메뉴 건너뛰기




Volumn 50, Issue 11, 2007, Pages 2342-2347

Association of fasting glucagon and proinsulin concentrations with insulin resistance

Author keywords

Adiponectin; Alpha cell dysfunction; Beta cell dysfunction; Glucagon; Insulin resistance; Proinsulin

Indexed keywords

C PEPTIDE; GLUCAGON; PROINSULIN;

EID: 34848862525     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-007-0806-x     Document Type: Article
Times cited : (75)

References (27)
  • 1
    • 0023109225 scopus 로고
    • Documentation of hyperglucagonemia throughout the day in nonobese and obese patients with noninsulin-dependent diabetes mellitus
    • Reaven GM, Chen YD, Golay A, Swislocki AL, Jaspan JB (1987) Documentation of hyperglucagonemia throughout the day in nonobese and obese patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 64:106-110
    • (1987) J Clin Endocrinol Metab , vol.64 , pp. 106-110
    • Reaven, G.M.1    Chen, Y.D.2    Golay, A.3    Swislocki, A.L.4    Jaspan, J.B.5
  • 2
    • 0017641399 scopus 로고
    • Immunoreactive glucagon (IRG) responses to intravenous glucose in prediabetes and diabetes among Pima Indians and normal Caucasians
    • Aronoff SL, Bennett PH, Unger RH (1977) Immunoreactive glucagon (IRG) responses to intravenous glucose in prediabetes and diabetes among Pima Indians and normal Caucasians. J Clin Endocrinol Metab 44:968-972
    • (1977) J Clin Endocrinol Metab , vol.44 , pp. 968-972
    • Aronoff, S.L.1    Bennett, P.H.2    Unger, R.H.3
  • 3
    • 0026602267 scopus 로고
    • Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance
    • Mitrakou A, Kelley D, Mokan M et al (1992) Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance. N Engl J Med 326:22-29
    • (1992) N Engl J Med , vol.326 , pp. 22-29
    • Mitrakou, A.1    Kelley, D.2    Mokan, M.3
  • 4
    • 0033126490 scopus 로고    scopus 로고
    • Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo
    • Cherrington AD (1997) Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo. Diabetes 48:1198-1214
    • (1997) Diabetes , vol.48 , pp. 1198-1214
    • Cherrington, A.D.1
  • 5
    • 0034078505 scopus 로고    scopus 로고
    • Islet dysfunction in insulin resistance involves impaired insulin secretion and increased glucagon secretion in postmenopausal women with impaired glucose tolerance
    • Ahrén B, Larsson H (2000) Islet dysfunction in insulin resistance involves impaired insulin secretion and increased glucagon secretion in postmenopausal women with impaired glucose tolerance. Diabetes Care 23:650-657
    • (2000) Diabetes Care , vol.23 , pp. 650-657
    • Ahrén, B.1    Larsson, H.2
  • 6
    • 31444433502 scopus 로고    scopus 로고
    • Glucagon secretion in relation to insulin sensitivity in healthy subjects
    • Ahrén B (2006) Glucagon secretion in relation to insulin sensitivity in healthy subjects. Diabetologia 49:117-122
    • (2006) Diabetologia , vol.49 , pp. 117-122
    • Ahrén, B.1
  • 7
    • 0017761172 scopus 로고
    • Circulating proinsulin in patients with maturity onset diabetes
    • Mako ME, Starr JI, Rubenstein AH (1977) Circulating proinsulin in patients with maturity onset diabetes. Am J Med 63:865-869
    • (1977) Am J Med , vol.63 , pp. 865-869
    • Mako, M.E.1    Starr, J.I.2    Rubenstein, A.H.3
  • 8
    • 0023759449 scopus 로고
    • Serum proinsulin levels at fasting and after oral glucose load in patients with type 2 (non-insulin-dependent) diabetes mellitus
    • Yoshioka N, Kuzuya T, Matsuda A, Taniguchi M, Iwamoto Y (1988) Serum proinsulin levels at fasting and after oral glucose load in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 31:355-360
    • (1988) Diabetologia , vol.31 , pp. 355-360
    • Yoshioka, N.1    Kuzuya, T.2    Matsuda, A.3    Taniguchi, M.4    Iwamoto, Y.5
  • 9
    • 0024463227 scopus 로고
    • Hyperproinsulinemia and amyloid in NIDDM. Clues to etiology of islet beta cell dysfunction?
    • Porte D Jr, Kahn SE (1989) Hyperproinsulinemia and amyloid in NIDDM. Clues to etiology of islet beta cell dysfunction? Diabetes 38:1333-1336
    • (1989) Diabetes , vol.38 , pp. 1333-1336
    • Porte Jr., D.1    Kahn, S.E.2
  • 10
    • 0037447405 scopus 로고    scopus 로고
    • Insulin, proinsulin, proinsulin:insulin ratio, and the risk of developing type 2 diabetes mellitus in women
    • Pradhan AD, Manson JE, Meigs JB et al (2003) Insulin, proinsulin, proinsulin:insulin ratio, and the risk of developing type 2 diabetes mellitus in women. Am J Med 114:438-444
    • (2003) Am J Med , vol.114 , pp. 438-444
    • Pradhan, A.D.1    Manson, J.E.2    Meigs, J.B.3
  • 11
    • 0036230490 scopus 로고    scopus 로고
    • Increased proinsulin levels and decreased acute insulin response independently predict the incidence of type 2 diabetes in the insulin resistance atherosclerosis study
    • Insulin Resistance Atherosclerosis Study
    • Hanley AJ, D'Agostino R Jr, Wagenknecht LE, Saad MF, Savage PJ, Bergman R, Haffner SM; Insulin Resistance Atherosclerosis Study (2002) Increased proinsulin levels and decreased acute insulin response independently predict the incidence of type 2 diabetes in the insulin resistance atherosclerosis study. Diabetes 51:1263-1270
    • (2002) Diabetes , vol.51 , pp. 1263-1270
    • Hanley, A.J.1    D'Agostino Jr., R.2    Wagenknecht, L.E.3    Saad, M.F.4    Savage, P.J.5    Bergman, R.6    Haffner, S.M.7
  • 12
    • 0028230040 scopus 로고
    • What beta cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin processing mechanism
    • Rhodes CJ, Alarcon C (1994) What beta cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin processing mechanism. Diabetes 43:511-517
    • (1994) Diabetes , vol.43 , pp. 511-517
    • Rhodes, C.J.1    Alarcon, C.2
  • 13
    • 0028912883 scopus 로고
    • Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus
    • Alarcon C, Leahy JL, Schuppin GT, Rhodes CJ (1995) Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus. J Clin Invest 95:1032-1039
    • (1995) J Clin Invest , vol.95 , pp. 1032-1039
    • Alarcon, C.1    Leahy, J.L.2    Schuppin, G.T.3    Rhodes, C.J.4
  • 14
    • 1842844418 scopus 로고    scopus 로고
    • The EGIR-RISC study (The European Group for the Study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular Disease Risk): I. Methodology and objectives
    • Hills SA, Balkau B, Coppack SW et al (2004) The EGIR-RISC study (The European Group for the Study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular Disease Risk): I. Methodology and objectives. Diabetologia 47:566-570
    • (2004) Diabetologia , vol.47 , pp. 566-570
    • Hills, S.A.1    Balkau, B.2    Coppack, S.W.3
  • 15
    • 24944545643 scopus 로고    scopus 로고
    • Increased serum adiponectin levels in type 1 diabetic patients with microvascular complications
    • Frystyk J, Tarnow L, Hansen TK, Parving HH, Flyvbjerg A (2005) Increased serum adiponectin levels in type 1 diabetic patients with microvascular complications. Diabetologia 48:1911-1918
    • (2005) Diabetologia , vol.48 , pp. 1911-1918
    • Frystyk, J.1    Tarnow, L.2    Hansen, T.K.3    Parving, H.H.4    Flyvbjerg, A.5
  • 16
    • 0002753305 scopus 로고    scopus 로고
    • Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Suppl 1
    • Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (2000) Diabetes Care 23(Suppl 1):S4-S19
    • (2000) Diabetes Care , vol.23
  • 17
    • 0031846461 scopus 로고    scopus 로고
    • How to measure insulin sensitivity
    • Ferrannini E, Mari A (1998) How to measure insulin sensitivity. J Hypertens 16:895-906
    • (1998) J Hypertens , vol.16 , pp. 895-906
    • Ferrannini, E.1    Mari, A.2
  • 18
    • 26844556580 scopus 로고    scopus 로고
    • Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells
    • Olsen HL, Theander S, Bokvist K, Buschard K, Wollheim CB, Gromada J (2005) Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells. Endocrinology 146:4861-4870
    • (2005) Endocrinology , vol.146 , pp. 4861-4870
    • Olsen, H.L.1    Theander, S.2    Bokvist, K.3    Buschard, K.4    Wollheim, C.B.5    Gromada, J.6
  • 19
    • 33846856711 scopus 로고    scopus 로고
    • Alpha cells of the endocrine pancreas: 35 years of research but the enigma remains
    • Gromada J, Franklin I, Wollheim CB (2007) Alpha cells of the endocrine pancreas: 35 years of research but the enigma remains. Endocr Rev 28:84-116
    • (2007) Endocr Rev , vol.28 , pp. 84-116
    • Gromada, J.1    Franklin, I.2    Wollheim, C.B.3
  • 21
    • 0020046641 scopus 로고
    • Transient hepatic response to glucagon in man: Role of insulin and hyperglycemia
    • Ferrannini E, DeFronzo RA, Sherwin RS (1982) Transient hepatic response to glucagon in man: role of insulin and hyperglycemia. Am J Physiol 242:E73-E81
    • (1982) Am J Physiol , vol.242
    • Ferrannini, E.1    Defronzo, R.A.2    Sherwin, R.S.3
  • 23
    • 0033524937 scopus 로고    scopus 로고
    • Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that of type 2 diabetes
    • Kulkarni RN, Bruning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR (1999) Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that of type 2 diabetes. Cell 96:329-339
    • (1999) Cell , vol.96 , pp. 329-339
    • Kulkarni, R.N.1    Bruning, J.C.2    Winnay, J.N.3    Postic, C.4    Magnuson, M.A.5    Kahn, C.R.6
  • 24
    • 33646351975 scopus 로고    scopus 로고
    • Total insulin and IGF-1 resistance in pancreatic β cells caused overt diabetes
    • Ueki K, Okada T, Hu J, Liew CW et al (2006) Total insulin and IGF-1 resistance in pancreatic β cells caused overt diabetes. Nat Gen 38:583-588
    • (2006) Nat Gen , vol.38 , pp. 583-588
    • Ueki, K.1    Okada, T.2    Hu, J.3    Liew, C.W.4
  • 25
    • 0030884698 scopus 로고    scopus 로고
    • Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR)
    • Ferrannini E, Natali A, Bell P, Cavallo-Perin P, Lalic N, Mingrone G (1997) Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR). J Clin Invest 100:1166-1173
    • (1997) J Clin Invest , vol.100 , pp. 1166-1173
    • Ferrannini, E.1    Natali, A.2    Bell, P.3    Cavallo-Perin, P.4    Lalic, N.5    Mingrone, G.6
  • 26
    • 9444253486 scopus 로고    scopus 로고
    • Beta-cell function in obesity: Effects of weight loss
    • Suppl 3
    • Ferrannini E, Camastra S, Gastaldelli A et al (2004) Beta-cell function in obesity: effects of weight loss. Diabetes 53(Suppl 3):S26-S33
    • (2004) Diabetes , vol.53
    • Ferrannini, E.1    Camastra, S.2    Gastaldelli, A.3
  • 27
    • 33846075221 scopus 로고    scopus 로고
    • Adiposity compared with physical inactivity and risk of type 2 diabetes in women
    • Rana JS, Li TY, Manson JE, Hu FB (2007) Adiposity compared with physical inactivity and risk of type 2 diabetes in women. Diabetes Care 30:53-58
    • (2007) Diabetes Care , vol.30 , pp. 53-58
    • Rana, J.S.1    Li, T.Y.2    Manson, J.E.3    Hu, F.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.