, JM Whitelock and JF Bateman: Proteomics makes progress in cartilage and arthritis research. Matrix Biol, 28(3), 121-8 (2009)
    • (2009) Matrix Biol , vol.28 , Issue.3 , pp. 121-128
    • Wilson, R.1    Whitelock, J.M.2    Bateman, J.F.3
  • 79
    • 77957220211 scopus 로고    scopus 로고
    • Twodimensional gel electrophoresis in proteomics: Past, present and future
    • T Rabilloud, M Chevallet, S Luche and C Lelong: Twodimensional gel electrophoresis in proteomics: past, present and future. J Proteomics, 73(11), 2064-77 (2010)
    • (2010) J Proteomics , vol.73 , Issue.11 , pp. 2064-2077
    • Rabilloud, T.1    Chevallet, M.2    Luche, S.3    Lelong, C.4
  • 81
    • 67651161904 scopus 로고    scopus 로고
    • Design of highdensity antibody microarrays for disease proteomics: Key technological issues
    • CAK Borrebaeck and C Wingren: Design of highdensity antibody microarrays for disease proteomics: Key technological issues. Journal of Proteomics, 72(6), 928-935 (2009)
    • (2009) Journal of Proteomics , vol.72 , Issue.6 , pp. 928-935
    • Borrebaeck, C.1    Wingren, C.2
  • 84
    • 36049047977 scopus 로고    scopus 로고
    • Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis
    • DOI 10.1002/art.22876
    • J Wu, W Liu, A Bemis, E Wang, Y Qiu, EA Morris, CR Flannery and Z Yang: Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis. Arthritis Rheum, 56(11), 3675-84 (2007) (Pubitemid 350100702)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.11 , pp. 3675-3684
    • Wu, J.1    Liu, W.2    Bemis, A.3    Wang, E.4    Qiu, Y.5    Morris, E.A.6    Flannery, C.R.7    Yang, Z.8
  • 85
    • 46449114036 scopus 로고    scopus 로고
    • Proteomic analysis of human articular cartilage: Identification of differentially expressed proteins in knee osteoarthritis
    • D Guo, W Tan, F Wang, Z Lv, J Hu, T Lv, Q Chen, X Gu, B Wan and Z Zhang: Proteomic analysis of human articular cartilage: identification of differentially expressed proteins in knee osteoarthritis. Joint Bone Spine, 75(4), 439-44 (2008)
    • (2008) Joint Bone Spine , vol.75 , Issue.4 , pp. 439-444
    • Guo, D.1    Tan, W.2    Wang, F.3    Lv, Z.4    Hu, J.5    Lv, T.6    Chen, Q.7    Gu, X.8    Wan, B.9    Zhang, Z.10
  • 86
    • 38949172431 scopus 로고    scopus 로고
    • Proteomic analysis of the LPS-induced stress response in rat chondrocytes reveals induction of innate immune response components in articular cartilage
    • DOI 10.1016/j.matbio.2007.09.009, PII S0945053X07001126
    • L Haglund, SM Bernier, P Onnerfjord and AD Recklies: Proteomic analysis of the LPS-induced stress response in rat chondrocytes reveals induction of innate immune response components in articular cartilage. Matrix Biol, 27(2), 107-18 (2008) (Pubitemid 351227379)
    • (2008) Matrix Biology , vol.27 , Issue.2 , pp. 107-118
    • Haglund, L.1    Bernier, S.M.2    Onnerfjord, P.3    Recklies, A.D.4
  • 88
    • 6344270259 scopus 로고    scopus 로고
    • Proteomic analysis of articular cartilage shows increased type II collagen synthesis in osteoarthritis and expression of inhibin βA (activin A), a regulatory molecule for chondrocytes
    • DOI 10.1074/jbc.M407041200
    • M Hermansson, Y Sawaji, M Bolton, S Alexander, A Wallace, S.Begum, R Wait and J Saklatvala: Proteomic analysis of articular cartilage shows increased type II collagen synthesis in osteoarthritis and expression of inhibin betaA (activin A), a regulatory molecule for chondrocytes. J Biol Chem, 279(42), 43514-21 (2004) (Pubitemid 39390651)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.42 , pp. 43514-43521
    • Hermansson, M.1    Sawaji, Y.2    Bolton, M.3    Alexander, S.4    Wallace, A.5    Begum, S.6    Wait, R.7    Saklatvala, J.8
  • 90
    • 33845914595 scopus 로고    scopus 로고
    • Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: From in vitro to in vivo
    • DOI 10.1016/j.ab.2006.10.034, PII S0003269706007780
    • OV Nemirovskiy, DR Dufield, T Sunyer, P Aggarwal, DJ Welsch and WR Mathews: Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: from in vitro to in vivo. Anal Biochem, 361(1), 93-101 (2007) (Pubitemid 46026997)
    • (2007) Analytical Biochemistry , vol.361 , Issue.1 , pp. 93-101
    • Nemirovskiy, O.V.1    Dufield, D.R.2    Sunyer, T.3    Aggarwal, P.4    Welsch, D.J.5    Mathews, W.R.6
  • 92
    • 39749145083 scopus 로고    scopus 로고
    • A sodium dodecyl sulfate-polyacrylamide gel electrophoresis-liquid chromatography tandem mass spectrometry analysis of bovine cartilage tissue response to mechanical compression injury and the inflammatory cytokines tumor necrosis factor α and interleukin-1β
    • DOI 10.1002/art.23120
    • AL Stevens, JS Wishnok, DH. Chai, AJ Grodzinsky and SR Tannenbaum: A sodium dodecyl sulfatepolyacrylamide gel electrophoresis-liquid chromatography tandem mass spectrometry analysis of bovine cartilage tissue response to mechanical compression injury and the inflammatory cytokines tumor necrosis factor alpha and interleukin-1beta. Arthritis Rheum, 58(2), 489-500 (2008) (Pubitemid 351294883)
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.2 , pp. 489-500
    • Stevens, A.L.1    Wishnok, J.S.2    Chai, D.H.3    Grodzinsky, A.J.4    Tannenbaum, S.R.5
  • 93
    • 77954745768 scopus 로고    scopus 로고
    • Differences in the secretome of cartilage explants and cultured chondrocytes unveiled by SILAC technology
    • M Polacek, JA Bruun, O Johansen and I Martinez: Differences in the secretome of cartilage explants and cultured chondrocytes unveiled by SILAC technology. J Orthop Res, 28(8), 1040-1049 (2010)
    • (2010) J Orthop Res , vol.28 , Issue.8 , pp. 1040-1049
    • Polacek, M.1    Bruun, J.A.2    Johansen, O.3    Martinez, I.4
  • 94
    • 4544339999 scopus 로고    scopus 로고
    • The inflammatory side of human chondrocytes unveiled by antibody microarrays
    • DOI 10.1016/j.bbrc.2004.08.184, PII S0006291X04019345
    • F De Ceuninck, L Dassencourt and P Anract: The inflammatory side of human chondrocytes unveiled by antibody microarrays. Biochem Biophys Res Commun, 323(3), 960-9 (2004) (Pubitemid 39243413)
    • (2004) Biochemical and Biophysical Research Communications , vol.323 , Issue.3 , pp. 960-969
    • De Ceuninck, F.1    Dassencourt, L.2    Anract, P.3
  • 95
    • 33749588883 scopus 로고    scopus 로고
    • Development of a novel 2D proteomics approach for the identification of proteins secreted by primary chondrocytes after stimulation by IL-1 and oncostatin M
    • DOI 10.1093/rheumatology/kel060
    • JB Catterall, AD Rowan, S Sarsfield, J Saklatvala, R Wait and TE Cawston: Development of a novel 2D proteomics approach for the identification of proteins secreted by primary chondrocytes after stimulation by IL-1 and oncostatin M. Rheumatology (Oxford), 45(9), 1101-9 (2006) (Pubitemid 44542097)
    • (2006) Rheumatology , vol.45 , Issue.9 , pp. 1101-1109
    • Catterall, J.B.1    Rowan, A.D.2    Sarsfield, S.3    Saklatvala, J.4    Wait, R.5    Cawston, T.E.6
  • 97
    • 59649115416 scopus 로고    scopus 로고
    • Expression, regulation, and signaling of the pattern-recognition receptor nucleotide-binding oligomerization domain 2 in rheumatoid arthritis synovial fibroblasts
    • C Ospelt, F Brentano, A Jungel, Y Rengel, C Kolling, BA Michel, RE Gay and S Gay: Expression, regulation, and signaling of the pattern-recognition receptor nucleotide-binding oligomerization domain 2 in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum, 60(2), 355-63 (2009)
    • (2009) Arthritis Rheum , vol.60 , Issue.2 , pp. 355-363
    • Ospelt, C.1    Brentano, F.2    Jungel, A.3    Rengel, Y.4    Kolling, C.5    Michel, B.A.6    Gay, R.E.7    Gay, S.8
  • 98
    • 70449625015 scopus 로고    scopus 로고
    • The role of toll-like receptors in rheumatoid arthritis
    • QQ Huang and RM Pope: The role of toll-like receptors in rheumatoid arthritis. Curr Rheumatol Rep, 11(5), 357-64 (2009)
    • (2009) Curr Rheumatol Rep , vol.11 , Issue.5 , pp. 357-364
    • Huang, Q.Q.1    Pope, R.M.2
  • 99
    • 65649087479 scopus 로고    scopus 로고
    • Toll-like receptors and rheumatoid arthritis
    • F Brentano, D Kyburz and S Gay: Toll-like receptors and rheumatoid arthritis. Methods Mol Biol, 517, 329-43 (2009)
    • (2009) Methods Mol Biol , vol.517 , pp. 329-343
    • Brentano, F.1    Kyburz, D.2    Gay, S.3
  • 100
    • 26444600233 scopus 로고    scopus 로고
    • Expression and regulation of Toll-like receptor 2 by IL-1β and fibronectin fragments in human articular chondrocytes
    • DOI 10.1016/j.joca.2005.04.017, PII S1063458405001159
    • SL Su, CD Tsai, CH Lee, DM Salter and HS Lee: Expression and regulation of Toll-like receptor 2 by IL1beta and fibronectin fragments in human articular chondrocytes. Osteoarthritis Cartilage, 13(10), 879-86 (2005) (Pubitemid 41430793)
    • (2005) Osteoarthritis and Cartilage , vol.13 , Issue.10 , pp. 879-886
    • Su, S.-L.1    Tsai, C.-D.2    Lee, C.-H.3    Salter, D.M.4    Lee, H.-S.5
  • 101
    • 17144371314 scopus 로고    scopus 로고
    • TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation
    • R Liu-Bryan, K Pritzker, GS Firestein and R Terkeltaub: TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystalinduced nitric oxide generation. J Immunol, 174(8), 5016-23 (2005) (Pubitemid 40514462)
    • (2005) Journal of Immunology , vol.174 , Issue.8 , pp. 5016-5023
    • Liu-Bryan, R.1    Pritzker, K.2    Firestein, G.S.3    Terkeltaub, R.4
  • 102
    • 75649099044 scopus 로고    scopus 로고
    • Lessons from animal models of arthritis over the past decade
    • WB van den Berg: Lessons from animal models of arthritis over the past decade. Arthritis Res Ther, 11(5), 250 (2009)
    • (2009) Arthritis Res Ther , vol.11 , Issue.5 , pp. 250
    • Van Den Berg, W.B.1
  • 103
    • 77956637470 scopus 로고    scopus 로고
    • Expression of Toll-like receptors 2 and 4 in stifle joint synovial tissues of dogs with or without osteoarthritis
    • K Kuroki, AM Stoker, HJ Sims and JL Cook: Expression of Toll-like receptors 2 and 4 in stifle joint synovial tissues of dogs with or without osteoarthritis. Am J Vet Res, 71(7), 750-4 (2010)
    • (2010) Am J Vet Res , vol.71 , Issue.7 , pp. 750-754
    • Kuroki, K.1    Stoker, A.M.2    Sims, H.J.3    Cook, J.L.4
  • 104
    • 23844482134 scopus 로고    scopus 로고
    • Proteomic characterization of human normal articular chondrocytes: A novel tool for the study of osteoarthritis and other rheumatic diseases
    • DOI 10.1002/pmic.200402106
    • C Ruiz-Romero, MJ Lopez-Armada and FJ Blanco: Proteomic characterization of human normal articular chondrocytes: a novel tool for the study of osteoarthritis and other rheumatic diseases. Proteomics, 5(12), 3048-59 (2005) (Pubitemid 41176471)
    • (2005) Proteomics , vol.5 , Issue.12 , pp. 3048-3059
    • Ruiz-Romero, C.1    Lopez-Armada, M.J.2    Blanco, F.J.3
  • 105
    • 77649158518 scopus 로고    scopus 로고
    • Proteomic analysis by twodimensional electrophoresis to identify the normal human chondrocyte proteome stimulated by tumor necrosis factor alpha and interleukin-1beta
    • B Cillero-Pastor, C Ruiz-Romero, B Carames, MJ Lopez-Armada and FJ Blanco: Proteomic analysis by twodimensional electrophoresis to identify the normal human chondrocyte proteome stimulated by tumor necrosis factor alpha and interleukin-1beta. Arthritis Rheum, 62(3), 802-14 (2010)
    • (2010) Arthritis Rheum , vol.62 , Issue.3 , pp. 802-814
    • Cillero-Pastor, B.1    Ruiz-Romero, C.2    Carames, B.3    Lopez-Armada, M.J.4    Blanco, F.J.5
  • 106
    • 38949207162 scopus 로고    scopus 로고
    • Differential proteome analysis of normal and osteoarthritic chondrocytes reveals distortion of vimentin network in osteoarthritis
    • DOI 10.1016/j.joca.2007.06.005, PII S1063458407002233
    • S Lambrecht, G Verbruggen, PC Verdonk, D Elewaut and D Deforce: Differential proteome analysis of normal and osteoarthritic chondrocytes reveals distortion of vimentin network in osteoarthritis. Osteoarthritis Cartilage, 16(2), 163-73 (2008) (Pubitemid 351218181)
    • (2008) Osteoarthritis and Cartilage , vol.16 , Issue.2 , pp. 163-173
    • Lambrecht, S.1    Verbruggen, G.2    Verdonk, P.C.M.3    Elewaut, D.4    Deforce, D.5
  • 107
    • 77952062482 scopus 로고    scopus 로고
    • Differential protein expression in human articular chondrocytes expanded in serum-free media of different medium osmolalities by DIGE
    • J Koo, KI Kim, BH Min and GM Lee: Differential protein expression in human articular chondrocytes expanded in serum-free media of different medium osmolalities by DIGE. J Proteome Res, 9(5), 2480-7 (2010)
    • (2010) J Proteome Res , vol.9 , Issue.5 , pp. 2480-2487
    • Koo, J.1    Kim, K.I.2    Min, B.H.3    Lee, G.M.4
  • 109
    • 34548451974 scopus 로고    scopus 로고
    • Reactive oxygen species in mitochondria-mediated cell death
    • DOI 10.1080/03602530701468516, PII 781828662
    • S Orrenius: Reactive oxygen species in mitochondriamediated cell death. Drug Metab Rev, 39(2-3), 443-55 (2007) (Pubitemid 47355728)
    • (2007) Drug Metabolism Reviews , vol.39 , Issue.2-3 , pp. 443-455
    • Orrenius, S.1
  • 110
    • 4344693235 scopus 로고    scopus 로고
    • Mitochondrial signaling pathways: A receiver/integrator organelle
    • DOI 10.1023/B:MCBI.0000038228.85494.3b
    • MJ Goldenthal and J Marin-Garcia: Mitochondrial signaling pathways: a receiver/integrator organelle. Mol Cell Biochem, 262(1-2), 1-16 (2004) (Pubitemid 39158049)
    • (2004) Molecular and Cellular Biochemistry , vol.262 , Issue.1-2 , pp. 1-16
    • Goldenthal, M.J.1    Marin-Garcia, J.2
  • 112
    • 0034525374 scopus 로고    scopus 로고
    • The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability
    • DOI 10.1038/sj.cdd.4400781
    • MH Harris and CB Thompson: The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability. Cell Death Differ, 7(12), 1182-91 (2000) (Pubitemid 32042225)
    • (2000) Cell Death and Differentiation , vol.7 , Issue.12 , pp. 1182-1191
    • Harris, M.H.1    Thompson, C.B.2
  • 113
    • 0033667521 scopus 로고    scopus 로고
    • Role of mitochondria in neuronal apoptosis
    • AM Gorman, S Ceccatelli and S Orrenius: Role of mitochondria in neuronal apoptosis. Dev Neurosci, 22(5-6), 348-58 (2000)
    • (2000) Dev Neurosci , vol.22 , Issue.5-6 , pp. 348-358
    • Gorman, A.M.1    Ceccatelli, S.2    Orrenius, S.3
  • 114
    • 67649439168 scopus 로고    scopus 로고
    • Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage
    • SC Rosa, J Goncalves, F Judas, A Mobasheri, C Lopes and AF Mendes: Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage. Arthritis Res Ther, 11(3), R80 (2009)
    • (2009) Arthritis Res Ther , vol.11 , Issue.3
    • Rosa, S.C.1    Goncalves, J.2    Judas, F.3    Mobasheri, A.4    Lopes, C.5    Mendes, A.F.6
  • 115
    • 63349105399 scopus 로고    scopus 로고
    • Effects of hypoxia on glucose transport in primary equine chondrocytes in vitro and evidence of reduced GLUT1 gene expression in pathologic cartilage in vivo
    • S Peansukmanee, A Vaughan-Thomas, SD Carter, PD Clegg, S Taylor, C Redmond and A Mobasheri: Effects of hypoxia on glucose transport in primary equine chondrocytes in vitro and evidence of reduced GLUT1 gene expression in pathologic cartilage in vivo. J Orthop Res, 27(4), 529-35 (2009)
    • (2009) J Orthop Res , vol.27 , Issue.4 , pp. 529-535
    • Peansukmanee, S.1    Vaughan-Thomas, A.2    Carter, S.D.3    Clegg, P.D.4    Taylor, S.5    Redmond, C.6    Mobasheri, A.7
  • 116
    • 41049084437 scopus 로고    scopus 로고
    • Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1alpha in normal and degenerate human intervertebral disc
    • SM Richardson, R Knowles, J Tyler, A Mobasheri and JA Hoyland: Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1alpha in normal and degenerate human intervertebral disc. Histochem Cell Biol, 129(4), 503-11 (2008)
    • (2008) Histochem Cell Biol , vol.129 , Issue.4 , pp. 503-511
    • Richardson, S.M.1    Knowles, R.2    Tyler, J.3    Mobasheri, A.4    Hoyland, J.A.5
  • 117
    • 59149096239 scopus 로고    scopus 로고
    • Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: A decrease in mitochondrial superoxide dismutase points to a redox imbalance
    • C Ruiz-Romero, V Calamia, J Mateos, V Carreira, M Martinez-Gomariz, M Fernandez and FJ Blanco: Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalance. Mol Cell Proteomics, 8(1), 172-89 (2009)
    • (2009) Mol Cell Proteomics , vol.8 , Issue.1 , pp. 172-189
    • Ruiz-Romero, C.1    Calamia, V.2    Mateos, J.3    Carreira, V.4    Martinez-Gomariz, M.5    Fernandez, M.6    Blanco, F.J.7
  • 119
    • 33646863322 scopus 로고    scopus 로고
    • Mitochondrial proteomic characterization of human normal articular chondrocytes
    • DOI 10.1016/j.joca.2005.12.004, PII S1063458405003651
    • C Ruiz-Romero, MJ Lopez-Armada and FJ Blanco: Mitochondrial proteomic characterization of human normal articular chondrocytes. Osteoarthritis Cartilage, 14(6), 507-18 (2006) (Pubitemid 43785847)
    • (2006) Osteoarthritis and Cartilage , vol.14 , Issue.6 , pp. 507-518
    • Ruiz-Romero, C.1    Lopez-Armada, M.J.2    Blanco, F.J.3
  • 120
    • 10644271561 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in osteoarthritis
    • DOI 10.1016/j.mito.2004.07.022, PII S1567724904001606
    • FJ Blanco, MJ Lopez-Armada and E Maneiro: Mitochondrial dysfunction in osteoarthritis. Mitochondrion, 4(5-6), 715-28 (2004) (Pubitemid 39646817)
    • (2004) Mitochondrion , vol.4 , Issue.5-6 SPEC. ISSUE , pp. 715-728
    • Blanco, F.J.1    Lopez-Armada, M.J.2    Maneiro, E.3
  • 124
    • 10644271561 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in osteoarthritis
    • DOI 10.1016/j.mito.2004.07.022, PII S1567724904001606
    • FJ Blanco, MJ López-Armada and E Maneiro: Mitochondrial dysfunction in osteoarthritis. Mitochondrion, 4(5-6), 715-728 (2004) (Pubitemid 39646817)
    • (2004) Mitochondrion , vol.4 , Issue.5-6 SPEC. ISSUE , pp. 715-728
    • Blanco, F.J.1    Lopez-Armada, M.J.2    Maneiro, E.3
  • 125
    • 0036709460 scopus 로고    scopus 로고
    • Mass spectrometric proteome analyses of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactive arthritis or osteoarthritis
    • DOI 10.1002/1522-2683(200210)23:1 9<3445::AID-ELPS3445>3.0.CO;2-J
    • A Sinz, M Bantscheff, S Mikkat, B Ringel, S Drynda, J Kekow, HJ Thiesen and MO Glocker: Mass spectrometric proteome analyses of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactive arthritis or osteoarthritis. Electrophoresis, 23(19), 3445-56 (2002) (Pubitemid 35230230)
    • (2002) Electrophoresis , vol.23 , Issue.19 , pp. 3445-3456
    • Sinz, A.1    Bantscheff, M.2    Mikkat, S.3    Ringel, B.4    Drynda, S.5    Kekow, J.6    Thiesen, H.-J.7    Glocker, M.O.8
  • 126
    • 0042513861 scopus 로고    scopus 로고
    • Two-dimensional gel electrophoresis of synovial fluid: Method for detecting candidate protein markers for osteoarthritis
    • DOI 10.1007/s00776-003-0657-3
    • H Yamagiwa, G Sarkar, MC Charlesworth, DJ McCormick and ME Bolander: Two-dimensional gel electrophoresis of synovial fluid: method for detecting candidate protein markers for osteoarthritis. J Orthop Sci, 8(4), 482-90 (2003) (Pubitemid 37012058)
    • (2003) Journal of Orthopaedic Science , vol.8 , Issue.4 , pp. 482-490
    • Yamagiwa, H.1    Sarkar, G.2    Charlesworth, M.C.3    McCormick, D.J.4    Bolander, M.E.5
  • 127
    • 3242733262 scopus 로고    scopus 로고
    • Proteome analysis reveals disease-associated marker proteins to differentiate RA patients from other inflammatory joint diseases with the potential to monitor anti-TNFα therapy
    • DOI 10.1016/j.prp.2004.02.011, PII S0344033804000354, Proteomics in Pathology, Research and Practice
    • S Drynda, B Ringel, M Kekow, C Kuhne, A Drynda, MO Glocker, HJ Thiesen and J Kekow: Proteome analysis reveals disease-associated marker proteins to differentiate RA patients from other inflammatory joint diseases with the potential to monitor anti-TNFalpha therapy. Pathol Res Pract, 200(2), 165-71 (2004) (Pubitemid 38950446)
    • (2004) Pathology Research and Practice , vol.200 , Issue.2 , pp. 165-171
    • Drynda, S.1    Ringel, B.2    Kekow, M.3    Kuhne, C.4    Drynda, A.5    Glocker, M.O.6    Thiesen, H.-J.7    Kekow, J.8
  • 128
    • 0036580943 scopus 로고    scopus 로고
    • S100 proteins: Structure, functions and pathology
    • CW Heizmann, G Fritz and BW Schafer: S100 proteins: structure, functions and pathology. Front Biosci, 7, d1356-68 (2002)
    • (2002) Front Biosci , vol.7
    • Heizmann, C.W.1    Fritz, G.2    Schafer, B.W.3
  • 129
    • 0028928357 scopus 로고
    • The S100 protein family: History, function, and expression
    • DB Zimmer, EH Cornwall, A Landar and W Song: The S100 protein family: history, function, and expression. Brain Res Bull, 37(4), 417-29 (1995)
    • (1995) Brain Res Bull , vol.37 , Issue.4 , pp. 417-429
    • Zimmer, D.B.1    Cornwall, E.H.2    Landar, A.3    Song, W.4
  • 130
    • 34548182124 scopus 로고    scopus 로고
    • Identification of differentially secreted biomarkers using LC-MS/MS in isogenic cell lines representing a progression of breast cancer
    • DOI 10.1021/pr060629m
    • F Mbeunkui, BJ Metge, LA Shevde and LK Pannell: Identification of differentially secreted biomarkers using LCMS/MS in isogenic cell lines representing a progression of breast cancer. J Proteome Res, 6(8), 2993-3002 (2007) (Pubitemid 47310184)
    • (2007) Journal of Proteome Research , vol.6 , Issue.8 , pp. 2993-3002
    • Mbeunkui, F.1    Metge, B.J.2    Shevde, L.A.3    Pannell, L.K.4
  • 134
    • 0038047126 scopus 로고    scopus 로고
    • From transcriptome to proteome: Differentially expressed proteins identified in synovial tissue of patients suffering from rheumatoid arthritis and osteoarthritis by an initial screen with a panel of 791 antibodies
    • DOI 10.1002/pmic.200300412
    • P Lorenz, P Ruschpler, D Koczan, P Stiehl and HJ Thiesen: From transcriptome to proteome: differentially expressed proteins identified in synovial tissue of patients suffering from rheumatoid arthritis and osteoarthritis by an initial screen with a panel of 791 antibodies. Proteomics, 3(6), 991-1002 (2003) (Pubitemid 36801687)
    • (2003) Proteomics , vol.3 , Issue.6 , pp. 991-1002
    • Lorenz, P.1    Ruschpler, P.2    Koczan, D.3    Stiehl, P.4    Thiesen, H.-J.5
  • 135
    • 20044396776 scopus 로고    scopus 로고
    • Chronically inflamed synovium from spondyloarthropathy and rheumatoid arthritis investigated by protein expression profiling followed by tandem mass spectrometry
    • DOI 10.1002/pmic.200401109
    • K Tilleman, K Van Beneden, A Dhondt, I Hoffman, F De Keyser, E Veys, D Elewaut and D Deforce: Chronically inflamed synovium from spondyloarthropathy and rheumatoid arthritis investigated by protein expression profiling followed by tandem mass spectrometry. Proteomics, 5(8), 2247-57 (2005) (Pubitemid 40770586)
    • (2005) Proteomics , vol.5 , Issue.8 , pp. 2247-2257
    • Tilleman, K.1    Van Beneden, K.2    Dhondt, A.3    Hoffman, I.4    De Keyset, F.5    Veys, E.6    Elewaul, D.7    Deforce, D.8
  • 136
    • 33845914595 scopus 로고    scopus 로고
    • Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: From in vitro to in vivo
    • DOI 10.1016/j.ab.2006.10.034, PII S0003269706007780
    • OV Nemirovskiy, DR Dufield, T Sunyer, P Aggarwal, DJ Welsch and WR Mathews: Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: From in vitro to in vivo. Analytical Biochemistry, 361(1), 93-101 (2007) (Pubitemid 46026997)
    • (2007) Analytical Biochemistry , vol.361 , Issue.1 , pp. 93-101
    • Nemirovskiy, O.V.1    Dufield, D.R.2    Sunyer, T.3    Aggarwal, P.4    Welsch, D.J.5    Mathews, W.R.6
  • 137
    • 77955506817 scopus 로고    scopus 로고
    • Design and validation of an immunoaffinity LC-MS/MS assay for the quantification of a collagen type II neoepitope peptide in human urine: Application as a biomarker of osteoarthritis
    • O Nemirovskiy, WW Li and G Szekely-Klepser: Design and validation of an immunoaffinity LC-MS/MS assay for the quantification of a collagen type II neoepitope peptide in human urine: application as a biomarker of osteoarthritis. Methods Mol Biol, 641, 253-70 (2010)
    • (2010) Methods Mol Biol , vol.641 , pp. 253-270
    • Nemirovskiy, O.1    Li, W.W.2    Szekely-Klepser, G.3
  • 138
    • 34548169013 scopus 로고    scopus 로고
    • Clinical validation of an immunoaffinity LC-MS/MS assay for the quantification of a collagen type II neoepitope peptide: A biomarker of matrix metalloproteinase activity and osteoarthritis in human urine
    • DOI 10.1016/j.ab.2007.05.002, PII S0003269707003028
    • WW. Li, O Nemirovskiy, S Fountain, W Rodney Mathews and G Szekely-Klepser: Clinical validation of an immunoaffinity LC-MS/MS assay for the quantification of a collagen type II neoepitope peptide: A biomarker of matrix metalloproteinase activity and osteoarthritis in human urine. Anal Biochem, 369(1), 41-53 (2007) (Pubitemid 47313372)
    • (2007) Analytical Biochemistry , vol.369 , Issue.1 , pp. 41-53
    • Li, W.W.1    Nemirovskiy, O.2    Fountain, S.3    Rodney Mathews, W.4    Szekely-Klepser, G.5
  • 139
    • 2342496199 scopus 로고    scopus 로고
    • Proteomic Surveillance of Autoimmunity in Osteoarthritis: Identification of Triosephosphate Isomerase as an Autoantigen in Patients with Osteoarthritis
    • DOI 10.1002/art.20189
    • Y Xiang, T Sekine, H Nakamura, S Imajoh-Ohmi, H Fukuda, K Nishioka and T Kato: Proteomic surveillance of autoimmunity in osteoarthritis: identification of triosephosphate isomerase as an autoantigen in patients with osteoarthritis. Arthritis Rheum, 50(5), 1511-21 (2004) (Pubitemid 38608073)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.5 , pp. 1511-1521
    • Xiang, Y.1    Sekine, T.2    Nakamura, H.3    Imajoh-Ohmi, S.4    Fukuda, H.5    Nishioka, K.6    Kato, T.7
  • 140
    • 47549090650 scopus 로고    scopus 로고
    • Micro-high-performance liquid chromatography platform for the depletion of high-abundance proteins and subsequent on-line concentration/capturing of medium and low-abundance proteins from serum. Application to profiling of protein expression in healthy and osteoarthritis sera by 2-D gel electrophoresis
    • DOI 10.1002/elps.200800039
    • Y Jmeian and Z El Rassi: Micro-high-performance liquid chromatography platform for the depletion of high-abundance proteins and subsequent on-line concentration/capturing of medium and low-abundance proteins from serum. Application to profiling of protein expression in healthy and osteoarthritis sera by 2-D gel electrophoresis. Electrophoresis, 29(13), 2801-11 (2008) (Pubitemid 352006114)
    • (2008) Electrophoresis , vol.29 , Issue.13 , pp. 2801-2811
    • Jmeian, Y.1    El Rassi, Z.2
  • 141
    • 27344459488 scopus 로고    scopus 로고
    • Biomarkers in osteoarthritis
    • DOI 10.1097/01.bor.0000174195.15421.17
    • VB Kraus: Biomarkers in osteoarthritis. Curr Opin Rheumatol, 17(5), 641-6 (2005) (Pubitemid 41527828)
    • (2005) Current Opinion in Rheumatology , vol.17 , Issue.5 , pp. 641-646
    • Kraus, V.B.1
  • 142
    • 77951068899 scopus 로고    scopus 로고
    • A pathway and approach to biomarker validation and qualification for osteoarthritis clinical trials
    • DJ Hunter, E Losina, A Guermazi, D Burstein, MN Lassere and V Kraus: A pathway and approach to biomarker validation and qualification for osteoarthritis clinical trials. Curr Drug Targets, 11(5), 536-45 (2010)
    • (2010) Curr Drug Targets , vol.11 , Issue.5 , pp. 536-545
    • Hunter, D.J.1    Losina, E.2    Guermazi, A.3    Burstein, D.4    Lassere, M.N.5    Kraus, V.6
  • 145
    • 75649122624 scopus 로고    scopus 로고
    • Biomarkers: In combination they may do better
    • FM Williams: Biomarkers: in combination they may do better. Arthritis Res Ther, 11(5), 130 (2009)
    • (2009) Arthritis Res Ther , vol.11 , Issue.5 , pp. 130
    • Williams, F.M.1
  • 147
    • 0035260226 scopus 로고    scopus 로고
    • A glycomic approach to the identification and characterization of glycoprotein function in cells transfected with glycosyltransferase genes
    • N Taniguchi, A Ekuni, JH Ko, E Miyoshi, Y Ikeda, Y Ihara, A Nishikawa, K Honke and M Takahashi: A glycomic approach to the identification and characterization of glycoprotein function in cells transfected with glycosyltransferase genes. Proteomics, 1(2), 239-47 (2001) (Pubitemid 33586719)
    • (2001) Proteomics , vol.1 , Issue.2 , pp. 239-247
    • Taniguchi, N.1    Ekuni, A.2    Ko, J.H.3    Miyoshi, E.4    Ikeda, Y.5    Ihara, Y.6    Nishikawa, A.7    Honke, K.8    Takahashi, M.9
  • 148
    • 0015332105 scopus 로고
    • Particulate glycosyl-transferases in cartilage and human arthrosis
    • M Richard, E Vignon and P Louisot: Particulate glycosyl-transferases in cartilage and human arthrosis. Rev Eur Etud Clin Biol, 17(5), 503-4 (1972)
    • (1972) Rev Eur Etud Clin Biol , vol.17 , Issue.5 , pp. 503-504
    • Richard, M.1    Vignon, E.2    Louisot, P.3
  • 151
    • 0034066471 scopus 로고    scopus 로고
    • Membrane proteins and proteomics: Un amour impossible?
    • DOI 10.1002/(SICI)1522-2683(20000 401)21:6<1054::AID-ELPS1054>3.0. CO;2-8
    • V Santoni, M Molloy and T Rabilloud: Membrane proteins and proteomics: un amour impossible? Electrophoresis, 21(6), 1054-70 (2000) (Pubitemid 30230772)
    • (2000) Electrophoresis , vol.21 , Issue.6 , pp. 1054-1070
    • Santoni, V.1    Molloy, M.2    Rabilloud, T.3
  • 152
    • 69249222678 scopus 로고    scopus 로고
    • Membrane proteins and proteomics: Love is possible, but so difficult
    • T Rabilloud: Membrane proteins and proteomics: love is possible, but so difficult. Electrophoresis, 30 Suppl 1, S174-80 (2009)
    • (2009) Electrophoresis , vol.30 , Issue.SUPPL. 1
    • Rabilloud, T.1
  • 153
    • 37349110270 scopus 로고    scopus 로고
    • Comparative proteomics and difference gel electrophoresis
    • 741, 743 passim
    • J Minden: Comparative proteomics and difference gel electrophoresis. Biotechniques, 43(6), 739, 741, 743 passim (2007)
    • (2007) Biotechniques , vol.43 , Issue.6 , pp. 739
    • Minden, J.1
  • 154
    • 77956677051 scopus 로고
    • The dual effect of membrane potential on sodium conductance in the giant axon of Loligo
    • AL Hodgkin and AF Huxley: The dual effect of membrane potential on sodium conductance in the giant axon of Loligo. J Physiol, 116(4), 497-506 (1952)
    • (1952) J Physiol , vol.116 , Issue.4 , pp. 497-506
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 155
    • 0026512861 scopus 로고
    • The patch clamp technique
    • E Neher and B Sakmann: The patch clamp technique. Sci Am, 266(3), 44-51 (1992)
    • (1992) Sci Am , vol.266 , Issue.3 , pp. 44-51
    • Neher, E.1    Sakmann, B.2
  • 157
    • 43549094212 scopus 로고    scopus 로고
    • Déjà vu in proteomics. A hit parade of repeatedly identified differentially expressed proteins
    • DOI 10.1002/pmic.200700919
    • J Petrak, R Ivanek, O Toman, R Cmejla, J Cmejlova, D Vyoral, J Zivny and CD Vulpe: Deja vu in proteomics. A hit parade of repeatedly identified differentially expressed proteins. Proteomics, 8(9), 1744-9 (2008) (Pubitemid 351678270)
    • (2008) Proteomics , vol.8 , Issue.9 , pp. 1744-1749
    • Petrak, J.1    Ivanek, R.2    Toman, O.3    Cmejla, R.4    Cmejlova, J.5    Vyoral, D.6    Zivny, J.7    Vulpe, C.D.8
  • 158
    • 67649184787 scopus 로고    scopus 로고
    • Generally detected proteins in comparative proteomics - A matter of cellular stress response?
    • P Wang, FG Bouwman and EC Mariman: Generally detected proteins in comparative proteomics-a matter of cellular stress response? Proteomics, 9(11), 2955-66 (2009)
    • (2009) Proteomics , vol.9 , Issue.11 , pp. 2955-2966
    • Wang, P.1    Bouwman, F.G.2    Mariman, E.C.3


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