One-year evaluation of the preventative effect of hydrofluoroalkane- beclomethasone dipropionate on eosinophilic inflammation of asthmatic peripheral airways

Respiration

Volumn 74, Issue 2, 2007, Pages 146-153

  Ohbayashi, Hiroyuki ^a  

^a Tohno Kousei Hospital   (Japan)

Author keywords

Bronchial asthma; Eosinophil cationic protein; Hydrofluoroalkane beclomethasone dipropionate; Peripheral airway

Indexed keywords

BECLOMETASONE DIPROPIONATE; BUDESONIDE; CORTICOSTEROID; DISKUS; EOSINOPHIL CATIONIC PROTEIN; EOTAXIN; FLUORINATED HYDROCARBON; FLUTICASONE PROPIONATE; RANTES; SODIUM CHLORIDE; TURBUHALER; UNCLASSIFIED DRUG;

AGED; ARTICLE; ASTHMA; CONTROLLED STUDY; DRUG EFFICACY; DRY POWDER; EOSINOPHIL COUNT; EVALUATION; FEMALE; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; OUTPATIENT; PATIENT COMPLIANCE; PRIORITY JOURNAL; TREATMENT DURATION;

ADMINISTRATION, INHALATION; AEROSOL PROPELLANTS; AGED; ASTHMA; BECLOMETHASONE; BRONCHITIS; EOSINOPHILIA; EOSINOPHILS; FEMALE; FOLLOW-UP STUDIES; GLUCOCORTICOIDS; HUMANS; HYDROCARBONS, FLUORINATED; LEUKOCYTE COUNT; MALE; MIDDLE AGED; SPUTUM; TIME FACTORS; TREATMENT OUTCOME; VITAL CAPACITY;

EID: 33847368556     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000094239     Document Type: Article

References (23)

1. National Institutes of Health and National Heart, Lung, and Blood Institute: Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. Bethesda, NIH, 2002, pp 102-114.
2. Makino S, Furusho K, Miyamoto A, Nishima S, Immunity/Allergy Study Group (eds): The 2003 Guidelines on the Prevention/Management of Asthma, ed 2. Tokyo, Ministry of Health, Labor and Welfare, 2003, pp 71-91.
3. Ohbayashi H: The evaluation of the relationship between the residual fluticasone propionate dry powder after inhalation and maximum peak inspiratory flow (in Japanese). Arerugi 2002;51:544-551.
4. Ohbayashi H: An evaluation of the acceptance of budesonide turbuhaler by older Japanese patients with bronchial asthma when changed from fluticasone propionate (FP) or beclomethasone dipropionate (BDP) (in Japanese). Arerugi 2003;52:31-38.
5. Hamid Q, Song Y, Kotsimbos TC, Minshall E, Bai TR, Hegele RG, Hogg JC: Inflammation of small airways in asthma. J Allergy Clin Immunol 1997;100:44-51.
6. Martin RJ: Therapeutic significance of distal airway inflammation in asthma. J Allergy Clin Immunol 2002;109:S447-S460.
7. Leach CL, Davidson PJ, Boudreau RJ: Improved airway targeting with the CFC-free HFA-beclomethasone metered-dose inhaler compared with CFC-beclomethasone. Eur Respir J 1998;12:1346-1353.
8. Ederle K, Multicentre Study Group: Improved control of asthma symptoms with a reduced dose of HFA-BDP extrafine aerosol: an open-label, randomised study. Eur Rev Med Pharmacol Sci 2003;7:45-55.
9. Bousquet J, Huchon G, Leclerc V, Vicaut E, Lefrançois GA: Randomized, double-blind, double-dummy, single-dose, efficacy cross-over trial comparing formoterol-HFA (pMDI) versus formoterol-DPI (Aerolizer TM ) and placebo (pMDI or Aerolizer TM ) in asthmatic patients. Respiration 2005;72:6-12.
10. Langley SJ, Houghton CM, Singh SD: Bronchoprotective and bronchodilator effects of an HFA pMDI vs a CFC pMDI and a DPI containing formoterol in asthma patients. Respiration 2005;72:35-37.
11. Gershman NH, Liu H, Wong HH, Liu JT, Fahy JV: Fractional analysis of sequential induced sputum samples during sputum induction: evidence that different lung compartments are sampled at different time points. J Allergy Clin Immunol 1999;104:322-328.
12. Fahy JV, Wong H, Liu J, Boushey HA: Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects. Am J Respir Crit Care Med 1995;152:53-58.
13. Leach CL: Improved delivery of inhaled steroids to the large and small airways. Respir Med 1998;92(suppl A):3-8.
14. Vanden Burgt JA, Busse WW, Martin RJ, Szefler SJ, Donnell D: Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma. J Allergy Clin Immunol 2000;106:1209-1226.
15. Fairfax A, Hall I, Spelman R: A randomized, double-blind comparison of beclomethasone dipropionate extrafine aerosol and fluticasone propionate. Ann Allergy Asthma Immunol 2001;86:575-582.
16. Worth H: A comparison of HFA-BDP Autohaler with budesonide Turbuhaler in asthma control of adult patients with mild to moderately severe disease. Respir Med 2000;94(suppl D):S27-S30.
17. Reichel W, Dahl R, Ringdal N, Zetterstrom O, van den Elshout FJ, Laitinen LA: Extrafine beclomethasone dipropionate breathactuated inhaler (400 micrograms/day) versus budesonide dry powder inhaler (800 micrograms/day) in asthma. Int J Clin Pract 2001;55:100-106.
18. Selroos O, Backman R, Forsen KO, Lofroos AB, Niemisto M, Pietinalho A, Riska H: Clinical efficacy of budesonide Turbuhaler compared with that of beclomethasone dipropionate pMDI with volumatic spacer. A 2-year randomized study in 102 asthma patients. Allergy 1994;49:833-836.
19. Davies RJ, Stampone P, O'Connor BJ: Hydrofluoroalkane-134a beclomethasone dipropionate extrafine aerosol provides equivalent asthma control to chlorofluorocarbon beclomethasone dipropionate at approximately half the total daily dose. Respir Med 1998;92(suppl A):23-31.
20. Gross G, Thompson PJ, Chervinsky P, Vanden Burgt J: Hydrofluoroalkane- 134a beclomethasone dipropionate, 400 microg, is as effective as chlorofluorocarbon beclomethasone dipropionate, 800 microg, for the treatment of moderate asthma. Chest 1999;115:343-351.
21. Dahl R, Lundback B, Malo JL, Mazza JA, Nieminen MM, Saarelainen P, Barnacle H: A dose-ranging study of fluticasone propionate in adult patients with moderate asthma. International Study Group. Chest 1993;104:1352-1358.
22. Barnes NC, Hallett C, Harris TA: Clinical experience with fluticasone propionate in asthma: a meta-analysis of efficacy and systemic activity compared with budesonide and beclomethasone dipropionate at half the microgram dose or less. Respir Med 1998;92:95-104.
23. Kuna P, Joubert JR, Greefhorst LA, Magnussen H: A randomized, double-blind, double-dummy, parallel-group, multicenter, dose-reduction trial of the minimal effective doses of budesonide and fluticasone dry-powder inhalers in adults with mild to moderate asthma. Clin Ther 2003;25:2182-2197.