-
1
-
-
0037427972
-
The superfamily of organic anion transporting polypeptides
-
DOI 10.1016/S0005-2736(02)00633-8, PII S0005273602006338
-
Hagenbuch, B. & Meier, P.J. The superfamily of organic anion transporting polypeptides. Biochim. Biophys. Acta 1609, 1-18 (2003). (Pubitemid 36044060)
-
(2003)
Biochimica et Biophysica Acta - Biomembranes
, vol.1609
, Issue.1
, pp. 1-18
-
-
Hagenbuch, B.1
Meier, P.J.2
-
2
-
-
33645110538
-
Pharmacogenomics of human OATP transporters
-
Konig, J., Seithel, A., Gradhand, U. & Fromm, M.F. Pharmacogenomics of human OATP transporters. Naunyn Schmiedebergs Arch. Pharmacol. 372, 432-443 (2006).
-
(2006)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.372
, pp. 432-443
-
-
Konig, J.1
Seithel, A.2
Gradhand, U.3
Fromm, M.F.4
-
3
-
-
56149110125
-
Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs
-
Maeda, K. & Sugiyama, Y. Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs. Drug Metab. Pharmacokinet. 23, 223-235 (2008).
-
(2008)
Drug Metab. Pharmacokinet.
, vol.23
, pp. 223-235
-
-
Maeda, K.1
Sugiyama, Y.2
-
4
-
-
0035125407
-
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver
-
Kullak-Ublick, G.A. et al. Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology 120, 525-533 (2001). (Pubitemid 32147650)
-
(2001)
Gastroenterology
, vol.120
, Issue.2
, pp. 525-533
-
-
Kullak-Ublick, G.A.1
Ismair, M.G.2
Stieger, B.3
Landmann, L.4
Huber, R.5
Pizzagalli, F.6
Fattinger, K.7
Meier, P.J.8
Hagenbuch, B.9
-
5
-
-
65649132986
-
Pharmacogenetics of the organic anion transporting polypeptide 1A2
-
Franke, R.M., Scherkenbach, L.A. & Sparreboom, A. Pharmacogenetics of the organic anion transporting polypeptide 1A2. Pharmacogenomics 10, 339-344 (2009).
-
(2009)
Pharmacogenomics
, vol.10
, pp. 339-344
-
-
Franke, R.M.1
Scherkenbach, L.A.2
Sparreboom, A.3
-
6
-
-
0029091022
-
Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver
-
Kullak-Ublick, G.A. et al. Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver. Gastroenterology 109, 1274-1282 (1995).
-
(1995)
Gastroenterology
, vol.109
, pp. 1274-1282
-
-
Kullak-Ublick, G.A.1
-
7
-
-
15744367808
-
Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): Implications for altered drug disposition and central nervous system drug entry
-
DOI 10.1074/jbc.M411092200
-
Lee, W. et al. Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry. J. Biol. Chem. 280, 9610-9617 (2005). (Pubitemid 40409657)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.10
, pp. 9610-9617
-
-
Lee, W.1
Glaeser, H.2
Smith, L.H.3
Roberts, R.L.4
Moeckel, G.W.5
Gervasini, G.6
Leake, B.F.7
Kim, R.B.8
-
8
-
-
33745953360
-
Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants
-
DOI 10.1124/jpet.106.104364
-
Badagnani, I. et al. Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants. J. Pharmacol. Exp. Ther. 318, 521-529 (2006). (Pubitemid 44061225)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.318
, Issue.2
, pp. 521-529
-
-
Badagnani, I.1
Castro, R.A.2
Taylor, T.R.3
Brett, C.M.4
Huang, C.C.5
Stryke, D.6
Kawamoto, M.7
Johns, S.J.8
Ferrin, T.E.9
Carlson, E.J.10
Burchard, E.G.11
Giacomini, K.M.12
-
9
-
-
75649091119
-
HIV protease inhibitors are substrates for OATP1A2 OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms
-
Hartkoorn, R.C. et al. HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms. Pharmacogenet. Genomics 20, 112-120 (2010).
-
(2010)
Pharmacogenet. Genomics
, vol.20
, pp. 112-120
-
-
Hartkoorn, R.C.1
-
10
-
-
0036094117
-
Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia
-
Cohen, M.H. et al. Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia. Clin. Cancer Res. 8, 935-942 (2002). (Pubitemid 34520420)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.5
, pp. 935-942
-
-
Cohen, M.H.1
Williams, G.2
Johnson, J.R.3
Duan, J.4
Gobburu, J.5
Rahman, A.6
Benson, K.7
Leighton, J.8
Kim, S.K.9
Wood, R.10
Rothmann, M.11
Chen, G.12
U, K.M.13
Staten, A.M.14
Pazdur, R.15
-
11
-
-
0036795899
-
Approval summary: Imatinib mesylate in the treatment of metastatic and/or unresectable malignant gastrointestinal stromal tumors
-
Dagher, R. et al. Approval summary: imatinib mesylate in the treatment of metastatic and/or unresectable malignant gastrointestinal stromal tumors. Clin. Cancer Res. 8, 3034-3038 (2002). (Pubitemid 35155011)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.10
, pp. 3034-3038
-
-
Dagher, R.1
Cohen, M.2
Williams, G.3
Rothmann, M.4
Gobburu, J.5
Robbie, G.6
Rahman, A.7
Chen, G.8
Staten, A.9
Griebel, D.10
Pazdur, R.11
-
12
-
-
24344482346
-
Clinical pharmacokinetics of imatinib
-
DOI 10.2165/00003088-200544090-00001
-
Peng, B., Lloyd, P. & Schran, H. Clinical pharmacokinetics of imatinib. Clin. Pharmacokinet. 44, 879-894 (2005). (Pubitemid 41252840)
-
(2005)
Clinical Pharmacokinetics
, vol.44
, Issue.9
, pp. 879-894
-
-
Peng, B.1
Lloyd, P.2
Schran, H.3
-
13
-
-
34147174980
-
Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia
-
DOI 10.1182/blood-2006-07-036012
-
Picard, S. et al. Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia. Blood 109, 3496-3499 (2007). (Pubitemid 46572540)
-
(2007)
Blood
, vol.109
, Issue.8
, pp. 3496-3499
-
-
Picard, S.1
Titier, K.2
Etienne, G.3
Teilhet, E.4
Ducint, D.5
Bernard, M.-A.6
Lassalle, R.7
Marit, G.8
Reiffers, J.9
Begaud, B.10
Moore, N.11
Molimard, M.12
Mahon, F.-X.13
-
14
-
-
43249083718
-
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: A subanalysis of the IRIS study
-
IRIS (International Randomized Interferon vs STI571) Study Group
-
Larson, R.A. et al.; IRIS (International Randomized Interferon vs STI571) Study Group. Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study. Blood 111, 4022-4028 (2008).
-
(2008)
Blood
, vol.111
, pp. 4022-4028
-
-
Larson, R.A.1
-
15
-
-
9444282642
-
Active transport of imatinib into and out of cells: Implications for drug resistance
-
DOI 10.1182/blood-2003-12-4276
-
Thomas, J., Wang, L., Clark, R.E. & Pirmohamed, M. Active transport of imatinib into and out of cells: implications for drug resistance. Blood 104, 3739-3745 (2004). (Pubitemid 39564452)
-
(2004)
Blood
, vol.104
, Issue.12
, pp. 3739-3745
-
-
Thomas, J.1
Wang, L.2
Clark, R.E.3
Pirmohamed, M.4
-
16
-
-
49649092002
-
Interaction of imatinib with human organic ion carriers
-
Hu, S. et al. Interaction of imatinib with human organic ion carriers. Clin. Cancer Res. 14, 3141-3148 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3141-3148
-
-
Hu, S.1
-
17
-
-
51649092790
-
Inhibition of imatinib transport by uremic toxins during renal failure
-
author reply 4227, 2008
-
Franke, R.M. & Sparreboom, A. Inhibition of imatinib transport by uremic toxins during renal failure. J. Clin. Oncol. 26, 4226-4227; author reply 4227 (2008).
-
J. Clin. Oncol.
, vol.26
, pp. 4226-4227
-
-
Franke, R.M.1
Sparreboom, A.2
-
18
-
-
31044455564
-
Variation of flavonoids and furanocoumarins in grapefruit juices: A potential source of variability in grapefruit juice-drug interaction studies
-
DOI 10.1021/jf0516944
-
De Castro, W.V., Mertens-Talcott, S., Rubner, A., Butterweck, V. & Derendorf, H. Variation of flavonoids and furanocoumarins in grapefruit juices: a potential source of variability in grapefruit juice-drug interaction studies. J. Agric. Food Chem. 54, 249-255 (2006). (Pubitemid 43119947)
-
(2006)
Journal of Agricultural and Food Chemistry
, vol.54
, Issue.1
, pp. 249-255
-
-
De Castro, W.V.1
Mertens-Talcott, S.2
Rubner, A.3
Butterweck, V.4
Derendorf, H.5
-
19
-
-
33947420519
-
Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice
-
DOI 10.1038/sj.clpt.6100104, PII 6100104
-
Bailey, D.G., Dresser, G.K., Leake, B.F. & Kim, R.B. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin. Pharmacol. Ther. 81, 495-502 (2007). (Pubitemid 46452308)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.81
, Issue.4
, pp. 495-502
-
-
Bailey, D.G.1
Dresser, G.K.2
Leake, B.F.3
Kim, R.B.4
-
20
-
-
34047170808
-
Regional distribution of solute carrier mRNA expression along the human intestinal tract
-
DOI 10.1124/dmd.106.013342
-
Meier, Y. et al. Regional distribution of solute carrier mRNA expression along the human intestinal tract. Drug Metab. Dispos. 35, 590-594 (2007). (Pubitemid 46513261)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.4
, pp. 590-594
-
-
Meier, Y.1
Eloranta, J.J.2
Darimont, J.3
Ismair, M.G.4
Hiller, C.5
Fried, M.6
Kullak-Ublick, G.A.7
Vavricka, S.R.8
-
21
-
-
33847662941
-
Intestinal drug transporter expression and the impact of grapefruit juice in humans
-
DOI 10.1038/sj.clpt.6100056, PII 6100056
-
Glaeser, H. et al. Intestinal drug transporter expression and the impact of grapefruit juice in humans. Clin. Pharmacol. Ther. 81, 362-370 (2007). (Pubitemid 46364477)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.81
, Issue.3
, pp. 362-370
-
-
Glaeser, H.1
Bailey, D.G.2
Dresser, G.K.3
Gregor, J.C.4
Schwarz, U.I.5
McGrath, J.S.6
Jolicoeur, E.7
Lee, W.8
Leake, B.F.9
Tirona, R.G.10
Kim, R.B.11
-
22
-
-
0032513049
-
Dehydroepiandrosterone sulfate (DHEAS): Identification of a carrier protein in human liver and brain
-
Kullak-Ublick, G.A. et al. Dehydroepiandrosterone sulfate (DHEAS): identification of a carrier protein in human liver and brain. FEBS Lett. 424, 173-176 (1998).
-
(1998)
FEBS Lett.
, vol.424
, pp. 173-176
-
-
Kullak-Ublick, G.A.1
-
23
-
-
33745085275
-
OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): Reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib
-
DOI 10.1182/blood-2005-11-4687
-
White, D.L. et al. OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib. Blood 108, 697-704 (2006). (Pubitemid 44061372)
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 697-704
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
Engler, J.4
Zannettino, A.C.W.5
Cambareri, A.C.6
Quinn, S.R.7
Manley, P.W.8
Hughes, T.P.9
-
24
-
-
38349193809
-
Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia
-
Wang, L., Giannoudis, A., Lane, S., Williamson, P., Pirmohamed, M. & Clark, R.E. Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia. Clin. Pharmacol. Ther. 83, 258-264 (2008).
-
(2008)
Clin. Pharmacol. Ther.
, vol.83
, pp. 258-264
-
-
Wang, L.1
Giannoudis, A.2
Lane, S.3
Williamson, P.4
Pirmohamed, M.5
Clark, R.E.6
-
25
-
-
0035211396
-
Catalog of 258 single-nucleotide polymorphisms (SNPs) in genes encoding three organic anion transporters, three organic anion-transporting polypeptides, and three NADH:ubiquinone oxidoreductase flavoproteins
-
DOI 10.1007/s100380170019
-
Iida, A. et al. Catalog of 258 single-nucleotide polymorphisms (SNPs) in genes encoding three organic anion transporters, three organic anion-transporting polypeptides, and three NADH:ubiquinone oxidoreductase flavoproteins. J. Hum. Genet. 46, 668-683 (2001). (Pubitemid 33134745)
-
(2001)
Journal of Human Genetics
, vol.46
, Issue.11
, pp. 668-683
-
-
Iida, A.1
Saito, S.2
Sekine, A.3
Mishima, C.4
Kondo, K.5
Kitamura, Y.6
Harigae, S.7
Osawa, S.8
Nakamura, Y.9
-
26
-
-
67749101106
-
Relationship between an effective dose of imatinib, body surface area, and trough drug levels in patients with chronic myeloid leukemia
-
Kawaguchi, T. et al. Relationship between an effective dose of imatinib, body surface area, and trough drug levels in patients with chronic myeloid leukemia. Int. J. Hematol. 89, 642-648 (2009).
-
(2009)
Int. J. Hematol.
, vol.89
, pp. 642-648
-
-
Kawaguchi, T.1
-
27
-
-
0036159433
-
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine
-
DOI 10.1067/mcp.2002.121152
-
Dresser, G.K. et al. Fruit juices inhibit organic anion transporting polypeptidemediated drug uptake to decrease the oral availability of fexofenadine. Clin. Pharmacol. Ther. 71, 11-20 (2002). (Pubitemid 34124034)
-
(2002)
Clinical Pharmacology and Therapeutics
, vol.71
, Issue.1
, pp. 11-20
-
-
Dresser, G.K.1
Bailey, D.G.2
Leake, B.F.3
Schwarz, U.I.4
Dawson, P.A.5
Freeman, D.J.6
Kim, R.B.7
-
28
-
-
0032793959
-
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
-
Cvetkovic, M., Leake, B., Fromm, M.F., Wilkinson, G.R. & Kim, R.B. OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. Drug Metab. Dispos. 27, 866-871 (1999). (Pubitemid 29347585)
-
(1999)
Drug Metabolism and Disposition
, vol.27
, Issue.8
, pp. 866-871
-
-
Cvetkovic, M.1
Leake, B.2
Fromm, M.F.3
Wilkinson, G.R.4
Kim, R.B.5
-
29
-
-
13944275994
-
Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: Possible role of organic anion transporting polypeptides
-
DOI 10.1016/j.clpt.2004.10.005
-
Dresser, G.K., Kim, R.B. & Bailey, D.G. Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides. Clin. Pharmacol. Ther. 77, 170-177 (2005). (Pubitemid 40269132)
-
(2005)
Clinical Pharmacology and Therapeutics
, vol.77
, Issue.3
, pp. 170-177
-
-
Dresser, G.K.1
Kim, R.B.2
Bailey, D.G.3
-
30
-
-
77957337144
-
Intestinal absorption of HMGCoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide
-
Shirasaka, Y., Suzuki, K., Nakanishi, T. & Tamai, I. Intestinal absorption of HMGCoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide. Pharm. Res. 27, 2141-2149 (2010).
-
(2010)
Pharm. Res.
, vol.27
, pp. 2141-2149
-
-
Shirasaka, Y.1
Suzuki, K.2
Nakanishi, T.3
Tamai, I.4
-
31
-
-
34250676807
-
Imatinib disposition and ABCB1 (MDR1, P-glycoprotein) genotype
-
DOI 10.1038/sj.clpt.6100201, PII 6100201
-
Gurney, H. et al. Imatinib disposition and ABCB1 (MDR1, P-glycoprotein) genotype. Clin. Pharmacol. Ther. 82, 33-40 (2007). (Pubitemid 46944197)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.82
, Issue.1
, pp. 33-40
-
-
Gurney, H.1
Wong, M.2
Balleine, R.L.3
Rivory, L.P.4
McLachlan, A.J.5
Hoskins, J.M.6
Wilcken, N.7
Clarke, C.L.8
Mann, G.J.9
Collins, M.10
Delforce, S.-E.11
Lynch, K.12
Schran, H.13
-
32
-
-
52649177063
-
Multidrug resistance gene (MDR1) polymorphisms are associated with major molecular responses to standard-dose imatinib in chronic myeloid leukemia
-
Dulucq, S. et al. Multidrug resistance gene (MDR1) polymorphisms are associated with major molecular responses to standard-dose imatinib in chronic myeloid leukemia. Blood 112, 2024-2027 (2008).
-
(2008)
Blood
, vol.112
, pp. 2024-2027
-
-
Dulucq, S.1
-
33
-
-
79953183550
-
Association of genetic polymorphisms in the influx transporter SLCO1B3 and the efflux transporter ABCB1 with imatinib pharmacokinetics in patients with chronic myeloid leukemia
-
Y amakawa, Y. et al. Association of genetic polymorphisms in the influx transporter SLCO1B3 and the efflux transporter ABCB1 with imatinib pharmacokinetics in patients with chronic myeloid leukemia. Ther. Drug Monit. 33, 244-250 (2011).
-
(2011)
Ther. Drug Monit.
, vol.33
, pp. 244-250
-
-
Yamakawa, Y.1
-
34
-
-
78649522748
-
Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia
-
Takahashi, N. et al. Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia. J. Hum. Genet. 55, 731-737 (2010).
-
(2010)
J. Hum. Genet.
, vol.55
, pp. 731-737
-
-
Takahashi, N.1
-
35
-
-
0142241268
-
Interaction of imatinib mesilate with human P-glycoprotein
-
DOI 10.1124/jpet.103.055574
-
Hamada, A., Miyano, H., Watanabe, H. & Saito, H. Interaction of imatinib mesilate with human P-glycoprotein. J. Pharmacol. Exp. Ther. 307, 824-828 (2003). (Pubitemid 37310701)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.307
, Issue.2
, pp. 824-828
-
-
Hamada, A.1
Miyano, H.2
Watanabe, H.3
Saito, H.4
-
36
-
-
20144364602
-
Imatinib pharmacokinetics in patients with gastrointestinal stromal tumour: A retrospective population pharmacokinetic study over time. EORTC Soft Tissue and Bone Sarcoma Group
-
DOI 10.1007/s00280-004-0876-0
-
J udson, I. et al. Imatinib pharmacokinetics in patients with gastrointestinal stromal tumour: a retrospective population pharmacokinetic study over time. EORTC Soft Tissue and Bone Sarcoma Group. Cancer Chemother. Pharmacol. 55, 379-386 (2005). (Pubitemid 40379262)
-
(2005)
Cancer Chemotherapy and Pharmacology
, vol.55
, Issue.4
, pp. 379-386
-
-
Judson, I.1
Ma, P.2
Peng, B.3
Verweij, J.4
Racine, A.5
Di Paola, E.D.6
Van Glabbeke, M.7
Dimitrijevic, S.8
Scurr, M.9
Dumez, H.10
Van Oosterom, A.11
|