Neuroprotective effects of citidine-5-diphosphocholine on impaired spatial memory in a rat model of cerebrovascular dementia

Journal of Pharmacological Sciences

Volumn 116, Issue 2, 2011, Pages 232-237

  Takasaki, Kotaro ^a   Uchida, Kanako ^a   Fujikawa, Risako ^a   Nogami, Ai ^a   Nakamura, Kazuya ^a   Kawasaki, Chihiro ^a   Yamaguchi, Kazuko ^a   Morita, Masahiko ^b   Morishita, Koji ^b   Kubota, Kaori ^a   Katsurabayashi, Shutaro ^a   Mishima, Kenichi ^a   Fujiwara, Michihiro ^a   Iwasaki, Katsunori ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b Kyowa Hakko Bio Co   (Japan)

Author keywords

Apoptosis; Citidine 5 diphosphocholine (CDP choline); Repeated ischemia; Spatial memory

Indexed keywords

CASPASE 3; CITICOLINE; COGNIZIN; DONEPEZIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; HIPPOCAMPAL CA1 REGION; MALE; MAZE TEST; MEMORY DISORDER; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; RAT; SPATIAL MEMORY;

EID: 79959369914     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.11013FP     Document Type: Article

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