Dietary flaxseed administered post thoracic radiation treatment improves survival and mitigates radiation-induced pneumonopathy in mice

BMC Cancer

Volumn 11, Issue , 2011, Pages

  Christofidou Solomidou, Melpo ^a   Tyagi, Sonia ^a   Tan, Kay See ^a   Hagan, Sarah ^a   Pietrofesa, Ralph ^a   Dukes, Floyd ^a   Arguiri, Evguenia ^a   Heitjan, Daniel F ^a   Solomides, Charalambos C ^b   Cengel, Keith A ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

Author keywords

Antioxidant; Bronchoalveolar lavage; Cytokines; Flaxseed; Flaxseed lignans; Inflammation; Lung fibrosis; Lung injury; Mitigation; Mouse model; Radiation pneumonopathy; ROS; SDG; Survival

Indexed keywords

COLLAGEN; CYTOKINE; HYDROXYPROLINE; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; LIGNAN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PROTEIN MIG; UNCLASSIFIED DRUG; VASCULOTROPIN; ANTIOXIDANT; NONSTEROID ANTIINFLAMMATORY AGENT; OXYGEN; PLANT MEDICINAL PRODUCT; RADIOPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD OXYGENATION; CACHEXIA; CALORIC INTAKE; CONTROLLED STUDY; CYTOKINE RELEASE; DIET SUPPLEMENTATION; FEMALE; HISTOPATHOLOGY; INFLAMMATORY INFILTRATE; LINSEED; LUNG DISEASE; LUNG FIBROSIS; LUNG HEMODYNAMICS; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; NONHUMAN; PARTIAL BODY RADIATION; PNEUMONIA; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INDUCED PNEUMONOPATHY; RADIATION INJURY; RADIATION PROTECTION; SURVIVAL RATE; THORAX RADIOTHERAPY; TISSUE LEVEL; WEIGHT REDUCTION; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; COMPARATIVE STUDY; DIET; DIET THERAPY; DRUG SCREENING; FLAX; LUNG; OXIDATIVE STRESS; PATHOLOGY; PHYTOTHERAPY; PLANT SEED; RADIATION PNEUMONIA; RADIOTHERAPY; RANDOMIZATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; BRONCHOALVEOLAR LAVAGE FLUID; CACHEXIA; CYTOKINES; DIET; DRUG EVALUATION, PRECLINICAL; FEMALE; FLAX; LIGNANS; LUNG; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; OXYGEN; PHYTOTHERAPY; PLANT PREPARATIONS; PULMONARY FIBROSIS; RADIATION PNEUMONITIS; RADIATION-PROTECTIVE AGENTS; RADIOTHERAPY; RANDOM ALLOCATION; SEEDS; WEIGHT LOSS;

EID: 79959452606     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-269     Document Type: Article

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