Improving memory and decreasing cognitive impairment in Tg-APPswe/PSEN1dE9 mice with Aβ3-10 repeat fragment plasmid by reducing Aβ deposition and inflammatory response

Brain Research

Volumn 1400, Issue , 2011, Pages 112-124

  Ma, Ying ^a   Li, Yu ^a   Zong, Li Xia ^a   Xing, Xiao Na ^a   Zhang, Wei Ge ^a   Cao, Yun Peng ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Amyloid beta protein; Astrocytes; Behavior; Immunotherapy; Inflammatory response

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CYTOKINE; DNA VACCINE; GAMMA INTERFERON; INTERLEUKIN 4; PLASMID DNA;

ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY DETECTION; ARTICLE; ASTROCYTE; BLOOD LEVEL; BRAIN LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPUS; IMMUNIZATION; IMMUNOGENICITY; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; INFLAMMATION; MAZE TEST; MEMORY; MOUSE; NONHUMAN; PLASMA; PRIORITY JOURNAL; TRANSGENIC MOUSE; TREATMENT OUTCOME; URINALYSIS;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIBODIES; ASTROCYTES; BRAIN; COGNITION DISORDERS; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLIAL FIBRILLARY ACIDIC PROTEIN; INFLAMMATION; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID; PRESENILIN-1; REPETITIVE SEQUENCES, NUCLEIC ACID;

MUS;

EID: 79959373338     PISSN: 00068993     EISSN: 00068993     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.05.030     Document Type: Article

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