-
1
-
-
79959327162
-
-
Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. Available at: (accessed 1 September 2010).
-
Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. Available at: (accessed 1 September 2010).
-
-
-
-
2
-
-
5144221336
-
Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma Control study
-
Bateman ED, Boushey HA, Bousquet J, etal. Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma Control study. Am J Respir Crit Care Med. 2004;170: 836-44.
-
(2004)
Am J Respir Crit Care Med.
, vol.170
, pp. 836-844
-
-
Bateman, E.D.1
Boushey, H.A.2
Bousquet, J.3
-
3
-
-
77949265937
-
Overall asthma control: the relationship between current control and future risk
-
Bateman ED, Reddel HK, Eriksson G, etal. Overall asthma control: the relationship between current control and future risk. J Allergy Clin Immunol. 2010;125: 600-8.
-
(2010)
J Allergy Clin Immunol.
, vol.125
, pp. 600-608
-
-
Bateman, E.D.1
Reddel, H.K.2
Eriksson, G.3
-
4
-
-
36849000336
-
Asthma control in Europe: a real-world evaluation based on an international population-based study
-
Cazzoletti L, Marcon A, Janson C, etal. Asthma control in Europe: a real-world evaluation based on an international population-based study. J Allergy Clin Immunol. 2007;120: 1360-7.
-
(2007)
J Allergy Clin Immunol.
, vol.120
, pp. 1360-1367
-
-
Cazzoletti, L.1
Marcon, A.2
Janson, C.3
-
6
-
-
70349878828
-
The role of small airways in monitoring the response to asthma treatment: what is beyond FEV1?
-
Scichilone N, Battaglia S, Olivieri D, Bellia V. The role of small airways in monitoring the response to asthma treatment: what is beyond FEV1? Allergy. 2009;64: 1563-9.
-
(2009)
Allergy.
, vol.64
, pp. 1563-1569
-
-
Scichilone, N.1
Battaglia, S.2
Olivieri, D.3
Bellia, V.4
-
7
-
-
34248547426
-
Differential anti-inflammatory effects of large and small particle size inhaled corticosteroids in asthma
-
Menzies D, Nair A, Hopkinson L, etal. Differential anti-inflammatory effects of large and small particle size inhaled corticosteroids in asthma. Allergy. 2007;62: 661-7.
-
(2007)
Allergy.
, vol.62
, pp. 661-667
-
-
Menzies, D.1
Nair, A.2
Hopkinson, L.3
-
8
-
-
0036036475
-
Lung deposition of hydrofluoroalkane-134a beclomethasone is greater than that of chlorofluorocarbon fluticasone and chlorofluorocarbon beclomethasone: a cross over study in health volunteers
-
Leach CL, Davidson PJ, Hasselquist BE, Boudreau RJ. Lung deposition of hydrofluoroalkane-134a beclomethasone is greater than that of chlorofluorocarbon fluticasone and chlorofluorocarbon beclomethasone: a cross over study in health volunteers. Chest. 2002;122: 510-6.
-
(2002)
Chest.
, vol.122
, pp. 510-516
-
-
Leach, C.L.1
Davidson, P.J.2
Hasselquist, B.E.3
Boudreau, R.J.4
-
9
-
-
0037371538
-
Influence of particle size on lung deposition and pharmacokinetics of beclomethasone dipropionate in children
-
Agertoft L, Laulund LW, Harrison LI, Pedersen S. Influence of particle size on lung deposition and pharmacokinetics of beclomethasone dipropionate in children. Pediatr Pulmonol. 2003;35: 192-9.
-
(2003)
Pediatr Pulmonol.
, vol.35
, pp. 192-199
-
-
Agertoft, L.1
Laulund, L.W.2
Harrison, L.I.3
Pedersen, S.4
-
10
-
-
0032438394
-
Improved airway targeting with the CFC-free HFA beclomethasone metered-dose inhaler compared with CFC-beclomethasone
-
Leach CL, Davidson PJ, Boudreau RJ. Improved airway targeting with the CFC-free HFA beclomethasone metered-dose inhaler compared with CFC-beclomethasone. Eur Respir J. 1998;12: 1346-53.
-
(1998)
Eur Respir J.
, vol.12
, pp. 1346-1353
-
-
Leach, C.L.1
Davidson, P.J.2
Boudreau, R.J.3
-
11
-
-
0033408351
-
Effect of formulation parameters on hydrofluoroalkane-beclomethasone dipropionate drug deposition in humans
-
Leach C. Effect of formulation parameters on hydrofluoroalkane-beclomethasone dipropionate drug deposition in humans. J Allergy Clin Immunol. 1999;104: S250-2.
-
(1999)
J Allergy Clin Immunol.
, vol.104
-
-
Leach, C.1
-
12
-
-
33745601984
-
Two-dimensional and three-dimensional imaging show ciclosonide had high lung deposition and peripheral distribution: a non-randomized study in healthy volunteers
-
Leach CL, Bethke TD, Boudreau RJ, etal. Two-dimensional and three-dimensional imaging show ciclosonide had high lung deposition and peripheral distribution: a non-randomized study in healthy volunteers. J Aerosol Med. 2006;19: 117-26.
-
(2006)
J Aerosol Med.
, vol.19
, pp. 117-126
-
-
Leach, C.L.1
Bethke, T.D.2
Boudreau, R.J.3
-
14
-
-
33749360241
-
Subpollen particles: carrier of allergenic proteins and oxidases
-
Bacsi A, Choudhury BK, Dharajiya N, etal. Subpollen particles: carrier of allergenic proteins and oxidases. J Allergy Clin Immunol. 2006;18: 844-50.
-
(2006)
J Allergy Clin Immunol.
, vol.18
, pp. 844-850
-
-
Bacsi, A.1
Choudhury, B.K.2
Dharajiya, N.3
-
15
-
-
0029845201
-
Glucocorticoid receptor localization in normal and asthmatic lung
-
Adcock IM, Gilbey T, Gelder CM, etal. Glucocorticoid receptor localization in normal and asthmatic lung. Am J Respir Crit Care Med. 1996;154: 771-82.
-
(1996)
Am J Respir Crit Care Med.
, vol.154
, pp. 771-782
-
-
Adcock, I.M.1
Gilbey, T.2
Gelder, C.M.3
-
16
-
-
0025332174
-
Peripheral lung resistance in normal and asthmatic subjects
-
Wagner EM, Liu MC, Weinmann GG, etal. Peripheral lung resistance in normal and asthmatic subjects. Am Rev Respir Dis. 1990;148: 584-8.
-
(1990)
Am Rev Respir Dis.
, vol.148
, pp. 584-588
-
-
Wagner, E.M.1
Liu, M.C.2
Weinmann, G.G.3
-
17
-
-
0030055306
-
Cellular infiltration of the airways of asthma of varying severity
-
Synek M, Beasley R, Frew AJ, etal. Cellular infiltration of the airways of asthma of varying severity. Am J Respir Crit Care Med. 1996;153: 224-30.
-
(1996)
Am J Respir Crit Care Med.
, vol.153
, pp. 224-230
-
-
Synek, M.1
Beasley, R.2
Frew, A.J.3
-
18
-
-
0034952788
-
Distal lung dysfunction at night in nocturnal asthma
-
Kraft M, Pak J, Martin RJ, etal. Distal lung dysfunction at night in nocturnal asthma. Am J Respir Crit Care Med. 2001;163: 1551-6.
-
(2001)
Am J Respir Crit Care Med.
, vol.163
, pp. 1551-1556
-
-
Kraft, M.1
Pak, J.2
Martin, R.J.3
-
19
-
-
34548484562
-
Beclomethasone/formoterol vs. fluticasone/salmeterol inhaled combination in moderate to severe asthma
-
Papi A, Paggiaro P, Nicolini G, etal. Beclomethasone/formoterol vs. fluticasone/salmeterol inhaled combination in moderate to severe asthma. Allergy. 2007;62: 1182-8.
-
(2007)
Allergy.
, vol.62
, pp. 1182-1188
-
-
Papi, A.1
Paggiaro, P.2
Nicolini, G.3
-
20
-
-
7044270909
-
Oscillation mechanics of the human lung periphery in asthma
-
Kaminsky DA, Irvin CG, Lundblad L, etal. Oscillation mechanics of the human lung periphery in asthma. J Appl Physiol. 2004;97: 1849-58.
-
(2004)
J Appl Physiol.
, vol.97
, pp. 1849-1858
-
-
Kaminsky, D.A.1
Irvin, C.G.2
Lundblad, L.3
-
21
-
-
33644902403
-
Nitrogen washout slope in poorly controlled asthma
-
Bourdin A, Paganin F, Prefaut C, etal. Nitrogen washout slope in poorly controlled asthma. Allergy. 2006;61: 85-9.
-
(2006)
Allergy.
, vol.61
, pp. 85-89
-
-
Bourdin, A.1
Paganin, F.2
Prefaut, C.3
-
22
-
-
33645937013
-
Effects of hydrofluoroalkane and dry powder-formulated corticosteroids on sputum inflammatory markers in asthmatic patients
-
Hauber HP, Taha R, Bergeron C, etal. Effects of hydrofluoroalkane and dry powder-formulated corticosteroids on sputum inflammatory markers in asthmatic patients. Can Respir J. 2006;13: 73-8.
-
(2006)
Can Respir J.
, vol.13
, pp. 73-78
-
-
Hauber, H.P.1
Taha, R.2
Bergeron, C.3
-
23
-
-
34248577155
-
Differential flow analysis of exhaled nitric oxide in patients with asthma of differing severity
-
Brindicci C, Ito K, Barnes PJ, Kharitonov SA. Differential flow analysis of exhaled nitric oxide in patients with asthma of differing severity. Chest. 2007;131: 1353-62.
-
(2007)
Chest.
, vol.131
, pp. 1353-1362
-
-
Brindicci, C.1
Ito, K.2
Barnes, P.J.3
Kharitonov, S.A.4
-
24
-
-
77953090892
-
Effects of extra-fine inhaled beclomethasone/formoterol on both large and small airways in asthma
-
Schichilone N, Battaglia S, Sorino C, etal. Effects of extra-fine inhaled beclomethasone/formoterol on both large and small airways in asthma. Allergy. 2010;65: 897-902.
-
(2010)
Allergy.
, vol.65
, pp. 897-902
-
-
Schichilone, N.1
Battaglia, S.2
Sorino, C.3
-
25
-
-
77649271741
-
Inflammation and airway function in the lung periphery of patients with stable asthma
-
Verbanck S, Scheuermans D, Vincken W. Inflammation and airway function in the lung periphery of patients with stable asthma. J Allergy Clin Immunol. 2010;125: 611-6.
-
(2010)
J Allergy Clin Immunol.
, vol.125
, pp. 611-616
-
-
Verbanck, S.1
Scheuermans, D.2
Vincken, W.3
-
26
-
-
67349245921
-
Effect of inhaled corticosteroids on small airways in asthma: investigation using impulse oscillometry
-
Yamaguchi M, Niimi A, Ueda T, etal. Effect of inhaled corticosteroids on small airways in asthma: investigation using impulse oscillometry. Pulm Pharmacol Ther. 2009;22: 326-32.
-
(2009)
Pulm Pharmacol Ther.
, vol.22
, pp. 326-332
-
-
Yamaguchi, M.1
Niimi, A.2
Ueda, T.3
-
27
-
-
63449107671
-
Impulse oscillometry versus spirometry in a long-term study of controller therapy for pediatric asthma
-
Larsen GL, Morgan W, Heldt GP, etal. Impulse oscillometry versus spirometry in a long-term study of controller therapy for pediatric asthma. J Allergy Clin Immunol. 2009;123: 861-7.
-
(2009)
J Allergy Clin Immunol.
, vol.123
, pp. 861-867
-
-
Larsen, G.L.1
Morgan, W.2
Heldt, G.P.3
-
28
-
-
34547807610
-
Ventilation heterogeneity is a major determinant of airway hyperresponsiveness in asthma, independent of airway inflammation
-
Downie SR, Salome CM, Verbranck S, etal. Ventilation heterogeneity is a major determinant of airway hyperresponsiveness in asthma, independent of airway inflammation. Thorax. 2007;62: 684-9.
-
(2007)
Thorax.
, vol.62
, pp. 684-689
-
-
Downie, S.R.1
Salome, C.M.2
Verbranck, S.3
-
29
-
-
33750533197
-
Role of small airways in asthma: investigation using high-resolution computed tomography
-
Ueda T, Niimi A, Matsumoto H, etal. Role of small airways in asthma: investigation using high-resolution computed tomography. J Allergy Clin Immunol. 2006;118: 1019-25.
-
(2006)
J Allergy Clin Immunol.
, vol.118
, pp. 1019-1025
-
-
Ueda, T.1
Niimi, A.2
Matsumoto, H.3
-
30
-
-
0037841783
-
Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: assessment of response to methacholine and exercise challenge
-
Samee S, Altes T, Powers P, etal. Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: assessment of response to methacholine and exercise challenge. J Allergy Clin Immunol. 2003;111: 1205-11.
-
(2003)
J Allergy Clin Immunol.
, vol.111
, pp. 1205-1211
-
-
Samee, S.1
Altes, T.2
Powers, P.3
-
31
-
-
0033431716
-
Efficacy response of inhaled beclomethasone dipropionate in asthma is proportional to dose and is improved by formulation with a new propellant
-
Busse WW, Brazinsky S, Jacobson K, etal. Efficacy response of inhaled beclomethasone dipropionate in asthma is proportional to dose and is improved by formulation with a new propellant. J Allergy Clin Immunol. 1999;104: 1215-22.
-
(1999)
J Allergy Clin Immunol.
, vol.104
, pp. 1215-1222
-
-
Busse, W.W.1
Brazinsky, S.2
Jacobson, K.3
-
32
-
-
0031901949
-
Safety of hydrofluoalkane-134a beclomethasone dipropionate extrafine aerosol
-
Thompson PJ, Davies RJ, Young WF, etal. Safety of hydrofluoalkane-134a beclomethasone dipropionate extrafine aerosol. Respir Med. 1998;92: 33-9.
-
(1998)
Respir Med.
, vol.92
, pp. 33-39
-
-
Thompson, P.J.1
Davies, R.J.2
Young, W.F.3
-
33
-
-
0031903768
-
Hydrofluroalkane-134a beclomethasone dipropionate extrafine aerosol provides equivalent asthma control to chlorofluorocarbon beclomethasone dipropionate at approximately half the total daily dose
-
Davies RJ, Stampone P, O'Connor BJ. Hydrofluroalkane-134a beclomethasone dipropionate extrafine aerosol provides equivalent asthma control to chlorofluorocarbon beclomethasone dipropionate at approximately half the total daily dose. Respir Med. 1998;92: 23-31.
-
(1998)
Respir Med.
, vol.92
, pp. 23-31
-
-
Davies, R.J.1
Stampone, P.2
O'Connor, B.J.3
-
34
-
-
4344658666
-
The efficacy and safety of QVAR (hydrofluoroalkane-beclomethasone dipropionate extrafine aerosol) in asthma (part I): an update of clinical experience in adults
-
van Schayck CP, Donnell D. The efficacy and safety of QVAR (hydrofluoroalkane-beclomethasone dipropionate extrafine aerosol) in asthma (part I): an update of clinical experience in adults. Int J Clin Pract. 2004;58: 678-88.
-
(2004)
Int J Clin Pract.
, vol.58
, pp. 678-688
-
-
van Schayck, C.P.1
Donnell, D.2
-
35
-
-
34147160761
-
Beclomethasone/formoterol vs. budesonide/formoterol combination therapy in asthma
-
Papi A, Paggiaro PL, Nicolini G, etal. Beclomethasone/formoterol vs. budesonide/formoterol combination therapy in asthma. Eur Respir J. 2007;29: 682-89.
-
(2007)
Eur Respir J.
, vol.29
, pp. 682-689
-
-
Papi, A.1
Paggiaro, P.L.2
Nicolini, G.3
-
36
-
-
53749105516
-
Hydrofluoroalkane-Beclomethasone dipropionate effectively improves airway eosinophilic inflammation including the distal airways of patients with mild to moderate persistent asthma as compared with fluticasone propionate in a randomized open double-cross study
-
Ohbayashi H, Adachi M. Hydrofluoroalkane-Beclomethasone dipropionate effectively improves airway eosinophilic inflammation including the distal airways of patients with mild to moderate persistent asthma as compared with fluticasone propionate in a randomized open double-cross study. Allergology International. 2008;57: 1-9.
-
(2008)
Allergology International.
, vol.57
, pp. 1-9
-
-
Ohbayashi, H.1
Adachi, M.2
-
37
-
-
0036279645
-
Clinically important improvements in Asthma-Specific Quality of Life, but no difference in conventional clinical indexes in patients changed from conventional beclomethasone dipropionate to approximately half the dose of extrafine beclomethasone dipropionate
-
Juniper EF, Price DB, Stampone PA, etal. Clinically important improvements in Asthma-Specific Quality of Life, but no difference in conventional clinical indexes in patients changed from conventional beclomethasone dipropionate to approximately half the dose of extrafine beclomethasone dipropionate. Chest. 2002;121: 1824-32.
-
(2002)
Chest.
, vol.121
, pp. 1824-1832
-
-
Juniper, E.F.1
Price, D.B.2
Stampone, P.A.3
-
38
-
-
22044435423
-
Hydrofluoroalkane-134a beclomethasone or chlorofluorocarbon fluticasone: effect on small airways in poorly controlled asthma
-
Thongngarm T, Silkoff PE, Kossack WS, Nelson HS. Hydrofluoroalkane-134a beclomethasone or chlorofluorocarbon fluticasone: effect on small airways in poorly controlled asthma. J Asthma. 2005;42: 257-63.
-
(2005)
J Asthma.
, vol.42
, pp. 257-263
-
-
Thongngarm, T.1
Silkoff, P.E.2
Kossack, W.S.3
Nelson, H.S.4
-
39
-
-
0033407462
-
Comparative effects of hydrofluoroalkane and chlorofluorocarbon beclomethasone dipropionate inhalation on small airways: assessment with functional helical thinsection computed tomography
-
Goldin JG, Tashkin DP, Kleerup EC, etal. Comparative effects of hydrofluoroalkane and chlorofluorocarbon beclomethasone dipropionate inhalation on small airways: assessment with functional helical thinsection computed tomography. J Allergy Clin Immunol. 1999;104: S258-67.
-
(1999)
J Allergy Clin Immunol.
, vol.104
-
-
Goldin, J.G.1
Tashkin, D.P.2
Kleerup, E.C.3
-
40
-
-
33847370409
-
Air trapping in mild to moderate asthma: Effect of inhaled corticosteroids
-
Tunon-de-Lara JM, Laurent F, Giraud V, etal. Air trapping in mild to moderate asthma: Effect of inhaled corticosteroids. J Allergy Clin Immunol. 2007;119: 583-90.
-
(2007)
J Allergy Clin Immunol.
, vol.119
, pp. 583-590
-
-
Tunon-de-Lara, J.M.1
Laurent, F.2
Giraud, V.3
-
41
-
-
34248547426
-
Differential anti-inflammatory effects of large and small particle size inhaled corticosteroids in asthma
-
Menzies D, Nair A, Hopkinson P, etal. Differential anti-inflammatory effects of large and small particle size inhaled corticosteroids in asthma. Allergy. 2007;62: 661-7.
-
(2007)
Allergy.
, vol.62
, pp. 661-667
-
-
Menzies, D.1
Nair, A.2
Hopkinson, P.3
-
42
-
-
33847368556
-
One-year evaluation of the preventive effect of hydrofluoroalkane-beclomethasone dipropionate on eosinophilic inflammation of asthmatic peripheral airways
-
Ohbayashi H. One-year evaluation of the preventive effect of hydrofluoroalkane-beclomethasone dipropionate on eosinophilic inflammation of asthmatic peripheral airways. Respiration. 2007;74: 146-53.
-
(2007)
Respiration.
, vol.74
, pp. 146-153
-
-
Ohbayashi, H.1
-
43
-
-
77956392249
-
Prescribing practices and asthma control with hydrofluoroalkane-beclomethasone and fluticasone: a real-world observational study
-
Price D, Martin RJ, Barnes N, etal. Prescribing practices and asthma control with hydrofluoroalkane-beclomethasone and fluticasone: a real-world observational study. J Allergy Clin Immunol. 2010;126: 511-8.
-
(2010)
J Allergy Clin Immunol.
, vol.126
, pp. 511-518
-
-
Price, D.1
Martin, R.J.2
Barnes, N.3
-
44
-
-
1842370350
-
Effect of inhaled formoterol and budesonide on exacerbations of asthma
-
Pauwels RA, Lofdahl CG, Postma DS, etal. Effect of inhaled formoterol and budesonide on exacerbations of asthma. N Engl J Med. 1997;337: 1405-11.
-
(1997)
N Engl J Med.
, vol.337
, pp. 1405-1411
-
-
Pauwels, R.A.1
Lofdahl, C.G.2
Postma, D.S.3
-
45
-
-
58049218972
-
Lung function and asthma control with beclomethasone and formoterol in a single inhaler
-
Huchon G, Magnussen H, Chuchalin A, etal. Lung function and asthma control with beclomethasone and formoterol in a single inhaler. Respir Med. 2009;103: 41-9.
-
(2009)
Respir Med.
, vol.103
, pp. 41-49
-
-
Huchon, G.1
Magnussen, H.2
Chuchalin, A.3
|