Deletion of a cation transporter promotes lysis in Streptococcus pneumoniae

Infection and Immunity

Volumn 79, Issue 6, 2011, Pages 2314-2323

  Neef, Jolanda ^a,b   Andisi, Vahid Farshchi ^b   Kim, Kwang S ^c   Kuipers, Oscar P ^a   Bijlsma, Jetta J E ^a,b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANTIPORTER; CALCIUM ION; MAGNESIUM CALCIUM EXCHANGE PROTEIN; MAGNESIUM ION; MANGANESE; MEMBRANE PROTEIN; PNEUMOLYSIN; PROTEIN MGTA; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERIOLYSIS; BACTERIUM MUTANT; BLOOD; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STREPTOCOCCUS PNEUMONIAE;

ADENOSINE TRIPHOSPHATASES; BACTERIAL PROTEINS; BLOTTING, WESTERN; CALCIUM; CALCIUM-TRANSPORTING ATPASES; CELL LINE; ENDOTHELIAL CELLS; HUMANS; MAGNESIUM; MEMBRANE TRANSPORT PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SEQUENCE DELETION; STREPTOCOCCUS PNEUMONIAE; STREPTOLYSINS; ZINC;

EID: 79959478930     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00677-10     Document Type: Article

References (53)

1. Bernsel, A., H. Viklund, A. Hennerdal, and A. Elofsson. 2009. TOPCONS: consensus prediction of membrane protein topology. Nucleic Acids Res. 37:W465-W468.
2. Blanc-Potard, A. B., and E. A. Groisman. 1997. The Salmonella selC locus contains a pathogenicity island mediating intramacrophage survival. EMBO J. 16:5376-5385.
3. Blue, C. E., and T. J. Mitchell. 2003. Contribution of a response regulator to the virulence of Streptococcus pneumoniae is strain dependent. Infect. Immun. 71:4405-4413.
4. Chenna, R., et al. 2003. Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 31:3497-3500.
5. Corbino, K. A., et al. 2005. Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria. Genome Biol. 6:R70.
6. Cromie, M. J., Y. Shi, T. Latifi, and E. A. Groisman. 2006. An RNA sensor for intracellular Mg(2+). Cell 125:71-84.
7. Dann, C. E., et al. 2007. Structure and mechanism of a metal-sensing regulatory RNA. Cell 130:878-892.
8. de Ruyter, P. G., O. P. Kuipers, and W. M. de Vos. 1996. Controlled gene expression systems for Lactococcus lactis with the food-grade inducer nisin. Appl. Environ. Microbiol. 62:3662-3667.
9. Derzelle, S., et al. 2004. The PhoP-PhoQ two-component regulatory system of Photorhabdus luminescens is essential for virulence in insects. J. Bacteriol. 186:1270-1279.
10. Elin, R. J. 1987. Assessment of magnesium status. Clin. Chem. 33:1965-1970.
11. Eriksson, S., S. Lucchini, A. Thompson, M. Rhen, and J. C. Hinton. 2003. Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella enterica. Mol. Microbiol. 47:103-118.
12. Filliat, M., C. Galabert, J. P. Chazalette, and A. Dauplan. 1981. Pseudomonas aeruginosa strains and variations of Mg2+ levels in the sputum of patients suffering from different respiratory diseases Monogr. Pediatr. 14: 142-145.
13. Finn, R. D., et al. 2006. Pfam: clans, web tools and services. Nucleic Acids Res. 34:D247-D251.
14. Garcia Véscovi, E., F. C. Soncini, and E. A. Groisman. 1996. Mg2+ as an extracellular signal: environmental regulation of Salmonella virulence. Cell 84:165-174.
15. Grabenstein, J. P., H. S. Fukuto, L. E. Palmer, and J. B. Bliska. 2006. Characterization of phagosome trafficking and identification of PhoP-regulated genes important for survival of Yersinia pestis in macrophages. Infect. Immun. 74:3727-3741.
16. Groisman, E. A. 1998. The ins and outs of virulence gene expression: Mg2+ as a regulatory signal. Bioessays 20:96-101.
17. Groisman, E. A. 2001. The pleiotropic two-component regulatory system PhoP-PhoQ. J. Bacteriol. 183:1835-1842.
18. Gryllos, I., et al. 2007. Mg(2+) signalling defines the group A streptococcal CsrRS (CovRS) regulon. Mol. Microbiol. 65:671-683.
19. Gryllos, I., J. C. Levin, and M. R. Wessels. 2003. The CsrR/CsrS twocomponent system of group A Streptococcus responds to environmental Mg2+. Proc. Natl. Acad. Sci. U. S. A. 100:4227-4232.
20. Halfmann, A., R. Hakenbeck, and R. Bruckner. 2007. A new integrative reporter plasmid for Streptococcus pneumoniae. FEMS Microbiol. Lett. 268: 217-224.
21. Halfmann, A., M. Kovacs, R. Hakenbeck, and R. Bruckner. 2007. Identification of the genes directly controlled by the response regulator CiaR in Streptococcus pneumoniae: five out of 15 promoters drive expression of small non-coding RNAs. Mol. Microbiol. 66:110-126.
22. He, X., et al. 2008. The cia operon of Streptococcus mutans encodes a unique component required for calcium-mediated autoregulation. Mol. Microbiol. 70:112-126.
23. Hmiel, S. P., M. D. Snavely, J. B. Florer, M. E. Maguire, and C. G. Miller. 1989. Magnesium transport in Salmonella typhimurium: genetic characterization and cloning of three magnesium transport loci. J. Bacteriol. 171: 4742-4751.
24. Hoskins, J., et al. 2001. Genome of the bacterium Streptococcus pneumoniae strain R6. J. Bacteriol. 183:5709-5717.
25. Kadioglu, A., et al. 2001. Use of green fluorescent protein in visualisation of pneumococcal invasion of broncho-epithelial cells in vivo. FEMS Microbiol. Lett. 194:105-110.
26. Kilbourn, J. P. 1984. Composition of sputum from patients with cystic fibrosis. Curr. Microbiol. 11:19-22.
27. Kloosterman, T. G., J. J. Bijlsma, J. Kok, and O. P. Kuipers. 2006. To have neighbour's fare: extending the molecular toolbox for Streptococcus pneumoniae. Microbiology 152:351-359.
28. Kloosterman, T. G., M. M. van der Kooi-Pol, J. J. Bijlsma, and O. P. Kuipers. 2007. The novel transcriptional regulator SczA mediates protection against Zn2+ stress by activation of the Zn2+-resistance gene czcD in Streptococcus pneumoniae. Mol. Microbiol. 65:1049-1063.
29. Koedel, U., W. M. Scheld, and H. W. Pfister. 2002. Pathogenesis and pathophysiology of pneumococcal meningitis. Lancet Infect. Dis. 2:721-736.
30. Kouwen, T. R., J. Y. Dubois, R. Freudl, W. J. Quax, and J. M. van Dijl. 2008. Modulation of thiol-disulfide oxidoreductases for increased production of disulfide-bond-containing proteins in Bacillus subtilis. Appl. Environ. Microbiol. 74:7536-7545.
31. Kovacs, M., et al. 2006. A functional dlt operon, encoding proteins required for incorporation of D-alanine in teichoic acids in gram-positive bacteria, confers resistance to cationic antimicrobial peptides in Streptococcus pneumoniae. J. Bacteriol. 188:5797-5805.
32. Kuipers, O., P. de Ruyter, M. Kleerebezem, and W. de Vos. 1998. Quorum sensing-controlled gene expression in lactic acid bacteria. J. Biotechnol. 64:15-21.
33. Lanie, J. A., et al. 2007. Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6. J. Bacteriol. 189:38-51.
34. Lavigne, J. P., D. O'Callaghan, and A. B. Blanc-Potard. 2005. Requirement of MgtC for Brucella suis intramacrophage growth: a potential mechanism shared by Salmonella enterica and Mycobacterium tuberculosis for adaptation to a low-Mg2+ environment. Infect. Immun. 73:3160-3163.
35. Maguire, M. E. 2006. Magnesium transporters: properties, regulation and structure. Front. Biosci. 11:3149-3163.
36. Maguire, M. E., et al. 1992. Mg2+ transporting P-type ATPases of Salmonella typhimurium. Wrong way, wrong place enzymes. Ann. N. Y. Acad. Sci. 671:244-255.
37. Marriott, H. M., T. J. Mitchell, and D. H. Dockrell. 2008. Pneumolysin: a double-edged sword during the host-pathogen interaction. Curr. Mol. Med. 8:497-509.
38. McCluskey, J., J. Hinds, S. Husain, A. Witney, and T. J. Mitchell. 2004. A two-component system that controls the expression of pneumococcal surface antigen A (PsaA) and regulates virulence and resistance to oxidative stress in Streptococcus pneumoniae. Mol. Microbiol. 51:1661-1675.
39. Miller, M., et al. 2010. Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases. PLoS. One 5:e9057.
40. Moncrief, M. B., and M. E. Maguire. 1999. Magnesium transport in prokaryotes. J. Biol. Inorg. Chem. 4:523-527.
41. Obaro, S., and R. Adegbola. 2002. The pneumococcus: carriage, disease and conjugate vaccines. J. Med. Microbiol. 51:98-104.
42. Obert, C., et al. 2006. Identification of a candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease. Infect. Immun. 74:4766-4777.
43. Papp-Wallace, K. M., et al. 2008. The CorA Mg2+ channel is required for the virulence of Salmonella enterica serovar Typhimurium. J. Bacteriol. 190: 6517-6523.
44. Pearce, B. J., F. Iannelli, and G. Pozzi. 2002. Construction of new unencapsulated (rough) strains of Streptococcus pneumoniae. Res. Microbiol. 153: 243-247.
45. Rosch, J. W., J. Sublett, G. Gao, Y. D. Wang, and E. I. Tuomanen. 2008. Calcium efflux is essential for bacterial survival in the eukaryotic host. Mol. Microbiol. 70:435-444.
46. Smith, R. L., L. J. Thompson, and M. E. Maguire. 1995. Cloning and characterization of MgtE, a putative new class of Mg2+ transporter from Bacillus firmus OF4. J. Bacteriol. 177:1233-1238.
47. Snavely, M. D., J. B. Florer, C. G. Miller, and M. E. Maguire. 1989. Magnesium transport in Salmonella typhimurium: 28Mg2+ transport by the CorA, MgtA, and MgtB systems. J. Bacteriol. 171:4761-4766.
48. Song, J. H., et al. 2005. Identification of essential genes in Streptococcus pneumoniae by allelic replacement mutagenesis. Mol. Cells 19:365-374.
49. Stins, M. F., J. Badger, and K. K. Sik. 2001. Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells. Microb. Pathog. 30:19-28.
50. Terzaghi, B. E., and W. E. Sandine. 1975. Improved medium for lactic streptococci and their bacteriophages. Appl. Microbiol. 29:807-813.
51. Tettelin, H., et al. 2001. Complete genome sequence of a virulent isolate of Streptococcus pneumoniae. Science 293:498-506.
52. van Opijnen, T., K. L. Bodi, and A. Camilli. 2009. Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms. Nat. Methods 6:767-772.
53. Vijayakumar, M. N., and D. A. Morrison. 1986. Localization of competenceinduced proteins in Streptococcus pneumoniae. J. Bacteriol. 165:689-695.