메뉴 건너뛰기




Volumn 60, Issue 6, 2011, Pages 1660-1667

Liver enzymes are associated with hepatic insulin resistance, insulin secretion, and glucagon concentration in healthy men and women

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; GAMMA GLUTAMYLTRANSFERASE; GLUCAGON; GLUCOSE; INSULIN;

EID: 79959518068     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-1806     Document Type: Article
Times cited : (116)

References (35)
  • 1
    • 34548381151 scopus 로고    scopus 로고
    • Gamma-Glutamyltransferase activity and development of the metabolic syndrome (International Diabetes Federation Definition) in middle-aged men and women: Data from the epidemiological study on the insulin resistance syndrome (DESIR) cohort
    • DOI 10.2337/dc07-0440
    • André P, Balkau B, Vol S, Charles MA, Eschwège E; DESIR Study Group. Gamma-glutamyltransferase activity and development of the metabolic syndrome (International Diabetes Federation Definition) in middle-aged men and women: data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort. Diabetes Care 2007;30:2355-2361 (Pubitemid 47364644)
    • (2007) Diabetes Care , vol.30 , Issue.9 , pp. 2355-2361
    • Andre, P.1    Balkau, B.2    Vol, S.3    Charles, M.A.4    Eschwege, E.5
  • 2
    • 0031766447 scopus 로고    scopus 로고
    • Prospective study of serum gamma-glutamyltransferase and risk of NIDDM
    • DOI 10.2337/diacare.21.5.732
    • Perry IJ, Wannamethee SG, Shaper AG. Prospective study of serum gamma-glutamyltransferase and risk of NIDDM. Diabetes Care 1998;21:732-737 (Pubitemid 28487063)
    • (1998) Diabetes Care , vol.21 , Issue.5 , pp. 732-737
    • Perry, I.J.1    Wannamethee, S.G.2    Shaper, A.G.3
  • 3
    • 8744291010 scopus 로고    scopus 로고
    • gamma-glutamyltransferase, obesity, and the risk of type 2 diabetes: Observational cohort study among 20,158 middle-aged men and women
    • DOI 10.1210/jc.2004-0505
    • Lee DH, Silventoinen K, Jacobs DR Jr, Jousilahti P, Tuomileto J. gamma- Glutamyltransferase, obesity, and the risk of type 2 diabetes: observational cohort study among 20,158 middle-aged men and women. J Clin Endocrinol Metab 2004;89:5410-5414 (Pubitemid 39518418)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.11 , pp. 5410-5414
    • Duk, H.L.1    Silventoinen, K.2    Jacobs Jr., D.R.3    Jousilahti, P.4    Tuomileto, J.5
  • 4
    • 2542498253 scopus 로고    scopus 로고
    • Serum gamma-glutamyltransferase and risk of metabolic syndrome and type 2 diabetes in middle-aged Japanese men
    • DOI 10.2337/diacare.27.6.1427
    • Nakanishi N, Suzuki K, Tatara K. Serum gamma-glutamyltransferase and risk of metabolic syndrome and type 2 diabetes in middle-aged Japanese men. Diabetes Care 2004;27:1427-1432 (Pubitemid 38679993)
    • (2004) Diabetes Care , vol.27 , Issue.6 , pp. 1427-1432
    • Nakanishi, N.1    Suzuki, K.2    Tatara, K.3
  • 5
    • 33644823983 scopus 로고    scopus 로고
    • Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men
    • DOI 10.2337/diacare.28.12.2913
    • Wannamethee SG, Shaper AG, Lennon L, Whincup PH. Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men. Diabetes Care 2005;28:2913-2918 (Pubitemid 43942924)
    • (2005) Diabetes Care , vol.28 , Issue.12 , pp. 2913-2918
    • Wannamethee, S.G.1    Shaper, A.G.2    Lennon, L.3    Whincup, P.H.4
  • 6
    • 65349101599 scopus 로고    scopus 로고
    • Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: The British Women's Heart and Health Study and meta-analysis
    • Fraser A, Harris R, Sattar N, Ebrahim S, Davey Smith G, Lawlor DA. Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the British Women's Heart and Health Study and meta-analysis. Diabetes Care 2009;32:741-750
    • (2009) Diabetes Care , vol.32 , pp. 741-750
    • Fraser, A.1    Harris, R.2    Sattar, N.3    Ebrahim, S.4    Davey Smith, G.5    Lawlor, D.A.6
  • 7
    • 77949277852 scopus 로고    scopus 로고
    • Risk factors for incident type 2 diabetes in individuals with a BMI of <27 kg/m2: The role of gamma-glutamyltransferase. Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR)
    • DESIR Study Group
    • Gautier A, Balkau B, Lange C, Tichet J, Bonnet F; DESIR Study Group. Risk factors for incident type 2 diabetes in individuals with a BMI of <27 kg/m2: the role of gamma-glutamyltransferase. Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR). Diabetologia 2010;53:247-253
    • (2010) Diabetologia , vol.53 , pp. 247-253
    • Gautier, A.1    Balkau, B.2    Lange, C.3    Tichet, J.4    Bonnet, F.5
  • 9
    • 34447125597 scopus 로고    scopus 로고
    • Alanine aminotransferase and directly measured insulin sensitivity in a multiethnic cohort: The insulin resistance atherosclerosis study
    • DOI 10.2337/dc07-0086
    • Hanley AJ, Wagenknecht LE, Festa A, D'Agostino RB Jr, Haffner SM. Alanine aminotransferase and directly measured insulin sensitivity in a multiethnic cohort: the Insulin Resistance Atherosclerosis Study. Diabetes Care 2007;30:1819-1827 (Pubitemid 47036358)
    • (2007) Diabetes Care , vol.30 , Issue.7 , pp. 1819-1827
    • Hanley, A.J.G.1    Wagenknecht, L.E.2    Festa, A.3    D'Agostino Jr., R.B.4    Haffner, S.M.5
  • 10
    • 1842844418 scopus 로고    scopus 로고
    • The EGIR-RISC Study (The European Group for the study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular disease risk): I. Methodology and objectives
    • EGIR-RISC Study Group
    • Hills SA, Balkau B, Coppack SW, et al.; EGIR-RISC Study Group. The EGIR-RISC Study (The European Group for the study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular disease risk): I. Methodology and objectives. Diabetologia 2004;47:566-570
    • (2004) Diabetologia , vol.47 , pp. 566-570
    • Hills, S.A.1    Balkau, B.2    Coppack, S.W.3
  • 11
    • 48649103968 scopus 로고    scopus 로고
    • Influence of the ACE gene insertion/deletion polymorphism on insulin sensitivity and impaired glucose tolerance in healthy subjects
    • European Group for the study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular disease risk Study Group
    • Bonnet F, Patel S, Laville M, et al.; European Group for the study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular disease risk Study Group. Influence of the ACE gene insertion/deletion polymorphism on insulin sensitivity and impaired glucose tolerance in healthy subjects. Diabetes Care 2008;31:789-794
    • (2008) Diabetes Care , vol.31 , pp. 789-794
    • Bonnet, F.1    Patel, S.2    Laville, M.3
  • 12
    • 1542346857 scopus 로고    scopus 로고
    • Reliability and validity of the International Physical Activity Questionnaire (IPAQ) [2]
    • DOI 10.1249/01.MSS.0000117161.66394.07
    • Hallal PC, Victora CG. Reliability and validity of the International Physical Activity Questionnaire (IPAQ). Med Sci Sports Exerc 2004;36:556 (Pubitemid 38298710)
    • (2004) Medicine and Science in Sports and Exercise , vol.36 , Issue.3 , pp. 556
    • Hallal, P.C.1    Victora, C.G.2
  • 13
    • 24944545643 scopus 로고    scopus 로고
    • Increased serum adiponectin levels in type 1 diabetic patients with microvascular complications
    • DOI 10.1007/s00125-005-1850-z
    • Frystyk J, Tarnow L, Hansen TK, Parving HH, Flyvbjerg A. Increased serum adiponectin levels in type 1 diabetic patients with microvascular complications. Diabetologia 2005;48:1911-1918 (Pubitemid 41317848)
    • (2005) Diabetologia , vol.48 , Issue.9 , pp. 1911-1918
    • Frystyk, J.1    Tarnow, L.2    Krarup, H.T.3    Parving, H.-H.4    Flyvbjerg, A.5
  • 14
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
    • DOI 10.2337/diacare.22.9.1462
    • Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22:1462-1470 (Pubitemid 29418240)
    • (1999) Diabetes Care , vol.22 , Issue.9 , pp. 1462-1470
    • Matsuda, M.1    DeFronzo, R.A.2
  • 16
    • 0026504160 scopus 로고
    • Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance
    • Van Cauter E, Mestrez F, Sturis J, Polonsky KS. Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes 1992;41:368-377
    • (1992) Diabetes , vol.41 , pp. 368-377
    • Van Cauter, E.1    Mestrez, F.2    Sturis, J.3    Polonsky, K.S.4
  • 17
    • 0036263238 scopus 로고    scopus 로고
    • High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes
    • Vozarova B, Stefan N, Lindsay RS, et al. High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 2002;51:1889-1895 (Pubitemid 34564303)
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1889-1895
    • Vozarova, B.1    Stefan, N.2    Lindsay, R.S.3    Saremi, A.4    Pratley, R.E.5    Bogardus, C.6    Antonio, T.P.7
  • 20
    • 48649111041 scopus 로고    scopus 로고
    • Liver enzymes compared with alcohol consumption in predicting the risk of type 2 diabetes: The Kansai Healthcare Study
    • Sato KK, Hayashi T, Nakamura Y, et al. Liver enzymes compared with alcohol consumption in predicting the risk of type 2 diabetes: the Kansai Healthcare Study. Diabetes Care 2008;31:1230-1236
    • (2008) Diabetes Care , vol.31 , pp. 1230-1236
    • Sato, K.K.1    Hayashi, T.2    Nakamura, Y.3
  • 21
    • 2542612878 scopus 로고    scopus 로고
    • Is serum gamma glutamyltransferase a marker of oxidative stress?
    • Lee DH, Blomhoff R, Jacobs DR Jr. Is serum gamma glutamyltransferase a marker of oxidative stress? Free Radic Res 2004;38:535-539
    • (2004) Free Radic Res , vol.38 , pp. 535-539
    • Lee, D.H.1    Blomhoff, R.2    Jacobs Jr., D.R.3
  • 22
    • 67650079371 scopus 로고    scopus 로고
    • Oxidative stress and insulin resistance: The coronary artery risk development in young adults study
    • Park K, Gross M, Lee DH, et al. Oxidative stress and insulin resistance: the coronary artery risk development in young adults study. Diabetes Care 2009;32:1302-1307
    • (2009) Diabetes Care , vol.32 , pp. 1302-1307
    • Park, K.1    Gross, M.2    Lee, D.H.3
  • 23
    • 0024507794 scopus 로고
    • Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: Contributions of excessive hepatic glucose production and impaired tissue glucose uptake
    • DOI 10.1016/0026-0495(89)90129-7
    • DeFronzo RA, Ferrannini E, Simonson DC. Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake. Metabolism 1989;38:387-395 (Pubitemid 19105727)
    • (1989) Metabolism: Clinical and Experimental , vol.38 , Issue.4 , pp. 387-395
    • DeFronzo, R.A.1    Ferrannini, E.2    Simonson, D.C.3
  • 24
    • 0033995503 scopus 로고    scopus 로고
    • Glucose intolerance is predicted by low insulin secretion and high glucagon secretion: Outcome of a prospective study in postmenopausal Caucasian women
    • Larsson H, Ahrén B. Glucose intolerance is predicted by low insulin secretion and high glucagon secretion: outcome of a prospective study in postmenopausal Caucasian women. Diabetologia 2000;43:194-202 (Pubitemid 30126824)
    • (2000) Diabetologia , vol.43 , Issue.2 , pp. 194-202
    • Larsson, H.1    Ahren, B.2
  • 25
    • 0032877316 scopus 로고    scopus 로고
    • Impact of lack of suppression of glucagon on glucose tolerance in humans
    • Shah P, Basu A, Basu R, Rizza R. Impact of lack of suppression of glucagon on glucose tolerance in humans. Am J Physiol 1999;277:E283-E290
    • (1999) Am J Physiol , vol.277
    • Shah, P.1    Basu, A.2    Basu, R.3    Rizza, R.4
  • 26
    • 34848862525 scopus 로고    scopus 로고
    • Association of fasting glucagon and proinsulin concentrations with insulin resistance
    • Relationship between Insulin Sensitivity and Cardiovascular disease risk (RISC) Project Investigators
    • Ferrannini E, Muscelli E, Natali A, et al.; Relationship between Insulin Sensitivity and Cardiovascular disease risk (RISC) Project Investigators. Association of fasting glucagon and proinsulin concentrations with insulin resistance. Diabetologia 2007;50:2342-2347
    • (2007) Diabetologia , vol.50 , pp. 2342-2347
    • Ferrannini, E.1    Muscelli, E.2    Natali, A.3
  • 28
    • 0033590198 scopus 로고    scopus 로고
    • The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression
    • Woodcroft KJ, Novak RF. The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression. Biochem Biophys Res Commun 1999;266:304-307
    • (1999) Biochem Biophys Res Commun , vol.266 , pp. 304-307
    • Woodcroft, K.J.1    Novak, R.F.2
  • 29
    • 34548389205 scopus 로고    scopus 로고
    • Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans
    • DOI 10.1152/ajpendo.00289.2007
    • Meier JJ, Holst JJ, Schmidt WE, Nauck MA. Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans. Am J Physiol Endocrinol Metab 2007;293:E849-E856 (Pubitemid 47358999)
    • (2007) American Journal of Physiology - Endocrinology and Metabolism , vol.293 , Issue.3
    • Meier, J.J.1    Holst, J.J.2    Schmidt, W.E.3    Nauck, M.A.4
  • 32
    • 20044368667 scopus 로고    scopus 로고
    • Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans
    • DOI 10.2337/diabetes.54.6.1649
    • Meier JJ, Veldhuis JD, Butler PC. Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans. Diabetes 2005;54:1649-1656 (Pubitemid 40770754)
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1649-1656
    • Meier, J.J.1    Veldhuis, J.D.2    Butler, P.C.3
  • 33
    • 0023882507 scopus 로고
    • Dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans
    • Tillil H, Shapiro ET, Miller MA, et al. Dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans. Am J Physiol 1988;254:E349-E357
    • (1988) Am J Physiol , vol.254
    • Tillil, H.1    Shapiro, E.T.2    Miller, M.A.3
  • 34
    • 34447570903 scopus 로고    scopus 로고
    • Beta-cell "rest" accompanies reduced first-pass hepatic insulin extraction in the insulin-resistant, fat-fed canine model
    • Kim SP, Ellmerer M, Kirkman EL, Bergman RN. Beta-cell "rest" accompanies reduced first-pass hepatic insulin extraction in the insulin-resistant, fat-fed canine model. Am J Physiol Endocrinol Metab 2007;292:E1581-E1589
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Kim, S.P.1    Ellmerer, M.2    Kirkman, E.L.3    Bergman, R.N.4
  • 35
    • 0025761974 scopus 로고
    • Cellular trafficking and processing of the insulin receptor
    • Knutson VP. Cellular trafficking and processing of the insulin receptor. FASEB J 1991;5:2130-2138 (Pubitemid 21905845)
    • (1991) FASEB Journal , vol.5 , Issue.8 , pp. 2130-2138
    • Knutson, V.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.