Risk factors for incident type 2 diabetes in individuals with a BMI of <27 kg/m2: The role of γ-glutamyltransferase. Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR)

Diabetologia

Volumn 53, Issue 2, 2010, Pages 247-253

  Gautier, A ^a   Balkau, B ^b,c   Lange, C ^b,c   Tichet, J ^d   Bonnet, F ^a,b  

^a SERVICE DE RHUMATOLOGIE   (France)

^b INSERM   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d IRSA   (France)

Author keywords

glutamyltransferase; BMI; Diabetes; Liver; Risk factors

Indexed keywords

ALANINE AMINOTRANSFERASE; BIOLOGICAL MARKER; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; INSULIN;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DIET RESTRICTION; DISEASE ASSOCIATION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN RELEASE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; PROTEIN FUNCTION; RISK FACTOR; WAIST CIRCUMFERENCE;

ADULT; BLOOD GLUCOSE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; EXERCISE; FASTING; FEMALE; FOLLOW-UP STUDIES; FRANCE; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; INCIDENCE; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; OVERWEIGHT; RISK FACTORS; WAIST CIRCUMFERENCE; WEIGHT GAIN;

EID: 77949277852     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1602-6     Document Type: Article

References (31)

1. Edelstein SL, Knowler WC, Bain RP et al (1997) Predictors of progression from impaired glucose tolerance to NIDDM: an analysis of six prospective studies. Diabetes 46:701-710
2. Tuomilehto J, Lindstrom J, Eriksson JG et al (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344: 1343-1350 (Pubitemid 32378388)
3. Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393-403
4. Cicero AF, Dormi A, Nascetti S et al (2005) Relative role of major risk factors for Type 2 diabetes development in the historical cohort of the Brisighella Heart Study: an 8-year follow-up. Diabet Med 22:1263-1266
5. Lorenzo C, Okoloise M, Williams K, Stern MP, Haffner SM (2003) The metabolic syndrome as predictor of type 2 diabetes: the San Antonio Heart Study. Diabetes Care 26:3153-3159
6. Magliano DJ, Barr EL, Zimmet PZ et al (2008) Glucose indices, health behaviors, and incidence of diabetes in Australia: the Australian Diabetes, Obesity and Lifestyle Study. Diabetes Care 31:267-272
7. Bertrais S, Balkau B, Vol S et al (1999) Relationships between abdominal body fat distribution and cardiovascular risk factors: an explanation for women's healthier cardiovascular risk profile. The D.E.S.I.R. Study. Int J Obes Relat Metab Disord 23: 1085-1094
8. Balkau B, Lange C, Fezeu L et al (2008) Predicting diabetes: clinical, biological, and genetic approaches: data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR). Diabetes Care 31:2056-2061
9. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419
10. Hu G, Lindstrom J, Valle TT et al (2004) Physical activity, body mass index, and risk of type 2 diabetes in patients with normal or impaired glucose regulation. Arch Intern Med 164:892-896
11. The Diabetes Prevention Program Research Group (2006) Relationship of body size and shape to the development of diabetes in the diabetes prevention program. Obesity (Silver Spring) 14:2107-2117
12. Andre P, Balkau B, Born C, Charles MA, Eschwege E (2006) Three-year increase of gamma-glutamyltransferase level and development of type 2 diabetes in middle-aged men and women: the D.E.S.I.R. cohort. Diabetologia 49:2599-2603
13. Perry IJ, Wannamethee SG, Shaper AG (1998) Prospective study of serum gamma-glutamyltransferase and risk of NIDDM. Diabetes Care 21:732-737
14. Lee DH, Silventoinen K, Jacobs DR Jr, Jousilahti P, Tuomileto J (2004) gamma-Glutamyltransferase, obesity, and the risk of type 2 diabetes: observational cohort study among 20, 158 middle-aged men and women. J Clin Endocrinol Metab 89:5410-5414
15. Lee DH, Ha MH, Kim JH et al (2003) Gamma-glutamyltransferase and diabetes-a 4 year follow-up study. Diabetologia 46:359-364
16. Nakanishi N, Suzuki K, Tatara K (2004) Serum gammaglutamyltransferase and risk of metabolic syndrome and type 2 diabetes in middle-aged Japanese men. Diabetes Care 27:1427-1432 (Pubitemid 38679993)
17. Wannamethee SG, Shaper AG, Lennon L, Whincup PH (2005) Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men. Diabetes Care 28:2913-2918
18. Sato KK, Hayashi T, Nakamura Y et al (2008) Liver enzymes compared with alcohol consumption in predicting the risk of type 2 diabetes: the Kansai Healthcare Study. Diabetes Care 31:1230-1236
19. Lim JS, Lee DH, Park JY, Jin SH, Jacobs DR Jr (2007) A strong interaction between serum gamma-glutamyltransferase and obesity on the risk of prevalent type 2 diabetes: results from the Third National Health and Nutrition Examination Survey. Clin Chem 53:1092-1098
20. Fraser A, Harris R, Sattar N, Ebrahim S, Davey Smith G, Lawlor DA (2009) Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the BritishWomen's Heart and Health Study and meta-analysis. Diabetes Care 32:741-750
21. Kim CH, Park JY, Lee KU, Kim JH, Kim HK (2009) Association of serum gamma-glutamyltransferase and alanine aminotransferase activities with risk of type 2 diabetes mellitus independent of fatty liver. Diabetes Metab Res Rev 25:64-69
22. Wallace TM, Utzschneider KM, Tong J et al (2007) Relationship of liver enzymes to insulin sensitivity and intra-abdominal fat. Diabetes Care 30:2673-2678
23. Matsuda M, DeFronzo RA (1999) Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22:1462-1470
24. Vozarova B, Stefan N, Lindsay RS et al (2002) High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 51:1889-1895 (Pubitemid 34564303)
25. Lyssenko V, Lupi R, Marchetti P et al (2007) Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest 117:2155-2163
26. Hsiao JY, Wang CL, Hsia PJ et al (2007) Decreased insulin secretion and insulin sensitivity are associated with liver function in subjects with fasting glucose between 100 and 109 mg/dL in Taiwanese population. Pancreas 35:343-347
27. Alvarsson M, Wajngot A, Cerasi E, Efendic S (2005) K-value and low insulin secretion in a non-obese white population: predicted glucose tolerance after 25 years. Diabetologia 48:2262-2268
28. Stancakova A, Javorsky M, Kuulasmaa T, Haffner SM, Kuusisto J, Laakso M (2009) Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men. Diabetes 58:1212-1221
29. Lee DH, Blomhoff R, Jacobs DR Jr (2004) Is serum gamma glutamyltransferase a marker of oxidative stress? Free Radic Res 38:535-539
30. Tang C, Han P, Oprescu AI et al (2007) Evidence for a role of superoxide generation in glucose-induced beta-cell dysfunction in vivo. Diabetes 56:2722-2731
31. Park K, Gross M, Lee DH et al (2009) Oxidative stress and insulin resistance: the coronary artery risk development in young adults study. Diabetes Care 32:1302-1307