γ-glutamyltransferase, obesity, and the risk of type 2 diabetes: Observational cohort study among 20,158 middle-aged men and women

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 11, 2004, Pages 5410-5414

  Duk, Hee Lee ^a,b   Silventoinen, Karri ^b   Jacobs Jr , David R ^b,d   Jousilahti, Pekka ^c,e   Tuomileto, Jaakko ^c,e  

^a Kyungpook National University School of Medicine   (South Korea)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

^d UNIVERSITY OF OSLO   (Norway)

^e NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA GLUTAMYLTRANSFERASE;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; SEX DIFFERENCE;

ADULT; BODY MASS INDEX; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; MALE; MIDDLE AGED; OBESITY; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 8744291010     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-0505     Document Type: Article

References (29)

1. Nilssen O, Forde OH, Brenn T 1990 The Tromso Study. Distribution and population determinants of γ-glutamyltransferase. Am J Epidemiol 132:318-326
2. Wannamethee G, Ebrahim S, Shaper AG 1995 γ-Glutamyltransferase: determinants and association with mortality from ischemic heart disease and all causes. Am J Epidemiol 142:699-708
3. Brenner H, Rothenbacher D, Arndt V, Schuberth S, Fraisse E, Fliedner TM 1997 Distribution, determinants, and prognostic value of γ- glutamyltransferase for all-cause mortality in a cohort of construction workers from southern Germany. Prev Med 26:305-310
4. Perry IJ, Wannamethee SG, Shaper AG 1998 Prospective study of serum γ-glutamyltransferase and risk of NIDDM. Diabetes Care 21:732-737
5. Miura K, Nakagawa H, Nakamura H, Tabata M, Nagase H, Yoshida M, Kawano S 1994 Serum γ-glutamyl transferase level in predicting hypertension among male drinkers. J Hum Hypertens 8:445-449
6. Jousilahti P, Rastenyte D, Tuomilehto J 2000 Serum γ-glutamyl transferase, self-reported alcohol drinking, and the risk of stroke. Stroke 31:1851-1855
7. Lee DH, Ha MH, Kim JR, Gross M, Jacobs DR 2002 γ- Glutamyltransferase, alcohol, and blood pressure: a four year follow-up study. Ann Epidemiol 12:90-96
8. Lee DH, Ha MH, Kim JH, Christiani DC, Gross MD, Steffes M, Blomhoff R, Jacobs Jr DR 2003 γ-Glutamyltransferase and diabetes - a 4 year follow-up study. Diabetologia 46:359-364
9. Lee DH, Jacobs DR, Gross M, Kiefe CI, Roseman J, Lewis CE, Steffes M 2003 γ-Glutamyltransferase is a predictor of incident diabetes and hypertension: the CARDIA study. Clin Chem 49:1358-1366
10. Teschke R, Brand A, Strohmeyer G 1977 Induction of hepatic microsomal γ-glutamyltransferase activity following chronic alcohol consumption. Biochem Biophys Res Commun 75:718-724
11. Tunstall-Padoe H; WHO MONICA Project 1988 The World Health Organization MONICA Project (monitoring trends and determinants in cardiovascular disease): a major international collaboration. J Clin Epidemiol 41:105-114
12. Vartiainen E, Jousilahti P, Alfthan G, Sundvall J, Pietinen P, Puska P 2000 Cardiovascular risk factor changes in Finland, 1972-1997. Int J Epidemiol 29:49-56
13. Pajak A, Kuulasmaa K, Tuomilehto J, Ruokokoski E 1988 The WHO MONICA Project. Geographical variation in the major risk factors of coronary heart disease in men and women aged 25-64 years. World Health Stat Q 41:115-140
14. SAS Institute, Inc. 1990 SAS/STAT users guide. 4th ed. Cary, NC: SAS Institute, Inc.
15. Vozarova B, Stefan N, Lindsay RS, Saremi A, Pratley RE, Bogardus C, Tataranni PA 2002 High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 51:1889-1895
16. Marchesini G, Brizi M, Blanchi G, Tomassetti S, Bugianesi E, Lenzi M, McCullough AJ, Natale S, Forlani G, Melchionda N 2001 Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 50:1844-1850
17. Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui JM, Fung C, Karim R, Lin R, Samarasinghe D, Liddle C, Weltman M, George J 2002 NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 35:373-379
18. Mehta SH, Brancati FL, Sulkowski MS, Strathdee AS, Szklo M, Thomas DL 2000 Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infections in the United States. Ann Intern Med 17:595-599
19. Custro N, Carroccio A, Ganci A, Scafidi V, Campagna P, Di Prima L, Montalto G 2001 Glycemic homeostasis in chronic viral hepatitis and liver cirrhosis. Diabetes Metab 27:476-481
20. Kugelman A, Choy HA, Liu R, Shi MM, Gozal E, Forman HJ 1994 γ-Glutamyl transpeptidase is increased by oxidative stress in rat alveolar L2 epithelial cells. Am J Respir Cell Mol Biol 11:586-592
21. Takahashi Y, Oakes SM, Williams MC, Takahashi S, Miura T, Joyce-Brady M 1997 Nitrogen dioxide exposure activates γ-glutamyl transferase gene expression in rat lung. Toxicol Appl Pharmacol 143:388-396
22. Karp DR, Shimooku K, Lipsky PE 2001 Expression of γ-glutamyl transpeptidase protects ramos B cells from oxidation-induced cell death. J Biol Chem 276:3798-3804
23. Stark AA 1991 Oxidative metabolism of glutathione by γ-glutamyl transpeptidase and peroxisome proliferation: the relevance to hepatocarcinogenesis. A hypothesis. Mutagenesis 6:241-245
24. Stark AA, Russell JJ, Langenbach R, Pagano DA, Zeiger E, Huberman E 1994 Localization of oxidative damage by a glutathione-γ-glutamyl transpeptidase system in preneoplastic lesions in sections of livers from carcinogen-treated rats. Carcinogenesis 15:343-348
25. Paolicchi A, Tongiani R, Tonarelli P, Comporti M, Pompella A 1997 γ-Glutamyl transpeptidase-dependent lipid peroxidatton in isolated hepatocytes and HepG2 hepatoma cells. Free Radic Biol Med 22:853-860
26. Drozdz R, Parmentier C, Hachad H, Leroy P, Siest G, Wellmart M 1998 γ-Glutamyltransferase dependent generation of reactive oxygen species from a glutathione/transferrin system. Free Radic Biol Med 25:786-792
27. Lee DH, Gross M, Jacobs DR 2004 The association of serum carotenoids and tocopherols with γ-glutamyltransferase: the CARDIA study. Clin Chem 50:582-588
28. Lee DH, Steffen LM, Jacobs DR 2004 Association between serum γ-glutamyltransferase and dietary factors: CARDIA study. Am J Clin Nutr 79:600-605
29. Lee DH, Blomhoff R, Jacobs DR 2004 Is serum γ-glutamyltransferase a marker of oxidative stress? Free Radic Res 38:535-539