A high-throughput fluorescence resonance energy transfer-based assay for DNA ligase

Journal of Biomolecular Screening

Volumn 16, Issue 5, 2011, Pages 486-493

  Shapiro, Adam B ^a   Eakin, Ann E ^a   Walkup, Grant K ^a   Rivin, Olga ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

DNA ligase; fluorescence resonance energy transfer; FRET; high throughput screening

Indexed keywords

DEOXYRIBONUCLEIC ACID LIGASE INHIBITOR; ENZYME INHIBITOR; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DETERMINATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HAEMOPHILUS INFLUENZAE; HIGH THROUGHPUT SCREENING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; DNA; DNA LIGASES; DRUG DISCOVERY; ENZYME INHIBITORS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HAEMOPHILUS INFLUENZAE; HIGH-THROUGHPUT SCREENING ASSAYS; KINETICS; NAD;

HAEMOPHILUS INFLUENZAE;

EID: 79959441831     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111398295     Document Type: Article

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